DD263775A5 - Verfahren zur herstellung ungesaettigter aminosaeuren - Google Patents

Verfahren zur herstellung ungesaettigter aminosaeuren Download PDF

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Publication number
DD263775A5
DD263775A5 DD87299843A DD29984387A DD263775A5 DD 263775 A5 DD263775 A5 DD 263775A5 DD 87299843 A DD87299843 A DD 87299843A DD 29984387 A DD29984387 A DD 29984387A DD 263775 A5 DD263775 A5 DD 263775A5
Authority
DD
German Democratic Republic
Prior art keywords
amino
hydroxy
hydrogen
formula
alkyl
Prior art date
Application number
DD87299843A
Other languages
German (de)
English (en)
Inventor
Christof Angst
Derek E Brundish
John G Dingwall
Graham E Fagg
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ���@����������@��k�� filed Critical ���@����������@��k��
Publication of DD263775A5 publication Critical patent/DD263775A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3826—Acyclic unsaturated acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/302—Acyclic unsaturated acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/32—Esters thereof
    • C07F9/3205—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/3217—Esters of acyclic unsaturated acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4015—Esters of acyclic unsaturated acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
DD87299843A 1986-02-13 1987-02-11 Verfahren zur herstellung ungesaettigter aminosaeuren DD263775A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH57886 1986-02-13

Publications (1)

Publication Number Publication Date
DD263775A5 true DD263775A5 (de) 1989-01-11

Family

ID=4190244

Family Applications (1)

Application Number Title Priority Date Filing Date
DD87299843A DD263775A5 (de) 1986-02-13 1987-02-11 Verfahren zur herstellung ungesaettigter aminosaeuren

Country Status (23)

Country Link
EP (1) EP0233154B1 (da)
JP (2) JPH0717665B2 (da)
KR (1) KR900003533B1 (da)
AT (1) ATE70535T1 (da)
AU (1) AU610493B2 (da)
CA (1) CA1331625C (da)
CY (1) CY1821A (da)
DD (1) DD263775A5 (da)
DE (1) DE3775229D1 (da)
DK (1) DK169341B1 (da)
ES (1) ES2038690T3 (da)
FI (1) FI85144C (da)
GR (1) GR3003526T3 (da)
HK (1) HK95594A (da)
HU (1) HU204532B (da)
IE (1) IE59417B1 (da)
IL (1) IL81543A0 (da)
NO (1) NO170938C (da)
NZ (1) NZ219255A (da)
PH (1) PH23762A (da)
PT (1) PT84270B (da)
SG (1) SG92294G (da)
ZA (1) ZA871022B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175344A (en) * 1986-02-13 1992-12-29 Ciba-Geigy Corporation Unsaturated amino acids
PT85874B (pt) * 1986-10-09 1990-07-31 Ciba Geigy Ag Processo para a preparacao de oligo-peptidos com accao antibiotica
EP0302826A3 (de) * 1987-08-04 1991-04-03 Ciba-Geigy Ag Verfahren zur Herstellung neuer ungesättigter Aminosäureverbindungen
US5175153A (en) * 1987-11-30 1992-12-29 Warner-Lambert Company Substituted alpha-amino acids having pharmaceutical activity
US5179085A (en) * 1989-03-15 1993-01-12 Warner-Lambert Company N-substituted α-amino acids and derivatives thereof having pharmaceutical activity
DE59007300D1 (de) * 1989-04-07 1994-11-03 Ciba Geigy Ag Ungesättigte Aminodicarbonsäurederivate.
US5500419A (en) * 1989-09-19 1996-03-19 Merrell Dow Pharmaceuticals Inc. NMDA antagonists
EP0420806B1 (de) * 1989-09-26 1995-07-05 Ciba-Geigy Ag Phosphonsäure, Verfahren zur Herstellung und Verwendung als Arzneimittelwirkstoff
US5294734A (en) * 1989-09-26 1994-03-15 Ciba-Geigy Corp. 4-substituted 2-aminoalk-3-enoic acids
US5488140A (en) * 1989-09-26 1996-01-30 Ciba-Geigy Corporation 4-substituted 2-aminoalk-3-enoic
US5238958A (en) * 1990-02-26 1993-08-24 Warner-Lambert Company Substituted α-amino acids having selected acidic moieties for use as excitatory amino acid antagonists in pharmaceuticals
JPH07505908A (ja) * 1992-09-28 1995-06-29 マックセチーニ、マリア ルイザ Nmda受容体のアロステリックモジュレーター
CA2626435A1 (en) * 2005-10-18 2007-05-10 Centre National De La Recherche Scientifique (Cnrs) Hypophosphorous acid derivatives and their therapeutical applications
DE102007032669A1 (de) * 2007-07-13 2009-01-15 Clariant International Limited Alkylphosphonigsäuren, -salze und -ester, Verfahren zu deren Herstellung und ihre Verwendung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4477391A (en) 1981-08-14 1984-10-16 Collins James F Amino acid isomers, their production and their medicinal use
GB2104079B (en) * 1981-08-14 1985-08-21 London Polytech New aminoacid isomers, their production and their medicinal use

Also Published As

Publication number Publication date
NO170938B (no) 1992-09-21
HK95594A (en) 1994-09-16
HU204532B (en) 1992-01-28
IL81543A0 (en) 1987-09-16
ES2038690T3 (es) 1993-08-01
KR870007942A (ko) 1987-09-23
PH23762A (en) 1989-11-03
DK70787D0 (da) 1987-02-12
NO170938C (no) 1992-12-30
FI85144B (fi) 1991-11-29
FI85144C (fi) 1992-03-10
NO870577L (no) 1987-08-14
HUT43863A (en) 1987-12-28
FI870558A0 (fi) 1987-02-11
EP0233154A3 (en) 1989-06-14
FI870558A7 (fi) 1987-08-14
DE3775229D1 (de) 1992-01-30
NO870577D0 (no) 1987-02-13
IE870365L (en) 1987-08-13
PT84270B (pt) 1989-09-14
JPH07206683A (ja) 1995-08-08
GR3003526T3 (da) 1993-03-16
JPH0717665B2 (ja) 1995-03-01
CY1821A (en) 1995-10-20
DK169341B1 (da) 1994-10-10
EP0233154B1 (de) 1991-12-18
IE59417B1 (en) 1994-02-23
JPS62246586A (ja) 1987-10-27
SG92294G (en) 1995-04-28
EP0233154A2 (de) 1987-08-19
ZA871022B (en) 1987-09-30
CA1331625C (en) 1994-08-23
NZ219255A (en) 1989-08-29
AU6872687A (en) 1987-08-20
JP2509465B2 (ja) 1996-06-19
KR900003533B1 (ko) 1990-05-21
PT84270A (en) 1987-03-01
DK70787A (da) 1987-08-14
ATE70535T1 (de) 1992-01-15
AU610493B2 (en) 1991-05-23

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