DD296843A5 - Monoklonale antikoerper zur indukzierung von tobranz - Google Patents

Monoklonale antikoerper zur indukzierung von tobranz Download PDF

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Publication number
DD296843A5
DD296843A5 DD90341218A DD34121890A DD296843A5 DD 296843 A5 DD296843 A5 DD 296843A5 DD 90341218 A DD90341218 A DD 90341218A DD 34121890 A DD34121890 A DD 34121890A DD 296843 A5 DD296843 A5 DD 296843A5
Authority
DD
German Democratic Republic
Prior art keywords
exhaustive
antibody
monoclonal
tolerance
antigen
Prior art date
Application number
DD90341218A
Other languages
German (de)
English (en)
Inventor
Stephen P Cobbold
Herman Waldmann
Original Assignee
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Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �������k��������@����k��, Kk filed Critical �������k��������@����k��
Publication of DD296843A5 publication Critical patent/DD296843A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2815—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DD90341218A 1989-05-31 1990-05-31 Monoklonale antikoerper zur indukzierung von tobranz DD296843A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898912497A GB8912497D0 (en) 1989-05-31 1989-05-31 Monoclonal antibodies

Publications (1)

Publication Number Publication Date
DD296843A5 true DD296843A5 (de) 1991-12-19

Family

ID=10657649

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90341218A DD296843A5 (de) 1989-05-31 1990-05-31 Monoklonale antikoerper zur indukzierung von tobranz

Country Status (19)

Country Link
EP (1) EP0474691B1 (ko)
JP (1) JP2763197B2 (ko)
KR (1) KR0183029B1 (ko)
AT (1) ATE145246T1 (ko)
AU (1) AU657255B2 (ko)
CA (1) CA2055615C (ko)
DD (1) DD296843A5 (ko)
DE (1) DE69029134T2 (ko)
DK (1) DK0474691T3 (ko)
ES (1) ES2096588T3 (ko)
GB (1) GB8912497D0 (ko)
HU (1) HUT61341A (ko)
IE (1) IE80735B1 (ko)
IL (1) IL94566A0 (ko)
MY (1) MY135673A (ko)
NZ (1) NZ233889A (ko)
PT (1) PT94214B (ko)
WO (1) WO1990015152A1 (ko)
ZA (1) ZA904174B (ko)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9100741D0 (en) * 1991-01-14 1991-02-27 Univ London Treatment of disease
US6136310A (en) * 1991-07-25 2000-10-24 Idec Pharmaceuticals Corporation Recombinant anti-CD4 antibodies for human therapy
AU687755B2 (en) * 1992-08-21 1998-03-05 Genentech Inc. Method for treating an LFA-1-mediated disorder
US6270766B1 (en) 1992-10-08 2001-08-07 The Kennedy Institute Of Rheumatology Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease
CA2221350A1 (en) * 1995-05-18 1996-11-21 Ortho Pharmaceutical Corporation Induction of immunological tolerance by the use of non-depleting anti-cd4 antibodies
EP1212422B1 (en) 1999-08-24 2007-02-21 Medarex, Inc. Human ctla-4 antibodies and their uses
US7011952B2 (en) 2000-02-22 2006-03-14 University Of Iowa Research Foundation Diagnostics and therapeutics for macular degeneration-related disorders
JP4764590B2 (ja) 2000-04-29 2011-09-07 ユニバーシティー オブ アイオワ リサーチ ファウンデーション 黄班変性関連疾患の診断および治療
EP1395284B1 (en) * 2001-06-14 2010-12-08 Isis Innovation Limited Non-depleting anti-CD4 antibody TRX1 and its uses
US7541443B2 (en) 2001-06-14 2009-06-02 Tolerrx, Inc. Anti-CD4 antibodies
EP1460088A1 (en) 2003-03-21 2004-09-22 Biotest AG Humanized anti-CD4 antibody with immunosuppressive properties
GB0314461D0 (en) * 2003-06-20 2003-07-23 Isis Innovation Suppression of transplant rejection
CA2570849A1 (en) * 2004-06-22 2006-01-05 Tolerrx, Inc. Optimized dosing with anti-cd4 antibodies for tolerance induction in primates
EP2260057B1 (en) 2008-03-13 2016-11-23 Biotest AG Anti-CD4 antibody dosage regimen for treating autoimmune disease
EP2265643B1 (en) 2008-03-13 2016-10-19 Biotest AG Dosing regimen for treating psoriasis and rheumatoid arthritis
RU2540013C2 (ru) 2008-03-13 2015-01-27 Биотест Аг Средство для лечения заболевания
WO2009149382A2 (en) * 2008-06-06 2009-12-10 Baylor Research Institute Anti-cd8 antibodies block priming of cytotoxic effectors and lead to generation of regulatory cd8+t cells
WO2010009129A2 (en) * 2008-07-15 2010-01-21 Genentech, Inc. Methods of treating autoimmune diseases using cd4 antibodies
GB0920944D0 (en) 2009-11-30 2010-01-13 Biotest Ag Agents for treating disease
CN120569191A (zh) 2022-11-23 2025-08-29 乔治亚大学研究基金公司 用于增加免疫应答的组合物及其使用方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8608068D0 (en) * 1986-04-02 1986-05-08 Cobbold S P Monoclonal antibodies

Also Published As

Publication number Publication date
CA2055615A1 (en) 1990-12-13
ZA904174B (en) 1992-02-26
AU5725890A (en) 1991-01-07
WO1990015152A1 (en) 1990-12-13
IE901949L (en) 1990-11-30
GB8912497D0 (en) 1989-07-19
JPH04505919A (ja) 1992-10-15
DK0474691T3 (da) 1996-12-02
PT94214B (pt) 1997-03-31
DE69029134D1 (de) 1996-12-19
JP2763197B2 (ja) 1998-06-11
NZ233889A (en) 1997-06-24
IE80735B1 (en) 1998-12-30
PT94214A (pt) 1991-02-08
KR0183029B1 (ko) 1999-04-01
AU657255B2 (en) 1995-03-09
EP0474691B1 (en) 1996-11-13
ES2096588T3 (es) 1997-03-16
MY135673A (en) 2008-06-30
DE69029134T2 (de) 1997-03-06
EP0474691A1 (en) 1992-03-18
HU905134D0 (en) 1992-02-28
HUT61341A (en) 1992-12-28
IL94566A0 (en) 1991-03-10
ATE145246T1 (de) 1996-11-15
CA2055615C (en) 2001-07-17

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