DK0434385T3 - Anvendelse af makrocycliske, nitroholdige forbindelser til behandling af retrovirale infektioner - Google Patents
Anvendelse af makrocycliske, nitroholdige forbindelser til behandling af retrovirale infektionerInfo
- Publication number
- DK0434385T3 DK0434385T3 DK90313899.8T DK90313899T DK0434385T3 DK 0434385 T3 DK0434385 T3 DK 0434385T3 DK 90313899 T DK90313899 T DK 90313899T DK 0434385 T3 DK0434385 T3 DK 0434385T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- macrocyclic
- nitro
- retroviral infections
- containing compounds
- Prior art date
Links
- 206010038997 Retroviral infections Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 150000001923 cyclic compounds Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/454,418 US5021409A (en) | 1989-12-21 | 1989-12-21 | Antiviral cyclic polyamines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0434385T3 true DK0434385T3 (da) | 1995-12-18 |
Family
ID=23804523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90313899.8T DK0434385T3 (da) | 1989-12-21 | 1990-12-19 | Anvendelse af makrocycliske, nitroholdige forbindelser til behandling af retrovirale infektioner |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5021409A (da) |
| EP (1) | EP0434385B1 (da) |
| JP (1) | JP3133345B2 (da) |
| KR (1) | KR0180019B1 (da) |
| AT (1) | ATE130514T1 (da) |
| AU (1) | AU639514B2 (da) |
| CA (1) | CA2032261C (da) |
| DE (1) | DE69023748T2 (da) |
| DK (1) | DK0434385T3 (da) |
| ES (1) | ES2079453T3 (da) |
| GR (1) | GR3018206T3 (da) |
| HU (2) | HUT67031A (da) |
| IE (1) | IE71640B1 (da) |
| IL (1) | IL96666A (da) |
| NZ (1) | NZ236463A (da) |
| PT (1) | PT96289B (da) |
| ZA (1) | ZA9010184B (da) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9105489D0 (en) * | 1991-03-15 | 1991-05-01 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9126677D0 (en) * | 1991-12-16 | 1992-02-12 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9400411D0 (en) * | 1994-01-11 | 1994-03-09 | Johnson Matthey Plc | Improvements in chemical compounds |
| KR100447303B1 (ko) * | 1994-01-11 | 2005-08-23 | 아노메드 인코포레이티드 | 고리형폴리아민 |
| US5663161A (en) * | 1995-02-17 | 1997-09-02 | The Research Foundation Of State University Of New York | Anti-viral triaza compounds |
| US5612478A (en) * | 1995-03-30 | 1997-03-18 | Johnson Matthey Plc | Process for preparing 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane |
| US5606053A (en) * | 1995-05-02 | 1997-02-25 | Johnson Matthey Plc | Process for preparing 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane |
| GB9511357D0 (en) * | 1995-06-06 | 1995-08-02 | Johnson Matthey Plc | Improved antiviral compounds |
| US6506770B1 (en) | 1996-06-06 | 2003-01-14 | Anormed, Inc. | Antiviral compounds |
| EP0847452B1 (en) * | 1995-06-07 | 2009-04-01 | Progenics Pharmaceuticals, Inc. | Monoclonal antibody for inhibiting hiv-1 envelope glycoprotein mediated membrane fusion |
| EP0955044B1 (en) * | 1995-06-26 | 2005-11-16 | Chelator LLC | Method of inhibiting bacterial or fungal growth using a complexing agent |
| US5608061A (en) * | 1995-08-02 | 1997-03-04 | Johnson Matthey Plc | Process for preparing 1,4,8,11-tetraazacyclotetradecane |
| US7118859B2 (en) | 1996-01-17 | 2006-10-10 | Progenics Pharmaceuticals, Inc. | Methods for inhibiting HIV-1 infection |
| US7858298B1 (en) | 1996-04-01 | 2010-12-28 | Progenics Pharmaceuticals Inc. | Methods of inhibiting human immunodeficiency virus type 1 (HIV-1) infection through the administration of CCR5 chemokine receptor antagonists |
| US6344545B1 (en) * | 1996-06-14 | 2002-02-05 | Progenics Pharmaceuticals, Inc. | Method for preventing HIV-1 infection of CD4+ cells |
| US20040086528A1 (en) * | 1996-06-14 | 2004-05-06 | Progenics Pharmaceuticals, Inc. | Uses of a chemokine receptor for inhibiting HIV-1 infection |
| WO2000006086A2 (en) * | 1998-07-31 | 2000-02-10 | The Trustees Of Columbia University In The City Of New York | Use of inhibitors of the activation of cxcr4 receptor by sdf-1 in treating rheumatoid arthritis |
| US20040228869A1 (en) * | 1998-12-16 | 2004-11-18 | Progenics Pharmaceuticals, Inc. | Synergistic inhibition of HIV-1 fusion and attachment, compositions and antibodies thereto |
| US20080015348A1 (en) * | 1998-12-16 | 2008-01-17 | Progenics Pharmaceuticals, Inc. | Nucleic acids encoding polypeptides of anti-CCR5 antibodies |
| US6365583B1 (en) * | 1999-02-02 | 2002-04-02 | Anormed, Inc. | Methods to enhance white blood cell count |
| BR0010655A (pt) * | 1999-03-24 | 2002-02-13 | Anormed Inc | Compostos heterocìclicos para ligação ao receptor de quimiocina |
| US6750348B1 (en) | 1999-03-24 | 2004-06-15 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds |
| AU4678300A (en) * | 1999-04-30 | 2000-11-17 | Slil Biomedical Corporation | Novel polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases |
| US6649587B1 (en) | 1999-04-30 | 2003-11-18 | Slil Biomedical Corporation | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases |
| US6482943B1 (en) * | 1999-04-30 | 2002-11-19 | Slil Biomedical Corporation | Quinones as disease therapies |
| JP4743673B2 (ja) * | 1999-04-30 | 2011-08-10 | プロゲン ファーマシューティカルズ, インコーポレイテッド | ポリアミンおよび治療におけるそれらの使用 |
| DE60042030D1 (de) * | 1999-12-17 | 2009-05-28 | Genzyme Corp | Chemokinrezeptor-bindende heterocyclische verbindungen |
| US8271316B2 (en) * | 1999-12-17 | 2012-09-18 | Buzzmetrics Ltd | Consumer to business data capturing system |
| US20030072715A1 (en) * | 2000-08-02 | 2003-04-17 | Benjamin Frydman | Cyclic polyamine compounds for cancer therapy |
| PT1317451E (pt) * | 2000-09-15 | 2006-12-29 | Anormed Inc | Compostos heterocíclicos que se ligam a receptores de quimioquinas |
| US7138119B2 (en) * | 2000-09-15 | 2006-11-21 | Progenics Pharmaceuticals, Inc. | Compositions and methods for inhibition of HIV-1 infection |
| CA2419224A1 (en) * | 2000-09-15 | 2002-03-21 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds |
| AU2002211393B2 (en) | 2000-09-29 | 2007-06-28 | Anormed Inc. | Process for preparation of n-1 protected n ring nitrogen containing cyclic polyamines and products thereof |
| AU2001297817A1 (en) * | 2000-11-08 | 2002-11-25 | Eli Lilly And Company | Antiviral therapies using polyamine or polyamine analog-amino acid conjugates |
| US7060273B2 (en) * | 2001-04-06 | 2006-06-13 | Progenics Pharmaceuticals, Inc. | Methods for inhibiting HIV-1 infection |
| ES2380009T3 (es) * | 2001-07-31 | 2012-05-07 | Genzyme Global S.A.R.L. | Métodos para movilizar las células madre/progenitoras |
| US7169750B2 (en) * | 2001-07-31 | 2007-01-30 | Anormed, Inc. | Methods to mobilize progenitor/stem cells |
| MXPA04005509A (es) | 2001-12-07 | 2004-12-06 | Slil Biomedical Corp | Poliaminas sustituidas con cicloalquilo para terapia de cancer y metodos de sintesis de las mismas. |
| US7354932B2 (en) | 2001-12-21 | 2008-04-08 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds with enhanced efficacy |
| CA2467718C (en) | 2001-12-21 | 2011-04-26 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds with enhanced efficacy |
| US7122185B2 (en) * | 2002-02-22 | 2006-10-17 | Progenics Pharmaceuticals, Inc. | Anti-CCR5 antibody |
| EP1613613B1 (en) * | 2003-04-11 | 2021-06-02 | Genzyme Corporation | Cxcr4 chemokine receptor binding compounds |
| AU2004232361A1 (en) | 2003-04-22 | 2004-11-04 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds with enhanced efficacy |
| US7501518B2 (en) * | 2003-04-22 | 2009-03-10 | Genzyme Corporation | Methods of making 2,6-diaryl piperidine derivatives |
| US7498346B2 (en) * | 2003-12-11 | 2009-03-03 | Genzyme Corporation | Chemokine receptor binding compounds |
| EP1708703A4 (en) * | 2003-12-11 | 2008-04-09 | Anormed Inc | CHEMOKIN RECEPTOR BINDING COMPOUNDS |
| JP2008509928A (ja) * | 2004-08-13 | 2008-04-03 | アノーメド インコーポレイテッド | 前駆/幹細胞を動員するためのケモカインの組み合わせ |
| EP1942890A4 (en) * | 2005-06-15 | 2009-08-26 | Genzyme Corp | CHEMOKINE RECEPTOR BINDING COMPOUNDS |
| EP1924265A4 (en) * | 2005-08-16 | 2010-06-02 | Genzyme Corp | COMPOUNDS BINDING TO CHEMOKINE RECEPTORS |
| CA2619828A1 (en) | 2005-08-19 | 2007-02-22 | Genzyme Corporation | Methods to enhance chemotherapy |
| MX2008010895A (es) * | 2006-02-24 | 2008-09-03 | Genzyme Corp | Metodos para aumentar el flujo sanguineo y/o promover la regeneracion de tejidos. |
| AU2007281090A1 (en) * | 2006-08-02 | 2008-02-07 | Genzyme Corporation | Combination therapy |
| JP2010507567A (ja) * | 2006-08-07 | 2010-03-11 | ジェンザイム・コーポレーション | 併用療法 |
| RU2638802C2 (ru) | 2011-05-16 | 2017-12-15 | Джензим Корпорейшн | Применение антагонистов cxcr4 |
| CA3026154A1 (en) | 2015-06-03 | 2016-12-08 | The University Of Queensland | Mobilizing agents and uses therefor |
| WO2017106332A1 (en) | 2015-12-14 | 2017-06-22 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| CN109069426B (zh) | 2015-12-14 | 2021-10-29 | X4 制药有限公司 | 治疗癌症的方法 |
| WO2017106630A1 (en) | 2015-12-18 | 2017-06-22 | The General Hospital Corporation | Polyacetal polymers, conjugates, particles and uses thereof |
| PL3393468T3 (pl) | 2015-12-22 | 2023-01-23 | X4 Pharmaceuticals, Inc. | Metody leczenia niedoboru odporności |
| US11337969B2 (en) | 2016-04-08 | 2022-05-24 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| WO2017223243A1 (en) | 2016-06-21 | 2017-12-28 | X4 Pharmaceuticals, Inc. | Cxcr4 inhibitors and uses thereof |
| ES2870920T3 (es) | 2016-06-21 | 2021-10-28 | X4 Pharmaceuticals Inc | Inhibidores de CXCR4 y usos de los mismos |
| CN109640988A (zh) | 2016-06-21 | 2019-04-16 | X4 制药有限公司 | Cxcr4抑制剂及其用途 |
| WO2018106738A1 (en) | 2016-12-05 | 2018-06-14 | Massachusetts Institute Of Technology | Brush-arm star polymers, conjugates and particles, and uses thereof |
| EP3704232A1 (en) | 2017-10-31 | 2020-09-09 | Magenta Therapeutics, Inc. | Compositions and methods for the expansion of hematopoietic stem and progenitor cells |
| WO2019089833A1 (en) | 2017-10-31 | 2019-05-09 | Magenta Therapeutics Inc. | Compositions and methods for hematopoietic stem and progenitor cell transplant therapy |
| CN111712262A (zh) | 2017-12-06 | 2020-09-25 | 美真达治疗公司 | 用于动员造血干细胞和祖细胞的给药方案 |
| US11260079B2 (en) | 2017-12-06 | 2022-03-01 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem and progenitor cells |
| EP3735412B1 (en) | 2018-01-03 | 2024-02-21 | EdiGene Biotechnology, Inc. | Compositions and methods for the expansion of hematopoietic stem and progenitor cells and treatment of inherited metabolic disorders |
| US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
| WO2020112195A1 (en) | 2018-11-30 | 2020-06-04 | Yale University | Compositions, technologies and methods of using plerixafor to enhance gene editing |
| US20220401481A1 (en) | 2019-11-01 | 2022-12-22 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem and progenitor cells |
| CA3171250A1 (en) | 2020-03-10 | 2021-09-16 | E. Lynne KELLEY | Methods for treating neutropenia |
| CA3176979A1 (en) | 2020-04-27 | 2021-11-04 | Anthony Boitano | Methods and compositions for transducing hematopoietic stem and progenitor cells in vivo |
| WO2022197776A1 (en) | 2021-03-16 | 2022-09-22 | Magenta Therapeutics, Inc. | Dosing regimens for hematopoietic stem cell mobilization for stem cell transplants in multiple myeloma patients |
| WO2025224720A1 (en) | 2024-04-24 | 2025-10-30 | Biolinerx Ltd. | Methods of selecting treatment regimen against solid tumors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4156683A (en) * | 1973-03-26 | 1979-05-29 | Schering Corporation | Complexes of macrocyclic compounds |
| FR2614020B1 (fr) * | 1987-04-14 | 1989-07-28 | Guerbet Sa | Nouveaux ligands cycliques azotes, complexes metalliques formes par ces ligands, compositions de diagnostic contenant ces complexes et procede de preparation des ligands. |
| DE3713842A1 (de) * | 1987-04-22 | 1988-11-17 | Schering Ag | Substituierte cyclische komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel |
| DE4035760A1 (de) * | 1990-11-08 | 1992-05-14 | Schering Ag | Mono-n-substituierte 1,4,7,10-tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
-
1989
- 1989-12-21 US US07/454,418 patent/US5021409A/en not_active Expired - Lifetime
-
1990
- 1990-12-14 AU AU68090/90A patent/AU639514B2/en not_active Ceased
- 1990-12-14 NZ NZ236463A patent/NZ236463A/en unknown
- 1990-12-14 IL IL9666690A patent/IL96666A/en not_active IP Right Cessation
- 1990-12-14 CA CA002032261A patent/CA2032261C/en not_active Expired - Lifetime
- 1990-12-18 ZA ZA9010184A patent/ZA9010184B/xx unknown
- 1990-12-19 ES ES90313899T patent/ES2079453T3/es not_active Expired - Lifetime
- 1990-12-19 DK DK90313899.8T patent/DK0434385T3/da active
- 1990-12-19 EP EP90313899A patent/EP0434385B1/en not_active Expired - Lifetime
- 1990-12-19 KR KR1019900021096A patent/KR0180019B1/ko not_active Expired - Fee Related
- 1990-12-19 DE DE69023748T patent/DE69023748T2/de not_active Expired - Lifetime
- 1990-12-19 AT AT90313899T patent/ATE130514T1/de not_active IP Right Cessation
- 1990-12-20 IE IE461990A patent/IE71640B1/en not_active IP Right Cessation
- 1990-12-20 PT PT96289A patent/PT96289B/pt not_active IP Right Cessation
- 1990-12-20 HU HU908367A patent/HUT67031A/hu unknown
- 1990-12-21 JP JP02404955A patent/JP3133345B2/ja not_active Expired - Lifetime
-
1994
- 1994-07-11 HU HU94P/P00011P patent/HU210534A9/hu unknown
-
1995
- 1995-11-23 GR GR950403260T patent/GR3018206T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU639514B2 (en) | 1993-07-29 |
| JPH06219945A (ja) | 1994-08-09 |
| IE71640B1 (en) | 1997-02-26 |
| IE904619A1 (en) | 1991-07-17 |
| GR3018206T3 (en) | 1996-02-29 |
| JP3133345B2 (ja) | 2001-02-05 |
| PT96289A (pt) | 1991-10-15 |
| EP0434385A2 (en) | 1991-06-26 |
| IL96666A (en) | 1996-01-31 |
| ES2079453T3 (es) | 1996-01-16 |
| HU908367D0 (en) | 1991-07-29 |
| DE69023748D1 (de) | 1996-01-04 |
| US5021409A (en) | 1991-06-04 |
| HUT67031A (en) | 1995-01-30 |
| DE69023748T2 (de) | 1996-05-02 |
| ZA9010184B (en) | 1991-11-27 |
| PT96289B (pt) | 1998-06-30 |
| NZ236463A (en) | 1992-04-28 |
| HU210534A9 (en) | 1995-04-28 |
| KR0180019B1 (ko) | 1999-03-20 |
| KR910011267A (ko) | 1991-08-07 |
| AU6809090A (en) | 1991-06-27 |
| EP0434385B1 (en) | 1995-11-22 |
| EP0434385A3 (en) | 1992-03-04 |
| ATE130514T1 (de) | 1995-12-15 |
| IL96666A0 (en) | 1991-09-16 |
| CA2032261C (en) | 2002-04-23 |
| CA2032261A1 (en) | 1991-06-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0434385T3 (da) | Anvendelse af makrocycliske, nitroholdige forbindelser til behandling af retrovirale infektioner | |
| NO306720B1 (no) | Sykliske ureaer og analoger som er anvendbare som retrovirale proteaseinhibitorer, farmasöytiske preparater omfattende disse og anvendelse av forbindelsene for fremstilling av farmasöytiske preparater | |
| DK0521787T3 (da) | Vanadiumkomplekser, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem | |
| FI921030A0 (fi) | Cykliska ureaderivat, dessa foereningar innehaollande laekemedel och foerfarande foer deras framstaellning. | |
| NO174296C (no) | Analogifremgangsmåte til fremstilling av terapeutisk aktive 1-indolylalkyl-4-(substituert-pyridinyl)piperaziner | |
| DK202388A (da) | Azabicycliske forbindelser og fremgangsmaade til fremstilling deraf | |
| ATE79376T1 (de) | Dithioacetal-verbindungen, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
| DK0452204T3 (da) | Hidtil ukendte 3-aminochromanderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem | |
| DK624989D0 (da) | Hidtil ukendte forbindelser | |
| SE8303913D0 (sv) | Heterocykliska foreningar | |
| DE69007356D1 (de) | Zyklisches Tetrapeptid und Verfahren zu dessen Herstellung. | |
| EP0339834A3 (en) | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | |
| ATE101119T1 (de) | Butensaeure-amide, deren salze, diese enthaltende pharmazeutische zusammensetzungen und verfahren zu deren herstellung. | |
| SE8802162L (sv) | Nya aminoacylater av glycerolacetal | |
| NO903084L (no) | Farmasoeytisk anvendbare thiazolderivater og fremgangsmaatefor deresfremstilling. | |
| TH18165A (th) | สารยับยั้งการเกิดคีโมแทกซิของอีโอซีโนฟีล | |
| TH3421A (th) | สารประกอบชนิดต่อต้านการอักเสบ/บรรเทาอาการแพ้ |