ATE135211T1 - 5-aryl-4-alkyl-3h-1,2,4-triazol-3-thione zur verbesserung des gedächtnisses - Google Patents

5-aryl-4-alkyl-3h-1,2,4-triazol-3-thione zur verbesserung des gedächtnisses

Info

Publication number: ATE135211T1
Authority: AT; Austria
Prior art keywords: alkyl; triazole; thione; aryl; improve memory
Prior art date: 1990-04-19

Application number

AT91106219T

Other languages

English (en)

Inventor

Jerry A Miller

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-19

Filing date

1991-04-18

Publication date

1996-03-15

1991-04-18 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1996-03-15 Application granted granted Critical

1996-03-15 Publication of ATE135211T1 publication Critical patent/ATE135211T1/de

Links

125000000217 alkyl group Chemical group 0.000 abstract 3
208000024827 Alzheimer disease Diseases 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
208000006264 Korsakoff syndrome Diseases 0.000 abstract 1
201000008485 Wernicke-Korsakoff syndrome Diseases 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
230000019771 cognition Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT91106219T 1990-04-19 1991-04-18 5-aryl-4-alkyl-3h-1,2,4-triazol-3-thione zur verbesserung des gedächtnisses ATE135211T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US51352490A	1990-04-19	1990-04-19
US07/658,789 US5100906A (en)	1990-04-19	1991-02-26	5-aryl-4-alkyl-3h-1,2,4-triazole-3-thiones useful as memory enhancers

Publications (1)

Publication Number	Publication Date
ATE135211T1 true ATE135211T1 (de)	1996-03-15

Family

ID=27057902

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91106219T ATE135211T1 (de)	1990-04-19	1991-04-18	5-aryl-4-alkyl-3h-1,2,4-triazol-3-thione zur verbesserung des gedächtnisses

Country Status (9)

Country	Link
US (1)	US5100906A (de)
EP (1)	EP0452926B1 (de)
JP (1)	JP3015495B2 (de)
KR (1)	KR0180935B1 (de)
AT (1)	ATE135211T1 (de)
AU (1)	AU631982B2 (de)
DE (1)	DE69117791T2 (de)
DK (1)	DK0452926T3 (de)
IE (1)	IE71917B1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5250558A (en) *	1992-01-28	1993-10-05	Merck & Co., Inc.	Substituted triazolinones, triazolinethiones, and triazolinimines as neurotensin antagonists used to treat psychosis
NZ275620A (en) *	1993-10-29	1999-01-28	Merrell Pharma Inc	3-optionally substituted phenyl or naphthyl-1,2,4-triazole derivatives; pharmaceutical compositions
US5489598A (en) *	1994-06-08	1996-02-06	Warner-Lambert Company	Cytoprotection utilizing aryltriazol-3-thiones
AR039385A1 (es)	2002-04-19	2005-02-16	Astrazeneca Ab	Derivados de tioxantina como inhibidores de la mieloperoxidasa
SE0301232D0 (sv) *	2003-04-25	2003-04-25	Astrazeneca Ab	Novel use
SE0402591D0 (sv) *	2004-10-25	2004-10-25	Astrazeneca Ab	Novel use
MY140748A (en)	2004-12-06	2010-01-15	Astrazeneca Ab	Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
TW200804383A (en)	2006-06-05	2008-01-16	Astrazeneca Ab	New compounds
CN105218465A (zh) *	2015-11-14	2016-01-06	刘杰	一种治疗乳腺癌的药物组合物
WO2023080555A1 (ko)	2021-11-02	2023-05-11	엘지전자 주식회사	옷걸이 및 옷걸이가 구비된 의류처리장치

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3439450A1 (de) *	1984-10-27	1986-05-07	Boehringer Ingelheim KG, 6507 Ingelheim	1,2,4-triazolo-carbamate und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
US4912095A (en) *	1985-10-29	1990-03-27	Merrell Dow Pharmaceuticals Inc.	5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones useful as antidepressants
US4775688A (en) *	1985-12-11	1988-10-04	Merrell Dow Pharmaceuticals Inc.	5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones and their use as antidepressants
EP0280867A1 (de) *	1987-01-27	1988-09-07	Merrell Dow Pharmaceuticals Inc.	Verfahren zur Herstellung von 5-aryl-2,4-dialkyl-3H-1,2,4-triazol-3-thione
US4847276A (en) *	1988-09-06	1989-07-11	Merrell Dow Pharmaceuticals Inc.	Treatment of thromobocytosis with 5-(4-chlorophenyl)-2,4-diemthyl-3H-1,2,4-triazole-3-thione

1991
- 1991-02-26 US US07/658,789 patent/US5100906A/en not_active Expired - Fee Related
- 1991-04-15 AU AU74378/91A patent/AU631982B2/en not_active Ceased
- 1991-04-17 KR KR1019910006119A patent/KR0180935B1/ko not_active Expired - Fee Related
- 1991-04-18 EP EP91106219A patent/EP0452926B1/de not_active Expired - Lifetime
- 1991-04-18 DE DE69117791T patent/DE69117791T2/de not_active Expired - Fee Related
- 1991-04-18 IE IE130491A patent/IE71917B1/en not_active IP Right Cessation
- 1991-04-18 DK DK91106219.8T patent/DK0452926T3/da active
- 1991-04-18 AT AT91106219T patent/ATE135211T1/de not_active IP Right Cessation
- 1991-04-18 JP JP3112152A patent/JP3015495B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP3015495B2 (ja)	2000-03-06
DE69117791T2 (de)	1996-08-01
DE69117791D1 (de)	1996-04-18
EP0452926A2 (de)	1991-10-23
DK0452926T3 (da)	1996-04-01
AU631982B2 (en)	1992-12-10
EP0452926B1 (de)	1996-03-13
AU7437891A (en)	1991-10-24
EP0452926A3 (en)	1992-05-06
US5100906A (en)	1992-03-31
JPH04225917A (ja)	1992-08-14
KR0180935B1 (ko)	1999-04-01
IE911304A1 (en)	1991-10-23
KR910018023A (ko)	1991-11-30
IE71917B1 (en)	1997-03-12

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Legal Events

Date	Code	Title	Description
1996-11-15	UEP	Publication of translation of european patent specification
2005-01-15	REN	Ceased due to non-payment of the annual fee