DE3689330T2 - Nichtionische polyolkontrastmittel aus ionischen kontrastmitteln. - Google Patents

Nichtionische polyolkontrastmittel aus ionischen kontrastmitteln.

Info

Publication number
DE3689330T2
DE3689330T2 DE3689330T DE3689330T DE3689330T2 DE 3689330 T2 DE3689330 T2 DE 3689330T2 DE 3689330 T DE3689330 T DE 3689330T DE 3689330 T DE3689330 T DE 3689330T DE 3689330 T2 DE3689330 T2 DE 3689330T2
Authority
DE
Germany
Prior art keywords
acid
isophthalamide
mol
usually
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3689330T
Other languages
German (de)
English (en)
Other versions
DE3689330D1 (de
Inventor
Ramachandran Ranganathan
Milos Sovak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cook Imaging Corp
Original Assignee
Cook Imaging Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cook Imaging Corp filed Critical Cook Imaging Corp
Application granted granted Critical
Publication of DE3689330D1 publication Critical patent/DE3689330D1/de
Publication of DE3689330T2 publication Critical patent/DE3689330T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DE3689330T 1985-08-09 1986-08-01 Nichtionische polyolkontrastmittel aus ionischen kontrastmitteln. Expired - Lifetime DE3689330T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76427485A 1985-08-09 1985-08-09
PCT/US1986/001590 WO1987000757A1 (en) 1985-08-09 1986-08-01 Non-ionic polyol contrast media from ionic contrast media

Publications (2)

Publication Number Publication Date
DE3689330D1 DE3689330D1 (de) 1994-01-05
DE3689330T2 true DE3689330T2 (de) 1994-05-19

Family

ID=25070222

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3689330T Expired - Lifetime DE3689330T2 (de) 1985-08-09 1986-08-01 Nichtionische polyolkontrastmittel aus ionischen kontrastmitteln.

Country Status (9)

Country Link
EP (1) EP0233249B1 (da)
JP (1) JPH0813794B2 (da)
AU (3) AU600672B2 (da)
CA (1) CA1339666C (da)
DE (1) DE3689330T2 (da)
DK (1) DK174745B1 (da)
HK (1) HK1003564A1 (da)
NO (1) NO178106C (da)
WO (1) WO1987000757A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4109169A1 (de) * 1991-03-20 1992-09-24 Koehler Chemie Dr Franz Wasserloesliche nicht ionische roentgenkontrastmittel sowie mittel und verfahren zu ihrer herstellung
US5840967A (en) 1996-08-29 1998-11-24 Nycomed Imaging As Process for the preparation of contrast agents
GB9618055D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
WO2002051301A2 (en) 2000-11-10 2002-07-04 Wm. Marsh Rice University Fullerene (c60)-based x-ray contrast agent for diagnostic imaging
FR2899581B1 (fr) * 2006-04-07 2008-06-27 Guerbet Sa Procede d'atomisation du ioxilan
US20110256068A1 (en) 2009-01-09 2011-10-20 Wistand Lars-Goeran Contrast media compositions
PT108524B (pt) 2015-06-02 2017-12-15 Hovione Farmaciência S A Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3701771A (en) * 1969-06-27 1972-10-31 Nyegaard & Co As N-(2,4,6-triiodobenzoyl)-sugar amines
BE788054A (fr) * 1971-08-26 1973-02-26 Bracco Ind Chimica Spa Nouvel agent de contraste radiographique et procede pour le preparer
CH608189A5 (da) * 1974-12-13 1978-12-29 Savac Ag
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
ES8200082A1 (es) * 1978-07-04 1980-12-16 Nyegaard & Co As Procedimiento para esterilizar un agente de contraste de ra-yos x de m-carboxamido-o-yodo-n-(b-hidroxialcohil)-anilina.
DE2909439A1 (de) * 1979-03-08 1980-09-18 Schering Ag Neue nichtionische roentgenkontrastmittel
IT1193211B (it) * 1979-08-09 1988-06-15 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
DE3150916A1 (de) * 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel"
US4396598A (en) * 1982-01-11 1983-08-02 Mallinckrodt, Inc. Triiodoisophthalamide X-ray contrast agent
DK162045C (da) * 1982-10-01 1992-02-10 Nyegaard & Co As Trijodbenzenderivater, fremgangsmaade til fremstilling deraf og radiologiske praeparater indeholdende saadanne forbindelser

Also Published As

Publication number Publication date
DK174745B1 (da) 2003-10-13
DE3689330D1 (de) 1994-01-05
CA1339666C (en) 1998-02-10
DK178587D0 (da) 1987-04-08
NO178106C (no) 1996-01-24
NO178106B (no) 1995-10-16
AU6197486A (en) 1987-03-05
AU6686690A (en) 1991-06-13
EP0233249A1 (en) 1987-08-26
AU600672B2 (en) 1990-08-23
AU673286B2 (en) 1996-10-31
JPH0813794B2 (ja) 1996-02-14
EP0233249B1 (en) 1993-11-24
WO1987000757A1 (en) 1987-02-12
JPS63500522A (ja) 1988-02-25
AU650432B2 (en) 1994-06-23
NO871474D0 (no) 1987-04-08
EP0233249A4 (en) 1988-10-06
AU7415594A (en) 1995-01-05
DK178587A (da) 1987-04-08
HK1003564A1 (en) 1998-10-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition