DE69519393D1 - Zusammensetzung und verfahren zur förderung von transdermaler elektrotransport-darreichung - Google Patents

Zusammensetzung und verfahren zur förderung von transdermaler elektrotransport-darreichung

Info

Publication number
DE69519393D1
DE69519393D1 DE69519393T DE69519393T DE69519393D1 DE 69519393 D1 DE69519393 D1 DE 69519393D1 DE 69519393 T DE69519393 T DE 69519393T DE 69519393 T DE69519393 T DE 69519393T DE 69519393 D1 DE69519393 D1 DE 69519393D1
Authority
DE
Germany
Prior art keywords
electrotransport
agent
composition
electric transport
transport delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69519393T
Other languages
English (en)
Other versions
DE69519393T2 (de
Inventor
J Richard Gyory
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DE69519393D1 publication Critical patent/DE69519393D1/de
Publication of DE69519393T2 publication Critical patent/DE69519393T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69519393T 1994-07-13 1995-06-29 Zusammensetzung und verfahren zur förderung von transdermaler elektrotransport-darreichung Expired - Lifetime DE69519393T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27461994A 1994-07-13 1994-07-13
PCT/US1995/008384 WO1996002232A1 (en) 1994-07-13 1995-06-29 Composition and method for enhancing transdermal electrotransport agent delivery

Publications (2)

Publication Number Publication Date
DE69519393D1 true DE69519393D1 (de) 2000-12-14
DE69519393T2 DE69519393T2 (de) 2001-04-26

Family

ID=23048961

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69519393T Expired - Lifetime DE69519393T2 (de) 1994-07-13 1995-06-29 Zusammensetzung und verfahren zur förderung von transdermaler elektrotransport-darreichung

Country Status (7)

Country Link
US (1) US5668170A (de)
EP (1) EP0804155B1 (de)
JP (2) JP4090072B2 (de)
AT (1) ATE197396T1 (de)
DE (1) DE69519393T2 (de)
ES (1) ES2153485T3 (de)
WO (1) WO1996002232A1 (de)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6956032B1 (en) 1986-04-18 2005-10-18 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
EP0793517B1 (de) * 1994-11-17 1999-09-08 Alza Corporation Vorrichtung zur erhöhung der wirkstoffsverabreichung durch elektrotransport
US6032073A (en) * 1995-04-07 2000-02-29 Novartis Ag Iontophoretic transdermal system for the administration of at least two substances
US5985316A (en) * 1995-04-28 1999-11-16 Alza Corporation Composition and method of enhancing electrotransport agent delivery
US6385487B1 (en) 1996-05-08 2002-05-07 Biophoretic Therapeutic Systems, Llc Methods for electrokinetic delivery of medicaments
US5676648A (en) 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use
ATE250957T1 (de) * 1996-06-12 2003-10-15 Alza Corp Verbesserte elektrophoretische verabreichung von therapeutischen wirkstoffen mit polybasischen anionischen gegenionen
US6004577A (en) * 1997-08-12 1999-12-21 Murdock; Thomas O. Enhanced electrotransport of therapeutic agents having polybasic anionic counter ions
US6775569B2 (en) * 1997-11-05 2004-08-10 Hisamitsu Pharmaceutical Co., Inc. Electroporation device for in vivo delivery of therapeutic agents
USRE37796E1 (en) 1997-12-16 2002-07-23 Biophoretic Therapeutic Systems, Llc Methods for iontophoretic delivery of antiviral agents
US6374136B1 (en) * 1997-12-22 2002-04-16 Alza Corporation Anhydrous drug reservoir for electrolytic transdermal delivery device
BR9909801A (pt) * 1998-04-21 2002-01-22 Infectio Recherche Inc Formulações para a prevenção ou o tratamento de doenças que afetam mucosas ou pele, ou para evitar gravidez, e um aplicador para a liberação de formulações tópicas para as cavidades mucosas
US6148231A (en) 1998-09-15 2000-11-14 Biophoretic Therapeutic Systems, Llc Iontophoretic drug delivery electrodes and method
US7919109B2 (en) 1999-02-08 2011-04-05 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
US7258869B1 (en) 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
US6477410B1 (en) 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US6792306B2 (en) 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US7127285B2 (en) 1999-03-12 2006-10-24 Transport Pharmaceuticals Inc. Systems and methods for electrokinetic delivery of a substance
US6347246B1 (en) 2000-02-03 2002-02-12 Axelgaard Manufacturing Company, Ltd. Electrotransport adhesive for iontophoresis device
US6522918B1 (en) 2000-02-09 2003-02-18 William E. Crisp Electrolytic device
EP1307182B1 (de) * 2000-08-01 2005-03-30 Sanofi-Aventis Pharmazeutische zusammensetzung zur verabreichung von beflotaxone
US7465295B2 (en) * 2000-10-20 2008-12-16 Bergeron Michel G Applicator for the delivery of topical formulations into mucosal cavities
US7137975B2 (en) * 2001-02-13 2006-11-21 Aciont, Inc. Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent
EE200400090A (et) * 2001-10-31 2004-10-15 R&R Ventures Incorporation Ionoforeesiseade
US7099713B2 (en) 2002-06-28 2006-08-29 Battelle Memorial Institute Skin conduction and transport systems
US7458982B2 (en) * 2002-10-04 2008-12-02 Photokinetix, Inc. Photokinetic delivery of biologically active substances using pulsed incoherent light
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
DE602004017720D1 (de) * 2003-06-02 2008-12-24 Power Paper Ltd Bausatz, vorrichtung und verfahren zur gesteuerten abgabe eines oxidationsmittels in die haut
JP4728631B2 (ja) * 2004-11-30 2011-07-20 Tti・エルビュー株式会社 イオントフォレーシス装置
US7590444B2 (en) * 2004-12-09 2009-09-15 Tti Ellebeau, Inc. Iontophoresis device
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
JP4731931B2 (ja) * 2005-02-03 2011-07-27 Tti・エルビュー株式会社 イオントフォレーシス装置
JP4793806B2 (ja) * 2005-03-22 2011-10-12 Tti・エルビュー株式会社 イオントフォレーシス装置
US8386030B2 (en) 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US20070088331A1 (en) * 2005-08-18 2007-04-19 Transcutaneous Technologies Inc. Method and apparatus for managing active agent usage, and active agent injecting device
KR20080047600A (ko) 2005-09-15 2008-05-29 티티아이 엘뷰 가부시키가이샤 로드형 이온토포레시스 장치
WO2007041118A1 (en) 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Iontophoretic device and method of delivery of active agents to biological interface
WO2007041526A2 (en) * 2005-09-30 2007-04-12 Transcutaneous Technologies Inc. Iontophoresis apparatus and method to deliver antibiotics to biological interfaces
WO2007079193A2 (en) 2005-12-30 2007-07-12 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
KR101106510B1 (ko) 2006-05-30 2012-01-20 인타르시아 세라퓨틱스 인코포레이티드 투피스, 내부채널 삼투압 전달 시스템 유동 조절기
EP2359808B1 (de) 2006-08-09 2013-05-22 Intarcia Therapeutics, Inc Osmotisches Verabreichungssystem mit Kolbenanordnung
WO2008087803A1 (ja) * 2007-01-16 2008-07-24 Hokkaido University 抗酸化成分を封入したイオントフォレーシス用リポソーム製剤
WO2008133908A2 (en) 2007-04-23 2008-11-06 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
KR101674904B1 (ko) 2009-02-26 2016-11-10 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 중재형 약물전달 시스템과 그 방법
RU2547990C2 (ru) 2009-09-28 2015-04-10 Интарсия Терапьютикс, Инк. Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства
US20110087153A1 (en) * 2009-10-13 2011-04-14 Angelov Angel S Transdermal Methods And Systems For The Delivery Of Rizatriptan
US9237961B2 (en) * 2010-04-23 2016-01-19 Medtronic Vascular, Inc. Stent delivery system for detecting wall apposition of the stent during deployment
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9468682B2 (en) 2013-04-05 2016-10-18 Joint-stock company “High Tech” Compositions and methods for enhancing penetration of biologically active substances into tissues or organs
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
RU2730996C2 (ru) 2015-06-03 2020-08-26 Интарсия Терапьютикс, Инк. Системы установки и извлечения имплантата
KR102574993B1 (ko) 2016-05-16 2023-09-06 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
JP7286542B2 (ja) 2017-01-03 2023-06-05 インターシア セラピューティクス,インコーポレイティド Glp-1受容体アゴニストの持続的投与及び薬物の同時投与を含む方法
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4153689A (en) * 1975-06-13 1979-05-08 Takeda Chemical Industries, Ltd. Stable insulin preparation for nasal administration
US4690683A (en) * 1985-07-02 1987-09-01 Rutgers, The State University Of New Jersey Transdermal varapamil delivery device
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4992477A (en) * 1988-04-04 1991-02-12 Warner-Lambert Company Skin moisturizing composition and method of preparing same
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
US5023085A (en) * 1989-11-29 1991-06-11 Pfizer Inc. Transdermal flux enhancers in combination with iontophoresis in topical administration of pharmaceuticals
NZ237489A (en) * 1990-04-18 1995-07-26 Alza Corp Device for electrotransport and reservoir therefor containing a fatty acid as permeation enhancing agent
US5336692A (en) * 1990-06-28 1994-08-09 Medicis Pharmaceutical Corporation Ointment base and method of use
EP0552879B1 (de) * 1992-01-21 1998-08-19 Macrochem Corporation Iontophoretische verbesserte Verabreichung von Medikamenten
JPH0616538A (ja) * 1992-07-03 1994-01-25 Japan Tobacco Inc イオントフォレーゼのための薬物吸収用液組成物

Also Published As

Publication number Publication date
DE69519393T2 (de) 2001-04-26
EP0804155A1 (de) 1997-11-05
WO1996002232A1 (en) 1996-02-01
JP4090072B2 (ja) 2008-05-28
ES2153485T3 (es) 2001-03-01
EP0804155B1 (de) 2000-11-08
JP2007314562A (ja) 2007-12-06
JPH10503184A (ja) 1998-03-24
US5668170A (en) 1997-09-16
ATE197396T1 (de) 2000-11-11

Similar Documents

Publication Publication Date Title
DE69519393D1 (de) Zusammensetzung und verfahren zur förderung von transdermaler elektrotransport-darreichung
ATE369150T1 (de) Zusammensetzungen, vorrichtung und verfahren zur elektrotransport-wirkstoffabgabe
DE60129965D1 (de) Lagerstabile iontophorese reservoirelektrode sowie iontophoretisches system
EP0325613A4 (de) Eindringungserhöhende mittel zur transdermalen verabreichung systemischer mittel.
ATE258068T1 (de) Zusammensetzung, vorrichtung und verfahren zur verbesserten elektrotransport-wirkstoffabgabe
DE69531074D1 (de) Gerät zur Abgabe von Defibrillationsschocks mit verbesserter Wirkungskraft
ATE223745T1 (de) Zusammensetzung zur verbesserten elektroübertragunslieferung von wirkstoff
DE69115360D1 (de) Verfahren und Gerät zur Pflege der Aktivität einer Enzymelektrode
IT8536156V0 (it) Garze cosmetiche
DE69730973D1 (de) Vorrichtung zur verbesserung der transdermalen abnahme von körperflüssigkeiten
ATE114486T1 (de) Verfahren und vorrichtung zur iontophoretischen abgabe von medikamenten.
DE68910520D1 (de) Verfahren zur Verminderung von Hautirritationen bei Anwendung von durchdringungsverstärkenden Arzneimittelzusammensetzungen.
PT96021A (pt) Metodo de tratamento de doencas utilizando potenciadores de fluxo transdermico tais como acido e 1-dodecilazacicloheptan-2-ona em combinacao com iontoforese na administracao topica de agentes farmaceuticos
AU8132787A (en) Penetration enhancers for transdermal delivery of systemic agents
EP0138589A3 (en) Bone cement applicator
EG17345A (en) Compositions and methods of enhancing transdermal and transmembrane penetration of topical and systemic agents
DE69623155D1 (de) Verfahren zur transdermalen Verabreichung von Medikamenten
EP0416034A4 (en) Penetration enhancers for transdermal delivery of systemic agent
DE69611971D1 (de) Vorrichtung und Verfahren zur Graphitisierung von Elektrodenkörpern aus Kohlenstoff in Längsrichtung
FI895169A0 (fi) Pappersbestrykning.
ATE201997T1 (de) Zusammensetzung und verfahren zur verstärkung von elektrotransport-wirkstoffzufuhr
DE3778998D1 (de) Selektive elektrode fuer natrium-ionen und verfahren fuer deren anwendung.
DE3271605D1 (en) Improvements in or relating to electrotherapeutic apparatus
CA2190370A1 (en) Composition and method for enhancing transdermal electrotransport agent delivery
DE3678099D1 (de) Verfahren und vorrichtung zur verbesserung der eisenverluste von blechen aus elektromagnetischem stahl oder aus amorphem material.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KUDLEK & GRUNERT PATENTANWAELTE PARTNERSCHAFT, 803