DE69920679D1 - Neue behandlungen für nervenkrankheiten - Google Patents

Neue behandlungen für nervenkrankheiten

Info

Publication number: DE69920679D1
Authority: DE; Germany
Prior art keywords: new treatments; nervous diseases; reboxetine; noradrenaline reuptake; new
Prior art date: 1998-04-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69920679T

Other languages

English (en)

Other versions

DE69920679T2 (de

Inventor

Adriana Dubini

Michael Mccall

Paul Taylor

Voigtlander F Von

Ho Wong

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Italia SRL

Pharmacia and Upjohn Co

Original Assignee

Pharmacia Italia SpA

Pharmacia and Upjohn Co

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-04-13

Filing date

1999-04-02

Publication date

2004-11-04

1999-04-02 Application filed by Pharmacia Italia SpA, Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia Italia SpA

2004-11-04 Publication of DE69920679D1 publication Critical patent/DE69920679D1/de

2006-03-02 Application granted granted Critical

2006-03-02 Publication of DE69920679T2 publication Critical patent/DE69920679T2/de

2019-04-03 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
238000011282 treatment Methods 0.000 title 1
208000021384 Obsessive-Compulsive disease Diseases 0.000 abstract 2
CBQGYUDMJHNJBX-RTBURBONSA-N reboxetine Chemical compound CCOC1=CC=CC=C1O[C@H](C=1C=CC=CC=1)[C@@H]1OCCNC1 CBQGYUDMJHNJBX-RTBURBONSA-N 0.000 abstract 2
229960003770 reboxetine Drugs 0.000 abstract 2
230000001430 anti-depressive effect Effects 0.000 abstract 1
239000000935 antidepressant agent Substances 0.000 abstract 1
229940005513 antidepressants Drugs 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
230000010534 mechanism of action Effects 0.000 abstract 1
239000002858 neurotransmitter agent Substances 0.000 abstract 1
239000002767 noradrenalin uptake inhibitor Substances 0.000 abstract 1
229940126569 noradrenaline reuptake inhibitor Drugs 0.000 abstract 1
230000000966 norepinephrine reuptake Effects 0.000 abstract 1
208000019906 panic disease Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Mobile Radio Communication Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DE69920679T 1998-04-13 1999-04-02 Neue behandlungen für nervenkrankheiten Expired - Fee Related DE69920679T2 (de)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
US8163298P	1998-04-13	1998-04-13
US81632P		1998-04-13
ITMI980870		1998-04-23
IT98MI000870 IT1305322B1 (it)	1998-04-23	1998-04-23	Uso di reboxetina per il trattamento di disturbi nervosi
US8503398P	1998-05-11	1998-05-11
US85033P		1998-05-11
PCT/US1999/004288 WO1999052518A2 (en)	1998-04-13	1999-04-02	New treatments for nervous disorders

Publications (2)

Publication Number	Publication Date
DE69920679D1 true DE69920679D1 (de)	2004-11-04
DE69920679T2 DE69920679T2 (de)	2006-03-02

Family

ID=11379879

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69920679T Expired - Fee Related DE69920679T2 (de)	1998-04-13	1999-04-02	Neue behandlungen für nervenkrankheiten

Country Status (25)

Country	Link
US (1)	US6391876B1 (de)
EP (1)	EP1071418B1 (de)
JP (1)	JP2002511408A (de)
KR (1)	KR100555279B1 (de)
CN (1)	CN1197569C (de)
AT (1)	ATE277617T1 (de)
AU (1)	AU755612B2 (de)
BR (1)	BR9909476A (de)
CA (1)	CA2320722A1 (de)
DE (1)	DE69920679T2 (de)
DK (1)	DK1071418T3 (de)
EA (1)	EA003546B1 (de)
ES (1)	ES2228035T3 (de)
HU (1)	HUP0101748A3 (de)
IL (1)	IL138887A0 (de)
IT (1)	IT1305322B1 (de)
NO (1)	NO20005131L (de)
NZ (1)	NZ507693A (de)
PL (1)	PL194039B1 (de)
PT (1)	PT1071418E (de)
SI (1)	SI1071418T1 (de)
SK (1)	SK14482000A3 (de)
TR (1)	TR200002970T2 (de)
WO (1)	WO1999052518A2 (de)
ZA (1)	ZA200004480B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6500827B2 (en) *	1998-05-08	2002-12-31	Pharmacia & Upjohn Company	Drug combinations
US6465458B1 (en)	1999-07-01	2002-10-15	Pharmacia & Upjohn Company	Method of treating or preventing chronic pain with a highly selective norepinephrine reuptake inhibitor
SI1196172T1 (sl) *	1999-07-01	2006-06-30	Pharmacia & Upjohn Co Llc	(S,S)-reboksetin za zdravljenje kronicne bolecine
BR0115301A (pt) *	2000-11-15	2004-12-14	Lilly Co Eli	Uso de um inibidor seletivo da recaptação de norepinefrina
CN1662511B (zh) *	2002-06-17	2010-06-09	辉瑞意大利公司	瑞波西汀的药物盐
US20100069389A1 (en) *	2008-09-06	2010-03-18	Bionevia Pharmaceuticals, Inc.	Novel forms of reboxetine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL56369A (en)	1978-01-20	1984-05-31	Erba Farmitalia	Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them
GB8419683D0 (en)	1984-08-02	1984-09-05	Erba Farmitalia	3-substituted derivatives of 1-amino-2-hydroxy-propane
GB2167407B (en)	1984-11-22	1988-05-11	Erba Farmitalia	Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereof
AU9692898A (en)	1997-10-17	1999-05-10	Eli Lilly And Company	Potentiation of pharmaceuticals

1998
- 1998-04-23 IT IT98MI000870 patent/IT1305322B1/it active
1999
- 1999-04-02 KR KR1020007011336A patent/KR100555279B1/ko not_active Expired - Fee Related
- 1999-04-02 US US09/673,768 patent/US6391876B1/en not_active Expired - Fee Related
- 1999-04-02 BR BR9909476-2A patent/BR9909476A/pt not_active Application Discontinuation
- 1999-04-02 AT AT99918423T patent/ATE277617T1/de not_active IP Right Cessation
- 1999-04-02 EA EA200001058A patent/EA003546B1/ru not_active IP Right Cessation
- 1999-04-02 CA CA002320722A patent/CA2320722A1/en not_active Abandoned
- 1999-04-02 NZ NZ507693A patent/NZ507693A/en unknown
- 1999-04-02 PT PT99918423T patent/PT1071418E/pt unknown
- 1999-04-02 JP JP2000543128A patent/JP2002511408A/ja active Pending
- 1999-04-02 DE DE69920679T patent/DE69920679T2/de not_active Expired - Fee Related
- 1999-04-02 CN CNB99804010XA patent/CN1197569C/zh not_active Expired - Fee Related
- 1999-04-02 WO PCT/US1999/004288 patent/WO1999052518A2/en not_active Ceased
- 1999-04-02 IL IL13888799A patent/IL138887A0/xx not_active IP Right Cessation
- 1999-04-02 TR TR2000/02970T patent/TR200002970T2/xx unknown
- 1999-04-02 EP EP99918423A patent/EP1071418B1/de not_active Expired - Lifetime
- 1999-04-02 HU HU0101748A patent/HUP0101748A3/hu active IP Right Revival
- 1999-04-02 SK SK1448-2000A patent/SK14482000A3/sk unknown
- 1999-04-02 SI SI9930684T patent/SI1071418T1/xx unknown
- 1999-04-02 ES ES99918423T patent/ES2228035T3/es not_active Expired - Lifetime
- 1999-04-02 PL PL99346294A patent/PL194039B1/pl unknown
- 1999-04-02 AU AU36351/99A patent/AU755612B2/en not_active Ceased
- 1999-04-02 DK DK99918423T patent/DK1071418T3/da active
2000
- 2000-08-29 ZA ZA200004480A patent/ZA200004480B/en unknown
- 2000-10-12 NO NO20005131A patent/NO20005131L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO20005131D0 (no)	2000-10-12
CA2320722A1 (en)	1999-10-21
HUP0101748A3 (en)	2001-12-28
ITMI980870A1 (it)	1999-10-23
EP1071418B1 (de)	2004-09-29
CN1197569C (zh)	2005-04-20
DK1071418T3 (da)	2005-01-03
EA200001058A1 (ru)	2001-04-23
NO20005131L (no)	2000-10-12
SK14482000A3 (sk)	2001-08-06
DE69920679T2 (de)	2006-03-02
BR9909476A (pt)	2000-12-19
CN1293569A (zh)	2001-05-02
WO1999052518A2 (en)	1999-10-21
PL194039B1 (pl)	2007-04-30
TR200002970T2 (tr)	2001-01-22
AU755612B2 (en)	2002-12-19
KR100555279B1 (ko)	2006-03-03
US6391876B1 (en)	2002-05-21
HUP0101748A2 (hu)	2001-11-28
IT1305322B1 (it)	2001-05-04
EA003546B1 (ru)	2003-06-26
ATE277617T1 (de)	2004-10-15
IL138887A0 (en)	2001-11-25
JP2002511408A (ja)	2002-04-16
EP1071418A2 (de)	2001-01-31
SI1071418T1 (en)	2005-04-30
PL346294A1 (en)	2002-01-28
ES2228035T3 (es)	2005-04-01
AU3635199A (en)	1999-11-01
NZ507693A (en)	2003-08-29
WO1999052518A3 (en)	1999-12-02
PT1071418E (pt)	2004-12-31
KR20010042641A (ko)	2001-05-25
ZA200004480B (en)	2002-04-24

Legal Events

Date	Code	Title	Description
2005-10-27	8364	No opposition during term of opposition
2009-02-19	8339	Ceased/non-payment of the annual fee

Publication	Publication Date	Title
ATE277617T1 (de)	2004-10-15	Neue behandlungen für nervenkrankheiten
MY134110A (en)	2007-11-30	Combinations of reboxetine and neuroleptic agents
FI972922A0 (fi)	1997-07-09	Tarkkaamattomuuden ja yliaktiivisuuden hoito
ATE329588T1 (de)	2006-07-15	Verwendung von sibutramin zur behandlung von von organischen störungen verursachten zns- erkrankungen
NO2012015I2 (no)	2013-08-26	Dapoxetine
PT946166E (pt)	2004-06-30	Utilizacao de inibidores das metaloproteinases da matriz para tratar disturbios neurologicos e promover a cicatrizacao de feridas
WO2002077198A3 (en)	2002-11-28	Methods of modulating angiogenesis
MY143278A (en)	2011-04-15	Treatment of neurotic disorders.
ES2118569T3 (es)	1998-09-16	Procedimiento para la regeneracion de un catalizador.
MY136367A (en)	2008-09-30	Treatment of cognitive failure
WO2002040006A3 (en)	2003-12-24	Treatment of anxiety disorders
ATE283694T1 (de)	2004-12-15	Neue arzneimittelkombinationen aus reboxetin und pindolol
CO4950552A1 (es)	2000-09-01	Nueva composicion lectivos de la reabsorcion de seotonina y un bloqueador b
PT1054671E (pt)	2003-03-31	Nova utilizacao da ropivacaina para o controlo da dor
BR0115880A (pt)	2004-01-06	Emprego de compostos ciclohexanona de 6-dimetilaminometila-1-fenil para o tratamento da incontinência urinária
BR0115881A (pt)	2004-01-20	Emprego de compostos ciclohexanona substituìdos de 6-dimetilaminometil-1-fenil para a terapia da incontinência urinária
ECSP034647A (es)	2003-07-25	Uso de factor vii actividad de coagulacion para tratar sangrados graves inducidos por terapia
ATE406880T1 (de)	2008-09-15	Behandlung von motorischen veränderungen mit 5- hydrxoytryptamin 1a rezeptor aktivität verstärkenden wirkstoffen
ES2122953T1 (es)	1999-01-01	Utilizacion de inhibidores pkc para la fabricacion de un medicamento para el tratamiento de las disfunciones sexuales.
PT1282414E (pt)	2005-04-29	Compostos derivados de felbamato para o tratamento da dor neuropatica
CY1110278T1 (el)	2015-01-14	Μεθοδος διαλογης παραγοντων ικανων να θεραπευουν την παχυσαρκια
DK1558610T3 (da)	2008-06-23	Substituerede aminoquinuclidinforbindelser og deres anvendelse som delta-opioidreceptorligander
FI972378A0 (fi)	1997-06-05	Menetelmä orgaanisia ja epäorgaanisia yhdisteitä sisältävien jätevesien katalyyttiseksi käsittelemiseksi
ZA991638B (en)	1999-09-01	Method of treating obsessive compulsive disorders, somatoform disorders, dissociative disorders, eating disorders, impulse control disorders and autism.
ECSP992873A (es)	1999-06-01	Metodo para tratar desordenes compulsivos, obsesivos, desordenes somatoformes, desordenes disociativos, desordenes al comer, desordenes de control de impulso, y autismo (caso cn0823)