DK0412058T3 - 1-Acyl-2-pyrrolidinoner som indlærings- og hukommelsesforstærkende midler og farmaceutiske præparater indeholdende disse forbindelser - Google Patents
1-Acyl-2-pyrrolidinoner som indlærings- og hukommelsesforstærkende midler og farmaceutiske præparater indeholdende disse forbindelserInfo
- Publication number
- DK0412058T3 DK0412058T3 DK90830256.5T DK90830256T DK0412058T3 DK 0412058 T3 DK0412058 T3 DK 0412058T3 DK 90830256 T DK90830256 T DK 90830256T DK 0412058 T3 DK0412058 T3 DK 0412058T3
- Authority
- DK
- Denmark
- Prior art keywords
- pyrrolidinones
- acyl
- learning
- pharmaceutical compositions
- substituted
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000003695 memory enhancer Substances 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- -1 N-substituted pyrrolidin-2-yl Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8948072A IT1231921B (it) | 1989-06-12 | 1989-06-12 | 1-acil-2-pirrolidoni quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0412058T3 true DK0412058T3 (da) | 1994-09-19 |
Family
ID=11264356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90830256.5T DK0412058T3 (da) | 1989-06-12 | 1990-06-08 | 1-Acyl-2-pyrrolidinoner som indlærings- og hukommelsesforstærkende midler og farmaceutiske præparater indeholdende disse forbindelser |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5102896A (da) |
| EP (1) | EP0412058B1 (da) |
| JP (1) | JPH0324054A (da) |
| AT (1) | ATE110363T1 (da) |
| DE (1) | DE69011781T2 (da) |
| DK (1) | DK0412058T3 (da) |
| ES (1) | ES2058874T3 (da) |
| IT (1) | IT1231921B (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1247698B (it) * | 1990-06-21 | 1994-12-30 | Sigma Tau Ind Farmaceuti | 1-alchil-3-(acilammino)-e-caprolattami quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
| IT1249728B (it) * | 1991-11-06 | 1995-03-09 | Sigma Tau Ind Farmaceuti | Derivati delle prolinammide quali attivatori della memoria e dei processi di apprendimento e composizioni farmaceutiche che li contengono |
| EP1367056A1 (en) * | 1992-07-24 | 2003-12-03 | The Regents Of The University Of California | Drugs that enhance synaptic responses mediated by AMPA receptors |
| EP0730631B1 (en) * | 1993-11-25 | 1999-07-07 | WARWICK INTERNATIONAL GROUP LIMITED (Company No. 2982784) | Bleaching compositions |
| CA2165919A1 (en) * | 1994-12-26 | 1996-06-27 | Koichi Katsuyama | Agents for inhibiting the production of il-1.beta. and the release of tnf. |
| CN103910712B (zh) * | 2014-04-02 | 2016-09-07 | 江南大学 | 一种过氧化氢活化剂及其应用 |
| CN104032563B (zh) * | 2014-05-27 | 2016-03-23 | 浙江莱美纺织印染科技有限公司 | 一种涤纶混纺织物漂白前处理方法 |
| US11878971B2 (en) | 2020-12-29 | 2024-01-23 | Huscion Co., Ltd. | Piperlongumine-based compound and immuno regulator comprising the same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CU21107A3 (es) * | 1978-02-10 | 1988-02-01 | Hoffmann La Roche | Pyrrolidines derivatives |
| CA1115212A (en) * | 1978-02-10 | 1981-12-29 | Emilio Kyburz | Pyrrolidine derivatives |
| DE3326724A1 (de) * | 1983-07-25 | 1985-02-07 | Boehringer Ingelheim KG, 6507 Ingelheim | In 1-stellung substituierte 4-hydroxymethyl-pyrrolidinone, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen und zwischenprodukte |
| JPS61229801A (ja) * | 1985-04-03 | 1986-10-14 | Taki Chem Co Ltd | 植物生長調節剤 |
-
1989
- 1989-06-12 IT IT8948072A patent/IT1231921B/it active
-
1990
- 1990-06-08 DK DK90830256.5T patent/DK0412058T3/da active
- 1990-06-08 ES ES90830256T patent/ES2058874T3/es not_active Expired - Lifetime
- 1990-06-08 EP EP90830256A patent/EP0412058B1/en not_active Expired - Lifetime
- 1990-06-08 AT AT90830256T patent/ATE110363T1/de not_active IP Right Cessation
- 1990-06-08 DE DE69011781T patent/DE69011781T2/de not_active Expired - Fee Related
- 1990-06-11 US US07/536,275 patent/US5102896A/en not_active Expired - Fee Related
- 1990-06-11 JP JP2152510A patent/JPH0324054A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US5102896A (en) | 1992-04-07 |
| EP0412058A1 (en) | 1991-02-06 |
| EP0412058B1 (en) | 1994-08-24 |
| JPH0324054A (ja) | 1991-02-01 |
| IT8948072A0 (it) | 1989-06-12 |
| IT1231921B (it) | 1992-01-15 |
| DE69011781T2 (de) | 1995-01-05 |
| DE69011781D1 (de) | 1994-09-29 |
| ES2058874T3 (es) | 1994-11-01 |
| ATE110363T1 (de) | 1994-09-15 |
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