DK0441765T3 - Nye enzymsubstrater på basis af fedtsyreanaloger - Google Patents
Nye enzymsubstrater på basis af fedtsyreanalogerInfo
- Publication number
- DK0441765T3 DK0441765T3 DK91870022.0T DK91870022T DK0441765T3 DK 0441765 T3 DK0441765 T3 DK 0441765T3 DK 91870022 T DK91870022 T DK 91870022T DK 0441765 T3 DK0441765 T3 DK 0441765T3
- Authority
- DK
- Denmark
- Prior art keywords
- fatty acid
- enzyme substrates
- acid analogues
- substrates based
- new enzyme
- Prior art date
Links
- 150000004665 fatty acids Chemical class 0.000 title abstract 4
- 235000014113 dietary fatty acids Nutrition 0.000 title abstract 3
- 229930195729 fatty acid Natural products 0.000 title abstract 3
- 239000000194 fatty acid Substances 0.000 title abstract 3
- 102000004190 Enzymes Human genes 0.000 title abstract 2
- 108090000790 Enzymes Proteins 0.000 title abstract 2
- 239000000758 substrate Substances 0.000 title abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/12—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/60—Unsaturated compounds containing ether groups, groups, groups, or groups the non-carboxylic part of the ether being unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/478,298 US5082967A (en) | 1988-06-16 | 1990-02-09 | Novel fatty acid analog enzyme substrates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0441765T3 true DK0441765T3 (da) | 1994-06-13 |
Family
ID=23899339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91870022.0T DK0441765T3 (da) | 1990-02-09 | 1991-02-08 | Nye enzymsubstrater på basis af fedtsyreanaloger |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5082967A (da) |
| EP (1) | EP0441765B1 (da) |
| JP (1) | JPH05271181A (da) |
| AT (1) | ATE105544T1 (da) |
| CA (1) | CA2036027A1 (da) |
| DE (1) | DE69101934T2 (da) |
| DK (1) | DK0441765T3 (da) |
| ES (1) | ES2054480T3 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0445097T3 (da) * | 1990-02-26 | 1996-09-16 | Univ Washington | Fremgangsmåde til N-myristoylering af protein |
| ES2088480T3 (es) * | 1990-10-12 | 1996-08-16 | Univ Washington | Sustratos de enzimas analogos de acidos grasos sustituidos con azido. |
| EP0618927A4 (en) * | 1991-12-10 | 1995-05-24 | Tanox Biosystems Inc | CYTOKINE WITH AN UNPAIRED CYSTEIN REST AND CONJUGATES OF IT. |
| US5236955A (en) * | 1992-04-10 | 1993-08-17 | Washington University | Anti-fungal agent |
| US6602861B1 (en) * | 1992-04-16 | 2003-08-05 | Research Corporation Technologies, Inc. | Acylated phospholipid drugs |
| US5599947A (en) * | 1993-01-14 | 1997-02-04 | G. D. Searle & Co. | Fatty acid analogs and prodrugs |
| US5859052A (en) * | 1993-01-14 | 1999-01-12 | G. D. Searle & Co. | Fatty acid analogs and prodrugs |
| US6410775B1 (en) * | 1995-06-07 | 2002-06-25 | La Jolla Pharmaceutical Company | APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies |
| WO2000037464A2 (en) | 1998-12-18 | 2000-06-29 | Basilea Pharmaceutica Ag | 4-(aminoalkoxy)benzofurans as n-myristoyltransferase inhibitors |
| US11021430B2 (en) | 2016-04-05 | 2021-06-01 | Moresco Corporation | Oxa acid compound |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3654326A (en) * | 1970-07-22 | 1972-04-04 | Hoffmann La Roche | 5 9-dioxodecanoic acids and methods for their preparation |
| DE3135946A1 (de) * | 1981-09-10 | 1983-03-24 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von alkoxyessigsaeuren |
| DE3230677A1 (de) * | 1982-08-18 | 1984-02-23 | Chemische Werke Hüls AG, 4370 Marl | Verfahren zur herstellung von carboxymethylierten alkoholen, etheralkoholen, thioalkoholen oder alkylphenolen |
| US4778877A (en) * | 1986-08-07 | 1988-10-18 | Washington University | Novel inhibitor peptides II |
| US4740588A (en) * | 1986-08-07 | 1988-04-26 | Washington University | Novel substrate peptides |
| US4778878A (en) * | 1986-08-07 | 1988-10-18 | Washington University | Novel inhibitor peptides I |
| TR23339A (tr) * | 1987-06-15 | 1989-12-14 | Henkel Kgaa | Alkoksillendirme icin katalizoer,olarak eter karbonik asitlerinin toprak alkalisi tozlarinin kullanilmasi |
| DE3728600A1 (de) * | 1987-08-27 | 1989-03-09 | Hoechst Ag | Verfahren zur markierung von substanzen mit technetium oder rhenium |
| DE68901781T2 (de) * | 1988-02-03 | 1993-01-07 | Univ Washington | Enzymsubstrate auf der basis neuer fettsaeureanaloge. |
-
1990
- 1990-02-09 US US07/478,298 patent/US5082967A/en not_active Expired - Fee Related
-
1991
- 1991-02-08 DK DK91870022.0T patent/DK0441765T3/da active
- 1991-02-08 JP JP3017567A patent/JPH05271181A/ja active Pending
- 1991-02-08 AT AT9191870022T patent/ATE105544T1/de not_active IP Right Cessation
- 1991-02-08 CA CA002036027A patent/CA2036027A1/en not_active Abandoned
- 1991-02-08 EP EP91870022A patent/EP0441765B1/en not_active Expired - Lifetime
- 1991-02-08 ES ES91870022T patent/ES2054480T3/es not_active Expired - Lifetime
- 1991-02-08 DE DE69101934T patent/DE69101934T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0441765B1 (en) | 1994-05-11 |
| CA2036027A1 (en) | 1991-08-10 |
| EP0441765A1 (en) | 1991-08-14 |
| ATE105544T1 (de) | 1994-05-15 |
| ES2054480T3 (es) | 1994-08-01 |
| DE69101934T2 (de) | 1994-12-08 |
| US5082967A (en) | 1992-01-21 |
| DE69101934D1 (de) | 1994-06-16 |
| JPH05271181A (ja) | 1993-10-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK193488A (da) | Saccharosefedtsyreester | |
| DK0980349T3 (da) | Fremgangsmåde til fremstilling af syntetiske triglycerider på basis af konjugeret linolsyre | |
| AU1441488A (en) | Compositions containing novel solid, nondigestible, fat-like compounds | |
| DK0441765T3 (da) | Nye enzymsubstrater på basis af fedtsyreanaloger | |
| DE69212925D1 (de) | Polymerisationsinhibitoren für Acrylsäure und Ester | |
| IL94720A0 (en) | Soil-less culture component | |
| ATE8797T1 (de) | Schwielenkultur in einer nahrhaften stroemung. | |
| CA1274537C (en) | PENTAERYTHRITOL-TYPE COESTERS | |
| DK0535939T3 (da) | Fremgangsmåde til fremstilling af omega 9-type polyumættet fedtsyre | |
| DK0415902T3 (da) | Oxy- eller thiosubstituerede fedtsyreanaloger til anvendelse ved behandling af retrovirale infektioner | |
| ES474408A1 (es) | Procedimiento para la obtencion de 1,4-dihidropiridinas con agrupaciones ester sulfurosas | |
| ATE61051T1 (de) | Substituierte pyrimidinamide von oelsaeure oder linolsaeure als inhibitoren von acyl-coa cholesterin-acyltransferase. | |
| FI924823A0 (fi) | Nya fasta, daoligt smaeltbara, fettliknande foereningar samt livsmedelskompositioner innehaollande desamma | |
| BR9910677A (pt) | Processo de preparação de ésteres de<244>-fenilalanina substancialmenteenantiomericamente puros e utilização de umaenzima total ou parcialmente purificada de tipoprotease | |
| ES2076369T3 (es) | Procedimiento para la separacion de racematos de esteres de acidos 4-aril-2-oxo-pirrolidina-3-carboxilicos. | |
| ATE180007T1 (de) | Laminierklebstoff-zusammensetzungen für verpackungszwecke | |
| AU527894B2 (en) | Bis-penicillin esters of alkane diols | |
| ITFI930160A1 (it) | Processo ed apparecchiatura per la produzione di elettricita' con turbine a gas alimentate mediante derivati dal sorgo zuccherino o da culture analoghe | |
| DK0567830T3 (da) | Fremgangsmåde til modifikation af lipaser | |
| ATE200688T1 (de) | Verwendung von formzusammensetzungen als entformungsmittel für elastomerteile. |