ATE200517T1 - Nicht selbstinaktivierende retrovirale vektoren mit gezielter expression - Google Patents

Nicht selbstinaktivierende retrovirale vektoren mit gezielter expression

Info

Publication number
ATE200517T1
ATE200517T1 AT95931969T AT95931969T ATE200517T1 AT E200517 T1 ATE200517 T1 AT E200517T1 AT 95931969 T AT95931969 T AT 95931969T AT 95931969 T AT95931969 T AT 95931969T AT E200517 T1 ATE200517 T1 AT E200517T1
Authority
AT
Austria
Prior art keywords
region
self
retroviral vectors
targeted expression
inactivate
Prior art date
Application number
AT95931969T
Other languages
English (en)
Inventor
Walter Henry Guenzburg
Robert Michael Saller
Original Assignee
Gsf Forschungszentrum Umwelt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gsf Forschungszentrum Umwelt filed Critical Gsf Forschungszentrum Umwelt
Application granted granted Critical
Publication of ATE200517T1 publication Critical patent/ATE200517T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Ceramic Products (AREA)
  • Traffic Control Systems (AREA)
  • Navigation (AREA)
  • Molds, Cores, And Manufacturing Methods Thereof (AREA)
  • Road Signs Or Road Markings (AREA)
  • Optical Radar Systems And Details Thereof (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
AT95931969T 1994-09-02 1995-09-01 Nicht selbstinaktivierende retrovirale vektoren mit gezielter expression ATE200517T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK101794 1994-09-02
PCT/EP1995/003445 WO1996007748A1 (en) 1994-09-02 1995-09-01 Non self-inactivating, expression targeted retroviral vectors

Publications (1)

Publication Number Publication Date
ATE200517T1 true ATE200517T1 (de) 2001-04-15

Family

ID=8100062

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95931969T ATE200517T1 (de) 1994-09-02 1995-09-01 Nicht selbstinaktivierende retrovirale vektoren mit gezielter expression

Country Status (20)

Country Link
US (1) US7531353B1 (de)
EP (1) EP0779929B1 (de)
JP (1) JP4037446B2 (de)
CN (1) CN1117156C (de)
AT (1) ATE200517T1 (de)
AU (1) AU688590B2 (de)
BR (1) BR9508664A (de)
CA (1) CA2198210C (de)
DE (1) DE69520681T2 (de)
DK (1) DK0779929T5 (de)
EE (1) EE03492B1 (de)
ES (1) ES2156945T3 (de)
FI (1) FI970892A7 (de)
HU (1) HU221607B (de)
MX (1) MX9701544A (de)
NO (1) NO317731B1 (de)
NZ (1) NZ292897A (de)
PL (1) PL184375B1 (de)
RU (1) RU2199585C2 (de)
WO (1) WO1996007748A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4037446B2 (ja) 1994-09-02 2008-01-23 ゲーエスエフ − フォルシュンクスツェントルム・フューア・ウムベルト・ウント・ゲズントハイト・ゲーエムベーハー 非自己不活化性の発現標的化レトロウイルスベクタ
JP3908274B2 (ja) 1995-03-09 2007-04-25 ゲーエスエフ−フォルシュンクスツェントラム・フュア・ウムベルト・ウント・ゲズントハイト・ゲーエムベーハー 遺伝子治療用の抗菌ペプチドをコードする治療用遺伝子を有するベクター
DK0835137T3 (da) 1995-06-27 2006-03-06 Bavarian Nordic As Indkapslede celler, som danner viruspartikler
WO1997013867A1 (en) * 1995-10-13 1997-04-17 Bavarian Nordic Research Institute Retroviral vectors carrying senescent cell derived inhibitors 1 (sdi-1) or antisense sdi-1 nucleotide sequences
US7074398B1 (en) 1995-10-13 2006-07-11 Gsf-Forschungszentrum Fuer Umwelt Und Gesundheit Gmbh Retroviral vectors carrying senescent cell derived inhibitors 1 (SDI-1)or antisense SDI-1 nucleotide sequences
SI0892852T1 (sl) 1996-03-27 2006-04-30 Bavarian Nordic As Inkapsulirane celice, ki eksprimirajo citokrom P450 za aktiviranje predzdravila
US6540995B1 (en) 1996-03-27 2003-04-01 Bavarian Nordic Research Institute Gmbh Encapsulated cells producing cytochrome P450
WO1999032646A1 (en) * 1997-12-22 1999-07-01 Oxford Biomedica (Uk) Limited Equine infectious anaemia virus (eiav) based
EP0961830A1 (de) * 1997-01-29 1999-12-08 Neurosearch A/S Expressionvektoren und methoden zur in vivo expression von therapeutischen polypeptiden
ATE278029T1 (de) 1998-01-06 2004-10-15 Inst Virologie Teilrechtsfaehi Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression
FR2778670B1 (fr) * 1998-05-18 2002-12-13 Rhone Poulenc Rorer Sa Methodes et compositions pour la production de particules virales
DE19910650A1 (de) * 1999-03-10 2000-09-21 Gsf Forschungszentrum Umwelt Auf HERV-LTR-Sequenzen basierende retrovirale Expressionsvektoren
WO2000066758A1 (en) * 1999-04-29 2000-11-09 Aarhus University Expression of heterologous genes from an ires translational cassette in retroviral vectors
WO2002064805A2 (en) * 2001-02-09 2002-08-22 Institut für Virologie Teilrechtsfähiges Institut an der Veterinärmedizinischen Universität Wien Replication competent non-mammalian retroviral vectors
DE102009021592A1 (de) * 2009-05-15 2010-11-18 Medizinische Hochschule Hannover ASLV-Vektorsystem
CN120866241B (zh) * 2025-09-28 2026-01-30 深圳细胞谷生物医药有限公司 通过稳定细胞系生产工程化类病毒颗粒的方法及其工程化类病毒颗粒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE142268T1 (de) 1988-05-17 1996-09-15 Sloan Kettering Inst Cancer Retroviraler vektor
GB8919607D0 (en) * 1989-08-30 1989-10-11 Wellcome Found Novel entities for cancer therapy
WO1994029437A1 (en) * 1993-06-07 1994-12-22 University Of Medicine & Dentistry Of New Jersey Highly-efficient, self-inactivating, recombination-free, u3-free retroviral vectors
JP4037446B2 (ja) 1994-09-02 2008-01-23 ゲーエスエフ − フォルシュンクスツェントルム・フューア・ウムベルト・ウント・ゲズントハイト・ゲーエムベーハー 非自己不活化性の発現標的化レトロウイルスベクタ
JP3908274B2 (ja) * 1995-03-09 2007-04-25 ゲーエスエフ−フォルシュンクスツェントラム・フュア・ウムベルト・ウント・ゲズントハイト・ゲーエムベーハー 遺伝子治療用の抗菌ペプチドをコードする治療用遺伝子を有するベクター
DK0817859T3 (da) * 1995-03-09 2002-04-29 Austrian Nordic Biotherapeutic Rekombinante DNA vektorer til Genterapi
US6117681A (en) * 1995-03-29 2000-09-12 Bavarian Nordic Research Inst. A/S Pseudotyped retroviral particles
GB9510272D0 (en) 1995-05-22 1995-07-19 Isis Innovation Retroviral vectors
US7074398B1 (en) * 1995-10-13 2006-07-11 Gsf-Forschungszentrum Fuer Umwelt Und Gesundheit Gmbh Retroviral vectors carrying senescent cell derived inhibitors 1 (SDI-1)or antisense SDI-1 nucleotide sequences

Also Published As

Publication number Publication date
JP4037446B2 (ja) 2008-01-23
CN1159210A (zh) 1997-09-10
DE69520681T2 (de) 2001-11-29
AU3520195A (en) 1996-03-27
EP0779929B1 (de) 2001-04-11
FI970892L (fi) 1997-02-28
HU221607B (hu) 2002-11-28
EP0779929A1 (de) 1997-06-25
EE03492B1 (et) 2001-08-15
NO970902D0 (no) 1997-02-27
AU688590B2 (en) 1998-03-12
NZ292897A (en) 1998-08-26
CA2198210C (en) 2006-07-11
DE69520681D1 (de) 2001-05-17
WO1996007748A1 (en) 1996-03-14
NO970902L (no) 1997-04-24
RU2199585C2 (ru) 2003-02-27
PL184375B1 (pl) 2002-10-31
DK0779929T5 (da) 2001-08-13
FI970892A0 (fi) 1997-02-28
DK0779929T3 (da) 2001-05-07
PL319033A1 (en) 1997-07-21
EE9700040A (et) 1997-08-15
ES2156945T3 (es) 2001-08-01
CA2198210A1 (en) 1996-03-14
CN1117156C (zh) 2003-08-06
NO317731B1 (no) 2004-12-13
HK1001527A1 (en) 1998-06-26
BR9508664A (pt) 1998-01-06
FI970892A7 (fi) 1997-02-28
JPH10507628A (ja) 1998-07-28
HUT76974A (hu) 1998-01-28
MX9701544A (es) 1998-03-31
US7531353B1 (en) 2009-05-12

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