DK0412487T3 - Fremgangsmåde til fremstilling af castanosperminestere - Google Patents

Fremgangsmåde til fremstilling af castanosperminestere

Info

Publication number
DK0412487T3
DK0412487T3 DK90115107.6T DK90115107T DK0412487T3 DK 0412487 T3 DK0412487 T3 DK 0412487T3 DK 90115107 T DK90115107 T DK 90115107T DK 0412487 T3 DK0412487 T3 DK 0412487T3
Authority
DK
Denmark
Prior art keywords
esters
making
castano spermine
castano
spermine
Prior art date
Application number
DK90115107.6T
Other languages
English (en)
Inventor
Alexey L Margolin
Deborah L Delinck
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of DK0412487T3 publication Critical patent/DK0412487T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK90115107.6T 1989-08-08 1990-08-06 Fremgangsmåde til fremstilling af castanosperminestere DK0412487T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/390,794 US4970317A (en) 1989-08-08 1989-08-08 Process for the preparation of castanospermine esters

Publications (1)

Publication Number Publication Date
DK0412487T3 true DK0412487T3 (da) 1995-02-20

Family

ID=23543967

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90115107.6T DK0412487T3 (da) 1989-08-08 1990-08-06 Fremgangsmåde til fremstilling af castanosperminestere

Country Status (15)

Country Link
US (1) US4970317A (da)
EP (1) EP0412487B1 (da)
JP (1) JP3019263B2 (da)
KR (1) KR0167764B1 (da)
AT (1) ATE116371T1 (da)
AU (1) AU624013B2 (da)
CA (1) CA2022576C (da)
DE (1) DE69015499T2 (da)
DK (1) DK0412487T3 (da)
ES (1) ES2068957T3 (da)
GR (1) GR3015396T3 (da)
HU (1) HU209671B (da)
IE (1) IE64971B1 (da)
IL (1) IL95300A (da)
ZA (1) ZA906098B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5066807A (en) * 1990-03-12 1991-11-19 Merrell Dow Pharmaceuticals Inc. Process for the preparation of castanospermine
US5844102A (en) * 1994-07-07 1998-12-01 University Of Maryland Baltimore County Glycohydrolase inhibitors, their preparation and use thereof
GB0110832D0 (en) * 2001-05-03 2001-06-27 Virogen Ltd Antiviral compounds
JP2008515816A (ja) * 2004-10-06 2008-05-15 ミジェニックス インコーポレイテッド カスタノスペルミンを含有する、併用抗ウイルス組成物およびその使用方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952585A (en) * 1988-12-15 1990-08-28 Merrell Dow Pharmaceuticals Inc. Castanospermine esters in the inhibition of tumor metastasis

Also Published As

Publication number Publication date
ATE116371T1 (de) 1995-01-15
ZA906098B (en) 1991-05-29
ES2068957T3 (es) 1995-05-01
EP0412487A3 (en) 1991-05-29
IE902853A1 (en) 1991-02-27
CA2022576C (en) 2001-05-01
HU904925D0 (en) 1991-01-28
JP3019263B2 (ja) 2000-03-13
HUT57271A (en) 1991-11-28
DE69015499T2 (de) 1995-05-11
EP0412487A2 (en) 1991-02-13
EP0412487B1 (en) 1994-12-28
AU6014590A (en) 1991-02-14
US4970317A (en) 1990-11-13
CA2022576A1 (en) 1991-02-09
JPH0377883A (ja) 1991-04-03
KR0167764B1 (en) 1999-01-15
KR910004618A (ko) 1991-03-29
GR3015396T3 (en) 1995-06-30
IL95300A (en) 1994-10-21
IL95300A0 (en) 1991-06-30
IE64971B1 (en) 1995-09-20
HU209671B (en) 1994-10-28
DE69015499D1 (de) 1995-02-09
AU624013B2 (en) 1992-05-28

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