DK0445097T3 - Fremgangsmåde til N-myristoylering af protein - Google Patents
Fremgangsmåde til N-myristoylering af proteinInfo
- Publication number
- DK0445097T3 DK0445097T3 DK91870031.1T DK91870031T DK0445097T3 DK 0445097 T3 DK0445097 T3 DK 0445097T3 DK 91870031 T DK91870031 T DK 91870031T DK 0445097 T3 DK0445097 T3 DK 0445097T3
- Authority
- DK
- Denmark
- Prior art keywords
- gene
- myristoyltransferase
- replication
- coli
- origin
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 241000588724 Escherichia coli Species 0.000 abstract 2
- 108010016306 Glycylpeptide N-tetradecanoyltransferase Proteins 0.000 abstract 2
- 230000010076 replication Effects 0.000 abstract 2
- 101150023438 NMT gene Proteins 0.000 abstract 1
- 229960000723 ampicillin Drugs 0.000 abstract 1
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 abstract 1
- 230000009977 dual effect Effects 0.000 abstract 1
- 229930027917 kanamycin Natural products 0.000 abstract 1
- 229960000318 kanamycin Drugs 0.000 abstract 1
- SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 abstract 1
- 229930182823 kanamycin A Natural products 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229940105132 myristate Drugs 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 101150079601 recA gene Proteins 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- TUNFSRHWOTWDNC-UHFFFAOYSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48510390A | 1990-02-26 | 1990-02-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0445097T3 true DK0445097T3 (da) | 1996-09-16 |
Family
ID=23926912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91870031.1T DK0445097T3 (da) | 1990-02-26 | 1991-02-25 | Fremgangsmåde til N-myristoylering af protein |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5436138A (da) |
| EP (1) | EP0445097B1 (da) |
| JP (1) | JPH06245775A (da) |
| AT (1) | ATE141644T1 (da) |
| CA (1) | CA2036965A1 (da) |
| DE (1) | DE69121435T2 (da) |
| DK (1) | DK0445097T3 (da) |
| ES (1) | ES2091903T3 (da) |
| GR (1) | GR3021484T3 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807702A (en) * | 1995-02-27 | 1998-09-15 | Abbott Laboratories | Method for expressing phosphorylated recombinant human β-casein in a bacterial system |
| US5710044A (en) * | 1995-02-27 | 1998-01-20 | Abbott Laboratories | Plasmid for expressing phosphorylated recombinant proteins in a bacterial system |
| JPH11500920A (ja) * | 1995-02-27 | 1999-01-26 | アボツト・ラボラトリーズ | 修飾された組換えタンパク質を細菌系において発現させるプラスミド |
| US5942254A (en) * | 1995-02-27 | 1999-08-24 | Abbott Laboratories | Phosphorylated recombinant human β-casein expressed in a bacterial system |
| CA2213857A1 (en) * | 1995-02-27 | 1996-09-06 | Abbott Laboratories | A method for expressing modified recombinant proteins in a bacterial system |
| US5807700A (en) * | 1995-11-27 | 1998-09-15 | Washington University | Method of screening anti-amebic agents with an E. coli mutant having a deleted adhE gene complemented by the E. histolytica EhADH2 gene |
| AU7364098A (en) * | 1997-04-30 | 1998-11-24 | Trustees Of The University Of Pennsylvania, The | Bacterial interaction screening system |
| AU2007352618B2 (en) | 2007-05-02 | 2013-07-18 | Boehringer Ingelheim Animal Health USA Inc. | DNA plasmids having improved expression and stability |
| EP2850095B1 (en) | 2012-05-17 | 2019-10-09 | RA Pharmaceuticals, Inc. | Peptide and peptidomimetic inhibitors |
| EP3585798A4 (en) * | 2017-02-27 | 2020-10-14 | Duke University | IN VIVO PROTEIN N ACYLATION |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5013662A (en) * | 1985-09-20 | 1991-05-07 | Cetus Corporation | Bacterial methionine n-terminal peptidase |
| US4778877A (en) * | 1986-08-07 | 1988-10-18 | Washington University | Novel inhibitor peptides II |
| US4740588A (en) * | 1986-08-07 | 1988-04-26 | Washington University | Novel substrate peptides |
| US4709012A (en) * | 1986-08-07 | 1987-11-24 | Washington University | Novel inhibitor peptides |
| US4778878A (en) * | 1986-08-07 | 1988-10-18 | Washington University | Novel inhibitor peptides I |
| US4942130A (en) * | 1987-01-14 | 1990-07-17 | President & Fellows Of Harvard College | T7 DNA polymerase |
| US5073571A (en) * | 1988-06-16 | 1991-12-17 | Washington University | Method of inhibiting virus |
| US5082967A (en) * | 1988-06-16 | 1992-01-21 | Washington University | Novel fatty acid analog enzyme substrates |
| US5108919A (en) * | 1988-06-24 | 1992-04-28 | Genentech, Inc. | Dna sequences encoding yeast ubiquitin hydrolase |
-
1991
- 1991-02-25 DK DK91870031.1T patent/DK0445097T3/da active
- 1991-02-25 CA CA002036965A patent/CA2036965A1/en not_active Abandoned
- 1991-02-25 AT AT91870031T patent/ATE141644T1/de not_active IP Right Cessation
- 1991-02-25 ES ES91870031T patent/ES2091903T3/es not_active Expired - Lifetime
- 1991-02-25 DE DE69121435T patent/DE69121435T2/de not_active Expired - Fee Related
- 1991-02-25 JP JP3030426A patent/JPH06245775A/ja active Pending
- 1991-02-25 EP EP91870031A patent/EP0445097B1/en not_active Expired - Lifetime
-
1993
- 1993-07-12 US US08/090,383 patent/US5436138A/en not_active Expired - Fee Related
-
1994
- 1994-07-13 US US08/274,606 patent/US5504008A/en not_active Expired - Fee Related
-
1996
- 1996-10-25 GR GR960402843T patent/GR3021484T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69121435D1 (de) | 1996-09-26 |
| ATE141644T1 (de) | 1996-09-15 |
| EP0445097A3 (en) | 1992-01-08 |
| US5504008A (en) | 1996-04-02 |
| CA2036965A1 (en) | 1991-08-27 |
| US5436138A (en) | 1995-07-25 |
| EP0445097B1 (en) | 1996-08-21 |
| ES2091903T3 (es) | 1996-11-16 |
| EP0445097A2 (en) | 1991-09-04 |
| GR3021484T3 (en) | 1997-01-31 |
| DE69121435T2 (de) | 1997-02-27 |
| JPH06245775A (ja) | 1994-09-06 |
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