DK0452926T3 - 5-Aryl-4-alkyl-3H-1,2,4-triazol-3-thioner, der kan anvendes som hukommelsesforbedrende midler - Google Patents
5-Aryl-4-alkyl-3H-1,2,4-triazol-3-thioner, der kan anvendes som hukommelsesforbedrende midlerInfo
- Publication number
- DK0452926T3 DK0452926T3 DK91106219.8T DK91106219T DK0452926T3 DK 0452926 T3 DK0452926 T3 DK 0452926T3 DK 91106219 T DK91106219 T DK 91106219T DK 0452926 T3 DK0452926 T3 DK 0452926T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- thiones
- triazole
- aryl
- memory enhancers
- Prior art date
Links
- 239000003695 memory enhancer Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 208000006264 Korsakoff syndrome Diseases 0.000 abstract 1
- 201000008485 Wernicke-Korsakoff syndrome Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000019771 cognition Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51352490A | 1990-04-19 | 1990-04-19 | |
| US07/658,789 US5100906A (en) | 1990-04-19 | 1991-02-26 | 5-aryl-4-alkyl-3h-1,2,4-triazole-3-thiones useful as memory enhancers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0452926T3 true DK0452926T3 (da) | 1996-04-01 |
Family
ID=27057902
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91106219.8T DK0452926T3 (da) | 1990-04-19 | 1991-04-18 | 5-Aryl-4-alkyl-3H-1,2,4-triazol-3-thioner, der kan anvendes som hukommelsesforbedrende midler |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5100906A (da) |
| EP (1) | EP0452926B1 (da) |
| JP (1) | JP3015495B2 (da) |
| KR (1) | KR0180935B1 (da) |
| AT (1) | ATE135211T1 (da) |
| AU (1) | AU631982B2 (da) |
| DE (1) | DE69117791T2 (da) |
| DK (1) | DK0452926T3 (da) |
| IE (1) | IE71917B1 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5250558A (en) * | 1992-01-28 | 1993-10-05 | Merck & Co., Inc. | Substituted triazolinones, triazolinethiones, and triazolinimines as neurotensin antagonists used to treat psychosis |
| AU679130B2 (en) * | 1993-10-29 | 1997-06-19 | Aventis Inc. | 3-aryl-4-alkyl and 4,5-dialkyl-4H-1,2,4-triazoles useful as memory enhancers |
| US5489598A (en) * | 1994-06-08 | 1996-02-06 | Warner-Lambert Company | Cytoprotection utilizing aryltriazol-3-thiones |
| AR039385A1 (es) | 2002-04-19 | 2005-02-16 | Astrazeneca Ab | Derivados de tioxantina como inhibidores de la mieloperoxidasa |
| SE0301232D0 (sv) * | 2003-04-25 | 2003-04-25 | Astrazeneca Ab | Novel use |
| SE0402591D0 (sv) * | 2004-10-25 | 2004-10-25 | Astrazeneca Ab | Novel use |
| MY140748A (en) | 2004-12-06 | 2010-01-15 | Astrazeneca Ab | Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy |
| TW200804383A (en) | 2006-06-05 | 2008-01-16 | Astrazeneca Ab | New compounds |
| CN105218465A (zh) * | 2015-11-14 | 2016-01-06 | 刘杰 | 一种治疗乳腺癌的药物组合物 |
| WO2023080555A1 (ko) | 2021-11-02 | 2023-05-11 | 엘지전자 주식회사 | 옷걸이 및 옷걸이가 구비된 의류처리장치 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3439450A1 (de) * | 1984-10-27 | 1986-05-07 | Boehringer Ingelheim KG, 6507 Ingelheim | 1,2,4-triazolo-carbamate und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel |
| US4912095A (en) * | 1985-10-29 | 1990-03-27 | Merrell Dow Pharmaceuticals Inc. | 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones useful as antidepressants |
| US4775688A (en) * | 1985-12-11 | 1988-10-04 | Merrell Dow Pharmaceuticals Inc. | 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones and their use as antidepressants |
| EP0280867A1 (en) * | 1987-01-27 | 1988-09-07 | Merrell Dow Pharmaceuticals Inc. | Process for the preparation of 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones |
| US4847276A (en) * | 1988-09-06 | 1989-07-11 | Merrell Dow Pharmaceuticals Inc. | Treatment of thromobocytosis with 5-(4-chlorophenyl)-2,4-diemthyl-3H-1,2,4-triazole-3-thione |
-
1991
- 1991-02-26 US US07/658,789 patent/US5100906A/en not_active Expired - Fee Related
- 1991-04-15 AU AU74378/91A patent/AU631982B2/en not_active Ceased
- 1991-04-17 KR KR1019910006119A patent/KR0180935B1/ko not_active Expired - Fee Related
- 1991-04-18 EP EP91106219A patent/EP0452926B1/en not_active Expired - Lifetime
- 1991-04-18 AT AT91106219T patent/ATE135211T1/de not_active IP Right Cessation
- 1991-04-18 DE DE69117791T patent/DE69117791T2/de not_active Expired - Fee Related
- 1991-04-18 DK DK91106219.8T patent/DK0452926T3/da active
- 1991-04-18 IE IE130491A patent/IE71917B1/en not_active IP Right Cessation
- 1991-04-18 JP JP3112152A patent/JP3015495B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69117791D1 (de) | 1996-04-18 |
| ATE135211T1 (de) | 1996-03-15 |
| IE911304A1 (en) | 1991-10-23 |
| IE71917B1 (en) | 1997-03-12 |
| AU631982B2 (en) | 1992-12-10 |
| JPH04225917A (ja) | 1992-08-14 |
| KR0180935B1 (ko) | 1999-04-01 |
| US5100906A (en) | 1992-03-31 |
| EP0452926A2 (en) | 1991-10-23 |
| EP0452926A3 (en) | 1992-05-06 |
| DE69117791T2 (de) | 1996-08-01 |
| KR910018023A (ko) | 1991-11-30 |
| EP0452926B1 (en) | 1996-03-13 |
| JP3015495B2 (ja) | 2000-03-06 |
| AU7437891A (en) | 1991-10-24 |
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