DK0450742T3 - DTPA-monoamider, farmaceutiske midler, der indeholder dem, deres anvendelse og fremgangsmåde til deres fremstilling - Google Patents

DTPA-monoamider, farmaceutiske midler, der indeholder dem, deres anvendelse og fremgangsmåde til deres fremstilling

Info

Publication number
DK0450742T3
DK0450742T3 DK91250089.9T DK91250089T DK0450742T3 DK 0450742 T3 DK0450742 T3 DK 0450742T3 DK 91250089 T DK91250089 T DK 91250089T DK 0450742 T3 DK0450742 T3 DK 0450742T3
Authority
DK
Denmark
Prior art keywords
group
hydrogen atom
radical
alkyl
denote
Prior art date
Application number
DK91250089.9T
Other languages
English (en)
Inventor
Heribert Dr Schmitt-Willich
Hanns-Joachim Dr Weinmann
Heinz Dr Gries
Erich Dr Klieger
Bernd Dr Raduechel
Hubert Dr Vogler
Gabriele D Schuhmann-Giampieri
Juergen Dr Conrad
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0450742T3 publication Critical patent/DK0450742T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/12—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C07F15/025—Iron compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Pyrrole Compounds (AREA)
DK91250089.9T 1990-04-06 1991-04-05 DTPA-monoamider, farmaceutiske midler, der indeholder dem, deres anvendelse og fremgangsmåde til deres fremstilling DK0450742T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4011684A DE4011684A1 (de) 1990-04-06 1990-04-06 Dtpa-monoamide, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
DK0450742T3 true DK0450742T3 (da) 1994-11-07

Family

ID=6404192

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91250089.9T DK0450742T3 (da) 1990-04-06 1991-04-05 DTPA-monoamider, farmaceutiske midler, der indeholder dem, deres anvendelse og fremgangsmåde til deres fremstilling

Country Status (16)

Country Link
US (4) US5859214A (da)
EP (1) EP0450742B1 (da)
JP (1) JP2854159B2 (da)
AT (1) ATE108179T1 (da)
AU (1) AU644639B2 (da)
CA (1) CA2039846A1 (da)
DE (2) DE4011684A1 (da)
DK (1) DK0450742T3 (da)
ES (1) ES2057746T3 (da)
FI (1) FI911646L (da)
HU (1) HUT57180A (da)
IE (1) IE65923B1 (da)
NO (1) NO180582C (da)
NZ (1) NZ237711A (da)
PT (1) PT97263B (da)
ZA (1) ZA912550B (da)

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DE69312951T2 (de) * 1992-10-14 1997-12-11 Nycomed Imaging As Chelatpolymere
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DE4318369C1 (de) * 1993-05-28 1995-02-09 Schering Ag Verwendung von makrocyclischen Metallkomplexen als Temperatursonden
WO1995027705A1 (en) * 1994-04-08 1995-10-19 Bracco International B.V. Aromatic amide compounds and metal chelates thereof
US5582814A (en) * 1994-04-15 1996-12-10 Metasyn, Inc. 1-(p-n-butylbenzyl) DTPA for magnetic resonance imaging
US5672335A (en) * 1994-11-30 1997-09-30 Schering Aktiengesellschaft Use of metal complexes as liver and gallbladder X-ray diagnostic agents
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IL117200A0 (en) * 1995-02-21 1996-06-18 Schering Ag Diethylenetriamine-pentaacetic acid monoamide derivatives pharmaceutical compostions containing the same and processes for the preparation thereof
DE19507819A1 (de) * 1995-02-21 1996-08-22 Schering Ag DTPA-Monoamide der zentralen Carbonsäure und deren Metallkomplexe, diese Komplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik und Therapie sowie Verfahren zur Herstellung der Komplexe und Mittel
DE19507822B4 (de) * 1995-02-21 2006-07-20 Schering Ag Substituierte DTPA-Monoamide der zentralen Carbonsäure und deren Metallkomplexe, diese Komplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik und Therapie sowie Verfahren zur Herstellung der Komplexe und Mittel
DE19646762B4 (de) * 1996-11-04 2004-05-13 Schering Ag Verwendung von Metallverbindungen zur Herstellung von Mitteln zur Strahlentherapie von Tumoren
US6334995B1 (en) * 1998-03-24 2002-01-01 Council Of Scientific & Industrial Research Process for the preparation of technetium-99m diethylene triamine penta-acetic acid diester
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CN101010107A (zh) * 2004-08-26 2007-08-01 马林克罗特公司 监测肾功能的发光金属络合物
FI20065030A7 (fi) * 2006-01-17 2007-07-18 Wallac Oy Neutraaliset leimausreagenssit ja niistä johdetut konjugaatit
KR101336505B1 (ko) * 2006-08-17 2013-12-05 에픽스 파마슈티칼스, 인코포레이티드 림프계의 영상화 방법
US20110146787A1 (en) * 2008-05-28 2011-06-23 Sebastien Allen Silicon carbide-based antireflective coating
JP5681719B2 (ja) 2009-09-24 2015-03-11 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル タウ機能不全を伴う神経障害を処置するための新規な治療ターゲットとしてのｆｋｂｐ５２−タウ相互作用
EP2710381A2 (en) 2011-05-16 2014-03-26 Institut National de la Sante et de la Recherche Medicale (INSERM) Methods for screening substances capable of modulating the replication of an influenza virus
WO2014053871A1 (en) 2012-10-04 2014-04-10 INSERM (Institut National de la Santé et de la Recherche Médicale) A method for screening a compound capable of inhibiting the notch1 transcriptional activity
ES2831014T3 (es) 2014-02-18 2021-06-07 Inst Nat Sante Rech Med Métodos y composiciones farmacéuticas para el tratamiento de enfermedades mediadas por la vía de señalización del complejo NRP-1/OBR
US10189887B2 (en) 2014-04-17 2019-01-29 Inserm (Institut National De La Sante Et De La Recherche Medicale) Polypeptides and uses thereof for reducing CD95-mediated cell motility
US20200046859A1 (en) * 2017-04-27 2020-02-13 The Regents Of The University Of California Modified mri contrast agents and uses thereof
US11008354B2 (en) * 2018-05-24 2021-05-18 The Texas A&M University System Chiral solvating agents
WO2020144324A1 (en) 2019-01-11 2020-07-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for screening inhibitors against chikungunya virus and for determining whether subjects are predisposed to infection by said virus
CN115043747B (zh) * 2022-08-15 2022-11-25 康瑞鑫(天津)药物研究院有限公司 卡洛酸三钠的析晶方法及制备的卡洛酸三钠晶体

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Also Published As

Publication number Publication date
JP2854159B2 (ja) 1999-02-03
EP0450742A1 (de) 1991-10-09
US6287538B1 (en) 2001-09-11
US5859214A (en) 1999-01-12
DE4011684A1 (de) 1991-10-10
NO911345L (no) 1991-10-07
NO911345D0 (no) 1991-04-05
NZ237711A (en) 1993-12-23
NO180582C (no) 1997-05-14
IE911155A1 (en) 1991-10-09
ES2057746T3 (es) 1994-10-16
AU7418691A (en) 1991-10-10
NO180582B (no) 1997-02-03
JPH0665174A (ja) 1994-03-08
ATE108179T1 (de) 1994-07-15
HU911126D0 (en) 1991-10-28
US7074387B2 (en) 2006-07-11
CA2039846A1 (en) 1991-10-07
IE65923B1 (en) 1995-11-29
PT97263B (pt) 1998-08-31
FI911646A0 (fi) 1991-04-05
ZA912550B (en) 1992-01-29
PT97263A (pt) 1992-01-31
AU644639B2 (en) 1993-12-16
FI911646A7 (fi) 1991-10-07
HUT57180A (en) 1991-11-28
DE59102092D1 (de) 1994-08-18
FI911646L (fi) 1991-10-07
US6565830B1 (en) 2003-05-20
US20030202943A1 (en) 2003-10-30
EP0450742B1 (de) 1994-07-06

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