DK0409521T3 - Forbedret enzymatisk oxidation af Ceph C til glutaryl-7-aminocephalosporansyre - Google Patents

Forbedret enzymatisk oxidation af Ceph C til glutaryl-7-aminocephalosporansyre

Info

Publication number: DK0409521T3
Authority: DK; Denmark
Prior art keywords: glutaryl; ceph; enzymatic oxidation; enhanced enzymatic; aminocephalosporanoic acid
Prior art date: 1989-07-19

Application number

DK90307738.6T

Other languages

English (en)

Inventor

Jeffrey Thomas Vicenzi

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-07-19

Filing date

1990-07-16

Publication date

1996-02-05

1990-07-16 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1996-02-05 Application granted granted Critical

1996-02-05 Publication of DK0409521T3 publication Critical patent/DK0409521T3/da

Links

230000002255 enzymatic effect Effects 0.000 title abstract 2
230000003647 oxidation Effects 0.000 title abstract 2
238000007254 oxidation reaction Methods 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
IXUSDMGLUJZNFO-BXUZGUMPSA-N (7R)-7-(4-carboxybutanamido)cephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCCC(O)=O)[C@@H]12 IXUSDMGLUJZNFO-BXUZGUMPSA-N 0.000 abstract 1
108090000371 Esterases Proteins 0.000 abstract 1
230000009849 deactivation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
- C12N9/0024—D-Amino acid oxidase (1.4.3.3)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/99—Enzyme inactivation by chemical treatment

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cephalosporin Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)

DK90307738.6T 1989-07-19 1990-07-16 Forbedret enzymatisk oxidation af Ceph C til glutaryl-7-aminocephalosporansyre DK0409521T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US38250589A	1989-07-19	1989-07-19

Publications (1)

Publication Number	Publication Date
DK0409521T3 true DK0409521T3 (da)	1996-02-05

Family

ID=23509253

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90307738.6T DK0409521T3 (da)	1989-07-19	1990-07-16	Forbedret enzymatisk oxidation af Ceph C til glutaryl-7-aminocephalosporansyre

Country Status (13)

Country	Link
US (2)	US5424203A (da)
EP (2)	EP0601996A1 (da)
JP (1)	JP2883173B2 (da)
KR (1)	KR0163175B1 (da)
AT (1)	ATE129012T1 (da)
CA (2)	CA2268710C (da)
DE (1)	DE69022909T2 (da)
DK (1)	DK0409521T3 (da)
ES (1)	ES2079442T3 (da)
GR (1)	GR3017731T3 (da)
HU (1)	HU212587B (da)
IE (1)	IE71523B1 (da)
IL (1)	IL95090A (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0601996A1 (en) *	1989-07-19	1994-06-15	Eli Lilly And Company	Improved enzymatic oxidation of ceph C to glutaryl-7-amino-cephalosporanic acid
DE4028119C1 (da) *	1990-09-05	1991-12-05	Hoechst Ag, 6230 Frankfurt, De
CA2100987C (en) *	1992-07-27	1999-06-15	Kaoru Furuya	A transformant capable of producing d-amino acid oxidase
EP0600247A3 (de) *	1992-11-05	1995-05-10	Hoechst Ag	Verfahren zur selektiven Desaktivierung von unerwünschten Proteinen in einem Proteingemisch mittels Mikrowelleneinstrahlung.
ES2097080B1 (es) *	1993-03-08	1997-11-16	Asahi Chemical Ind	Procedimiento para la conversion de cefalosporina c en acido glutaril-7-aminocefalosporanico.
AU1092297A (en) *	1995-12-07	1997-06-27	Novo Nordisk A/S	Selective inactivation of enzyme activities
US6465227B1 (en)	1997-09-09	2002-10-15	Biochemie Gesellschaft M.B.H.	Spherical particles containing microorganism cells having enzyme activity
AU2002227889A1 (en) *	2001-01-31	2002-08-12	Novozymes A/S	Oxidase free of catalase side activities
KR100512774B1 (ko) *	2001-10-06	2005-09-07	종근당바이오 주식회사	7-아미노세팔로스포란산의 제조를 위한 세팔로스포린ｃ배양액의 전처리방법
US20090208543A1 (en) *	2008-01-22	2009-08-20	Oral Health Clinical Services	Method and apparatus for applying a protective oral care composition
EP3473715B1 (en) *	2016-06-21	2021-08-04	PHC Holdings Corporation	Catalase inhibitor and method for measuring analyte using catalase inhibitor

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1272769A (en) *	1968-08-02	1972-05-03	Glaxo Lab Ltd	Improvements in or relating to cephalosporin derivatives
GB1385685A (en) *	1971-04-21	1975-02-26	Glaxo Lab Ltd	Cephalosporin derivatives
GB1474519A (da) *	1973-05-14	1977-05-25
US3976546A (en) *	1974-11-08	1976-08-24	Glaxo Laboratories Limited	Cephalosporins
US4079180A (en) *	1975-01-22	1978-03-14	Asahi Kasei Kogyo Kabushiki Kaisha	Process for preparing 7-aminocephalosporanic acid derivatives
US4394450A (en) *	1982-03-01	1983-07-19	Miles Laboratories, Inc.	Method for purification of uricase
DE3447023A1 (de) *	1984-12-22	1986-06-26	Hoechst Ag, 6230 Frankfurt	Neue d-aminosaeure-transaminase und ihre verwendung
EP0601996A1 (en) *	1989-07-19	1994-06-15	Eli Lilly And Company	Improved enzymatic oxidation of ceph C to glutaryl-7-amino-cephalosporanic acid

1990
- 1990-07-16 EP EP94100223A patent/EP0601996A1/en not_active Withdrawn
- 1990-07-16 CA CA002268710A patent/CA2268710C/en not_active Expired - Fee Related
- 1990-07-16 IL IL9509090A patent/IL95090A/en not_active IP Right Cessation
- 1990-07-16 DK DK90307738.6T patent/DK0409521T3/da active
- 1990-07-16 DE DE69022909T patent/DE69022909T2/de not_active Expired - Fee Related
- 1990-07-16 ES ES90307738T patent/ES2079442T3/es not_active Expired - Lifetime
- 1990-07-16 CA CA002021299A patent/CA2021299C/en not_active Expired - Fee Related
- 1990-07-16 AT AT90307738T patent/ATE129012T1/de not_active IP Right Cessation
- 1990-07-16 EP EP90307738A patent/EP0409521B1/en not_active Expired - Lifetime
- 1990-07-18 JP JP2192858A patent/JP2883173B2/ja not_active Expired - Lifetime
- 1990-07-18 KR KR1019900010913A patent/KR0163175B1/ko not_active Expired - Fee Related
- 1990-07-18 HU HU904539A patent/HU212587B/hu not_active IP Right Cessation
- 1990-07-18 IE IE262390A patent/IE71523B1/en not_active IP Right Cessation
1994
- 1994-03-11 US US08/212,656 patent/US5424203A/en not_active Expired - Fee Related
1995
- 1995-02-22 US US08/392,438 patent/US5559006A/en not_active Expired - Fee Related
- 1995-10-12 GR GR950402684T patent/GR3017731T3/el unknown

Also Published As

Publication number	Publication date
KR0163175B1 (ko)	1998-11-16
IE902623A1 (en)	1991-02-27
DE69022909T2 (de)	1996-04-11
EP0601996A1 (en)	1994-06-15
CA2021299C (en)	1999-08-17
US5559006A (en)	1996-09-24
IL95090A0 (en)	1991-06-10
JP2883173B2 (ja)	1999-04-19
IL95090A (en)	1995-08-31
CA2268710C (en)	2000-09-26
ATE129012T1 (de)	1995-10-15
EP0409521B1 (en)	1995-10-11
IE71523B1 (en)	1997-02-12
GR3017731T3 (en)	1996-01-31
US5424203A (en)	1995-06-13
KR910003114A (ko)	1991-02-26
EP0409521A3 (en)	1991-09-11
JPH0353879A (ja)	1991-03-07
DE69022909D1 (de)	1995-11-16
ES2079442T3 (es)	1996-01-16
HUT59727A (en)	1992-06-29
HU212587B (en)	1996-08-29
HU904539D0 (en)	1990-12-28
CA2021299A1 (en)	1991-01-20
EP0409521A2 (en)	1991-01-23

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