DD277275A5 - Verfahren zur herstellung von acyl-derivaten von hydroxypyrimidinen - Google Patents

Verfahren zur herstellung von acyl-derivaten von hydroxypyrimidinen Download PDF

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Publication number
DD277275A5
DD277275A5 DD88322482A DD32248288A DD277275A5 DD 277275 A5 DD277275 A5 DD 277275A5 DD 88322482 A DD88322482 A DD 88322482A DD 32248288 A DD32248288 A DD 32248288A DD 277275 A5 DD277275 A5 DD 277275A5
Authority
DD
German Democratic Republic
Prior art keywords
substituted
phenyl
dimethyl
alkyl
phenylalkyl
Prior art date
Application number
DD88322482A
Other languages
German (de)
English (en)
Inventor
Frederick J Walker
John L Lamattina
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@���Kk�� filed Critical ������@���Kk��
Publication of DD277275A5 publication Critical patent/DD277275A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Liquid Carbonaceous Fuels (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Liquid Crystal Substances (AREA)
DD88322482A 1987-12-02 1988-12-01 Verfahren zur herstellung von acyl-derivaten von hydroxypyrimidinen DD277275A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/003171 WO1989005295A1 (en) 1987-12-02 1987-12-02 Acyl derivatives of hydroxypyrimidines

Publications (1)

Publication Number Publication Date
DD277275A5 true DD277275A5 (de) 1990-03-28

Family

ID=22202696

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88322482A DD277275A5 (de) 1987-12-02 1988-12-01 Verfahren zur herstellung von acyl-derivaten von hydroxypyrimidinen

Country Status (26)

Country Link
EP (1) EP0319170B1 (ja)
JP (1) JPH0725740B2 (ja)
KR (1) KR910000415B1 (ja)
CN (1) CN1033379A (ja)
AT (1) ATE86983T1 (ja)
AU (1) AU609547B2 (ja)
CA (1) CA1336516C (ja)
DD (1) DD277275A5 (ja)
DE (1) DE3879410T2 (ja)
DK (1) DK671188A (ja)
EG (1) EG19003A (ja)
ES (1) ES2053769T3 (ja)
FI (1) FI893648A7 (ja)
HU (1) HU206203B (ja)
IE (1) IE63456B1 (ja)
IL (1) IL88512A0 (ja)
MX (1) MX14001A (ja)
MY (1) MY103499A (ja)
NO (1) NO893105L (ja)
NZ (1) NZ227163A (ja)
PL (1) PL158165B1 (ja)
PT (1) PT89124B (ja)
RU (1) RU2036909C1 (ja)
WO (1) WO1989005295A1 (ja)
YU (1) YU47013B (ja)
ZA (1) ZA888969B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE133545T1 (de) * 1988-12-21 1996-02-15 Massachusetts Inst Technology Verfahren für laserinduzierte fluoreszenz von gewebe
US5270319A (en) * 1991-09-09 1993-12-14 Warner-Lambert Company 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents
US5220025A (en) * 1992-02-24 1993-06-15 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-butyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US5196431A (en) * 1992-02-24 1993-03-23 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-buthyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
TW440563B (en) * 1996-05-23 2001-06-16 Hoffmann La Roche Aryl pyrimidine derivatives and a pharmaceutical composition thereof
AU2003232650A1 (en) * 2003-05-06 2004-11-26 Il Yang Pharm Co., Ltd. N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof
KR20170057191A (ko) * 2017-05-04 2017-05-24 김점식 유압을 이용한 전기 자동차 구동장치

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554276A (en) * 1983-10-03 1985-11-19 Pfizer Inc. 2-Amino-5-hydroxy-4-methylpyrimidine derivatives
US4711888A (en) * 1985-07-24 1987-12-08 Pfizer Inc. Hydroxy and alkoxy pyrimidines

Also Published As

Publication number Publication date
EP0319170B1 (en) 1993-03-17
HU894552D0 (en) 1990-11-28
YU47013B (sh) 1994-11-15
EP0319170A3 (en) 1990-08-01
NO893105L (no) 1989-09-27
MX14001A (es) 1993-06-01
FI893648A0 (fi) 1989-08-01
DE3879410D1 (de) 1993-04-22
NZ227163A (en) 1990-11-27
RU2036909C1 (ru) 1995-06-09
YU217988A (en) 1990-10-31
PL276122A1 (en) 1989-06-12
EP0319170A2 (en) 1989-06-07
DK671188D0 (da) 1988-12-01
PT89124B (pt) 1993-04-30
IL88512A0 (en) 1989-06-30
KR910000415B1 (ko) 1991-01-25
CN1033379A (zh) 1989-06-14
ATE86983T1 (de) 1993-04-15
MY103499A (en) 1993-06-30
NO893105D0 (no) 1989-08-01
WO1989005295A1 (en) 1989-06-15
JPH0725740B2 (ja) 1995-03-22
JPH01250364A (ja) 1989-10-05
AU609547B2 (en) 1991-05-02
ES2053769T3 (es) 1994-08-01
FI893648A7 (fi) 1989-08-01
CA1336516C (en) 1995-08-01
IE63456B1 (en) 1995-04-19
AU2647088A (en) 1989-06-08
PT89124A (pt) 1988-12-01
ZA888969B (en) 1990-07-25
DK671188A (da) 1989-07-28
HU206203B (en) 1992-09-28
IE883598L (en) 1989-06-02
DE3879410T2 (de) 1993-06-24
HUT55003A (en) 1991-04-29
EG19003A (en) 1994-06-30
PL158165B1 (pl) 1992-08-31
KR890009890A (ko) 1989-08-04

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Legal Events

Date Code Title Description
NPV Change in the person, the name or the address of the representative (addendum to changes before extension act)
ENJ Ceased due to non-payment of renewal fee