DD284047A5 - Verfahren zur herstellung einer dna-sequenz, die fuer einen alkohol-oxidose-ii-regulationsbereich einer methylotrophen hefe kodiert - Google Patents
Verfahren zur herstellung einer dna-sequenz, die fuer einen alkohol-oxidose-ii-regulationsbereich einer methylotrophen hefe kodiert Download PDFInfo
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- DD284047A5 DD284047A5 DD89329825A DD32982589A DD284047A5 DD 284047 A5 DD284047 A5 DD 284047A5 DD 89329825 A DD89329825 A DD 89329825A DD 32982589 A DD32982589 A DD 32982589A DD 284047 A5 DD284047 A5 DD 284047A5
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- DD
- German Democratic Republic
- Prior art keywords
- dna
- regulatory region
- aox2
- gene
- plasmid
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- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 238000010188 recombinant method Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000021670 response to stimulus Effects 0.000 description 1
- 239000007320 rich medium Substances 0.000 description 1
- IOVGROKTTNBUGK-SJCJKPOMSA-N ritodrine Chemical compound N([C@@H](C)[C@H](O)C=1C=CC(O)=CC=1)CCC1=CC=C(O)C=C1 IOVGROKTTNBUGK-SJCJKPOMSA-N 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000011218 seed culture Methods 0.000 description 1
- 239000006152 selective media Substances 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
- 229940063673 spermidine Drugs 0.000 description 1
- 230000028070 sporulation Effects 0.000 description 1
- 239000007362 sporulation medium Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- 239000011721 thiamine Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 239000012137 tryptone Substances 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/211,007 US5032516A (en) | 1985-10-25 | 1988-06-24 | Pichia pastoris alcohol oxidase II regulatory region |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD284047A5 true DD284047A5 (de) | 1990-10-31 |
Family
ID=22785222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD89329825A DD284047A5 (de) | 1988-06-24 | 1989-06-21 | Verfahren zur herstellung einer dna-sequenz, die fuer einen alkohol-oxidose-ii-regulationsbereich einer methylotrophen hefe kodiert |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5032516A (fr) |
| EP (1) | EP0347928A3 (fr) |
| JP (1) | JPH0773501B2 (fr) |
| KR (1) | KR960010590B1 (fr) |
| CN (1) | CN1039616A (fr) |
| AU (1) | AU615078B2 (fr) |
| CA (1) | CA1306211C (fr) |
| DD (1) | DD284047A5 (fr) |
| DK (1) | DK175822B1 (fr) |
| FI (1) | FI104497B (fr) |
| HU (1) | HUT51673A (fr) |
| IE (1) | IE67039B1 (fr) |
| MX (1) | MX16518A (fr) |
| NO (1) | NO301285B1 (fr) |
| NZ (1) | NZ229534A (fr) |
| PH (1) | PH27314A (fr) |
| PT (1) | PT90970A (fr) |
| YU (1) | YU128789A (fr) |
| ZA (1) | ZA894495B (fr) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992013951A1 (fr) * | 1991-02-04 | 1992-08-20 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Production de serumalbumine humaine dans des cellules de levure methylotrophique |
| JPH07106153B2 (ja) * | 1991-03-27 | 1995-11-15 | 株式会社ミドリ十字 | 変異型ａｏｘ２プロモーターを担持するプラスミド、形質転換体および異種蛋白質の製造方法 |
| CA2063890C (fr) * | 1991-03-27 | 2007-03-13 | Masami Miura | Promoteur aox2 mutant, microorganisme le renfermant, methode pour le preparer et production d'une proteine heterologue a l'aide de ce microorganisme |
| JPH0829102B2 (ja) * | 1991-03-27 | 1996-03-27 | 株式会社ミドリ十字 | 変異型ａｏｘ２プロモーター、当該プロモーターを担持する菌株、その取得方法およびその菌株を利用した異種蛋白質の製造方法 |
| JP3505743B2 (ja) * | 1993-07-27 | 2004-03-15 | 三菱ウェルファーマ株式会社 | 変異型ａｏｘ２プロモーター、それを担持するベクター、形質転換体および異種蛋白質の製造方法 |
| IT1270196B (it) * | 1994-06-09 | 1997-04-29 | Enichem Spa | Procedimento catalitico per la produzione di ossime |
| US5866543A (en) * | 1995-06-05 | 1999-02-02 | Corvas International, Inc. | Nematode-extracted anticoagulant protein |
| US5872098A (en) * | 1995-06-05 | 1999-02-16 | Corvas International, Inc. | Nematode-extracted anticoagulant protein |
| US5945275A (en) * | 1994-10-18 | 1999-08-31 | Corvas International, Inc. | Nematode-extracted anticoagulant protein |
| EP0788546B9 (fr) * | 1994-10-18 | 2007-06-13 | Dendreon Corporation | Proteines anticoagulantes et inhibiteurs de la serine-protease extraits de nematodes |
| US5866542A (en) * | 1994-10-18 | 1999-02-02 | Corvas International, Inc. | Nematode-extracted anticoagulant protein |
| CA2202351A1 (fr) * | 1994-10-18 | 1996-04-25 | George Phillip Vlasuk | Proteines anticoagulantes et inhibiteurs de la serine-protease extraits de nematodes |
| US5863894A (en) * | 1995-06-05 | 1999-01-26 | Corvas International, Inc. | Nematode-extracted anticoagulant protein |
| US5965389A (en) * | 1995-11-09 | 1999-10-12 | Zymogenetics, Inc. | Production of GAD65 in methylotrophic yeast |
| MX9605082A (es) | 1996-10-24 | 1998-04-30 | Univ Autonoma De Nuevo Leon | Levaduras metilotroficas modificadas geneticamente para la produccion y secrecion de hormona de crecimiento humano. |
| US8697394B2 (en) * | 2000-06-28 | 2014-04-15 | Glycofi, Inc. | Production of modified glycoproteins having multiple antennary structures |
| US7863020B2 (en) * | 2000-06-28 | 2011-01-04 | Glycofi, Inc. | Production of sialylated N-glycans in lower eukaryotes |
| US7625756B2 (en) | 2000-06-28 | 2009-12-01 | GycoFi, Inc. | Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells |
| US7449308B2 (en) * | 2000-06-28 | 2008-11-11 | Glycofi, Inc. | Combinatorial DNA library for producing modified N-glycans in lower eukaryotes |
| ES2252261T3 (es) * | 2000-06-28 | 2006-05-16 | Glycofi, Inc. | Metodos para producir glicoproteinas modificadas. |
| US7598055B2 (en) * | 2000-06-28 | 2009-10-06 | Glycofi, Inc. | N-acetylglucosaminyltransferase III expression in lower eukaryotes |
| EP1385866A4 (fr) | 2001-04-05 | 2006-03-29 | Univ Nebraska | Sequences nucleotidiques regulatrices d'alcool oxydase 1 pour l'expression de genes heterologues dans une levure |
| DE60335602D1 (de) * | 2002-12-18 | 2011-02-17 | Roche Diagnostics Gmbh | Rekombinante Desoxyribonuclease I aus Rinder-Pankreas mit hoher spezifischer Aktivität |
| ATE387494T1 (de) * | 2002-12-20 | 2008-03-15 | Hoffmann La Roche | Hitzelabile desoxyribonuklease i-varianten |
| US7332299B2 (en) | 2003-02-20 | 2008-02-19 | Glycofi, Inc. | Endomannosidases in the modification of glycoproteins in eukaryotes |
| EP1460425A1 (fr) * | 2003-03-17 | 2004-09-22 | Boehringer Mannheim Gmbh | Enzymes déglycosylés pour conjugués |
| ES2337684T3 (es) * | 2003-12-05 | 2010-04-28 | F. Hoffmann-La Roche Ag | Carboxipeptidasa b recombinante y su purificacion. |
| AU2006291780B2 (en) * | 2005-09-14 | 2011-12-08 | F. Hoffmann-La Roche Ag | Cleavage of precursors of insulins by a variant of trypsin |
| JP4216875B2 (ja) * | 2006-09-29 | 2009-01-28 | 株式会社東芝 | メタノール応答性プロモーター、プロモーターと外来遺伝子を発現可能な様式で連結した融合遺伝子、ベクター、形質転換体、およびタンパク質の生産方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1341130C (fr) * | 1984-07-27 | 2000-10-31 | Adrianus Marinus Ledeboer | Utilisation d'oxydoreductases dans les compositions de blanchiment et/ou detergent et leur preparation par des micro-organismes obtenus par technique d'adn recombinant |
| US4855231A (en) * | 1984-10-30 | 1989-08-08 | Phillips Petroleum Company | Regulatory region for heterologous gene expression in yeast |
| US4882279A (en) * | 1985-10-25 | 1989-11-21 | Phillips Petroleum Company | Site selective genomic modification of yeast of the genus pichia |
| US4895800A (en) * | 1985-11-26 | 1990-01-23 | Phillips Petroleum Company | Yeast production of hepatitis B surface antigen |
| IL82935A0 (en) * | 1986-08-12 | 1987-12-20 | Phillips Petroleum Co | Secretion of heterologous proteins from yeast |
| IL90161A0 (en) * | 1988-05-13 | 1989-12-15 | Phillips Petroleum Co | Expression of hepatitis b s and pres2 proteins in methylotrophic yeasts |
-
1988
- 1988-06-24 US US07/211,007 patent/US5032516A/en not_active Expired - Lifetime
-
1989
- 1989-06-13 NZ NZ229534A patent/NZ229534A/en unknown
- 1989-06-13 ZA ZA894495A patent/ZA894495B/xx unknown
- 1989-06-14 CA CA000602769A patent/CA1306211C/fr not_active Expired - Lifetime
- 1989-06-19 MX MX1651889A patent/MX16518A/es unknown
- 1989-06-21 DD DD89329825A patent/DD284047A5/de unknown
- 1989-06-23 JP JP1162492A patent/JPH0773501B2/ja not_active Expired - Lifetime
- 1989-06-23 AU AU37002/89A patent/AU615078B2/en not_active Expired
- 1989-06-23 IE IE205589A patent/IE67039B1/en not_active IP Right Cessation
- 1989-06-23 KR KR1019890008823A patent/KR960010590B1/ko not_active Expired - Lifetime
- 1989-06-23 YU YU128789A patent/YU128789A/sh unknown
- 1989-06-23 PT PT90970A patent/PT90970A/pt not_active Application Discontinuation
- 1989-06-23 EP EP89111464A patent/EP0347928A3/fr not_active Withdrawn
- 1989-06-23 NO NO892634A patent/NO301285B1/no not_active IP Right Cessation
- 1989-06-23 PH PH38829A patent/PH27314A/en unknown
- 1989-06-23 HU HU893208A patent/HUT51673A/hu unknown
- 1989-06-23 CN CN89104253A patent/CN1039616A/zh active Pending
- 1989-06-23 DK DK198903131A patent/DK175822B1/da not_active IP Right Cessation
- 1989-06-26 FI FI893109A patent/FI104497B/fi active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| KR910001049A (ko) | 1991-01-30 |
| ZA894495B (en) | 1990-03-28 |
| KR960010590B1 (ko) | 1996-08-06 |
| EP0347928A3 (fr) | 1990-02-07 |
| HUT51673A (en) | 1990-05-28 |
| JPH0773501B2 (ja) | 1995-08-09 |
| DK313189A (da) | 1989-12-25 |
| NO892634L (no) | 1989-12-27 |
| IE67039B1 (en) | 1996-02-21 |
| FI893109L (fi) | 1989-12-25 |
| PT90970A (pt) | 1989-12-29 |
| IE892055L (en) | 1989-12-24 |
| DK175822B1 (da) | 2005-03-14 |
| CA1306211C (fr) | 1992-08-11 |
| JPH0253489A (ja) | 1990-02-22 |
| FI104497B (fi) | 2000-02-15 |
| DK313189D0 (da) | 1989-06-23 |
| NO301285B1 (no) | 1997-10-06 |
| CN1039616A (zh) | 1990-02-14 |
| MX16518A (es) | 1993-10-01 |
| EP0347928A2 (fr) | 1989-12-27 |
| YU128789A (sh) | 1992-07-20 |
| US5032516A (en) | 1991-07-16 |
| FI893109A0 (fi) | 1989-06-26 |
| AU615078B2 (en) | 1991-09-19 |
| NZ229534A (en) | 1991-04-26 |
| AU3700289A (en) | 1990-01-04 |
| PH27314A (en) | 1993-05-28 |
| NO892634D0 (no) | 1989-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RPI | Change in the person, name or address of the patentee (searches according to art. 11 and 12 extension act) | ||
| RPV | Change in the person, the name or the address of the representative (searches according to art. 11 and 12 extension act) | ||
| ASS | Change of applicant or owner |
Owner name: RESEARCH CORPORATION TECHNOLOGIES, INC Effective date: 19940503 |
|
| IF04 | In force in the year 2004 |
Expiry date: 20090622 |