DD294254A5 - Verfahren zur herstellung von salzen des azelastins - Google Patents
Verfahren zur herstellung von salzen des azelastins Download PDFInfo
- Publication number
- DD294254A5 DD294254A5 DD90340395A DD34039590A DD294254A5 DD 294254 A5 DD294254 A5 DD 294254A5 DD 90340395 A DD90340395 A DD 90340395A DD 34039590 A DD34039590 A DD 34039590A DD 294254 A5 DD294254 A5 DD 294254A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- acid
- optionally
- azelastine
- salt
- salts
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cephalosporin Compounds (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3914859 | 1989-05-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD294254A5 true DD294254A5 (de) | 1991-09-26 |
Family
ID=6380164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD90340395A DD294254A5 (de) | 1989-05-05 | 1990-05-04 | Verfahren zur herstellung von salzen des azelastins |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US5086050A (fr) |
| EP (1) | EP0396069B1 (fr) |
| JP (1) | JPH02295987A (fr) |
| AT (1) | ATE107643T1 (fr) |
| AU (1) | AU622022B2 (fr) |
| CA (1) | CA2016089C (fr) |
| DD (1) | DD294254A5 (fr) |
| DE (2) | DE59006184D1 (fr) |
| DK (1) | DK0396069T3 (fr) |
| ES (1) | ES2055216T3 (fr) |
| FI (1) | FI902244A7 (fr) |
| HU (1) | HU206110B (fr) |
| IE (1) | IE63662B1 (fr) |
| NO (1) | NO901985L (fr) |
| NZ (1) | NZ233546A (fr) |
| PT (1) | PT93946B (fr) |
| YU (1) | YU86390A (fr) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5271946A (en) * | 1988-04-20 | 1993-12-21 | Asta Pharma Aktiengesellschaft | Controlled release azelastine-containing pharmaceutical compositions |
| JPH04198180A (ja) * | 1990-11-28 | 1992-07-17 | Eezai Kagaku Kk | ベンジルフタラゾン誘導体の製造方法 |
| US5296472A (en) * | 1991-12-05 | 1994-03-22 | Vyrex Corporation | Methods for delipidation of skin and cerumen removal |
| JP4138910B2 (ja) | 1997-07-02 | 2008-08-27 | 帝國製薬株式会社 | 経皮吸収性が良好で且つ皮膚刺激性の少ない塩酸アゼラスチン含有経皮製剤 |
| EP1032403B1 (fr) * | 1997-10-24 | 2012-05-02 | John P. Blass | Supplement nutritionnel pour personnes atteintes d'insuffisances du metabolisme cerebral |
| FI109332B (fi) | 1998-12-17 | 2002-07-15 | Orion Yhtymae Oyj | Toremifeenin liukoisia koostumuksia |
| FI982733L (fi) | 1998-12-17 | 2000-06-18 | Orion Yhtymae Oyj | Trifenyylietyleeniantiestrogeenien liukoisia koostumuksia |
| GB2389530B (en) * | 2002-06-14 | 2007-01-10 | Cipla Ltd | Pharmaceutical compositions |
| US7694694B2 (en) * | 2004-05-10 | 2010-04-13 | The Aerospace Corporation | Phase-change valve apparatuses |
| US20070020330A1 (en) * | 2004-11-24 | 2007-01-25 | Medpointe Healthcare Inc. | Compositions comprising azelastine and methods of use thereof |
| JP5607291B2 (ja) * | 2004-11-24 | 2014-10-15 | メダ ファーマシューティカルズ インコーポレイテッド | アゼラスチンを含む組成物およびその使用方法 |
| US8758816B2 (en) * | 2004-11-24 | 2014-06-24 | Meda Pharmaceuticals Inc. | Compositions comprising azelastine and methods of use thereof |
| HUE038800T2 (hu) | 2011-04-13 | 2018-11-28 | Codexis Inc | Biokatalitikus eljárás eszlikarbazepin és ennek analógjai elõállítására |
| US10966989B2 (en) | 2019-04-12 | 2021-04-06 | LA PharmaTech Inc. | Pharmaceutical compositions and methods for treating mental, behavioral, cognitive disorders |
| US11938139B2 (en) | 2019-04-12 | 2024-03-26 | LA PharmaTech Inc. | Pharmaceutical compositions and methods for anxiety, depression and other psychiatric disorders |
| US11389458B2 (en) | 2019-04-12 | 2022-07-19 | LA PharmaTech Inc. | Pharmaceutical compositions and methods for treating parkinson's and huntington's disease |
| US11318144B2 (en) | 2019-04-12 | 2022-05-03 | LA PharmaTech Inc. | Compositions and methods for treating Alzheimer's disease and Parkinson's disease |
| US11690849B2 (en) | 2019-04-12 | 2023-07-04 | LA PharmaTech Inc. | Method of treating dementia |
| US10639314B1 (en) | 2019-04-30 | 2020-05-05 | LA PharmaTech Inc. | Method of treating Alzheimer's disease |
| US11744833B2 (en) | 2019-04-12 | 2023-09-05 | LA PharmaTech Inc. | Pharmaceutical compositions and methods for treatment of insomnia |
| US10898493B2 (en) | 2019-04-12 | 2021-01-26 | LA PharmaTech Inc. | Pharmaceutical compositions and methods for psychiatric symptoms of patients with Alzheimer's disease |
| US11351179B1 (en) | 2021-08-05 | 2022-06-07 | LA PharmaTech Inc. | Pharmaceutical compositions and methods for treatment of psychiatric disorders |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH572914A5 (fr) * | 1971-01-22 | 1976-02-27 | Asta Werke Ag Chem Fab | |
| US3813384A (en) * | 1972-01-17 | 1974-05-28 | Asta Werke Ag Chem Fab | Basically substituted benzyl phthalazone derivatives,acid salts thereof and process for the production thereof |
| EP0174464B1 (fr) * | 1984-09-14 | 1990-01-03 | ASTA Pharma AG | Benzyl-phtalazinones substitués |
| ES2031813T3 (es) * | 1985-11-11 | 1993-01-01 | Asta Pharma Ag | Procedimiento para la preparacion de derivados de 4-bencil-1-(2h)-ftalazinona. |
| JPH0667844B2 (ja) * | 1987-03-06 | 1994-08-31 | エーザイ株式会社 | 虚血性心疾患の治療・予防剤 |
| EP0289939A1 (fr) * | 1987-05-08 | 1988-11-09 | ASTA Pharma AG | Dérivés du 4-benzyl-1-(2H)-phtalazinone avec un radical acide aminé |
| ATE106883T1 (de) * | 1987-11-13 | 1994-06-15 | Asta Medica Ag | Azelastin-embonat, verfahren zu seiner herstellung und pharmazeutische zubereitungen, die als wirkstoff azelastin-embonat enthalten. |
| US5232919A (en) * | 1987-11-13 | 1993-08-03 | Asta Pharma Aktiengesellschaft | Azelastine embonate and compositions which contain it |
| AU609210B2 (en) * | 1987-11-13 | 1991-04-26 | Viatris Gmbh & Co. Kg | Azelastine embonate, processes for its preparation and pharmaceutical formulations which contain azelastine embonate as active substance |
| JP2794021B2 (ja) * | 1988-11-02 | 1998-09-03 | エーザイ株式会社 | アゼラスチン或いはその塩類含有経皮適用製剤 |
-
1990
- 1990-04-28 DK DK90108172.9T patent/DK0396069T3/da active
- 1990-04-28 DE DE59006184T patent/DE59006184D1/de not_active Expired - Lifetime
- 1990-04-28 DE DE4013696A patent/DE4013696A1/de not_active Withdrawn
- 1990-04-28 AT AT90108172T patent/ATE107643T1/de not_active IP Right Cessation
- 1990-04-28 ES ES90108172T patent/ES2055216T3/es not_active Expired - Lifetime
- 1990-04-28 EP EP90108172A patent/EP0396069B1/fr not_active Expired - Lifetime
- 1990-05-03 NZ NZ233546A patent/NZ233546A/xx unknown
- 1990-05-03 PT PT93946A patent/PT93946B/pt not_active IP Right Cessation
- 1990-05-04 NO NO90901985A patent/NO901985L/no unknown
- 1990-05-04 HU HU902678A patent/HU206110B/hu unknown
- 1990-05-04 AU AU54736/90A patent/AU622022B2/en not_active Ceased
- 1990-05-04 YU YU00863/90A patent/YU86390A/xx unknown
- 1990-05-04 IE IE163990A patent/IE63662B1/en not_active IP Right Cessation
- 1990-05-04 DD DD90340395A patent/DD294254A5/de not_active IP Right Cessation
- 1990-05-04 CA CA002016089A patent/CA2016089C/fr not_active Expired - Lifetime
- 1990-05-04 FI FI902244A patent/FI902244A7/fi not_active IP Right Cessation
- 1990-05-07 JP JP2115947A patent/JPH02295987A/ja active Pending
-
1991
- 1991-02-08 US US07/652,986 patent/US5086050A/en not_active Expired - Lifetime
-
1996
- 1996-08-02 US US08/691,415 patent/US5859003A/en not_active Expired - Lifetime
-
1998
- 1998-07-28 US US09/123,431 patent/US5998403A/en not_active Expired - Fee Related
- 1998-08-20 US US09/136,971 patent/US6017909A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IE63662B1 (en) | 1995-05-31 |
| CA2016089C (fr) | 1998-12-01 |
| YU86390A (en) | 1992-05-28 |
| EP0396069A1 (fr) | 1990-11-07 |
| US5998403A (en) | 1999-12-07 |
| US6017909A (en) | 2000-01-25 |
| JPH02295987A (ja) | 1990-12-06 |
| ATE107643T1 (de) | 1994-07-15 |
| HUT53901A (en) | 1990-12-28 |
| DE59006184D1 (de) | 1994-07-28 |
| DE4013696A1 (de) | 1990-11-08 |
| NO901985L (no) | 1990-11-06 |
| ES2055216T3 (es) | 1994-08-16 |
| CA2016089A1 (fr) | 1990-11-05 |
| AU622022B2 (en) | 1992-03-26 |
| PT93946A (pt) | 1991-01-08 |
| AU5473690A (en) | 1990-11-08 |
| US5086050A (en) | 1992-02-04 |
| FI902244A0 (fi) | 1990-05-04 |
| NO901985D0 (no) | 1990-05-04 |
| HU902678D0 (en) | 1990-09-28 |
| HU206110B (en) | 1992-08-28 |
| PT93946B (pt) | 1996-11-29 |
| EP0396069B1 (fr) | 1994-06-22 |
| US5859003A (en) | 1999-01-12 |
| IE901639L (en) | 1990-11-05 |
| NZ233546A (en) | 1991-09-25 |
| DK0396069T3 (da) | 1994-07-25 |
| FI902244A7 (fi) | 1990-11-06 |
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| ENJ | Ceased due to non-payment of renewal fee |