DK0426395T3 - - Google Patents

Info

Publication number: DK0426395T3
Authority: DK; Denmark
Prior art keywords: assay procedure; range; endotoxin; substantial improvement; previously available
Prior art date: 1989-10-30

Application number

DK90311771.1T

Other languages

Danish (da)

English (en)

Inventor

Ronald N Berzofsky

Original Assignee

Biowhittaker Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-30

Filing date

1990-10-26

Publication date

1997-03-03

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23698313&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0426395(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-10-26 Application filed by Biowhittaker Inc filed Critical Biowhittaker Inc

1997-03-03 Application granted granted Critical

1997-03-03 Publication of DK0426395T3 publication Critical patent/DK0426395T3/da

Links

238000003556 assay Methods 0.000 abstract 3
238000000034 method Methods 0.000 abstract 3
239000002158 endotoxin Substances 0.000 abstract 2
239000012480 LAL reagent Substances 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
239000003593 chromogenic compound Substances 0.000 abstract 1
238000003367 kinetic assay Methods 0.000 abstract 1
238000005259 measurement Methods 0.000 abstract 1
230000035945 sensitivity Effects 0.000 abstract 1
239000000758 substrate Substances 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
- C12Q2337/10—Anilides
- C12Q2337/12—Para-Nitroanilides p-NA
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Zoology (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Microbiology (AREA)
Urology & Nephrology (AREA)
Analytical Chemistry (AREA)
Wood Science & Technology (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
General Engineering & Computer Science (AREA)
Cell Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

DK90311771.1T 1989-10-30 1990-10-26 DK0426395T3 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US42830089A	1989-10-30	1989-10-30

Publications (1)

Publication Number	Publication Date
DK0426395T3 true DK0426395T3 (de)	1997-03-03

Family

ID=23698313

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90311771.1T DK0426395T3 (de)	1989-10-30	1990-10-26

Country Status (10)

Country	Link
US (1)	US5310657A (de)
EP (1)	EP0426395B1 (de)
JP (1)	JP2955345B2 (de)
AT (1)	ATE148230T1 (de)
AU (1)	AU644109B2 (de)
CA (1)	CA2028789C (de)
DE (1)	DE69029785T2 (de)
DK (1)	DK0426395T3 (de)
ES (1)	ES2098256T3 (de)
GR (1)	GR3023298T3 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0549102B1 (de) *	1991-12-25	1996-07-03	Maruha Corporation	Reagenzien und Verfahren zur Bestimmung von Beta-Glucanen
JP3242733B2 (ja) *	1993-02-26	2001-12-25	生化学工業株式会社	エンドトキシン特異的測定剤
US6270982B1 (en)	1997-10-09	2001-08-07	Charles River Laboratories	Methods and compositions for the detection of bacterial endotoxins
JP4235279B2 (ja) *	1998-04-10	2009-03-11	生化学工業株式会社	新規酵素反応測定法
US20050244299A1 (en) *	2002-04-30	2005-11-03	Biowittaker Technologies Inc	Automated sequential injection analysis systems for the determination of trace endotoxin levels
AU2003300356A1 (en) *	2002-12-20	2004-07-22	The Charlotte-Mecklenburg Hospital Authority	Disposable hand-held device for collection of exhaled breath condensate
US7547285B2 (en) *	2003-02-14	2009-06-16	The Charlotte-Mecklenburg Hospital Authority	Device and method for collection of exhaled alveolar breath condensate
US7828741B2 (en) *	2002-12-20	2010-11-09	The Charlotte-Mecklenburg Hospital Authority	Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia
ATE452986T1 (de)	2003-03-17	2010-01-15	Charles River Lab Inc	Methoden und zusammensetzungen für den nachweis mikrobieller verunreinigungen
US20050048655A1 (en) *	2003-04-18	2005-03-03	Novitsky Thomas J.	Kit for detecting endotoxin
US20050026239A1 (en) *	2003-04-18	2005-02-03	Associates Of Cape Cod, Inc.	Kit for detecting endotoxin in aqueous solutions
BRPI0407929A (pt) *	2003-11-07	2006-02-21	Cambrex Bio Science Walkersvil	aparelho em linha e método para determinação de nìveis de endotoxina
JP2008522640A (ja) *	2004-12-02	2008-07-03	チャールズリバーラボラトリーズ，インコーポレイテッド	グラム陽性菌夾雑物の検出および／または定量化のための方法ならびに組成物
EP1836492B1 (de)	2005-01-13	2008-12-31	Charles River Laboratories, Inc.	Verfahren zur klassifizierung von mikroben in einer biologischen probe
EP2050820A4 (de)	2006-07-07	2009-12-16	Seikagaku Kogyo Co Ltd	Progerinnungsenzym und verfahren zum nachweis von endotoxin oder (1 3)- -d-glucan unter verwendung davon
US20080124248A1 (en) *	2006-11-29	2008-05-29	Edward Andrew Sobek	Endotoxins and glucans quantification in indoor air
US20090286692A1 (en) *	2008-04-15	2009-11-19	Wainwright Norman R	Cartridge and Method for Sample Analysis
JP5489680B2 (ja) *	2009-12-02	2014-05-14	興和株式会社	生物由来の生理活性物質の測定方法、それを実行するためのプログラム及び、生物由来の生理活性物質の測定装置
CA2755276A1 (en)	2009-03-13	2010-09-16	Kowa Company, Ltd.	Method for measuring physiologically active substance of biological origin, program for implementing the same, and apparatus for measuring physiologically active substance of biological origin
JP5981338B2 (ja)	2009-06-26	2016-08-31	チャールズリバーラボラトリーズ，インコーポレイテッド	加熱処理したリムルスアメーバ様細胞溶解物
GB2477752A (en) *	2010-02-11	2011-08-17	Arab Biotechnology Company	Detection of bacteria
CU24073B1 (es)	2011-12-27	2015-01-29	Ct De Investigación Y Desarrollo De Medicamentos Cidem	COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS
US20130078665A1 (en) *	2012-07-18	2013-03-28	Deepika Bodapati	Test strip, a test kit and a method for detection of endotoxin in food
CA2886777C (en)	2012-10-08	2021-07-13	General Electric Company	Preloaded test substrates for testing lal-reactive substances, methods of use, and methods of making
US10309947B2 (en)	2013-02-27	2019-06-04	Trace-Ability, Inc.	System and method for radiosynthesis, quality control and dose dispensing
US10895563B2 (en)	2014-02-26	2021-01-19	Trace-Ability, Inc.	Palette-based systems for analyte characterization
US11002717B2 (en)	2014-02-26	2021-05-11	Trace-Ability, Inc.	Systems and methods for characterizing radioactive analytes
JP7044222B2 (ja) *	2016-08-03	2022-03-30	ロンザウォーカーズヴィル，インコーポレーテッド	実質的にコアギュローゲンを含まないリムルスアメボサイトライセートを使用してエンドトキシンを検出する方法
JP7507560B2 (ja)	2017-01-11	2024-06-28	ロンザウォーカーズヴィル，インコーポレーテッド	コアギュローゲンを含まない、清澄化リムルスアメボサイトライセート
SG11201912888TA (en)	2017-06-28	2020-01-30	Lonza Walkersville Inc	Cartridge for endotoxin detection
US11892397B2 (en) *	2017-10-17	2024-02-06	Board Of Regents, The University Of Texas System	Endotoxin testing assay and method of same
CN109387637A (zh) *	2018-10-12	2019-02-26	四川升和药业股份有限公司	丹参注射液细菌内毒素检测方法
CN111077307B (zh) *	2018-10-21	2022-08-23	厦门鲎试剂生物科技股份有限公司	一种用革兰氏阴性细菌感染快速检测脓毒病的新方法
US12158471B2 (en)	2022-02-11	2024-12-03	Charles River Laboratories, Inc.	Recombinant amebocyte lysate and uses thereof
KR20260021702A (ko)	2023-06-05	2026-02-13	찰스리버레보레토리스,인코포레이티드	재조합 아메보사이트 응고 인자 및 그의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5415797A (en) *	1977-06-14	1979-02-05	Seikagaku Kogyo Co Ltd	Detection and measurement of toxin in cells
US4322217A (en) *	1980-06-27	1982-03-30	Mallinckrodt, Inc.	Process for preparing Limulus lysate
US4510241A (en) *	1981-09-03	1985-04-09	Mallinckrodt, Inc.	Peptide-type substrates useful in the quantitative determination of endotoxin
US4406832A (en) *	1981-09-03	1983-09-27	Mallinckrodt, Inc.	Peptide-type substrates useful in the quantitative determination of endotoxin
DE3439761A1 (de) *	1984-10-31	1986-05-07	Klaus-Peter 6800 Mannheim Becker	Verfahren zur bestimmung von endotoxinkonzentrationen

1990
- 1990-10-26 AT AT90311771T patent/ATE148230T1/de not_active IP Right Cessation
- 1990-10-26 EP EP90311771A patent/EP0426395B1/de not_active Expired - Lifetime
- 1990-10-26 DE DE69029785T patent/DE69029785T2/de not_active Expired - Lifetime
- 1990-10-26 DK DK90311771.1T patent/DK0426395T3/da active
- 1990-10-26 ES ES90311771T patent/ES2098256T3/es not_active Expired - Lifetime
- 1990-10-29 CA CA002028789A patent/CA2028789C/en not_active Expired - Lifetime
- 1990-10-29 AU AU65556/90A patent/AU644109B2/en not_active Expired
- 1990-10-30 JP JP2295164A patent/JP2955345B2/ja not_active Expired - Lifetime
1992
- 1992-07-13 US US07/911,375 patent/US5310657A/en not_active Expired - Lifetime
1997
- 1997-04-08 GR GR970400118T patent/GR3023298T3/el unknown

Also Published As

Publication number	Publication date
DE69029785D1 (de)	1997-03-06
EP0426395A1 (de)	1991-05-08
JPH03220456A (ja)	1991-09-27
GR3023298T3 (en)	1997-07-30
AU6555690A (en)	1991-05-02
EP0426395B1 (de)	1997-01-22
AU644109B2 (en)	1993-12-02
CA2028789C (en)	2001-02-06
ATE148230T1 (de)	1997-02-15
DE69029785T2 (de)	1997-05-28
CA2028789A1 (en)	1991-05-01
ES2098256T3 (es)	1997-05-01
US5310657A (en)	1994-05-10
JP2955345B2 (ja)	1999-10-04

Publication	Publication Date	Title
DK0426395T3 (de)	1997-03-03
ES2148225T3 (es)	2000-10-16	Reactivos y procedimientos que permiten la deteccion y la cuantificacion de la tiroxina en muestras de fluido.
DE69419053D1 (de)	1999-07-22	Reagenz zur Messung von unreifen Leukozyten
ES2188654T3 (es)	2003-07-01	Nuevos esteres de acridinio hidrofilos funcionalizados.
DE3366738D1 (en)	1986-11-13	Enzyme chromatographic immunoassay
ITMI942083A0 (it)	1994-10-12	Strumento diagnostico automatizzato in particolare per l'analisi di campioni in pacchi di prova per un analita
CA2032907A1 (en)	1991-06-23	Hepatitis c assay
CA2096495A1 (en)	1993-12-17	Dual analyte immunoassay
ZA898290B (en)	1991-06-26	Electrochemiluminescent assays
FI915150A7 (fi)	1991-10-31	Menetelmät, reagenssit ja testikäyttöpakkaukset biologisten yksiköiden alapopulaatioiden määrittämiseksi
IL78782A0 (en)	1986-08-31	Method and test kit for competitive enzyme-linked immunosorbent assay for the detection of antibodies
FR2651580B1 (fr)	1991-12-13	Dispositif de caracterisation dielectrique d'echantillons de materiau de surface plane ou non plane et application au controle non destructif de l'homogeneite dielectrique desdits echantillons.
IL74303A (en)	1989-06-30	Compositions and test device for determining the presence of leukocytes,esterase and protease in biological samples
EP0108633A3 (en)	1986-02-12	Assay for qualitatively and/or quantitatively measuring hlh or hcg body fluids and reagents therefor
CA2032053A1 (en)	1991-06-16	Method for quantitation of calcium and magnesium
GR3034288T3 (en)	2000-12-29	Method of stabilizing enzyme conjugates.
DE69031912D1 (de)	1998-02-12	Reagenziensatz für immunoassay
CA2110049A1 (en)	1992-12-10	Devices for performing ion-capture binding assays
IL103821A0 (en)	1993-04-04	Colorimetric methods and reagents for the assay of calcium in a test sample
ES2070129T3 (es)	1995-06-01	Ensayo de aglutinacion.
AU3106589A (en)	1989-09-14	Agent, for immunochemical assays, containing amine oxides
FI910326A7 (fi)	1991-07-23	Tuote, testireagenssisarja ja kerrosmääritysmenetelmä bacteroides intermedius-, bacteroides gingivalis- tai actinobacillus actinomycetemcomitans -bakteerien havaitsemiseksi
DE69526056D1 (de)	2002-05-02	Immunologisches Testverfahren zur Quantifizierung von PEG-modifiziertem humanem Granulozyten-Kolonie-Stimulierender-Faktor
EP0407605A4 (en)	1993-03-10	Reagent for detecting antibody corresponding to acid-fast bacterium antigen and application thereof
ES2169211T3 (es)	2002-07-01	Ensayos de proteccion de micelas.