DD238068A5 - Verfahren zur herstellung von derivaten der cyclopeptidantibiotika a-21978 c - Google Patents

Verfahren zur herstellung von derivaten der cyclopeptidantibiotika a-21978 c Download PDF

Info

Publication number: DD238068A5
Authority: DD; German Democratic Republic
Prior art keywords: culture; acid; fermentation; medium; hours
Prior art date: 1984-10-09

Application number

DD85281515A

Other languages

German (de)

English (en)

Inventor

Floyd M Huber

Richard L Pieper

Anthony J Tietz

Tom E Eaton

Lynda M Ford

Otis W Jun Godfrey

Mary L Huber

Milton J Jun Zmijewski

Original Assignee

��@��@�K@��k��

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-09

Filing date

1985-10-08

Publication date

1986-08-06

1985-10-08 Application filed by ��@��@�K@��k�� filed Critical ��@��@�K@��k��

1986-08-06 Publication of DD238068A5 publication Critical patent/DD238068A5/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
Biophysics (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
Virology (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Compounds Of Unknown Constitution (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Treating Waste Gases (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pyrane Compounds (AREA)

DD85281515A 1984-10-09 1985-10-08 Verfahren zur herstellung von derivaten der cyclopeptidantibiotika a-21978 c DD238068A5 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US65897984A	1984-10-09	1984-10-09

Publications (1)

Publication Number	Publication Date
DD238068A5 true DD238068A5 (de)	1986-08-06

Family

ID=24643546

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DD85281515A DD238068A5 (de)	1984-10-09	1985-10-08	Verfahren zur herstellung von derivaten der cyclopeptidantibiotika a-21978 c
DD86288284A DD247023A5 (de)	1984-10-09	1986-03-25	Verfahren zur herstellung des cyclopeptidantibiotikumkomplexes a-21978c oder von faktoren hiervon

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DD86288284A DD247023A5 (de)	1984-10-09	1986-03-25	Verfahren zur herstellung des cyclopeptidantibiotikumkomplexes a-21978c oder von faktoren hiervon

Country Status (27)

Country	Link
EP (1)	EP0178152B1 (fr)
JP (1)	JPH0787796B2 (fr)
KR (1)	KR890000800B1 (fr)
CN (2)	CN1051200A (fr)
AT (1)	ATE67788T1 (fr)
AU (2)	AU4837785A (fr)
BG (1)	BG47040A3 (fr)
CS (2)	CS276983B6 (fr)
CY (1)	CY1633A (fr)
DD (2)	DD238068A5 (fr)
DE (1)	DE3584218D1 (fr)
DK (2)	DK165416C (fr)
EG (1)	EG17619A (fr)
ES (2)	ES8700862A1 (fr)
FI (1)	FI82075C (fr)
GR (1)	GR852432B (fr)
HK (1)	HK24292A (fr)
HU (1)	HU196845B (fr)
IE (1)	IE58655B1 (fr)
IL (1)	IL76608A (fr)
NZ (1)	NZ213731A (fr)
PH (1)	PH21217A (fr)
PL (1)	PL152359B1 (fr)
PT (1)	PT81265B (fr)
SG (1)	SG3292G (fr)
SU (1)	SU1452484A3 (fr)
ZA (1)	ZA857759B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0294990A3 (fr) *	1987-06-10	1990-05-09	Eli Lilly And Company	Procédé de purification chromatographique
US4930494A (en) *	1988-03-09	1990-06-05	Olympus Optical Co., Ltd.	Apparatus for bending an insertion section of an endoscope using a shape memory alloy
US4977083A (en) *	1988-04-11	1990-12-11	Eli Lilly And Company	Processes for preparing A54145 compounds
DE3832362A1 (de) *	1988-09-23	1990-03-29	Sandoz Ag	Neue cyclopeptolide, verfahren zu ihrer herstellung und ihre verwendung
CN1425025A (zh)	1999-12-15	2003-06-18	卡比斯特制药公司	作为抗菌剂的新颖的脂肽
WO2001044274A1 (fr) *	1999-12-15	2001-06-21	Cubist Pharmaceuticals, Inc.	Lipopeptides utiles en tant qu'agents antibacteriens
US6696412B1 (en) *	2000-01-20	2004-02-24	Cubist Pharmaceuticals, Inc.	High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en)	2000-12-18	2006-01-19	Dennis Keith	Methods for preparing purified lipopeptides
BRPI0923567A2 (pt)	2008-12-22	2016-09-27	Cubist Pharm Inc	agentes antibactericidas novos para o tratamento de infecções gram positivas
RU2607526C2 (ru)	2009-11-23	2017-01-10	Кьюбист Фармасьютикалз ЭлЭлСи	Липопептидные композиции и родственные способы
CN103857440B (zh) *	2011-06-22	2018-09-25	维奥姆生物科学有限公司	基于缀合物的抗真菌和抗细菌前药
IT201600127655A1 (it)	2016-12-16	2018-06-16	Gnosis Spa	Processo per la purificazione di antibiotici lipopolipeptidici
CN107964557B (zh) *	2018-01-17	2020-11-20	自然资源部第三海洋研究所	一种提高芽孢杆菌抗菌脂肽产量的发酵方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4208403A (en) *	1978-10-16	1980-06-17	Eli Lilly And Company	A-21978 Antibiotics and process for their production
IL68700A0 (en) *	1982-05-21	1983-09-30	Lilly Co Eli	Improvements relating to a-21978c cyclic peptide derivatives and their production

1985
- 1985-10-08 SU SU853964395A patent/SU1452484A3/ru active
- 1985-10-08 AU AU48377/85A patent/AU4837785A/en not_active Abandoned
- 1985-10-08 JP JP60225925A patent/JPH0787796B2/ja not_active Expired - Lifetime
- 1985-10-08 CS CS868192A patent/CS276983B6/cs not_active IP Right Cessation
- 1985-10-08 KR KR1019850007397A patent/KR890000800B1/ko not_active Expired
- 1985-10-08 EP EP85307185A patent/EP0178152B1/fr not_active Expired - Lifetime
- 1985-10-08 ZA ZA857759A patent/ZA857759B/xx unknown
- 1985-10-08 DD DD85281515A patent/DD238068A5/de not_active IP Right Cessation
- 1985-10-08 FI FI853910A patent/FI82075C/fi not_active IP Right Cessation
- 1985-10-08 CS CS857198A patent/CS276978B6/cs not_active IP Right Cessation
- 1985-10-08 AT AT85307185T patent/ATE67788T1/de not_active IP Right Cessation
- 1985-10-08 PT PT81265A patent/PT81265B/pt unknown
- 1985-10-08 EG EG634/85A patent/EG17619A/xx active
- 1985-10-08 DE DE8585307185T patent/DE3584218D1/de not_active Expired - Lifetime
- 1985-10-08 PL PL1985255683A patent/PL152359B1/pl unknown
- 1985-10-08 CN CN90109304A patent/CN1051200A/zh active Pending
- 1985-10-08 IL IL76608A patent/IL76608A/xx not_active IP Right Cessation
- 1985-10-08 ES ES547689A patent/ES8700862A1/es not_active Expired
- 1985-10-08 BG BG071957A patent/BG47040A3/xx unknown
- 1985-10-08 NZ NZ213731A patent/NZ213731A/en unknown
- 1985-10-08 DK DK457585A patent/DK165416C/da not_active IP Right Cessation
- 1985-10-08 CN CN85107552A patent/CN1013120B/zh not_active Expired
- 1985-10-08 HU HU853912A patent/HU196845B/hu unknown
- 1985-10-08 GR GR852432A patent/GR852432B/el unknown
- 1985-10-08 PH PH32894A patent/PH21217A/en unknown
- 1985-10-08 IE IE246685A patent/IE58655B1/en not_active IP Right Cessation
1986
- 1986-03-25 DD DD86288284A patent/DD247023A5/de unknown
- 1986-04-01 ES ES553603A patent/ES8800362A1/es not_active Expired
1990
- 1990-04-20 AU AU53752/90A patent/AU634766B2/en not_active Expired
1991
- 1991-08-21 DK DK148791A patent/DK165757C/da not_active IP Right Cessation
1992
- 1992-01-11 SG SG32/92A patent/SG3292G/en unknown
- 1992-04-02 HK HK242/92A patent/HK24292A/en not_active IP Right Cessation
- 1992-11-06 CY CY1633A patent/CY1633A/xx unknown

Also Published As

Publication number	Publication date
EP0178152B1 (fr)	1991-09-25
DK148791A (da)	1991-08-21
SG3292G (en)	1992-03-20
DD247023A5 (de)	1987-06-24
CS276983B6 (en)	1992-11-18
EG17619A (en)	1991-03-30
PL255683A1 (en)	1986-07-29
ZA857759B (en)	1987-05-27
FI82075B (fi)	1990-09-28
DK165757B (da)	1993-01-11
ES547689A0 (es)	1986-11-16
BG47040A3 (en)	1990-04-16
FI82075C (fi)	1991-01-10
DK165416C (da)	1993-04-05
AU634766B2 (en)	1993-03-04
PT81265A (en)	1985-11-01
DK148791D0 (da)	1991-08-21
NZ213731A (en)	1988-04-29
AU5375290A (en)	1990-11-01
FI853910A0 (fi)	1985-10-08
IL76608A (en)	1991-03-10
ES553603A0 (es)	1987-11-01
FI853910L (fi)	1986-04-10
SU1452484A3 (ru)	1989-01-15
ATE67788T1 (de)	1991-10-15
HUT39782A (en)	1986-10-29
KR860003335A (ko)	1986-05-23
PT81265B (pt)	1988-02-17
DK165757C (da)	1993-06-07
JPS6192588A (ja)	1986-05-10
DK457585A (da)	1986-04-10
CS719885A3 (en)	1992-03-18
CN1051200A (zh)	1991-05-08
IE852466L (en)	1986-04-09
DK457585D0 (da)	1985-10-08
EP0178152A2 (fr)	1986-04-16
HK24292A (en)	1992-04-10
DE3584218D1 (de)	1991-10-31
ES8800362A1 (es)	1987-11-01
CN1013120B (zh)	1991-07-10
JPH0787796B2 (ja)	1995-09-27
IE58655B1 (en)	1993-11-03
PH21217A (en)	1987-08-21
HU196845B (en)	1989-01-30
CS819286A3 (en)	1992-03-18
DK165416B (da)	1992-11-23
AU4837785A (en)	1986-04-17
ES8700862A1 (es)	1986-11-16
CY1633A (en)	1992-11-06
GR852432B (fr)	1986-02-10
IL76608A0 (en)	1986-02-28
EP0178152A3 (en)	1988-11-02
CN85107552A (zh)	1987-05-20
PL152359B1 (en)	1990-12-31
CS276978B6 (en)	1992-11-18
KR890000800B1 (ko)	1989-04-07

Legal Events

Date	Code	Title	Description
2001-08-30	ENJ	Ceased due to non-payment of renewal fee

Publication	Publication Date	Title
DE3887820T2 (de)	1994-05-19	Antibiotika, Benanomicine A und B und Dexylosylbenanomicin B, ihre Herstellung und Verwendung.
DE2532568A1 (de)	1976-02-12	Aclacinomycine a und b und verfahren zu ihrer herstellung
DD238068A5 (de)	1986-08-06	Verfahren zur herstellung von derivaten der cyclopeptidantibiotika a-21978 c
DD146618A5 (de)	1981-02-18	Verfahren zur herstellung des antibiotikums
DE3873845T2 (de)	1993-02-04	Antimikrobielles agens, fr 109 615 und seine herstellung.
US4800157A (en)	1989-01-24	Process for producing the A-21978C antibiotics
CH668974A5 (de)	1989-02-15	Antitumor-antibiotikum.
DE2029768A1 (de)	1971-01-07	Anti Tumor Verbindung und ihre Her stellungsverfahren
EP0057349B1 (fr)	1984-06-27	Peptide-antibiotique, composante B, son procédé de préparation et son emploi dans des médicaments
DE2019838C3 (de)	1978-12-14	4-Hydroxy-5(3)-ribofuranosylpyrazol-3(5)-carboxamid und Verfahren zu seiner Herstellung
DE69114252T2 (de)	1996-04-11	Reveromycin-a, herstellung und verwendung als antitumormittel sowie als fungizid.
DE2120930A1 (de)	1971-11-18	Pepsin-Inhibitor und Verfahren zu dessen Herstellung
DE2455683A1 (de)	1975-06-05	Verfahren zur herstellung von deacetoxycephalosporin c
CH631740A5 (en)	1982-08-31	Process for the preparation of maytansinol and its derivatives
DE2638766A1 (de)	1977-07-14	Antibiotischer glykopeptidkomplex, verfahren zu seiner herstellung und diese enthaltende mittel
DE2921085C2 (fr)	1987-08-27
EP0304400B1 (fr)	1994-02-09	Dérivés de phénanthridine, procédé pour leur préparation et moyen pour suivre le procédé
DE2660964C2 (fr)	1987-07-16
DE69206858T2 (de)	1996-05-23	Verbindung UCA1064-B
DE69023804T2 (de)	1996-04-18	DC115A-Verbindungen mit antibakterieller und antitumor Wirkung.
EP0069882B1 (fr)	1984-06-13	Composés à activité antibiotique, procédé de leur préparation et leur emploi en tant que médicament
DE3882654T2 (de)	1993-12-16	Enzymhemmer und Methode zu dessen Herstellung.
DE3881566T2 (de)	1993-09-16	Antitumor-derivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten.
DE69423467T2 (de)	2000-09-07	Verbindung uch9
DE2746252A1 (de)	1978-10-05	Antibiotikum c-15003 enthaltendes arzneimittel zur behandlung von tumore aufweisenden warmbluetern