DK0409521T3 - Forbedret enzymatisk oxidation af Ceph C til glutaryl-7-aminocephalosporansyre - Google Patents

Forbedret enzymatisk oxidation af Ceph C til glutaryl-7-aminocephalosporansyre

Info

Publication number: DK0409521T3
Authority: DK; Denmark
Prior art keywords: glutaryl; ceph; enzymatic oxidation; enhanced enzymatic; aminocephalosporanoic acid
Prior art date: 1989-07-19

Application number

DK90307738.6T

Other languages

English (en)

Inventor

Jeffrey Thomas Vicenzi

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-07-19

Filing date

1990-07-16

Publication date

1996-02-05

1990-07-16 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1996-02-05 Application granted granted Critical

1996-02-05 Publication of DK0409521T3 publication Critical patent/DK0409521T3/da

Links

230000002255 enzymatic effect Effects 0.000 title abstract 2
230000003647 oxidation Effects 0.000 title abstract 2
238000007254 oxidation reaction Methods 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
IXUSDMGLUJZNFO-BXUZGUMPSA-N (7R)-7-(4-carboxybutanamido)cephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCCC(O)=O)[C@@H]12 IXUSDMGLUJZNFO-BXUZGUMPSA-N 0.000 abstract 1
108090000371 Esterases Proteins 0.000 abstract 1
230000009849 deactivation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
- C12N9/0024—D-Amino acid oxidase (1.4.3.3)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/99—Enzyme inactivation by chemical treatment

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cephalosporin Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)

DK90307738.6T 1989-07-19 1990-07-16 Forbedret enzymatisk oxidation af Ceph C til glutaryl-7-aminocephalosporansyre DK0409521T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US38250589A	1989-07-19	1989-07-19

Publications (1)

Publication Number	Publication Date
DK0409521T3 true DK0409521T3 (da)	1996-02-05

Family

ID=23509253

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90307738.6T DK0409521T3 (da)	1989-07-19	1990-07-16	Forbedret enzymatisk oxidation af Ceph C til glutaryl-7-aminocephalosporansyre

Country Status (13)

Country	Link
US (2)	US5424203A (da)
EP (2)	EP0409521B1 (da)
JP (1)	JP2883173B2 (da)
KR (1)	KR0163175B1 (da)
AT (1)	ATE129012T1 (da)
CA (2)	CA2268710C (da)
DE (1)	DE69022909T2 (da)
DK (1)	DK0409521T3 (da)
ES (1)	ES2079442T3 (da)
GR (1)	GR3017731T3 (da)
HU (1)	HU212587B (da)
IE (1)	IE71523B1 (da)
IL (1)	IL95090A (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE129012T1 (de) *	1989-07-19	1995-10-15	Lilly Co Eli	Enzymatische oxidation von ceph c zu glutaryl-7- aminocephalosporansäure.
DE4028119C1 (da) *	1990-09-05	1991-12-05	Hoechst Ag, 6230 Frankfurt, De
CA2100987C (en) *	1992-07-27	1999-06-15	Kaoru Furuya	A transformant capable of producing d-amino acid oxidase
EP0600247A3 (de) *	1992-11-05	1995-05-10	Hoechst Ag	Verfahren zur selektiven Desaktivierung von unerwünschten Proteinen in einem Proteingemisch mittels Mikrowelleneinstrahlung.
GB2275925B (en) *	1993-03-08	1996-08-14	Asahi Chemical Ind	A process for converting cephalosporin C to glutaryl-7-aminocephalosporanic acid
CN1203627A (zh) *	1995-12-07	1998-12-30	诺沃挪第克公司	酶活性的选择性灭活
EP0991752A2 (en) *	1997-09-09	2000-04-12	Biochemie Gesellschaft M.B.H.	Esterase free enzymes
WO2002061068A2 (en) *	2001-01-31	2002-08-08	Novozymes A/S	Oxidase free of catalase side activities
KR100512774B1 (ko) *	2001-10-06	2005-09-07	종근당바이오 주식회사	7-아미노세팔로스포란산의 제조를 위한 세팔로스포린ｃ배양액의 전처리방법
US20090208543A1 (en) *	2008-01-22	2009-08-20	Oral Health Clinical Services	Method and apparatus for applying a protective oral care composition
EP3473715B1 (en) *	2016-06-21	2021-08-04	PHC Holdings Corporation	Catalase inhibitor and method for measuring analyte using catalase inhibitor

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1272769A (en) *	1968-08-02	1972-05-03	Glaxo Lab Ltd	Improvements in or relating to cephalosporin derivatives
GB1385685A (en) *	1971-04-21	1975-02-26	Glaxo Lab Ltd	Cephalosporin derivatives
GB1474519A (da) *	1973-05-14	1977-05-25
US3976546A (en) *	1974-11-08	1976-08-24	Glaxo Laboratories Limited	Cephalosporins
GB1494452A (en) *	1975-01-22	1977-12-07	Asahi Chemical Ind	Process for preparing 7-aminocephalosporanic acid derivatives
US4394450A (en) *	1982-03-01	1983-07-19	Miles Laboratories, Inc.	Method for purification of uricase
DE3447023A1 (de) *	1984-12-22	1986-06-26	Hoechst Ag, 6230 Frankfurt	Neue d-aminosaeure-transaminase und ihre verwendung
ATE129012T1 (de) *	1989-07-19	1995-10-15	Lilly Co Eli	Enzymatische oxidation von ceph c zu glutaryl-7- aminocephalosporansäure.

1990
- 1990-07-16 AT AT90307738T patent/ATE129012T1/de not_active IP Right Cessation
- 1990-07-16 DK DK90307738.6T patent/DK0409521T3/da active
- 1990-07-16 CA CA002268710A patent/CA2268710C/en not_active Expired - Fee Related
- 1990-07-16 ES ES90307738T patent/ES2079442T3/es not_active Expired - Lifetime
- 1990-07-16 CA CA002021299A patent/CA2021299C/en not_active Expired - Fee Related
- 1990-07-16 DE DE69022909T patent/DE69022909T2/de not_active Expired - Fee Related
- 1990-07-16 EP EP90307738A patent/EP0409521B1/en not_active Expired - Lifetime
- 1990-07-16 IL IL9509090A patent/IL95090A/en not_active IP Right Cessation
- 1990-07-16 EP EP94100223A patent/EP0601996A1/en not_active Withdrawn
- 1990-07-18 HU HU904539A patent/HU212587B/hu not_active IP Right Cessation
- 1990-07-18 KR KR1019900010913A patent/KR0163175B1/ko not_active Expired - Fee Related
- 1990-07-18 JP JP2192858A patent/JP2883173B2/ja not_active Expired - Lifetime
- 1990-07-18 IE IE262390A patent/IE71523B1/en not_active IP Right Cessation
1994
- 1994-03-11 US US08/212,656 patent/US5424203A/en not_active Expired - Fee Related
1995
- 1995-02-22 US US08/392,438 patent/US5559006A/en not_active Expired - Fee Related
- 1995-10-12 GR GR950402684T patent/GR3017731T3/el unknown

Also Published As

Publication number	Publication date
HU904539D0 (en)	1990-12-28
EP0409521A2 (en)	1991-01-23
IL95090A (en)	1995-08-31
KR910003114A (ko)	1991-02-26
EP0409521B1 (en)	1995-10-11
DE69022909D1 (de)	1995-11-16
GR3017731T3 (en)	1996-01-31
CA2021299C (en)	1999-08-17
ES2079442T3 (es)	1996-01-16
JPH0353879A (ja)	1991-03-07
KR0163175B1 (ko)	1998-11-16
IE902623A1 (en)	1991-02-27
US5424203A (en)	1995-06-13
EP0409521A3 (en)	1991-09-11
EP0601996A1 (en)	1994-06-15
CA2021299A1 (en)	1991-01-20
IE71523B1 (en)	1997-02-12
HU212587B (en)	1996-08-29
ATE129012T1 (de)	1995-10-15
US5559006A (en)	1996-09-24
IL95090A0 (en)	1991-06-10
DE69022909T2 (de)	1996-04-11
HUT59727A (en)	1992-06-29
CA2268710C (en)	2000-09-26
JP2883173B2 (ja)	1999-04-19

Similar Documents

Publication	Publication Date	Title
DE69119216D1 (de)	1996-06-05	Enzymatisches Verfahren zur Herstellung von 7-Aminocephalosporinsäure und Derivate
DE68925002D1 (de)	1996-01-18	Verfahren zur Herstellung von optisch-aktiven alpha-substituierten organischen Säuren und Mikroorganismen und Enzyme, die dafür verwendet werden.
NO921876L (no)	1992-07-10	Enzymatisk spaltning av endo-bicyklo(2,2.1)heptan-2-ol ogavledede farmasoeytisk midler
DK0535940T3 (da)	1998-04-27	Fremgangsmåde til fremstilling af dihomo-gamma-linolensyre og et lipid indeholdende samme
DE69022909D1 (de)	1995-11-16	Enzymatische Oxidation von Ceph C zu Glutaryl-7-Aminocephalosporansäure.
AU4815885A (en)	1986-04-10	Enzymatic process
DE68906904D1 (de)	1993-07-15	Verfahren zur herstellung von optisch aktiven 2-arylalkansaeuren.
DE59106876D1 (de)	1995-12-21	Verfahren zur enzymatischen Herstellung optisch aktiver Cyanhydrine.
ATE88476T1 (de)	1993-05-15	Verfahren zur herstellung von 7-aca-derivaten.
AU590975B2 (en)	1989-11-23	Production of microorganisims having ice nucleating activity
DK428184A (da)	1985-03-10	2-oxocarbonsyrereduktase, fremgangsmaade til fremstilling heraf samt anvendelse heraf til reduktion af 2-oxocarbonsyrer og disses estere
DE3679149D1 (de)	1991-06-13	Verfahren zur enzymatischen trennung von optisch aktiven isomeren des 2-aminobutanols.
ES521943A0 (es)	1984-08-16	Un procedimiento de produccion de glucosa deshidrogenasa.
IT1208519B (it)	1989-07-10	Procedimento di purificazione di un enzima.
EP0321849A3 (en)	1990-09-12	Method for the enzymatic hydrolysis of alpha-aminoadipinyl monoamino compounds
ATA47694A (de)	1995-12-15	Enzymatisches oxidationsverfahren zur umsetzung von cephalosporin c in glutaryl-7- aminocephalosporansäure
DE3265789D1 (en)	1985-10-03	Enzyme solutions and method for the preparation thereof
ES2055122T3 (es)	1994-08-16	Procedimiento de preparacion de acidos 2-ariloxi- o 2-ariltio-alcanoicos.
AU2163588A (en)	1989-03-09	Stabilization of enzymes by inhibiting proteolytic enzyme contaminants
DK460884A (da)	1985-03-28	Fremgangsmaade til fremstilling af de optiske antipoder af tert.leucin
ATE71406T1 (de)	1992-01-15	Verfahren zur durchfuehrung enzymatischer oxidationen.
DE59304167D1 (de)	1996-11-21	Mikrobiologisches Verfahren zur Herstellung von 5-Hydroxy-2-pyrazincarbonsäure
PH25252A (en)	1991-03-27	Novel microorganism and method for production of glutamic acid using the same
IT8121236A0 (it)	1981-04-16	Processo per la produzione di l-aminoacidi usando microorganismi immobilizzati.
ATE28186T1 (de)	1987-07-15	Alpha-allenyl-alpha-amino carbonsaeuren.