PT95894A - Processo para a producao de acido 1-(aminometil)-ciclo-hexano-acetico e dos seus intermediarios - Google Patents

Processo para a producao de acido 1-(aminometil)-ciclo-hexano-acetico e dos seus intermediarios

Info

Publication number
PT95894A
PT95894A PT95894A PT9589490A PT95894A PT 95894 A PT95894 A PT 95894A PT 95894 A PT95894 A PT 95894A PT 9589490 A PT9589490 A PT 9589490A PT 95894 A PT95894 A PT 95894A
Authority
PT
Portugal
Prior art keywords
cyanocyclohexyl
aminomethyl
intermediaries
cyclohexane
production
Prior art date
Application number
PT95894A
Other languages
English (en)
Other versions
PT95894B (pt
Inventor
Hans Peter Mettler
Felix Previdoli
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of PT95894A publication Critical patent/PT95894A/pt
Publication of PT95894B publication Critical patent/PT95894B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PT95894A 1989-11-16 1990-11-15 Processo para a producao de acido 1-(aminometil)-ciclo-hexano-acetico e dos seus intermediarios PT95894B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH412889 1989-11-16

Publications (2)

Publication Number Publication Date
PT95894A true PT95894A (pt) 1991-09-13
PT95894B PT95894B (pt) 1998-01-30

Family

ID=4270351

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95894A PT95894B (pt) 1989-11-16 1990-11-15 Processo para a producao de acido 1-(aminometil)-ciclo-hexano-acetico e dos seus intermediarios

Country Status (14)

Country Link
US (2) US5095148A (pt)
EP (1) EP0432504B1 (pt)
JP (1) JPH03176459A (pt)
AT (1) ATE106861T1 (pt)
CA (1) CA2030107A1 (pt)
DE (1) DE59006037D1 (pt)
DK (1) DK0432504T3 (pt)
ES (1) ES2057334T3 (pt)
FI (1) FI905584L (pt)
IL (1) IL96360A0 (pt)
NO (1) NO177531C (pt)
PT (1) PT95894B (pt)
RU (1) RU2029761C1 (pt)
YU (1) YU215290A (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU224720B1 (en) * 1996-03-14 2006-01-30 Warner Lambert Co Novel substituted cyclic amino acid derivatives use as pharmaceutical agents
US6372792B1 (en) 1996-04-26 2002-04-16 Guy Chouinard Method for treating anxiety, anxiety disorders and insomnia
US6255526B1 (en) 1996-12-24 2001-07-03 Teva Pharmaceutical Industries Ltd. Preparation of gabapentin
WO1999018063A2 (en) 1997-10-07 1999-04-15 Warner-Lambert Company Process for preparing a cyclic amino acid anticonvulsant compound
HU225502B1 (en) * 1998-12-29 2007-01-29 Richter Gedeon Vegyeszet Process for producing 1-(amino-metyl)-cyclohexene-acetic-acid and intermediates
PL363155A1 (en) * 2000-06-16 2004-11-15 Teva Pharmaceutical Industries, Ltd. Stable gabapentin having ph within a controlled range
IT1319674B1 (it) * 2000-12-01 2003-10-23 Erregierre Spa Processo per la preparazione dell'acido1-(aminometil)cicloesanacetico.
CA2478471A1 (en) * 2002-04-16 2003-10-30 Taro Pharmaceutical Industries Ltd. Process for preparing gabapentin
ITMI20022071A1 (it) * 2002-10-01 2004-04-02 Erregierre Spa Processo di sintesi dell'acido 1-(aminometil)cicloesanacetico cloridato.
EP1727784B1 (en) 2002-11-18 2008-12-24 Nicholas Piramal India Limited Improved process for preparation of gabapentin
WO2004093867A2 (en) * 2003-03-25 2004-11-04 Kiel Laboratories, Inc. Phenolic acid salts of gabapentin in liquid and/or semi-solid dosage forms and methods of use
WO2004093866A1 (en) * 2003-03-25 2004-11-04 Kiel Laboratories, Inc. Process for preparing phenolic acid salts of gabapentin
EP1622603A4 (en) 2003-03-25 2010-03-24 Kiel Lab Inc GABAPENTINIC PHENOLIC ACID SALTS IN SOLID DOSAGE FORMS AND METHODS OF USE
WO2004093780A2 (en) * 2003-04-21 2004-11-04 Matrix Laboratories Ltd Process for the preparation of gabapentin form-ii
US20050187295A1 (en) * 2004-02-19 2005-08-25 Surendra Kalyan Processes for the preparation of gabapentin
GB0416228D0 (en) 2004-07-20 2004-08-25 Sandoz Ind Products S A Process for the preparation of gabapentin
EP2038249B1 (en) * 2006-06-30 2013-09-11 ZaCh System S.p.A. Process for preparing gabapentin
CN101585778B (zh) * 2008-05-19 2014-08-13 上海臣邦医药科技有限公司 一种普瑞巴林制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2264354A (en) * 1937-12-22 1941-12-02 Ig Farbenindustrie Ag Addition products of dienes and unsaturated esters, ketones, or nitriles
US2467927A (en) * 1947-05-29 1949-04-19 Goodrich Co B F Preparation of monomeric alkyl alpha-cyano-acrylates
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2611690A1 (de) * 1976-03-19 1977-09-22 Goedecke Ag Cyclische sulfonyloxyimide
YU162789A (en) * 1988-09-01 1990-12-31 Lonza Ag 2-aza-4-(alcoxycarbonyl) spiro/4,5/decan-3-ones
AU633612B2 (en) * 1989-08-25 1993-02-04 Warner-Lambert Company Improved process for cyclic amino acid anticonvulsant compounds

Also Published As

Publication number Publication date
US5095148A (en) 1992-03-10
DE59006037D1 (de) 1994-07-14
FI905584A0 (fi) 1990-11-12
PT95894B (pt) 1998-01-30
NO177531C (no) 1995-10-04
IL96360A0 (en) 1991-08-16
ES2057334T3 (es) 1994-10-16
US5130455A (en) 1992-07-14
JPH03176459A (ja) 1991-07-31
NO177531B (no) 1995-06-26
DK0432504T3 (da) 1994-07-04
NO904953D0 (no) 1990-11-15
CA2030107A1 (en) 1991-05-17
EP0432504B1 (de) 1994-06-08
ATE106861T1 (de) 1994-06-15
FI905584A7 (fi) 1991-05-17
RU2029761C1 (ru) 1995-02-27
EP0432504A1 (de) 1991-06-19
NO904953L (no) 1991-05-21
YU215290A (sh) 1993-05-28
FI905584L (fi) 1991-05-17

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910404

FG3A Patent granted, date of granting

Effective date: 19971008

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19990430