DD252187A5 - Verfahren zur herstellung von sulfonyl-phenylalkylaminen - Google Patents

Verfahren zur herstellung von sulfonyl-phenylalkylaminen Download PDF

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Publication number
DD252187A5
DD252187A5 DD86294889A DD29488986A DD252187A5 DD 252187 A5 DD252187 A5 DD 252187A5 DD 86294889 A DD86294889 A DD 86294889A DD 29488986 A DD29488986 A DD 29488986A DD 252187 A5 DD252187 A5 DD 252187A5
Authority
DD
German Democratic Republic
Prior art keywords
acid
group
ethyl
phenyl
chloro
Prior art date
Application number
DD86294889A
Other languages
German (de)
English (en)
Inventor
Ernst-Christian Witte
Hans-Peter Wolff
Karlheinz Stegmeier
Johannes Pill
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ��@���������@�������k�� filed Critical ��@���������@�������k��
Publication of DD252187A5 publication Critical patent/DD252187A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/38Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
DD86294889A 1985-10-02 1986-10-01 Verfahren zur herstellung von sulfonyl-phenylalkylaminen DD252187A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853535167 DE3535167A1 (de) 1985-10-02 1985-10-02 Neue sulfonyl-phenyl(alkyl)amine, verfahren zu ihrer herstellung sowie arzneimittel

Publications (1)

Publication Number Publication Date
DD252187A5 true DD252187A5 (de) 1987-12-09

Family

ID=6282575

Family Applications (1)

Application Number Title Priority Date Filing Date
DD86294889A DD252187A5 (de) 1985-10-02 1986-10-01 Verfahren zur herstellung von sulfonyl-phenylalkylaminen

Country Status (16)

Country Link
US (1) US4948809A (pl)
EP (1) EP0221344B1 (pl)
JP (1) JPH0710827B2 (pl)
KR (1) KR870003977A (pl)
AT (1) ATE53015T1 (pl)
AU (1) AU597000B2 (pl)
DD (1) DD252187A5 (pl)
DE (2) DE3535167A1 (pl)
DK (1) DK468786A (pl)
ES (1) ES2036168T3 (pl)
FI (1) FI863956A7 (pl)
HU (1) HU201735B (pl)
IL (1) IL80172A0 (pl)
PL (1) PL147258B1 (pl)
PT (1) PT83479B (pl)
ZA (1) ZA867442B (pl)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0194548A3 (de) * 1985-03-12 1988-08-17 Dr. Karl Thomae GmbH Neue Sulfonylaminoäthylverbindungen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
GB8528398D0 (en) * 1985-11-19 1985-12-24 Glaxo Group Ltd Chemical compounds
IL83230A (en) * 1986-08-06 1992-06-21 Tanabe Seiyaku Co Phenoxyacetic acid derivatives,their preparation and pharmaceutical compositions containing them
GB8708233D0 (en) * 1987-04-07 1987-05-13 Smith Kline French Lab Pharmaceutically active compounds
DE3819052A1 (de) * 1988-06-04 1989-12-07 Basf Ag Neue sulfonamid-derivate, ihre herstellung und verwendung
DE3829455A1 (de) * 1988-08-31 1990-03-15 Boehringer Mannheim Gmbh Sulfonamidoalkyl-cyclohexan-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel
US5280043A (en) * 1988-10-10 1994-01-18 Smith Kline & French Laboratories Ltd. Sulphonamido containing phenylalkanoic acids as thromboxane A2 antagonists
US5041232A (en) * 1990-03-16 1991-08-20 Lever Brothers Company, Division Of Conopco, Inc. Sulfonimines as bleach catalysts
US5189211A (en) * 1990-08-01 1993-02-23 Taisho Pharmaceutical Co., Ltd. Sulfonamide derivatives
DE4109735A1 (de) * 1991-03-25 1992-10-01 Boehringer Mannheim Gmbh Neue sulfonamide, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
JPH0753505A (ja) * 1992-10-01 1995-02-28 Hokuriku Seiyaku Co Ltd ベンゼンスルホンアミド誘導体及びその用途
AU5772196A (en) * 1995-05-19 1996-11-29 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
WO1996036595A1 (en) * 1995-05-19 1996-11-21 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
US6653331B2 (en) * 1996-07-03 2003-11-25 Pharmacia & Upjohn Company Targeted drug delivery using sulfonamide derivatives
GB9702194D0 (en) * 1997-02-04 1997-03-26 Lilly Co Eli Sulphonide derivatives
US6693137B1 (en) 1998-07-31 2004-02-17 Eli Lilly And Company Sulphonamide derivatives
WO2000059876A1 (en) * 1999-03-31 2000-10-12 Kissei Pharmaceutical Co., Ltd. 3-amidinobenzenesulfonamide derivatives, medicinal compositions containing the same and intermediates in the production thereof
SI1249233T1 (sl) * 1999-11-26 2009-02-28 Shionogi & Co Antagonisti NPYY5
WO2002039958A2 (en) 2000-11-03 2002-05-23 Tularik Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
FR2817256B1 (fr) * 2000-11-27 2005-07-15 Univ Pasteur Derives de l'acides 4-hydroxybutanoique et de son homologue superieur comme ligands des recepteurs du gamma- hydroxybutyrate (ghb), compositions pharmaceutiques les contenant et utilisations pharmaceutiques
SE0402635D0 (sv) * 2004-10-29 2004-10-29 Astrazeneca Ab Chemical compounds
US20090093485A1 (en) * 2004-10-29 2009-04-09 Astrazeneca Ab Novel Sulphonamide Derivatives as Glucocorticoid Receptor Modulators for the Treatment of Inflammatory Diseases
FI20055498A0 (fi) * 2005-09-16 2005-09-16 Biotie Therapies Corp Sulfonamidijohdannaisia
TW200815361A (en) * 2005-10-20 2008-04-01 Astrazeneca Ab Chemical compounds
US7750103B2 (en) * 2006-09-08 2010-07-06 The University Of Massachusetts Cyclooctene monomers and polymers, and water purification articles and methods utilizing them
TW200829578A (en) 2006-11-23 2008-07-16 Astrazeneca Ab Chemical compounds 537
JO2754B1 (en) * 2006-12-21 2014-03-15 استرازينكا ايه بي Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders
GB0705400D0 (en) * 2007-03-21 2007-05-02 Univ Aberdeen Therapeutic compounds andm their use
EP2240024A4 (en) * 2008-01-15 2014-05-21 Wellstat Therapeutics Corp COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
UY31832A (es) 2008-05-20 2010-01-05 Astrazeneca Ab Derivados de indazol sustituidos con fenilo y benzodioxinilo
GB0817207D0 (en) 2008-09-19 2008-10-29 Pimco 2664 Ltd therapeutic apsac compounds and their use
GB0817208D0 (en) * 2008-09-19 2008-10-29 Pimco 2664 Ltd Therapeutic apsap compounds and their use
ES2352398B1 (es) * 2009-06-25 2011-09-29 Institut Univ. De Ciencia I Tecnologia S.A. N-fenetilsulfonamidas-n-sustituidas para la identificacion de actividad biologica y farmacologica.
GB201311361D0 (en) 2013-06-26 2013-08-14 Pimco 2664 Ltd Compounds and their therapeutic use
AU2015367528B2 (en) 2014-12-17 2020-05-14 Pimco 2664 Limited N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and their therapeutic use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2809377A1 (de) * 1978-03-04 1979-09-13 Boehringer Mannheim Gmbh Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
US4219668A (en) * 1979-07-05 1980-08-26 American Cyanamid Company 4-Hydroxy,4-biphenylbutyric acid
DE3000377A1 (de) * 1980-01-07 1981-07-09 Boehringer Mannheim Gmbh, 6800 Mannheim Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
US4657929A (en) * 1983-10-25 1987-04-14 Fisons Plc Compounds
EP0194548A3 (de) * 1985-03-12 1988-08-17 Dr. Karl Thomae GmbH Neue Sulfonylaminoäthylverbindungen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
ATE53015T1 (de) 1990-06-15
FI863956A0 (fi) 1986-09-30
DK468786A (da) 1987-04-03
AU597000B2 (en) 1990-05-24
DK468786D0 (da) 1986-10-01
HU201735B (en) 1990-12-28
HUT43811A (en) 1987-12-28
KR870003977A (ko) 1987-05-06
JPS6284054A (ja) 1987-04-17
JPH0710827B2 (ja) 1995-02-08
PT83479B (de) 1988-11-02
US4948809A (en) 1990-08-14
ES2036168T3 (es) 1993-05-16
IL80172A0 (en) 1986-12-31
ZA867442B (en) 1987-06-24
DE3671440D1 (de) 1990-06-28
PL261644A1 (en) 1988-03-03
EP0221344B1 (de) 1990-05-23
PT83479A (de) 1986-11-01
DE3535167A1 (de) 1987-04-09
FI863956A7 (fi) 1987-04-03
AU6346386A (en) 1987-04-16
PL147258B1 (en) 1989-05-31
EP0221344A1 (de) 1987-05-13

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