DK202388D0 - Hidtil ukendte forbindelser - Google Patents

Hidtil ukendte forbindelser

Info

Publication number: DK202388D0
Authority: DK; Denmark
Prior art keywords: group; chem; alkyl; nitrogen; methyl
Prior art date: 1987-04-15

Application number

DK202388A

Other languages

English (en)

Other versions

DK202388A (da

Inventor

Michael Stewart Hadley

Paul Adran Wyman

Barry Sidney Orlek

Original Assignee

Beecham Group Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-04-15

Filing date

1988-04-13

Publication date

1988-04-13

1987-04-15 Priority claimed from GB878709025A external-priority patent/GB8709025D0/en

1987-12-22 Priority claimed from GB878729809A external-priority patent/GB8729809D0/en

1988-02-24 Priority claimed from GB888804224A external-priority patent/GB8804224D0/en

1988-04-13 Application filed by Beecham Group Plc filed Critical Beecham Group Plc

1988-04-13 Publication of DK202388D0 publication Critical patent/DK202388D0/da

1988-10-16 Publication of DK202388A publication Critical patent/DK202388A/da

Links

IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 3
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
239000005864 Sulphur Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
229910052757 nitrogen Inorganic materials 0.000 abstract 2
239000001301 oxygen Substances 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000006656 (C2-C4) alkenyl group Chemical group 0.000 abstract 1
125000006650 (C2-C4) alkynyl group Chemical group 0.000 abstract 1
OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 1
125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Recording Measured Values (AREA)
Luminescent Compositions (AREA)
Hydrogenated Pyridines (AREA)
Pyrrole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Peptides Or Proteins (AREA)
Steroid Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK202388A 1987-04-15 1988-04-13 Azabicycliske forbindelser og fremgangsmaade til fremstilling deraf DK202388A (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB878709025A GB8709025D0 (en)	1987-04-15	1987-04-15	Compounds
GB878729809A GB8729809D0 (en)	1987-12-22	1987-12-22	Novel compounds
GB888804224A GB8804224D0 (en)	1988-02-24	1988-02-24	Novel compounds

Publications (2)

Publication Number	Publication Date
DK202388D0 true DK202388D0 (da)	1988-04-13
DK202388A DK202388A (da)	1988-10-16

Family

ID=27263387

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK202388A DK202388A (da)	1987-04-15	1988-04-13	Azabicycliske forbindelser og fremgangsmaade til fremstilling deraf

Country Status (8)

Country	Link
US (2)	US4971975A (da)
EP (1)	EP0287356B1 (da)
JP (1)	JP2651695B2 (da)
AT (1)	ATE133415T1 (da)
AU (1)	AU614513B2 (da)
DE (1)	DE3854932T2 (da)
DK (1)	DK202388A (da)
NZ (1)	NZ224237A (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ219646A (en) *	1986-03-27	1990-10-26	Merck Sharp & Dohme	Oxadiazole derivatives of azacyclics for treating cns disorders
EP0307141B1 (en) *	1987-09-10	1993-01-13	MERCK SHARP & DOHME LTD.	Oxazoles and thiazoles for the treatment of senile dementia
EP0322182A3 (en) *	1987-12-22	1992-01-02	Beecham Group Plc	Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
NZ227684A (en) *	1988-01-30	1991-07-26	Merck Sharp & Dohme	Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions
PT90266B (pt) *	1988-04-15	1994-07-29	Beecham Group Plc	Processo para a preparacao de compostos azabiciclicos
GB8808926D0 (en) *	1988-04-15	1988-05-18	Beecham Group Plc	Novel compounds
EP0363085A3 (en)	1988-10-03	1991-03-27	Beecham Group Plc	Novel compounds
CA2000041A1 (en) *	1988-10-13	1990-04-13	Barry S. Orlek	Compounds
SG48315A1 (en) *	1989-04-13	1998-04-17	Beecham Group Plc	Novel compounds
EP0402056A3 (en) *	1989-06-06	1991-09-04	Beecham Group p.l.c.	Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
GB8917957D0 (en) *	1989-08-05	1989-09-20	Beecham Group Plc	Novel compounds
US5157160A (en) *	1989-08-16	1992-10-20	Beecham Group P.L.C.	Certain 5-substituted-1-azabicyclo[3.1.1]heptanes and their pharmaceutical use
ATE153024T1 (de) *	1989-08-16	1997-05-15	Beecham Group Plc	Azabicyclische verbindungen
EP0427390B1 (en) *	1989-10-07	1996-03-27	Beecham Group Plc	Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them
YU84791A (sh) *	1990-05-19	1994-06-10	Boehringer Ingelheim Kg.	Biciklicni 1-aza-cikloalkalni
WO1992003435A1 (en) *	1990-08-24	1992-03-05	Beecham Group Plc	Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them
GB9019095D0 (en) *	1990-09-01	1990-10-17	Beecham Group Plc	Novel compounds
CA2093823A1 (en) *	1990-10-12	1992-04-13	Steven M. Bromidge	1,2,5,6-tetrahydropyridine oxime derivatives
AU2782792A (en) *	1991-10-15	1993-05-21	Warner-Lambert Company	Azabicyclo oxime and amine cholinergic agents and methods of treatment
SE9201478D0 (sv) *	1992-05-11	1992-05-11	Kabi Pharmacia Ab	Heteroaromatic quinuclidinenes, their use and preparation
US5679693A (en) *	1992-09-30	1997-10-21	Sanofi	1-azoniabicyclo 2.2.1!heptanes, method of preparing them and pharmaceutical compositions in which they are present
WO1994018201A1 (fr) *	1993-02-12	1994-08-18	Sankyo Company, Limited	Derive d'isoxazoleoxy
GB9507203D0 (en) *	1995-04-07	1995-05-31	Smithkline Beecham Plc	Novel compounds
US5733912A (en) *	1997-02-19	1998-03-31	Abbott Laboratories	7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
US6875774B2 (en) *	2002-08-06	2005-04-05	The University Of North Carolina	Aza-bridged bicyclic amine derivatives for use as novel cholinergic receptor ligands
GB0220581D0 (en)	2002-09-04	2002-10-09	Novartis Ag	Organic Compound
PE20060437A1 (es)	2004-06-18	2006-06-08	Novartis Ag	COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR
GB0415746D0 (en)	2004-07-14	2004-08-18	Novartis Ag	Organic compounds
JP2009506069A (ja)	2005-08-26	2009-02-12	ブレインセルス，インコーポレイティド	ムスカリン性受容体調節による神経発生
EP2258359A3 (en)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation with sabcomelin
GB0521508D0 (en)	2005-10-21	2005-11-30	Novartis Ag	Organic compounds
GB0525672D0 (en)	2005-12-16	2006-01-25	Novartis Ag	Organic compounds
GB0525673D0 (en)	2005-12-16	2006-01-25	Novartis Ag	Organic compounds
EP2068872A1 (en)	2006-09-08	2009-06-17	Braincells, Inc.	Combinations containing a 4-acylaminopyridine derivative
BRPI0806972A2 (pt)	2007-02-09	2014-04-08	Astellas Pharma Inc	Composto cíclico contendo ponte azo

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS56156283A (en) *	1980-05-07	1981-12-02	Suntory Ltd	8-substituted pyrrolitidine and its quaternary ammonium salt
JPH0633286B2 (ja) *	1985-01-14	1994-05-02	エーザイ株式会社	セフエム誘導体
US4771051A (en) *	1985-05-17	1988-09-13	A/S Ferrosan	3-substituted-4,5-dihydro-5-oxo imidazoquinazolines, their preparation, and their use in treating benzodiazepin receptor-related ailments
EP0235878A3 (en) *	1986-01-16	1989-06-14	Beecham Group Plc	Novel compounds
GB8607713D0 (en)	1986-03-27	1986-04-30	Merck Sharpe & Dohme Ltd	Oxadiazoles
NZ219646A (en) *	1986-03-27	1990-10-26	Merck Sharp & Dohme	Oxadiazole derivatives of azacyclics for treating cns disorders
GB8630896D0 (en)	1986-12-24	1987-02-04	Merck Sharp & Dohme	Oxadiazoles
GB8615784D0 (en)	1986-06-27	1986-08-06	Beecham Group Plc	Compounds
GB8622380D0 (en)	1986-09-17	1986-10-22	Beecham Group Plc	Compounds
EP0261763B1 (en) *	1986-06-27	1994-02-09	Beecham Group Plc	Novel bridged bicyclic N-heterocycles
GB8615785D0 (en) *	1986-06-27	1986-08-06	Beecham Group Plc	Compounds
GB8801758D0 (en)	1988-01-27	1988-02-24	Merck Sharp & Dohme	Therapeutic agents
GB8817311D0 (en)	1988-07-20	1988-08-24	Merck Sharp & Dohme	Therapeutic agents
GB8812145D0 (en)	1988-05-23	1988-06-29	Merck Sharp & Dohme	Therapeutic agents
GB8721342D0 (en)	1987-09-10	1987-10-14	Merk Sharp & Dohme Ltd	Therapeutic agents
NZ225999A (en) *	1987-09-10	1992-04-28	Merck Sharp & Dohme	Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
EP0307141B1 (en) *	1987-09-10	1993-01-13	MERCK SHARP & DOHME LTD.	Oxazoles and thiazoles for the treatment of senile dementia
GB8721343D0 (en)	1987-09-10	1987-10-14	Merk Sharp & Dohme Ltd	Therapeutic agents
GB8801759D0 (en)	1988-01-27	1988-02-24	Merck Sharp & Dohme	Therapeutic agents

1988
- 1988-04-13 EP EP88303334A patent/EP0287356B1/en not_active Expired - Lifetime
- 1988-04-13 AT AT88303334T patent/ATE133415T1/de not_active IP Right Cessation
- 1988-04-13 DK DK202388A patent/DK202388A/da not_active Application Discontinuation
- 1988-04-13 AU AU14557/88A patent/AU614513B2/en not_active Ceased
- 1988-04-13 NZ NZ224237A patent/NZ224237A/en unknown
- 1988-04-13 DE DE3854932T patent/DE3854932T2/de not_active Expired - Fee Related
- 1988-04-14 JP JP63090466A patent/JP2651695B2/ja not_active Expired - Lifetime
- 1988-04-15 US US07/182,139 patent/US4971975A/en not_active Expired - Fee Related
1990
- 1990-09-21 US US07/573,641 patent/US5132316A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU1455788A (en)	1988-10-27
ATE133415T1 (de)	1996-02-15
AU614513B2 (en)	1991-09-05
US4971975A (en)	1990-11-20
NZ224237A (en)	1991-04-26
JPS63290878A (ja)	1988-11-28
EP0287356A2 (en)	1988-10-19
EP0287356A3 (en)	1989-09-20
EP0287356B1 (en)	1996-01-24
JP2651695B2 (ja)	1997-09-10
DK202388A (da)	1988-10-16
DE3854932T2 (de)	1996-06-13
US5132316A (en)	1992-07-21
DE3854932D1 (de)	1996-03-07

Legal Events

Date	Code	Title	Description
1993-11-22	AHS	Application shelved for other reasons than non-payment

Publication	Publication Date	Title
DE3854932D1 (de)	1996-03-07	Am Brückenkopf substituierte Azabicyclenderivate
DE69207017D1 (de)	1996-02-08	Benzamide
ES2079453T3 (es)	1996-01-16	Mejoras en compuestos quimicos.
ATE156123T1 (de)	1997-08-15	Cyclische harnstoffe und analoga verwendbar als retrovirale proteasehemmer
NO892058L (no)	1989-11-27	Fremgangsmaate for fremstilling av terapeutisk aktive benzamider.
ATE98634T1 (de)	1994-01-15	Acryloylsubstituierte pyrrol-derivate.
DK504889D0 (da)	1989-10-11	Hidtil ukendte forbindelser
IT1219689B (it)	1990-05-24	Perossiacidi azotati monopersolfati
AU5473194A (en)	1994-08-04	Modified oligodeoxyribonucleotides, their preparation and their therapeutic use
DE3885415D1 (de)	1993-12-09	Salze von Amino-(poly)-percarbonsäuren.
EP0414394A3 (en)	1991-05-08	Novel compounds
AU639493B2 (en)	1993-07-29	Azabicyclo compounds
SE8303913L (sv)	1984-01-09	Heterocykliska foreningar
ATE153024T1 (de)	1997-05-15	Azabicyclische verbindungen
FI903511A0 (fi)	1990-07-11	Pyrrolo (2,1-b) tiazolderivat.