DK0432504T3 - Fremgangsmåde til fremstilling af 1-(aminomethyl)-cyclohexaneddikesyre - Google Patents

Fremgangsmåde til fremstilling af 1-(aminomethyl)-cyclohexaneddikesyre

Info

Publication number
DK0432504T3
DK0432504T3 DK90121827.1T DK90121827T DK0432504T3 DK 0432504 T3 DK0432504 T3 DK 0432504T3 DK 90121827 T DK90121827 T DK 90121827T DK 0432504 T3 DK0432504 T3 DK 0432504T3
Authority
DK
Denmark
Prior art keywords
cyanocyclohexyl
aminomethyl
preparation
acetic acid
cyclohexane acetic
Prior art date
Application number
DK90121827.1T
Other languages
English (en)
Inventor
Hans Peter Dr Mettler
Felix Dr Previdoli
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Application granted granted Critical
Publication of DK0432504T3 publication Critical patent/DK0432504T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
DK90121827.1T 1989-11-16 1990-11-14 Fremgangsmåde til fremstilling af 1-(aminomethyl)-cyclohexaneddikesyre DK0432504T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH412889 1989-11-16

Publications (1)

Publication Number Publication Date
DK0432504T3 true DK0432504T3 (da) 1994-07-04

Family

ID=4270351

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90121827.1T DK0432504T3 (da) 1989-11-16 1990-11-14 Fremgangsmåde til fremstilling af 1-(aminomethyl)-cyclohexaneddikesyre

Country Status (14)

Country Link
US (2) US5095148A (da)
EP (1) EP0432504B1 (da)
JP (1) JPH03176459A (da)
AT (1) ATE106861T1 (da)
CA (1) CA2030107A1 (da)
DE (1) DE59006037D1 (da)
DK (1) DK0432504T3 (da)
ES (1) ES2057334T3 (da)
FI (1) FI905584A7 (da)
IL (1) IL96360A0 (da)
NO (1) NO177531C (da)
PT (1) PT95894B (da)
RU (1) RU2029761C1 (da)
YU (1) YU215290A (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA49011C2 (uk) * 1996-03-14 2002-09-16 Варнер-Ламберт Компані Похідні циклічної амінокислоти, фармацевтична композиція та спосіб лікування
US6372792B1 (en) 1996-04-26 2002-04-16 Guy Chouinard Method for treating anxiety, anxiety disorders and insomnia
US6255526B1 (en) 1996-12-24 2001-07-03 Teva Pharmaceutical Industries Ltd. Preparation of gabapentin
WO1999018063A2 (en) 1997-10-07 1999-04-15 Warner-Lambert Company Process for preparing a cyclic amino acid anticonvulsant compound
HU225502B1 (en) * 1998-12-29 2007-01-29 Richter Gedeon Vegyeszet Process for producing 1-(amino-metyl)-cyclohexene-acetic-acid and intermediates
CN1447684A (zh) * 2000-06-16 2003-10-08 特瓦制药工业有限公司 具有在可控制范围内的pH值的稳定的加巴喷丁
IT1319674B1 (it) * 2000-12-01 2003-10-23 Erregierre Spa Processo per la preparazione dell'acido1-(aminometil)cicloesanacetico.
WO2003089403A1 (en) * 2002-04-16 2003-10-30 Taro Pharmaceutical Industries Ltd. Process for preparing gabapentin
ITMI20022071A1 (it) * 2002-10-01 2004-04-02 Erregierre Spa Processo di sintesi dell'acido 1-(aminometil)cicloesanacetico cloridato.
CA2472815A1 (en) 2002-11-18 2004-06-03 Nicholas Piramal India Limited Improved process for preparation of gabapentin
DE602004017166D1 (de) * 2003-03-25 2008-11-27 Kiel Lab Inc Gabapentintannat in flüssigen und/oder halbfesten dosierformen
WO2004093866A1 (en) * 2003-03-25 2004-11-04 Kiel Laboratories, Inc. Process for preparing phenolic acid salts of gabapentin
EP1622603A4 (en) 2003-03-25 2010-03-24 Kiel Lab Inc GABAPENTINIC PHENOLIC ACID SALTS IN SOLID DOSAGE FORMS AND METHODS OF USE
US7439387B2 (en) * 2003-04-21 2008-10-21 Matrix Laboratories Ltd. Process for the preparation of Gabapentin form-II
US20050187295A1 (en) * 2004-02-19 2005-08-25 Surendra Kalyan Processes for the preparation of gabapentin
GB0416228D0 (en) 2004-07-20 2004-08-25 Sandoz Ind Products S A Process for the preparation of gabapentin
JP5144656B2 (ja) * 2006-06-30 2013-02-13 ザック システム エス．ピー．エー． ガバペンチンの調製プロセス
CN101585778B (zh) * 2008-05-19 2014-08-13 上海臣邦医药科技有限公司 一种普瑞巴林制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2264354A (en) * 1937-12-22 1941-12-02 Ig Farbenindustrie Ag Addition products of dienes and unsaturated esters, ketones, or nitriles
US2467927A (en) * 1947-05-29 1949-04-19 Goodrich Co B F Preparation of monomeric alkyl alpha-cyano-acrylates
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2611690A1 (de) * 1976-03-19 1977-09-22 Goedecke Ag Cyclische sulfonyloxyimide
YU162789A (en) * 1988-09-01 1990-12-31 Lonza Ag 2-aza-4-(alcoxycarbonyl) spiro/4,5/decan-3-ones
PH27359A (en) * 1989-08-25 1993-06-21 Warner Lambert Co Process for cyclic amino acid anticonvulsant compounds

Also Published As

Publication number Publication date
FI905584L (fi) 1991-05-17
NO904953D0 (no) 1990-11-15
FI905584A0 (fi) 1990-11-12
JPH03176459A (ja) 1991-07-31
FI905584A7 (fi) 1991-05-17
EP0432504A1 (de) 1991-06-19
PT95894B (pt) 1998-01-30
US5095148A (en) 1992-03-10
RU2029761C1 (ru) 1995-02-27
YU215290A (sh) 1993-05-28
NO904953L (no) 1991-05-21
EP0432504B1 (de) 1994-06-08
PT95894A (pt) 1991-09-13
NO177531C (no) 1995-10-04
ATE106861T1 (de) 1994-06-15
CA2030107A1 (en) 1991-05-17
DE59006037D1 (de) 1994-07-14
NO177531B (no) 1995-06-26
ES2057334T3 (es) 1994-10-16
IL96360A0 (en) 1991-08-16
US5130455A (en) 1992-07-14

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