DD245727A5 - Ein verfahren zum nachweis und/oder messen klinischer parameter beim immunisierungsprozess von enzymen - Google Patents

Ein verfahren zum nachweis und/oder messen klinischer parameter beim immunisierungsprozess von enzymen Download PDF

Info

Publication number: DD245727A5
Authority: DD; German Democratic Republic
Prior art keywords: zone; enzyme; antibody; antigen; antibodies
Prior art date: 1985-02-08

Application number

DD86286799A

Other languages

German (de)

English (en)

Inventor

Ennio Iaccheri

Paola Piro

Claudio Manzati

Original Assignee

��@��@��@�K�K�Kk��

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-02-08

Filing date

1986-02-05

Publication date

1987-05-13

1986-02-05 Application filed by ��@��@��@�K�K�Kk�� filed Critical ��@��@��@�K�K�Kk��

1987-05-13 Publication of DD245727A5 publication Critical patent/DD245727A5/de

Links

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Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54391—Immunochromatographic test strips based on vertical flow

Landscapes

Health & Medical Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)
Investigating Or Analysing Biological Materials (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DD86286799A 1985-02-08 1986-02-05 Ein verfahren zum nachweis und/oder messen klinischer parameter beim immunisierungsprozess von enzymen DD245727A5 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT19443/85A IT1200382B (it)	1985-02-08	1985-02-08	Sistema di rilevazione e/o dosaggio di parametri clinici per via immuno enzimatica

Publications (1)

Publication Number	Publication Date
DD245727A5 true DD245727A5 (de)	1987-05-13

Family

ID=11158028

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DD86286799A DD245727A5 (de)	1985-02-08	1986-02-05	Ein verfahren zum nachweis und/oder messen klinischer parameter beim immunisierungsprozess von enzymen

Country Status (12)

Country	Link
EP (1)	EP0243370A1 (it)
JP (1)	JPS62501989A (it)
AU (1)	AU5511886A (it)
DD (1)	DD245727A5 (it)
ES (5)	ES8802256A1 (it)
FI (1)	FI85194C (it)
HU (1)	HUT56632A (it)
IT (1)	IT1200382B (it)
MW (1)	MW5287A1 (it)
OA (1)	OA08640A (it)
RO (1)	RO100056A2 (it)
WO (1)	WO1986004683A1 (it)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4806311A (en) *	1985-08-28	1989-02-21	Miles Inc.	Multizone analytical element having labeled reagent concentration zone
CA1289872C (en) *	1986-06-18	1991-10-01	David L. Woodrum	Reversible immobilization of assay reagents in a multizone test device
US4959305A (en) *	1986-06-18	1990-09-25	Miles Inc.	Reversible immobilization of assay reagents in a multizone test device
ES2004066A6 (es) *	1987-01-21	1988-12-01	Euro Fassel Aktiebolag	Metodo para analisis cualitativo y-o cuantitativo de antigenos,anticuerpos yno microorganismos u otras celulas y su correspondiente equipo
AU592174B2 (en) *	1987-02-17	1990-01-04	Genesis Labs, Inc.	Immunoassay test strip
AU586552B2 (en) *	1987-02-25	1989-07-13	Genesis Labs, Inc.	Dry test strip for devices using oxygen demanding detection system
DE3856421T2 (de) *	1987-04-27	2000-12-14	Unilever Nv	Spezifische Bindungstestverfahren
ATE86386T1 (de) *	1987-04-29	1993-03-15	Celltech Ltd	Vorrichtung fuer bindungstest.
US5641639A (en) *	1987-04-29	1997-06-24	Celltech Therapeutics Limited	Binding assay device
IT1223295B (it)	1987-08-14	1990-09-19	Boehringer Biochemia Srl	Dispositivo e metodo immunodiagnostico
FR2621393B1 (fr) *	1987-10-05	1991-12-13	Toledano Jacques	Dispositif de detection immunoenzymatique de substances a partir d'une goutte de sang ou de liquide provenant d'un quelconque milieu biologique
US5039607A (en) *	1988-05-17	1991-08-13	Syntex (U.S.A.) Inc.	Method for immunochromatographic analysis
US5334513A (en) *	1988-05-17	1994-08-02	Syntex (U.S.A.) Inc.	Method for immunochromatographic analysis
US5338513A (en) *	1988-07-30	1994-08-16	Boehringer Mannheim Gmbh	Test carrier for the analytical determination of a component of a liquid sample
FR2634891B1 (fr) *	1988-08-01	1994-05-06	Biotrol Laboratoires	Procede et dispositif pour la determination qualitative et/ou quantitative d'un ligand dans un fluide
US5079174A (en) *	1988-12-08	1992-01-07	Boehringer Mannheim Corporation	Apparatus for sequential determination of an analyte in a fluid sample
DE3842702A1 (de) *	1988-12-19	1990-06-21	Boehringer Mannheim Gmbh	Testtraeger zur analytischen untersuchung einer probenfluessigkeit mit hilfe einer spezifischen bindungsreaktion zweier bioaffiner bindungspartner und entsprechendes testverfahren
GB8903627D0 (en) *	1989-02-17	1989-04-05	Unilever Plc	Assays
US6352862B1 (en)	1989-02-17	2002-03-05	Unilever Patent Holdings B.V.	Analytical test device for imuno assays and methods of using same
JPH06508689A (ja) *	1991-06-13	1994-09-29	パシフィック・バイオテック・インコーポレイテッド	特異的リガンドを検出するための検定
DE4121493A1 (de) *	1991-06-28	1993-01-07	Draegerwerk Ag	Analysevorrichtung zur quantitativen, immunologischen bestimmung von schadstoffen
FI92882C (fi) *	1992-12-29	1995-01-10	Medix Biochemica Ab Oy	Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi
FR2725023B1 (fr) *	1994-09-28	1997-01-31	Gks Technologies	Diagnostic direct d'haptenes
JP3010699U (ja) *	1994-10-29	1995-05-02	株式会社ニッポンジーン	直接採尿の可能なクロマト式検査装置
FR2917171A1 (fr) *	2007-06-07	2008-12-12	Biosynex Sarl	Methode de detection d'une molecule d'interet dans un echantillon liquide.
CN102095860B (zh) *	2011-01-25	2013-12-18	厦门大学附属中山医院	梅毒特异性IgG抗体免疫印迹试剂盒及其制备方法
WO2021099550A1 (de)	2019-11-22	2021-05-27	Nano Scale Machining GmbH	Fluidmaschine, insbesondere hydromaschine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2644249A1 (de) *	1976-09-30	1978-04-06	Abbott Lab	Reaktive matrices
US4320111A (en) *	1977-06-14	1982-03-16	American Home Products Corporation	Immunologic compositions methods of preparation and use
US4189304A (en) *	1978-10-27	1980-02-19	Miles Laboratories, Inc.	Device and method for detecting myoglobin
US4331650A (en) *	1980-07-18	1982-05-25	Science Research Center, Inc.	Identification of reagins in the blood serum of allergen sensitized vertebrates
JPS5818167A (ja) *	1981-07-24	1983-02-02	Fuji Photo Film Co Ltd	分析フイルム及びこれを用いる分析方法
US4446232A (en) *	1981-10-13	1984-05-01	Liotta Lance A	Enzyme immunoassay with two-zoned device having bound antigens
US4447546A (en) *	1982-08-23	1984-05-08	Myron J. Block	Fluorescent immunoassay employing optical fiber in capillary tube
DE3484505D1 (de) *	1983-12-19	1991-05-29	Daiichi Pure Chemicals Co Ltd	Immuntest.

1985
- 1985-02-08 IT IT19443/85A patent/IT1200382B/it active
1986
- 1986-02-02 EP EP86901372A patent/EP0243370A1/en not_active Withdrawn
- 1986-02-02 AU AU55118/86A patent/AU5511886A/en not_active Abandoned
- 1986-02-02 JP JP61501288A patent/JPS62501989A/ja active Pending
- 1986-02-02 HU HU862003A patent/HUT56632A/hu unknown
- 1986-02-02 WO PCT/EP1986/000055 patent/WO1986004683A1/en not_active Ceased
- 1986-02-05 DD DD86286799A patent/DD245727A5/de not_active IP Right Cessation
- 1986-02-07 ES ES551760A patent/ES8802256A1/es not_active Expired
1987
- 1987-07-17 MW MW52/87A patent/MW5287A1/xx unknown
- 1987-07-22 OA OA59169A patent/OA08640A/xx unknown
- 1987-08-05 FI FI873398A patent/FI85194C/fi not_active IP Right Cessation
- 1987-08-13 ES ES557662A patent/ES8900067A1/es not_active Expired
1988
- 1988-01-11 RO RO131733A patent/RO100056A2/ro unknown
- 1988-01-15 ES ES557803A patent/ES8802259A1/es not_active Expired
- 1988-01-15 ES ES557802A patent/ES8802258A1/es not_active Expired
- 1988-02-01 ES ES557818A patent/ES8802260A1/es not_active Expired

Also Published As

Publication number	Publication date
EP0243370A1 (en)	1987-11-04
RO100056B1 (ro)	1990-10-30
FI85194C (fi)	1992-03-10
ES557802A0 (es)	1988-04-16
ES8802259A1 (es)	1988-04-16
IT1200382B (it)	1989-01-18
FI85194B (fi)	1991-11-29
ES551760A0 (es)	1988-04-16
ES8802260A1 (es)	1988-04-16
FI873398L (fi)	1987-08-05
ES557662A0 (es)	1988-11-16
JPS62501989A (ja)	1987-08-06
HUT56632A (en)	1991-09-30
MW5287A1 (en)	1988-11-09
AU5511886A (en)	1986-08-26
FI873398A0 (fi)	1987-08-05
ES8900067A1 (es)	1988-11-16
IT8519443A0 (it)	1985-02-08
OA08640A (en)	1988-11-30
ES557818A0 (es)	1988-04-16
ES8802258A1 (es)	1988-04-16
WO1986004683A1 (en)	1986-08-14
ES8802256A1 (es)	1988-04-16
RO100056A2 (ro)	1991-03-23
ES557803A0 (es)	1988-04-16

Legal Events

Date	Code	Title	Description
1994-01-27	EP	Request for examination under paragraph 12(1) filed
1995-09-14	WP12	As result of examination under paragraph 12 erstrg. patent revoked

Publication	Publication Date	Title
DD245727A5 (de)	1987-05-13	Ein verfahren zum nachweis und/oder messen klinischer parameter beim immunisierungsprozess von enzymen
DE69936916T2 (de)	2008-05-15	Liganden-bindetest und kit mit einer abtrennzone für störende probenkomponenten
DE69328120T2 (de)	2000-09-21	Prüfungsstreifen für immunoassays
DE68922148T2 (de)	1995-08-10	Ermittlungsverfahren und -gerät.
DE69816339T2 (de)	2004-06-09	Chromatographische vorrichtung und verfahren zum nachweis eines analyts in einer vollblutprobe
DE3879048T2 (de)	1993-09-02	Geraet fuer die laterale immunochromatographische bestimmung.
DE3586983T2 (de)	1993-04-29	Verfahren und vorrichtung fuer immunotest.
DE3887491T2 (de)	1994-07-07	Chromatographische Bindungstesteinrichtungen und Verfahren.
DE69227834T2 (de)	1999-04-29	Testvorrichtung
DE68911674T2 (de)	1994-04-07	Testverfahren und reagenzsatz dazu.
DE3686116T2 (de)	1993-01-28	Feststoffphase analytische einrichtung und verfahren zu ihrer verwendung.
DE69131933T2 (de)	2000-05-31	Testvorrictung für Liganden-Rezeptor- Verfahren
EP1644737B1 (de)	2008-10-08	Vorrichtung und verfahren zur simultanen durchführung von blutgruppenbestimmung, serumgegenprobe und antikörpersuch-test
DE69122832T2 (de)	1997-03-20	Vorrichtung zur Durchführung einer raschen einfachen Handprüfung
DE69330067T2 (de)	2001-08-23	Analytische testvorrichtung einschliesslich negativ- und positivkontrolle
DE3889833T2 (de)	1994-09-08	Diagnostische Vorrichtung und Verfahren, gekennzeichnet durch einen gezielten Durchfluss.
DE69530861T2 (de)	2004-05-06	Vorrichtung zur durchführung eines oder mehrerer kompetitiver immunoassays
DE3781335T2 (de)	1992-12-17	Immunoassay mit verwendung von kolloidalem gold.
DE2618386C2 (de)	1985-02-07	Diagnostisches Verfahren zum Bestimmen der Anwesenheit oder Abwesenheit nachzuweisender biologischer Teilchen
DE68920140T2 (de)	1995-08-03	Gerät und verfahren zur schnellen qualitativen und quantitativen bestimmung der anwesenheit eines reaktiven liganden in einer flüssigkeit.
DE69306804T2 (de)	1997-07-03	Immunologischer test auf festphase
DE68913086T2 (de)	1994-07-07	Qualitativer Enzymtest zur visuellen Auswertung.
EP0407904B1 (de)	1994-09-21	Verfahren zur Bestimmung eines Analyten
DE69920512T2 (de)	2006-02-23	Teststab für kohlenhydrat-freien transferrintest
DE10009503A1 (de)	2001-08-30	Verfahren zur Immobilisierung von Konjugaten in diagnostischen Tests