PT95735A - Processo para a preparacao de morfolinois e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de morfolinois e de composicoes farmaceuticas que os contem

Info

Publication number: PT95735A
Authority: PT; Portugal
Prior art keywords: morfolines; preparation; pharmaceutical compositions; compositions containing; carbon atoms
Prior art date: 1989-10-31

Application number

PT95735A

Other languages

English (en)

Other versions

PT95735B (pt

Inventor

Barrett Randolph Cooper

James Leroy Kelley

David Lee Musso

Grady Evan Boswell

Original Assignee

Wellcome Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-31

Filing date

1990-10-30

Publication date

1991-09-13

1990-10-30 Application filed by Wellcome Found filed Critical Wellcome Found

1991-09-13 Publication of PT95735A publication Critical patent/PT95735A/pt

1998-01-30 Publication of PT95735B publication Critical patent/PT95735B/pt

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 3
125000000753 cycloalkyl group Chemical group 0.000 abstract 2
OURXRFYZEOUCRM-UHFFFAOYSA-N 4-hydroxymorpholine Chemical class ON1CCOCC1 OURXRFYZEOUCRM-UHFFFAOYSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
208000020016 psychiatric disease Diseases 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Psychiatry (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PT95735A 1989-10-31 1990-10-30 Processo para a preparacao de morfolinois e de composicoes farmaceuticas que os contem PT95735B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898924528A GB8924528D0 (en)	1989-10-31	1989-10-31	Heterocyclic pharmaceutical compounds,preparation and use

Publications (2)

Publication Number	Publication Date
PT95735A true PT95735A (pt)	1991-09-13
PT95735B PT95735B (pt)	1998-01-30

Family

ID=10665482

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT95735A PT95735B (pt)	1989-10-31	1990-10-30	Processo para a preparacao de morfolinois e de composicoes farmaceuticas que os contem

Country Status (19)

Country	Link
US (1)	US5104870A (pt)
EP (1)	EP0426416B1 (pt)
JP (1)	JP2873076B2 (pt)
AT (1)	ATE101604T1 (pt)
AU (1)	AU645763B2 (pt)
CA (1)	CA2028893C (pt)
DE (1)	DE69006682T2 (pt)
DK (1)	DK0426416T3 (pt)
ES (1)	ES2062406T3 (pt)
FI (1)	FI94753C (pt)
GB (1)	GB8924528D0 (pt)
HU (2)	HU207304B (pt)
IE (1)	IE66115B1 (pt)
LV (1)	LV11030B (pt)
MX (1)	MX9203219A (pt)
NZ (1)	NZ235882A (pt)
PT (1)	PT95735B (pt)
SG (1)	SG28347G (pt)
ZA (1)	ZA908696B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9108629D0 (en) *	1991-04-23	1991-06-12	Wellcome Found	Heterocyclic pharmaceutical compounds,preparation and use
AU1403899A (en) *	1997-11-14	1999-06-07	Glaxo Group Limited	Method of treating addiction to nicotine products
MA26693A1 (fr) *	1998-09-28	2004-12-20	Glaxo Group Ltd	Compositions pour administration par voie buccale
AU7750100A (en) *	1999-10-13	2001-04-23	Glaxo Group Limited	Method for the treatment of obesity
IL163666A0 (en)	2002-02-22	2005-12-18	New River Pharmaceuticals Inc	Active agent delivery systems and methods for protecting and administering active agents
EP1968603A4 (en) *	2006-01-03	2013-01-16	Algebra Inc	THERAPEUTIC AMINARYLSULFONAMIDE CONJUGATE COMPOUNDS
WO2010121022A1 (en)	2009-04-15	2010-10-21	Research Triangle Institute	Monoamine reuptake inhibitors
CA2800219C (en) *	2010-05-21	2019-03-12	Research Triangle Institute	1 - phenylmorpholine derivatives as hydroxybupropion analogues for treating drug dependence
EP2571858B1 (en)	2010-05-21	2018-06-20	Research Triangle Institute	Phenylmorpholines and analogues thereof
CN105949142B (zh) *	2016-05-21	2018-03-27	南华大学	具有抗抑郁活性的单一手性化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3117967A (en) *	1962-04-02	1964-01-14	Smith Kline French Lab	2-biphenylyl-2-hydroxy-morpholinium halides
FR2553413B1 (fr) *	1983-10-17	1986-03-21	Lafon Labor	Derives de 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine, procede de preparation et utilisation en therapeutique
GB8417170D0 (en) *	1984-07-05	1984-08-08	Wellcome Found	Heterocyclic pharmaceutical compounds

1989
- 1989-10-31 GB GB898924528A patent/GB8924528D0/en active Pending
1990
- 1990-10-30 DK DK90311851.1T patent/DK0426416T3/da active
- 1990-10-30 HU HU906935A patent/HU207304B/hu not_active IP Right Cessation
- 1990-10-30 FI FI905356A patent/FI94753C/fi not_active IP Right Cessation
- 1990-10-30 SG SG1995904223A patent/SG28347G/en unknown
- 1990-10-30 NZ NZ235882A patent/NZ235882A/xx unknown
- 1990-10-30 CA CA002028893A patent/CA2028893C/en not_active Expired - Fee Related
- 1990-10-30 IE IE388890A patent/IE66115B1/en not_active IP Right Cessation
- 1990-10-30 PT PT95735A patent/PT95735B/pt not_active IP Right Cessation
- 1990-10-30 EP EP90311851A patent/EP0426416B1/en not_active Expired - Lifetime
- 1990-10-30 AU AU65639/90A patent/AU645763B2/en not_active Ceased
- 1990-10-30 AT AT90311851T patent/ATE101604T1/de not_active IP Right Cessation
- 1990-10-30 ZA ZA908696A patent/ZA908696B/xx unknown
- 1990-10-30 JP JP2293476A patent/JP2873076B2/ja not_active Expired - Fee Related
- 1990-10-30 ES ES90311851T patent/ES2062406T3/es not_active Expired - Lifetime
- 1990-10-30 DE DE69006682T patent/DE69006682T2/de not_active Expired - Fee Related
1991
- 1991-04-02 US US07/680,637 patent/US5104870A/en not_active Expired - Lifetime
1992
- 1992-06-24 MX MX9203219A patent/MX9203219A/es unknown
1995
- 1995-02-09 LV LVP-95-27A patent/LV11030B/en unknown
- 1995-05-09 HU HU95P/P00125P patent/HU211304A9/hu unknown

Also Published As

Publication number	Publication date
ZA908696B (en)	1992-07-29
EP0426416A1 (en)	1991-05-08
DE69006682T2 (de)	1994-08-04
HU906935D0 (en)	1991-05-28
ES2062406T3 (es)	1994-12-16
AU6563990A (en)	1991-05-09
SG28347G (en)	1995-09-18
HUT57748A (en)	1991-12-30
FI94753B (fi)	1995-07-14
HU207304B (en)	1993-03-29
FI905356A0 (fi)	1990-10-30
AU645763B2 (en)	1994-01-27
CA2028893C (en)	2000-10-10
US5104870A (en)	1992-04-14
LV11030A (lv)	1996-02-20
NZ235882A (en)	1993-05-26
FI94753C (fi)	1995-10-25
LV11030B (en)	1996-08-20
CA2028893A1 (en)	1991-05-01
IE903888A1 (en)	1991-05-08
MX9203219A (es)	1992-07-01
GB8924528D0 (en)	1989-12-20
ATE101604T1 (de)	1994-03-15
JPH03206084A (ja)	1991-09-09
DK0426416T3 (da)	1994-03-14
PT95735B (pt)	1998-01-30
JP2873076B2 (ja)	1999-03-24
EP0426416B1 (en)	1994-02-16
IE66115B1 (en)	1995-12-13
DE69006682D1 (de)	1994-03-24
HU211304A9 (en)	1995-11-28

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Legal Events

Date

Code

Title

Description

1991-09-13

BB1A

Laying open of patent application

Effective date: 19910403

1998-01-30

FG3A

Patent granted, date of granting

Effective date: 19971022

2005-06-30

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20050422