DK0412487T3 - Fremgangsmåde til fremstilling af castanosperminestere - Google Patents

Fremgangsmåde til fremstilling af castanosperminestere

Info

Publication number
DK0412487T3
DK0412487T3 DK90115107.6T DK90115107T DK0412487T3 DK 0412487 T3 DK0412487 T3 DK 0412487T3 DK 90115107 T DK90115107 T DK 90115107T DK 0412487 T3 DK0412487 T3 DK 0412487T3
Authority
DK
Denmark
Prior art keywords
esters
making
castano spermine
castano
spermine
Prior art date
Application number
DK90115107.6T
Other languages
English (en)
Inventor
Alexey L Margolin
Deborah L Delinck
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of DK0412487T3 publication Critical patent/DK0412487T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK90115107.6T 1989-08-08 1990-08-06 Fremgangsmåde til fremstilling af castanosperminestere DK0412487T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/390,794 US4970317A (en) 1989-08-08 1989-08-08 Process for the preparation of castanospermine esters

Publications (1)

Publication Number Publication Date
DK0412487T3 true DK0412487T3 (da) 1995-02-20

Family

ID=23543967

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90115107.6T DK0412487T3 (da) 1989-08-08 1990-08-06 Fremgangsmåde til fremstilling af castanosperminestere

Country Status (15)

Country Link
US (1) US4970317A (da)
EP (1) EP0412487B1 (da)
JP (1) JP3019263B2 (da)
KR (1) KR0167764B1 (da)
AT (1) ATE116371T1 (da)
AU (1) AU624013B2 (da)
CA (1) CA2022576C (da)
DE (1) DE69015499T2 (da)
DK (1) DK0412487T3 (da)
ES (1) ES2068957T3 (da)
GR (1) GR3015396T3 (da)
HU (1) HU209671B (da)
IE (1) IE64971B1 (da)
IL (1) IL95300A (da)
ZA (1) ZA906098B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5066807A (en) * 1990-03-12 1991-11-19 Merrell Dow Pharmaceuticals Inc. Process for the preparation of castanospermine
US5844102A (en) * 1994-07-07 1998-12-01 University Of Maryland Baltimore County Glycohydrolase inhibitors, their preparation and use thereof
GB0110832D0 (en) * 2001-05-03 2001-06-27 Virogen Ltd Antiviral compounds
MX2007003853A (es) * 2004-10-06 2007-11-21 Migenix Inc Composiciones antivirales en combinacion que comprenden castanospermina y metodos de uso.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952585A (en) * 1988-12-15 1990-08-28 Merrell Dow Pharmaceuticals Inc. Castanospermine esters in the inhibition of tumor metastasis

Also Published As

Publication number Publication date
IL95300A (en) 1994-10-21
EP0412487B1 (en) 1994-12-28
EP0412487A2 (en) 1991-02-13
CA2022576A1 (en) 1991-02-09
DE69015499D1 (de) 1995-02-09
IL95300A0 (en) 1991-06-30
ZA906098B (en) 1991-05-29
AU624013B2 (en) 1992-05-28
KR0167764B1 (en) 1999-01-15
EP0412487A3 (en) 1991-05-29
HU209671B (en) 1994-10-28
ATE116371T1 (de) 1995-01-15
HU904925D0 (en) 1991-01-28
JP3019263B2 (ja) 2000-03-13
AU6014590A (en) 1991-02-14
US4970317A (en) 1990-11-13
IE902853A1 (en) 1991-02-27
ES2068957T3 (es) 1995-05-01
DE69015499T2 (de) 1995-05-11
GR3015396T3 (en) 1995-06-30
KR910004618A (ko) 1991-03-29
IE64971B1 (en) 1995-09-20
JPH0377883A (ja) 1991-04-03
HUT57271A (en) 1991-11-28
CA2022576C (en) 2001-05-01

Similar Documents

Publication Publication Date Title
DE3888274D1 (de) Vorrichtung zur intensiven und kontrollierten Herstellung von Mikroorganismen durch Photosynthese.
GR3006204T3 (da)
ATE71794T1 (de) Herstellungsverfahren fuer holz- oder holzartige pflanzen, insbesondere weinreben.
NZ232834A (en) Reproducing coniferous plants by somatic embrogenesis using plant tissue culturing techniques
DK0494665T3 (da) Fremgangsmåde til fremstilling af 6,12-dihydro-6-hydroxy-cannabidiol og anvendelse deraf til fremstilling af transdelta-9-tetrahydrocannabinol
DK0441695T3 (da) Fremgangsmåde til fremstilling af human faktor VIII og analoger af faktor VIII
DK0655454T3 (da) Fremgangsmåde til fremstilling af 2,2-difluorketensilylacetaler og alfa,alfa-difluor-beta-silyloxy-1,3-dioxolan-4-propansyreestere
DK0655192T3 (da) Fremgangsmåde til fremstilling af kartoffelmikroknolde
HUT47150A (en) Process for increasing the nitrogen assimilation of cultivated plants
DK0412487T3 (da) Fremgangsmåde til fremstilling af castanosperminestere
AU568743B2 (en) Pertussis vaccine
ITMI912149A0 (it) Procedimento per produrre l-lisina mediante fermentazione
DK446381A (da) Saccharose-mutase immobiliseret saccharose-mutase og anvendelse heraf til fremstilling af isomaltulose (6-0-alfa-d-glucopyranosidod-fructose).
EP0233733A3 (en) Process for producing n-phthaloyl-p-nitro-l-phenylalanine
ATE207139T1 (de) Verfahren zur herstellung von butantetracarbonsäure
ATE105463T1 (de) Selektionsverfahren, ausgehend von antherenmicrosporen.
ATE81495T1 (de) Verfahren zur herstellung von natriumfluoralkoholaten.
DK0422523T3 (da) Fremgangsmåde til fremstilling af cykliske kulsyreestere
BR9501136A (pt) Processo para a produção de pilocarpina
DK378984A (da) Fremgangsmaade til fremstilling af arphamenin i hoejt udbytte
FR2491920B1 (da)
DK158462C (da) Fremgangsmaade til fremstilling af 3-alkoxy- eller 3,3-dialkoxycarboxylsyreestere
ES2061602T3 (es) Polimeros acrilicos imidizados y procedimiento para su preparacion.
IT8121236A0 (it) Processo per la produzione di l-aminoacidi usando microorganismi immobilizzati.
DE3884922D1 (de) Verfahren zur Herstellung von thermostabilen alpha-Amylasen durch Kultivierung von überproduzierenden Mikroorganismen.