ATE88476T1 - Verfahren zur herstellung von 7-aca-derivaten. - Google Patents

Verfahren zur herstellung von 7-aca-derivaten.

Info

Publication number
ATE88476T1
ATE88476T1 AT86810224T AT86810224T ATE88476T1 AT E88476 T1 ATE88476 T1 AT E88476T1 AT 86810224 T AT86810224 T AT 86810224T AT 86810224 T AT86810224 T AT 86810224T AT E88476 T1 ATE88476 T1 AT E88476T1
Authority
AT
Austria
Prior art keywords
production
aca derivatives
derivatives
aca
alkoxymethylcephem
Prior art date
Application number
AT86810224T
Other languages
English (en)
Inventor
Bernhard Christian Prager
Hubert Sturm
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Application granted granted Critical
Publication of ATE88476T1 publication Critical patent/ATE88476T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/187-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT86810224T 1985-06-03 1986-05-23 Verfahren zur herstellung von 7-aca-derivaten. ATE88476T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0166985A AT384222B (de) 1985-06-03 1985-06-03 Verfahren zur herstellung von 7-amino-3alkoxymethyl-3-cephem-4-carbonsaeuren

Publications (1)

Publication Number Publication Date
ATE88476T1 true ATE88476T1 (de) 1993-05-15

Family

ID=3518423

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0166985A AT384222B (de) 1985-06-03 1985-06-03 Verfahren zur herstellung von 7-amino-3alkoxymethyl-3-cephem-4-carbonsaeuren
AT86810224T ATE88476T1 (de) 1985-06-03 1986-05-23 Verfahren zur herstellung von 7-aca-derivaten.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0166985A AT384222B (de) 1985-06-03 1985-06-03 Verfahren zur herstellung von 7-amino-3alkoxymethyl-3-cephem-4-carbonsaeuren

Country Status (15)

Country Link
US (1) US5580978A (de)
EP (1) EP0204657B1 (de)
JP (1) JPH0649704B2 (de)
AT (2) AT384222B (de)
AU (1) AU602124B2 (de)
DE (1) DE3688302T2 (de)
DK (1) DK164060C (de)
ES (1) ES8706693A1 (de)
FI (1) FI86183C (de)
HK (1) HK49796A (de)
IE (1) IE59911B1 (de)
IL (1) IL78983A (de)
NZ (1) NZ216366A (de)
PH (1) PH22895A (de)
ZA (1) ZA864134B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3789412T2 (de) * 1986-10-02 1994-06-30 Asahi Chemical Ind Verfahren zur Herstellung von 3-Alkoxymethylcephalosporinen.
JP2612493B2 (ja) * 1988-05-24 1997-05-21 旭化成工業株式会社 3―置換メチル―3―セフェム―4―カルボン酸類の製造方法
DE4004370A1 (de) * 1990-02-13 1991-08-14 Hoechst Ag Verfahren zur herstellung von 7-amino-3-methoxymethyl-ceph-3-em-4-carbonsaeure
EP0485204B1 (de) 1990-11-07 1995-05-31 Sankyo Company Limited Verfahren zur Herstellung von 3-Alkoxymethyl Cephalosporinderivate
AT401177B (de) * 1993-10-22 1996-07-25 Biochemie Gmbh Verfahren zur herstellung von 7-amino-3-cephem-4-carbonsäure-derivaten
US20030135041A1 (en) * 2002-01-04 2003-07-17 Orchid Chemicals & Pharmaceuticals Limited, India Synthesis of ceftiofur intermediate
EP2758407A1 (de) 2011-09-20 2014-07-30 Dhanuka Laboratories Ltd. Verbessertes verfahren für cefpodoximsäure
EP3426663B1 (de) 2016-03-07 2020-01-29 Dhanuka Laboratories Ltd. Verfahren zur alkylierung der hydroxymethylgruppe an position -3 von cephalosporinen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1241656A (en) * 1967-08-21 1971-08-04 Glaxo Lab Ltd Improvements in or relating to cephalosporin compounds
GB1565941A (en) * 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
HU182411B (en) * 1981-11-03 1984-01-30 Richter Gedeon Vegyeszet Process for preparing eburnamonine derivatives
JPS57192392A (en) * 1981-05-19 1982-11-26 Sankyo Co Ltd Production of 3-alkoxymethylcephalosporin
JPS5896091A (ja) * 1981-12-01 1983-06-07 Sankyo Co Ltd 3−アルコキシメチルセフアロスポリン類の製造法
DE3789412T2 (de) * 1986-10-02 1994-06-30 Asahi Chemical Ind Verfahren zur Herstellung von 3-Alkoxymethylcephalosporinen.

Also Published As

Publication number Publication date
IE861440L (en) 1986-12-03
FI86183B (fi) 1992-04-15
ZA864134B (en) 1988-01-27
DE3688302D1 (de) 1993-05-27
DK259486D0 (da) 1986-06-02
AT384222B (de) 1987-10-12
HK49796A (en) 1996-03-29
US5580978A (en) 1996-12-03
JPH0649704B2 (ja) 1994-06-29
FI862336A7 (fi) 1986-12-04
ES555612A0 (es) 1987-07-01
EP0204657B1 (de) 1993-04-21
DK164060B (da) 1992-05-04
IE59911B1 (en) 1994-04-20
IL78983A0 (en) 1986-09-30
ATA166985A (de) 1987-03-15
EP0204657A2 (de) 1986-12-10
AU602124B2 (en) 1990-10-04
NZ216366A (en) 1989-08-29
AU5824586A (en) 1986-12-11
IL78983A (en) 1991-01-31
PH22895A (en) 1989-01-19
FI862336A0 (fi) 1986-06-02
DE3688302T2 (de) 1993-10-21
DK164060C (da) 1992-09-28
DK259486A (da) 1986-12-04
FI86183C (fi) 1992-07-27
ES8706693A1 (es) 1987-07-01
JPS61289093A (ja) 1986-12-19
EP0204657A3 (en) 1988-08-17

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