DK0404440T3 - Substituerede sulfonamider og beslægtede forbindelser til behandling af astma, arthritis og beslægtede sygdomme - Google Patents
Substituerede sulfonamider og beslægtede forbindelser til behandling af astma, arthritis og beslægtede sygdommeInfo
- Publication number
- DK0404440T3 DK0404440T3 DK90306500.1T DK90306500T DK0404440T3 DK 0404440 T3 DK0404440 T3 DK 0404440T3 DK 90306500 T DK90306500 T DK 90306500T DK 0404440 T3 DK0404440 T3 DK 0404440T3
- Authority
- DK
- Denmark
- Prior art keywords
- asthma
- arthritis
- treatment
- substituted sulfonamides
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 206010003246 arthritis Diseases 0.000 title 1
- 208000006673 asthma Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 229940124530 sulfonamide Drugs 0.000 title 1
- 150000003456 sulfonamides Chemical class 0.000 title 1
- 102000001381 Arachidonate 5-Lipoxygenase Human genes 0.000 abstract 1
- 108010093579 Arachidonate 5-lipoxygenase Proteins 0.000 abstract 1
- GWNVDXQDILPJIG-SHSCPDMUSA-N Leukotriene C4 Natural products CCCCCC=C/CC=C/C=C/C=C/C(SCC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O)C(O)CCCC(=O)O GWNVDXQDILPJIG-SHSCPDMUSA-N 0.000 abstract 1
- OTZRAYGBFWZKMX-SHSCPDMUSA-N Leukotriene E4 Natural products CCCCCC=C/CC=C/C=C/C=C/C(SCC(N)C(=O)O)C(O)CCCC(=O)O OTZRAYGBFWZKMX-SHSCPDMUSA-N 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- GWNVDXQDILPJIG-NXOLIXFESA-N leukotriene C4 Chemical compound CCCCC\C=C/C\C=C/C=C/C=C/[C@H]([C@@H](O)CCCC(O)=O)SC[C@@H](C(=O)NCC(O)=O)NC(=O)CC[C@H](N)C(O)=O GWNVDXQDILPJIG-NXOLIXFESA-N 0.000 abstract 1
- YEESKJGWJFYOOK-IJHYULJSSA-N leukotriene D4 Chemical compound CCCCC\C=C/C\C=C/C=C/C=C/[C@H]([C@@H](O)CCCC(O)=O)SC[C@H](N)C(=O)NCC(O)=O YEESKJGWJFYOOK-IJHYULJSSA-N 0.000 abstract 1
- OTZRAYGBFWZKMX-JUDRUQEKSA-N leukotriene E4 Chemical compound CCCCCC=CCC=C\C=C\C=C\[C@@H](SC[C@H](N)C(O)=O)[C@@H](O)CCCC(O)=O OTZRAYGBFWZKMX-JUDRUQEKSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1989/002748 WO1990015801A1 (en) | 1989-06-22 | 1989-06-22 | Substituted sulfonamides and related compounds in the treatment of asthma, arthritis and related diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0404440T3 true DK0404440T3 (da) | 1997-12-22 |
Family
ID=22215089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90306500.1T DK0404440T3 (da) | 1989-06-22 | 1990-06-14 | Substituerede sulfonamider og beslægtede forbindelser til behandling af astma, arthritis og beslægtede sygdomme |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0404440B1 (da) |
| JP (1) | JPH0753722B2 (da) |
| AT (1) | ATE159941T1 (da) |
| CA (1) | CA2019349A1 (da) |
| DE (1) | DE69031669T2 (da) |
| DK (1) | DK0404440T3 (da) |
| ES (1) | ES2109229T3 (da) |
| FI (1) | FI96951C (da) |
| GR (1) | GR3025697T3 (da) |
| IE (1) | IE902245A1 (da) |
| WO (1) | WO1990015801A1 (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU222344B1 (hu) * | 1990-10-12 | 2003-06-28 | Merck Frosst Canada & Co. | Eljárás telítetlen hidroxi-alkil-kinolinsavak, és ezeket tartalmazó gyógyszerkészítmények előállítására |
| AU2773392A (en) * | 1992-01-23 | 1993-09-01 | Pfizer Inc. | Benzopyran and related LTB4 antagonists |
| MX9300312A (es) * | 1992-01-23 | 1993-07-31 | Pfizer | Antagonistas benzopiranicos y relacionado de ltb. |
| US5641789A (en) * | 1992-10-21 | 1997-06-24 | Pfizer Inc. | Sulfonamide derivatives of benzenefused hydroxy substituted cycloalkyl and heterocyclic ring compounds |
| US5591752A (en) * | 1993-02-16 | 1997-01-07 | Ube Industries, Ltd. | Quinoline derivative |
| ES2084547B1 (es) * | 1993-07-12 | 1997-01-16 | Pfizer | Antagonistas benzopiranicos y relacionados de leucotrieno b4. |
| US5539128A (en) * | 1994-11-30 | 1996-07-23 | Pfizer Inc. | Processes and intermediates for preparing cis(+)3-[4,6-dihydroxy chroman-3-ylmethyl]-4-methoxyaniline |
| IL127559A0 (en) | 1996-06-20 | 1999-10-28 | Univ Texas | Compounds and methods for providing pharmacologically active preparations and uses thereof |
| RU2251419C2 (ru) * | 2000-06-21 | 2005-05-10 | Ф. Хоффманн-Ля Рош Аг | Производные бензотиазола |
| US7087761B2 (en) | 2003-01-07 | 2006-08-08 | Hoffmann-La Roche Inc. | Cyclization process for substituted benzothiazole derivatives |
| AU2005247567B2 (en) | 2004-05-24 | 2010-09-02 | F. Hoffmann-La Roche Ag | 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide |
| EP1812392B1 (en) | 2004-11-05 | 2008-07-09 | F.Hoffmann-La Roche Ag | Process for preparation of isonicotinic acid derivatives |
| PT1863818E (pt) | 2005-03-23 | 2010-04-09 | Hoffmann La Roche | Derivados de acetilenil-pirazolo-pirimidina como antagonistas de mglur2 |
| ATE463495T1 (de) | 2005-09-27 | 2010-04-15 | Hoffmann La Roche | Oxadiazolylpyrazolopyrimidine als mglur2- antagonisten |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4675405A (en) * | 1984-09-21 | 1987-06-23 | American Home Products Corporation | Quinoline compounds as antiallergic and antithrombotic agents |
| US4845105A (en) * | 1984-10-30 | 1989-07-04 | Roussel Uclaf | 4-OH-quinoline carboxylic acid amides having analgesic and anti-inflammatory activity |
| US4661596A (en) * | 1985-02-21 | 1987-04-28 | American Home Products Corporation | Quinolinyl (or pyridinyl) methoxy substituted naphthalene compounds as antiallergic agents |
| US4738972A (en) * | 1985-05-21 | 1988-04-19 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
| GB8613592D0 (en) * | 1986-06-04 | 1986-07-09 | Roussel Lab Ltd | Chemical compounds |
| MX13485A (es) * | 1987-10-19 | 1993-05-01 | Pfizer | Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos |
-
1989
- 1989-06-22 WO PCT/US1989/002748 patent/WO1990015801A1/en not_active Ceased
-
1990
- 1990-06-14 AT AT90306500T patent/ATE159941T1/de not_active IP Right Cessation
- 1990-06-14 ES ES90306500T patent/ES2109229T3/es not_active Expired - Lifetime
- 1990-06-14 EP EP90306500A patent/EP0404440B1/en not_active Expired - Lifetime
- 1990-06-14 DK DK90306500.1T patent/DK0404440T3/da active
- 1990-06-14 DE DE69031669T patent/DE69031669T2/de not_active Expired - Fee Related
- 1990-06-20 CA CA002019349A patent/CA2019349A1/en not_active Abandoned
- 1990-06-21 IE IE224590A patent/IE902245A1/en unknown
- 1990-06-22 JP JP2165484A patent/JPH0753722B2/ja not_active Expired - Lifetime
-
1991
- 1991-12-20 FI FI916065A patent/FI96951C/fi active
-
1997
- 1997-12-17 GR GR970403348T patent/GR3025697T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3025697T3 (en) | 1998-03-31 |
| ATE159941T1 (de) | 1997-11-15 |
| FI916065A0 (fi) | 1991-12-20 |
| EP0404440A2 (en) | 1990-12-27 |
| WO1990015801A1 (en) | 1990-12-27 |
| EP0404440A3 (en) | 1992-01-08 |
| ES2109229T3 (es) | 1998-01-16 |
| JPH0338569A (ja) | 1991-02-19 |
| FI96951B (fi) | 1996-06-14 |
| DE69031669D1 (de) | 1997-12-11 |
| DE69031669T2 (de) | 1998-03-05 |
| JPH0753722B2 (ja) | 1995-06-07 |
| CA2019349A1 (en) | 1990-12-22 |
| IE902245A1 (en) | 1991-01-16 |
| IE902245L (en) | 1990-12-22 |
| FI96951C (fi) | 1996-09-25 |
| EP0404440B1 (en) | 1997-11-05 |
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