DD284806A5 - Stabile oxapenem-3-carbonsaeuren und ihre verwendung als beta-lactamasehemmer - Google Patents

Stabile oxapenem-3-carbonsaeuren und ihre verwendung als beta-lactamasehemmer Download PDF

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Publication number
DD284806A5
DD284806A5 DD89333238A DD33323889A DD284806A5 DD 284806 A5 DD284806 A5 DD 284806A5 DD 89333238 A DD89333238 A DD 89333238A DD 33323889 A DD33323889 A DD 33323889A DD 284806 A5 DD284806 A5 DD 284806A5
Authority
DD
German Democratic Republic
Prior art keywords
oxapenem
oxo
tert
carboxylic acids
reaction
Prior art date
Application number
DD89333238A
Other languages
German (de)
English (en)
Inventor
Hans-Rudolf Pfaendler
Karl G Metzger
Rainer Endermann
Ingo Haller
Hanno Wild
Wolfgang Hartwig
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �����@������������������k�� filed Critical �����@������������������k��
Publication of DD284806A5 publication Critical patent/DD284806A5/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DD89333238A 1988-10-04 1989-10-02 Stabile oxapenem-3-carbonsaeuren und ihre verwendung als beta-lactamasehemmer DD284806A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3833693A DE3833693A1 (de) 1988-10-04 1988-10-04 Stabile oxapenem-3-carbonsaeuren und ihre verwendung als ss-lactamasehemmer

Publications (1)

Publication Number Publication Date
DD284806A5 true DD284806A5 (de) 1990-11-28

Family

ID=6364340

Family Applications (1)

Application Number Title Priority Date Filing Date
DD89333238A DD284806A5 (de) 1988-10-04 1989-10-02 Stabile oxapenem-3-carbonsaeuren und ihre verwendung als beta-lactamasehemmer

Country Status (20)

Country Link
US (1) US5108747A (da)
EP (1) EP0362622B1 (da)
JP (1) JP2654201B2 (da)
KR (1) KR900005977A (da)
CN (1) CN1041596A (da)
AT (1) ATE120369T1 (da)
AU (1) AU623932B2 (da)
CA (1) CA2000058A1 (da)
DD (1) DD284806A5 (da)
DE (2) DE3833693A1 (da)
DK (1) DK486589A (da)
ES (1) ES2071636T3 (da)
FI (1) FI894653A7 (da)
HU (1) HUT53650A (da)
IE (1) IE68344B1 (da)
IL (1) IL91813A0 (da)
NO (1) NO893727L (da)
NZ (1) NZ230827A (da)
PT (1) PT91873B (da)
ZA (1) ZA897505B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4027928A1 (de) * 1990-09-04 1992-03-05 Bayer Ag Neue 2-tert.substituierte methyl-oxapenem-3-carbonsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung
DE4142423A1 (de) * 1991-12-20 1993-06-24 Pfaendler Hans Rudolf ((ls)-hydroxyalkyl)oxapenem-3-carbonsaeuren und ihre verwendung als betalactamasehemmer
GB9421816D0 (en) * 1994-10-29 1994-12-14 Smithkline Beecham Plc Novel compounds
ES2310561T3 (es) 2000-10-19 2009-01-16 Amura Limited Composiciones farmaceuticas que contienen acidos oxapenem-3-carboxilicos.
GB2369358A (en) * 2000-10-19 2002-05-29 Amura Ltd Oxapenems and pharmaceutical compositions thereof
EP1199077A1 (en) * 2000-10-19 2002-04-24 Amura Limited Stable compositions of oxapenem-3-carboxylic acids by Co-lyophilisation with pharmaceutical carriers
GB0106428D0 (en) * 2001-03-15 2001-05-02 Amura Ltd Antibacterial composition

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2045236A (en) * 1979-03-26 1980-10-29 Hoechst Uk Ltd Oxapenem derivatives
DE3725375A1 (de) * 1987-07-31 1989-02-09 Bayer Ag Stabile oxapenem-3-carbonsaeuren

Also Published As

Publication number Publication date
CN1041596A (zh) 1990-04-25
FI894653A0 (fi) 1989-10-02
NZ230827A (en) 1991-05-28
IL91813A0 (en) 1990-06-10
AU623932B2 (en) 1992-05-28
HUT53650A (en) 1990-11-28
DK486589D0 (da) 1989-10-03
ZA897505B (en) 1990-07-25
FI894653L (fi) 1990-04-05
PT91873B (pt) 1995-09-12
IE893157L (en) 1990-04-04
JP2654201B2 (ja) 1997-09-17
US5108747A (en) 1992-04-28
DK486589A (da) 1990-04-05
CA2000058A1 (en) 1990-04-04
FI894653A7 (fi) 1990-04-05
EP0362622B1 (de) 1995-03-29
ES2071636T3 (es) 1995-07-01
KR900005977A (ko) 1990-05-07
NO893727D0 (no) 1989-09-19
EP0362622A1 (de) 1990-04-11
NO893727L (no) 1990-04-05
DE58909140D1 (de) 1995-05-04
IE68344B1 (en) 1996-06-12
PT91873A (pt) 1990-04-30
ATE120369T1 (de) 1995-04-15
JPH02145519A (ja) 1990-06-05
DE3833693A1 (de) 1990-04-05
AU4233589A (en) 1990-04-12

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