PT95894A - Processo para a producao de acido 1-(aminometil)-ciclo-hexano-acetico e dos seus intermediarios - Google Patents

Processo para a producao de acido 1-(aminometil)-ciclo-hexano-acetico e dos seus intermediarios

Info

Publication number
PT95894A
PT95894A PT95894A PT9589490A PT95894A PT 95894 A PT95894 A PT 95894A PT 95894 A PT95894 A PT 95894A PT 9589490 A PT9589490 A PT 9589490A PT 95894 A PT95894 A PT 95894A
Authority
PT
Portugal
Prior art keywords
cyanocyclohexyl
aminomethyl
intermediaries
cyclohexane
production
Prior art date
Application number
PT95894A
Other languages
English (en)
Other versions
PT95894B (pt
Inventor
Hans Peter Mettler
Felix Previdoli
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of PT95894A publication Critical patent/PT95894A/pt
Publication of PT95894B publication Critical patent/PT95894B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PT95894A 1989-11-16 1990-11-15 Processo para a producao de acido 1-(aminometil)-ciclo-hexano-acetico e dos seus intermediarios PT95894B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH412889 1989-11-16

Publications (2)

Publication Number Publication Date
PT95894A true PT95894A (pt) 1991-09-13
PT95894B PT95894B (pt) 1998-01-30

Family

ID=4270351

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95894A PT95894B (pt) 1989-11-16 1990-11-15 Processo para a producao de acido 1-(aminometil)-ciclo-hexano-acetico e dos seus intermediarios

Country Status (14)

Country Link
US (2) US5095148A (pt)
EP (1) EP0432504B1 (pt)
JP (1) JPH03176459A (pt)
AT (1) ATE106861T1 (pt)
CA (1) CA2030107A1 (pt)
DE (1) DE59006037D1 (pt)
DK (1) DK0432504T3 (pt)
ES (1) ES2057334T3 (pt)
FI (1) FI905584A7 (pt)
IL (1) IL96360A0 (pt)
NO (1) NO177531C (pt)
PT (1) PT95894B (pt)
RU (1) RU2029761C1 (pt)
YU (1) YU215290A (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ293759B6 (cs) * 1996-03-14 2004-07-14 Warner-Lambert Company Substituovaná cyklická aminokyselina, její použití a farmaceutický prostředek na její bázi
US6372792B1 (en) 1996-04-26 2002-04-16 Guy Chouinard Method for treating anxiety, anxiety disorders and insomnia
US6255526B1 (en) 1996-12-24 2001-07-03 Teva Pharmaceutical Industries Ltd. Preparation of gabapentin
WO1999018063A2 (en) 1997-10-07 1999-04-15 Warner-Lambert Company Process for preparing a cyclic amino acid anticonvulsant compound
HU225502B1 (en) 1998-12-29 2007-01-29 Richter Gedeon Vegyeszet Process for producing 1-(amino-metyl)-cyclohexene-acetic-acid and intermediates
AU2001266992B8 (en) * 2000-06-16 2005-12-01 Teva Pharmaceutical Industries Ltd. Stable gabapentin having pH within a controlled range
IT1319674B1 (it) * 2000-12-01 2003-10-23 Erregierre Spa Processo per la preparazione dell'acido1-(aminometil)cicloesanacetico.
EP1494996A1 (en) * 2002-04-16 2005-01-12 Taro Pharmaceutical Industries Limited Process for preparing gabapentin
ITMI20022071A1 (it) * 2002-10-01 2004-04-02 Erregierre Spa Processo di sintesi dell'acido 1-(aminometil)cicloesanacetico cloridato.
ATE418535T1 (de) 2002-11-18 2009-01-15 Nicholas Piramal India Ltd Verbessertes verfahren zur herstellung von gabapentin
WO2004093866A1 (en) * 2003-03-25 2004-11-04 Kiel Laboratories, Inc. Process for preparing phenolic acid salts of gabapentin
WO2004093827A2 (en) 2003-03-25 2004-11-04 Kiel Laboratories, Inc. Phenolic acid salts of gabapentin in solid dosage forms and methods of use
EP1628656B1 (en) * 2003-03-25 2008-10-15 Kiel Laboratories, Inc. Gabapentin tannate in liquid and/or semi-solid dosage forms
EP1615875A2 (en) * 2003-04-21 2006-01-18 Matrix Laboratories Limited Process for the preparation of gabapentin form-ii
US20050187295A1 (en) * 2004-02-19 2005-08-25 Surendra Kalyan Processes for the preparation of gabapentin
GB0416228D0 (en) 2004-07-20 2004-08-25 Sandoz Ind Products S A Process for the preparation of gabapentin
US8143443B2 (en) * 2006-06-30 2012-03-27 Zach System S.P.A. Process for preparing gabapentin
CN101585778B (zh) * 2008-05-19 2014-08-13 上海臣邦医药科技有限公司 一种普瑞巴林制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2264354A (en) * 1937-12-22 1941-12-02 Ig Farbenindustrie Ag Addition products of dienes and unsaturated esters, ketones, or nitriles
US2467927A (en) * 1947-05-29 1949-04-19 Goodrich Co B F Preparation of monomeric alkyl alpha-cyano-acrylates
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2611690A1 (de) * 1976-03-19 1977-09-22 Goedecke Ag Cyclische sulfonyloxyimide
YU162789A (en) * 1988-09-01 1990-12-31 Lonza Ag 2-aza-4-(alcoxycarbonyl) spiro/4,5/decan-3-ones
MY106864A (en) * 1989-08-25 1995-08-30 Warner Lambert Co Improved process for cyclic amino acid anticonvulsant compounds.

Also Published As

Publication number Publication date
US5130455A (en) 1992-07-14
IL96360A0 (en) 1991-08-16
FI905584L (fi) 1991-05-17
ATE106861T1 (de) 1994-06-15
DK0432504T3 (da) 1994-07-04
NO904953D0 (no) 1990-11-15
DE59006037D1 (de) 1994-07-14
NO177531C (no) 1995-10-04
PT95894B (pt) 1998-01-30
YU215290A (sh) 1993-05-28
RU2029761C1 (ru) 1995-02-27
NO177531B (no) 1995-06-26
FI905584A7 (fi) 1991-05-17
CA2030107A1 (en) 1991-05-17
FI905584A0 (fi) 1990-11-12
EP0432504B1 (de) 1994-06-08
ES2057334T3 (es) 1994-10-16
JPH03176459A (ja) 1991-07-31
NO904953L (no) 1991-05-21
EP0432504A1 (de) 1991-06-19
US5095148A (en) 1992-03-10

Similar Documents

Publication Publication Date Title
FI905584A0 (fi) Foerfarande foer framstaellning av 1-(aminometyl)cyklohexanaettikssyra.
BR9704357A (pt) Processo para produção de acido malônico e de ésteres de acido malônico
IT1183674B (it) Procedimento di fermentazione per produrre acido ialuronico
BR8706104A (pt) Processo para produzir um derivado de azol,um derivado de oxirano,um derivado de ciclopentanona,um derivado de ester de um acido
AU4469779A (en) Acid hydrolysis of cellulose to yield glucose
BR8405314A (pt) Processo para producao de etanol por fermentacao
IT7949662A0 (it) Procedimento per la produzione di acido tereftalico da metiltereftala to come prodotto intermedio
IE790175L (en) Cyano esters; optically active acids
ES2040853T3 (es) Preparacion de acidos oxoftalazinilaceticos con cadenas laterales de benzotiazol u otros heterociclos.
BR8103872A (pt) Processo de preparacao de cultura biologicamente pura de uma variante do microorganismo clostridum thermoaceticum cultura resultante ,e processo para a conversao de carboidraatos de acido acetico
BG49615A3 (bg) Метод за получаване на производни на 3-заместени тиометилцефало- спорини или техни етилови, или дифенилетилови естери, или техни соли
BE889728A (fr) Procede de production de l'enzyme cholesterase et d'hydrolyse des esters de cholesterol d'acides gras en utilisant l'enzyme elle-meme
IT1128571B (it) Processo per preparare anidrici di acido carbossilico
SE8203152L (sv) Forfarande for syntetisering av kolsyraestrar herrorande fran omettade alkoholer och flerverda alkoholer
BR9100532A (pt) Processo para a preparacao de um ester de acido(4-amino-3,5-dicloro-6-fluoro-2-piridimilox)acetico e um alcool alifatico
ES8604521A1 (es) Procedimiento para la obtencion de acidos quinolona- o bien naftiridona-carboxilicos
AU3999493A (en) Process for preparing tetronic acid alkyl esters
ATE38980T1 (de) Verfahren zur herstellung von l-carnitin.
DE3263545D1 (en) Process for the preparation of 4-alkoxy-acetoacetic-acid esters
ES8707174A1 (es) Un procedimiento para preparar esteres de acido trans-beta-benzoilacrilico
BR8206330A (pt) Processo para a producao de acido aminometilfosfonico
DK0492494T3 (da) Fremgangsmåde til fremstilling af procain
IT1136579B (it) Processo per la produzione di acido l-aspartico usando microorganismi immobilizzati
JPS5785339A (en) Production of fluoromalonic ester
SU1363772A1 (ru) Способ получения изопропил-n-фенилкарбамата

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910404

FG3A Patent granted, date of granting

Effective date: 19971008

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19990430