DD299425A5 - Neue 4,4-disubstituierte piperidin-derivate und verfahren zu ihrer herstellung - Google Patents

Neue 4,4-disubstituierte piperidin-derivate und verfahren zu ihrer herstellung Download PDF

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Publication number
DD299425A5
DD299425A5 DD90343364A DD34336490A DD299425A5 DD 299425 A5 DD299425 A5 DD 299425A5 DD 90343364 A DD90343364 A DD 90343364A DD 34336490 A DD34336490 A DD 34336490A DD 299425 A5 DD299425 A5 DD 299425A5
Authority
DD
German Democratic Republic
Prior art keywords
general formula
meaning
group
alkyl
hydrogen
Prior art date
Application number
DD90343364A
Other languages
German (de)
English (en)
Inventor
Edit Toth
Jozsef Toerley
Sandor Goeroeg
Laszlo Szporny
Bela Kiss
Eva Palosi
Dora Groo
Istvan Laszlovszky
Erzsebet Lapis
Ferenc Auth
Laszlo Gaal
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU894094A external-priority patent/HU204276B/hu
Application filed by �������@������@����������@����@��Kk�� filed Critical �������@������@����������@����@��Kk��
Publication of DD299425A5 publication Critical patent/DD299425A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DD90343364A 1989-08-10 1990-08-09 Neue 4,4-disubstituierte piperidin-derivate und verfahren zu ihrer herstellung DD299425A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU894094A HU204276B (en) 1989-08-10 1989-08-10 Process for producing new 1-oxa-2-oxo-4-methylen-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
HU323390 1990-05-29

Publications (1)

Publication Number Publication Date
DD299425A5 true DD299425A5 (de) 1992-04-16

Family

ID=26317611

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90343364A DD299425A5 (de) 1989-08-10 1990-08-09 Neue 4,4-disubstituierte piperidin-derivate und verfahren zu ihrer herstellung

Country Status (12)

Country Link
US (1) US5118693A (fr)
EP (1) EP0412822B1 (fr)
JP (1) JPH0377866A (fr)
KR (1) KR940003491B1 (fr)
AT (1) ATE103896T1 (fr)
AU (1) AU624261B2 (fr)
DD (1) DD299425A5 (fr)
DE (1) DE69007900T2 (fr)
DK (1) DK0412822T3 (fr)
ES (1) ES2063282T3 (fr)
IL (1) IL95323A (fr)
NZ (1) NZ234847A (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU204530B (en) * 1989-08-10 1992-01-28 Richter Gedeon Vegyeszet Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
US5336675A (en) * 1991-05-14 1994-08-09 Ernir Snorrason Method of treating mania in humans
SE9604786D0 (sv) 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
US6974825B1 (en) 1996-12-20 2005-12-13 Astrazeneca Canada Inc. Compounds with analgesic effect
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
US6656953B2 (en) 2000-12-06 2003-12-02 Sepracor Inc. 4,4-Disubstituted piperidines, and methods of use thereof
SE0101771D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101773D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101770D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101769D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2838518A (en) * 1953-12-24 1958-06-10 Degussa Ethynyl piperidyl carbamic acid esters
DE1137438B (de) * 1955-08-27 1962-10-04 Degussa Verfahren zur Herstellung von sedativ bzw. hypnotisch wirksamen Carbaminsaeureestern
HU204529B (en) * 1989-08-10 1992-01-28 Richter Gedeon Vegyeszet Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DE69007900T2 (de) 1994-07-21
JPH0377866A (ja) 1991-04-03
ES2063282T3 (es) 1995-01-01
KR940003491B1 (ko) 1994-04-23
KR910004563A (ko) 1991-03-28
IL95323A0 (en) 1991-06-30
NZ234847A (en) 1994-05-26
DE69007900D1 (de) 1994-05-11
DK0412822T3 (da) 1994-05-16
US5118693A (en) 1992-06-02
IL95323A (en) 1994-06-24
EP0412822A3 (en) 1991-11-27
AU624261B2 (en) 1992-06-04
AU6080690A (en) 1991-02-14
EP0412822B1 (fr) 1994-04-06
ATE103896T1 (de) 1994-04-15
EP0412822A2 (fr) 1991-02-13

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