DK0402950T3 - Behandling af postmenopausale ulemper - Google Patents

Behandling af postmenopausale ulemper

Info

Publication number: DK0402950T3
Authority: DK; Denmark
Prior art keywords: daily; separate; dosage units; sequential; compound
Prior art date: 1989-06-15

Application number

DK90111365.4T

Other languages

English (en)

Inventor

Erkki Hirvonen

Ariel Gordin

Original Assignee

Orion Yhtym Oy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-15

Filing date

1990-06-15

Publication date

1993-10-25

1990-06-15 Application filed by Orion Yhtym Oy filed Critical Orion Yhtym Oy

1993-10-25 Application granted granted Critical

1993-10-25 Publication of DK0402950T3 publication Critical patent/DK0402950T3/da

Links

150000001875 compounds Chemical class 0.000 abstract 3
230000037406 food intake Effects 0.000 abstract 3
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
208000035475 disorder Diseases 0.000 abstract 2
230000001076 estrogenic effect Effects 0.000 abstract 2
RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Natural products C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 1
201000006828 endometrial hyperplasia Diseases 0.000 abstract 1
239000000262 estrogen Substances 0.000 abstract 1
229940011871 estrogen Drugs 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
230000001072 progestational effect Effects 0.000 abstract 1
229960003387 progesterone Drugs 0.000 abstract 1
239000000186 progesterone Substances 0.000 abstract 1
-1 progesterone compound Chemical class 0.000 abstract 1
239000000583 progesterone congener Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Crystals, And After-Treatments Of Crystals (AREA)
Medicines Containing Plant Substances (AREA)

DK90111365.4T 1989-06-15 1990-06-15 Behandling af postmenopausale ulemper DK0402950T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/366,424 US5043331A (en)	1989-06-15	1989-06-15	Treatment of postmenopausal disorders

Publications (1)

Publication Number	Publication Date
DK0402950T3 true DK0402950T3 (da)	1993-10-25

Family

ID=23442937

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90111365.4T DK0402950T3 (da)	1989-06-15	1990-06-15	Behandling af postmenopausale ulemper

Country Status (10)

Country	Link
US (1)	US5043331A (da)
EP (1)	EP0402950B1 (da)
JP (1)	JPH0331213A (da)
AT (1)	ATE93728T1 (da)
AU (1)	AU635270B2 (da)
CA (1)	CA2018818C (da)
DE (2)	DE69003015D1 (da)
DK (1)	DK0402950T3 (da)
IE (1)	IE65864B1 (da)
NZ (1)	NZ234051A (da)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU222501B1 (hu) *	1991-06-28	2003-07-28	Endorecherche Inc.	MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
ZA924811B (en) *	1991-06-28	1993-12-29	Endorecherche Inc	Controlled release systems and low dose androgens
JP2722025B2 (ja) *	1991-07-19	1998-03-04	日本鋼管工事株式会社	光ファイバ融着部測定システム
DE4405590C1 (de) *	1994-02-22	1995-07-20	Hesch Rolf Dieter Prof Dr Med	Mittel zur postmenopausalen Hormonbehandlung
DE19815060A1 (de) *	1998-04-03	1999-10-14	Jenapharm Gmbh	Pharmazeutische Präparate zur Therapie von Nebenwirkungen während und/oder nach einer GnRHa-Therapie
US6165504A (en) *	1998-09-23	2000-12-26	Barr Laboratories, Inc.	Methods for treating hot flashes and improving the quality of life of castrated prostatic cancer patients
US6855703B1 (en)	2000-03-10	2005-02-15	Endeavor Pharmaceuticals	Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
US7459445B2 (en) *	2000-03-10	2008-12-02	Duramed Pharmaceuticals, Inc.	Estrogenic compounds and topical pharmaceutical formulations of the same
US7989436B2 (en) *	2003-07-23	2011-08-02	Duramed Pharmaceuticals, Inc.	Estrogenic compounds and pharmaceutical formulations comprising the same
US6660726B2 (en)	2000-03-10	2003-12-09	Endeavor Pharmaceuticals	Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
US20020151530A1 (en)	2000-12-22	2002-10-17	Leonard Thomas W.	Method of treating hormonal deficiencies in women undergoing estrogen replacement therapy
CA2446849A1 (en) *	2001-05-16	2002-11-21	Endeavor Pharmaceuticals	Treatment of conditions relating to hormone deficiencies by administration of progestins
DE60217324T2 (de)	2001-05-18	2007-04-26	Pantarhei Bioscience B.V.	Pharmazeutische zusammensetzung für die hormonersatztherapie
US7732430B2 (en)	2001-05-23	2010-06-08	Pantarhei Bioscience B.V.	Drug delivery system comprising a tetrahydroxilated estrogen for use in hormonal contraception
EP1390041B1 (en)	2001-05-23	2009-11-25	Pantarhei Bioscience B.V.	Drug delivery system comprising a tetrahydroxylated estrogen for use in hormonal contraception
ATE347365T1 (de) *	2001-11-15	2006-12-15	Pantarhei Bioscience Bv	Verwendung von öestrogen in kombination mit progestogen für die hormonsubstitutions-therapie
MXPA04005445A (es) *	2001-12-05	2005-03-23	Barr Lab Inc	Anticonceptivos orales para prevenir el embarazo y disminuir la sintomatologia premenstrual.
EP1340503A1 (en) *	2002-03-01	2003-09-03	CHIESI FARMACEUTICI S.p.A.	Solution aerosol formulation containing esters of 3, 17-dihydroxy oestratriene derivates for pulmonary delivery
BR0309032A (pt) *	2002-04-03	2005-02-01	Barr Lab Inc	Método para tratar sintomas vasomotores, a menopausa, deficiências hormonais em um paciente, e para tratar um paciente que sofre de sintomas vasomotores
AU2003274946A1 (en)	2002-06-11	2003-12-22	Pantarhei Bioscience B.V.	Method of treating or preventing immune mediated disorders and pharmaceutical formulation for use therein
CA2489270C (en)	2002-06-11	2012-08-07	Pantarhei Bioscience B.V.	A method of treating human skin and a skin care composition for use in such a method
US9034854B2 (en)	2002-07-12	2015-05-19	Pantarhei Bioscience B.V.	Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy
US8987240B2 (en)	2002-10-23	2015-03-24	Pantarhei Bioscience B.V.	Pharmaceutical compositions comprising estetrol derivatives for use in cancer therapy
US6992075B2 (en) *	2003-04-04	2006-01-31	Barr Laboratories, Inc.	C(14) estrogenic compounds
WO2004091535A2 (en) *	2003-04-11	2004-10-28	Barr Laboratories, Inc.	Methods of administering estrogens and progestins
JP2006525358A (ja) *	2003-05-02	2006-11-09	ドゥラメドファーマシューティカルズ，インコーポレイテッド	長期周期避妊養生法を利用するホルモン治療の方法
NZ585546A (en) *	2003-07-16	2011-10-28	Teva Womens Health Inc	Methods of hormonal treatment utilizing contraceptive regimens with continuous estrogen administration
JP2007507534A (ja) *	2003-10-01	2007-03-29	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	持続的三相避妊方法
US20070111975A1 (en)	2004-10-07	2007-05-17	Duramed Pharmaceuticals, Inc.	Methods of Hormonal Treatment Utilizing Ascending-Dose Extended Cycle Regimens
CN101583363B (zh)	2007-01-08	2013-08-21	潘塔希生物科学股份有限公司	治疗或预防雌性哺乳动物不育症的方法和此类方法中使用的药物试剂盒
RS62297B1 (sr)	2011-11-23	2021-09-30	Therapeuticsmd Inc	Prirodne kombinovane hormonske supstitucione formulacije i terapije
US9301920B2 (en)	2012-06-18	2016-04-05	Therapeuticsmd, Inc.	Natural combination hormone replacement formulations and therapies
US10806697B2 (en)	2012-12-21	2020-10-20	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en)	2012-06-18	2020-10-20	Therapeuticsmd, Inc.	Natural combination hormone replacement formulations and therapies
US10568891B2 (en)	2012-12-21	2020-02-25	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en)	2012-12-21	2020-01-21	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en)	2012-12-21	2022-03-08	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en)	2012-12-21	2015-11-10	Therapeuticsmd, Inc.	Soluble estradiol capsule for vaginal insertion
RU2016143081A (ru)	2014-05-22	2018-06-26	Терапьютиксмд, Инк.	Натуральные комбинированные гормонозаместительные составы и терапии
KR20200013771A (ko) *	2017-06-08	2020-02-07	쎄러퓨틱스엠디, 인코퍼레이티드	질 삽입 에스트라디올 약학적 조성물 및 방법
US11633405B2 (en)	2020-02-07	2023-04-25	Therapeuticsmd, Inc.	Steroid hormone pharmaceutical formulations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4425339A (en) *	1981-04-09	1984-01-10	Syntex (U.S.A.) Inc.	Treatment of menopausal symptoms
US4826831A (en) *	1983-08-05	1989-05-02	Pre Jay Holdings Limited	Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens
IE61236B1 (en) *	1986-07-15	1994-10-19	American Home Prod	Combination dosage form for pre-menopausal women

1989
- 1989-06-15 US US07/366,424 patent/US5043331A/en not_active Expired - Lifetime
1990
- 1990-05-23 AU AU55876/90A patent/AU635270B2/en not_active Ceased
- 1990-06-12 CA CA002018818A patent/CA2018818C/en not_active Expired - Fee Related
- 1990-06-13 NZ NZ234051A patent/NZ234051A/xx unknown
- 1990-06-14 JP JP2156610A patent/JPH0331213A/ja active Pending
- 1990-06-15 AT AT90111365T patent/ATE93728T1/de not_active IP Right Cessation
- 1990-06-15 DK DK90111365.4T patent/DK0402950T3/da active
- 1990-06-15 DE DE90111365A patent/DE69003015D1/de not_active Expired - Fee Related
- 1990-06-15 IE IE216490A patent/IE65864B1/en not_active IP Right Cessation
- 1990-06-15 DE DE69003015T patent/DE69003015T4/de not_active Expired - Lifetime
- 1990-06-15 EP EP90111365A patent/EP0402950B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH0331213A (ja)	1991-02-12
CA2018818A1 (en)	1990-12-15
EP0402950A2 (en)	1990-12-19
EP0402950B1 (en)	1993-09-01
ATE93728T1 (de)	1993-09-15
US5043331A (en)	1991-08-27
IE65864B1 (en)	1995-11-29
IE902164L (en)	1990-12-15
NZ234051A (en)	1991-09-25
AU5587690A (en)	1990-12-20
EP0402950A3 (en)	1991-02-06
AU635270B2 (en)	1993-03-18
DE69003015T4 (de)	1994-05-26
CA2018818C (en)	2001-01-16
DE69003015T2 (de)	1993-12-16
DE69003015D1 (de)	1993-10-07
IE902164A1 (en)	1991-01-02

Publication	Publication Date	Title
DE69003015D1 (de)	1993-10-07	Behandlung von Störungen in der Postmenopause.
NO914970D0 (no)	1991-12-16	Prostagen-bare kontraseptiv
MD1920F2 (ro)	2002-05-31	Compoziţie şi metodă de profilaxie sau frânare a debutului bolii Alzheimer
NZ219776A (en)	1990-03-27	11-substituted steroid 17, 2'-furan derivatives and pharmaceutical compositions
TR199802705T2 (xx)	1999-03-22	Progestojen-anti-progestojen k�r�
FI970526A7 (fi)	1997-02-07	Estra-1,3,5(10)-trieenijohdannaiset, niiden valmistusmenetelmät sekä n äitä yhdisteitä sisältävät farmaseuttiset koostumukset
GB2213484B (en)	1991-10-09	New derivatives of 17beta-oh 19-nor steroids substituted in the 17 alpha position, their preparation, their use as medicaments and pharmaceutical compositions
ATE155039T1 (de)	1997-07-15	Mit zucker überzogene pharmazeutische dosierungseinheit
BR0114665A (pt)	2004-01-13	Uso de antiprogestinas para a profilaxia e tratamento de doenças dependentes de hormÈnio
FI971742A7 (fi)	1997-04-23	Kompetitiivisia progesteroniantagonisteja tarpeen sanelemaan raskauden ehkäisyyn naisilla
EP0438147A3 (en)	1991-10-16	Pharmaceutical compositions and dosage forms for the oral administration of calcitonin
MX9702253A (es)	1997-06-28	Nuevos estrenos para inducir efectos hipotalamicos
NZ504351A (en)	2002-10-25	Contraceptive kit comprising progestogen and anti-progestogen and use in treating bleeding induced by a progestogen-only contraceptive regimen
ITMI913510A1 (it)	1993-07-01	Composizioni farmaceutiche contenenti progesterone ad elevata biodisponibilita'
CA2248841A1 (en)	1997-09-18	Sequential oestrogen/progesterone antagonist combination for hormone replacement therapy
ES8703872A1 (es)	1987-03-01	Procedimiento para preparar derivados de isoquinolina.
FR2713088B1 (fr)	1996-03-22	Utilisation de la vitamine B1 et ses dérivés pour la préparation d'un médicament destiné au traitement des affections dont les symptômes sont attribués aux désordres d'origine vasculaire.
FR2602680B1 (fr)	1993-04-16	Compositions pharmaceutiques pour l'administration par voie nasale
RU96124465A (ru)	1999-02-20	Способ лечения стойких дезадаптационных психовегетативных расстройств
IL137496A0 (en)	2001-07-24	Dosage form and pharmaceutical kit for increasing the oral availablity of pharmaceutical agents