DK0455006T3 - Substituerede 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoler - Google Patents

Substituerede 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoler

Info

Publication number: DK0455006T3
Authority: DK; Denmark
Prior art keywords: benzodioxoles; substituted; hydroxyethyl; aryl; propyl
Prior art date: 1990-05-04

Application number

DK91105510T

Other languages

Danish (da)

English (en)

Inventor

Jonathan David Bloom

Thomas Harrison Claus

Vern Gordon Devries

Jo Alene Dolan

Minu Dhanjisha Dutia

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-05-04

Filing date

1991-04-08

Publication date

1999-11-22

1991-04-08 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1999-11-22 Application granted granted Critical

1999-11-22 Publication of DK0455006T3 publication Critical patent/DK0455006T3/da

Links

125000002924 primary amino group Chemical group [H]N([H])* 0.000 title 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 title 1
150000005529 1,3-benzodioxoles Chemical class 0.000 abstract 1
241001465754 Metazoa Species 0.000 abstract 1
230000003178 anti-diabetic effect Effects 0.000 abstract 1
230000002058 anti-hyperglycaemic effect Effects 0.000 abstract 1
230000003579 anti-obesity Effects 0.000 abstract 1
239000003472 antidiabetic agent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Hematology (AREA)
Obesity (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Fodder In General (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Peptides Or Proteins (AREA)

DK91105510T 1990-05-04 1991-04-08 Substituerede 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoler DK0455006T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/519,192 US5061727A (en)	1990-05-04	1990-05-04	Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles

Publications (1)

Publication Number	Publication Date
DK0455006T3 true DK0455006T3 (da)	1999-11-22

Family

ID=24067267

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91105510T DK0455006T3 (da)	1990-05-04	1991-04-08	Substituerede 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoler

Country Status (22)

Country	Link
US (1)	US5061727A (fr)
EP (1)	EP0455006B1 (fr)
JP (1)	JPH05320153A (fr)
KR (1)	KR0181178B1 (fr)
CN (1)	CN1037348C (fr)
AT (1)	ATE181914T1 (fr)
AU (1)	AU639094B2 (fr)
CA (1)	CA2041712A1 (fr)
CZ (1)	CZ283420B6 (fr)
DE (1)	DE69131412D1 (fr)
DK (1)	DK0455006T3 (fr)
ES (1)	ES2133273T3 (fr)
FI (1)	FI94862C (fr)
HU (2)	HU210596B (fr)
IE (1)	IE911509A1 (fr)
IL (1)	IL97900A (fr)
NO (1)	NO177822C (fr)
NZ (1)	NZ237992A (fr)
PL (1)	PL165665B1 (fr)
PT (1)	PT97540B (fr)
SG (1)	SG47917A1 (fr)
ZA (1)	ZA913366B (fr)

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US5461163A (en) *	1994-06-06	1995-10-24	American Cyanamid Company	Synthesis and purification of [R-(R,R)]-5-[2-[5-(3-chloro-phenyl)-2-oxo-3-oxazolidinyl]-propyl]-1,-3-benzodiozole-2,2-dicarboxylic acid dimethyl ester
WO1995033724A1 (fr) *	1994-06-09	1995-12-14	Glaxo Group Limited	Derives phenethanolamine et leur utilisation en tant qu'agonistes atypiques du recepteur adrenergique beta
US5627200A (en) *	1994-09-26	1997-05-06	Pfizer Inc	β3 -Adrenoceptor agonists and antagonists for the treatment of intestinal motility disorders, depression, prostate disease and dyslipidemia
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EP0827746B1 (fr) *	1996-09-05	2002-04-03	Eli Lilly And Company	Analogues de carbazole étant agonistes beta3-adrénergiques sélectifs
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US5965607A (en) *	1996-12-30	1999-10-12	American Home Products Corporation	Substituted Benzo[1,4]dioxines as antiobesity agents
US6172099B1 (en)	1997-07-03	2001-01-09	Asahi Kasei Kogyo Kabushiki Kaisha	Tricyclic compounds having saturated rings and medicinal compositions containing the same
CO5011072A1 (es)	1997-12-05	2001-02-28	Lilly Co Eli	Etanolaminas pirazinil substituidas como agfonistas de los receptores
US6043253A (en) *	1998-03-03	2000-03-28	Merck & Co., Inc.	Fused piperidine substituted arylsulfonamides as β3-agonists
GB9812709D0 (en) *	1998-06-13	1998-08-12	Glaxo Group Ltd	Chemical compounds
US20030220329A1 (en) *	1999-09-17	2003-11-27	Duke University	Method of improving beta-adrenergic receptor function
KR20020069215A (ko) *	1999-12-16	2002-08-29	아사히 가세이 가부시키가이샤	신규한 치환기를 갖는 3환성 화합물
AU5257401A (en)	2000-04-28	2001-11-12	Asahi Chemical Ind	Novel bicyclic compounds
JP2002053574A (ja)	2000-08-10	2002-02-19	Nisshin Pharma Inc	１，４−ベンゾジオキサン環を有するプロパノールアミン誘導体
WO2002018363A2 (fr) *	2000-08-29	2002-03-07	Abbott Laboratories	Inhibiteurs de la proteine tyrosine phosphatase
US6472545B2 (en)	2000-08-29	2002-10-29	Abbott Laboratories	Protein tyrosine phosphatase inhibitors
US7034053B2 (en) *	2001-01-31	2006-04-25	Smithkline Beecham Corporation	Phenethanolamine derivatives, compositions, and their use as agonists at atypical beta-adrenoreceptors
GB0102407D0 (en)	2001-01-31	2001-03-14	Glaxo Group Ltd	Process
US7709677B2 (en)	2001-01-31	2010-05-04	Glaxosmithkline Llc	Process of preparing arylethanoldiamines
WO2003024483A1 (fr) *	2001-09-11	2003-03-27	Fujisawa Pharmaceutical Co., Ltd.	Potentialisateur d'effets inhibiteurs sur la frequence des mictions et l'incontinence urinaire
DE60239170D1 (de)	2001-10-25	2011-03-24	Asahi Kasei Pharma Corp	Bicyclische Verbindungen
TW200732313A (en) *	2005-12-15	2007-09-01	Astrazeneca Ab	Oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators
US8008506B2 (en)	2008-10-09	2011-08-30	Asahi Kasei Pharma Corporation	Indazole compounds
KR20110050733A (ko)	2008-10-09	2011-05-16	아사히 가세이 파마 가부시키가이샤	인다졸 유도체
US9907767B2 (en)	2010-08-03	2018-03-06	Velicept Therapeutics, Inc.	Pharmaceutical compositions and the treatment of overactive bladder
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1990
- 1990-05-04 US US07/519,192 patent/US5061727A/en not_active Expired - Lifetime
1991
- 1991-04-08 SG SG1996005341A patent/SG47917A1/en unknown
- 1991-04-08 DE DE69131412T patent/DE69131412D1/de not_active Expired - Lifetime
- 1991-04-08 EP EP91105510A patent/EP0455006B1/fr not_active Expired - Lifetime
- 1991-04-08 ES ES91105510T patent/ES2133273T3/es not_active Expired - Lifetime
- 1991-04-08 AT AT91105510T patent/ATE181914T1/de not_active IP Right Cessation
- 1991-04-08 DK DK91105510T patent/DK0455006T3/da active
- 1991-04-19 IL IL97900A patent/IL97900A/xx not_active IP Right Cessation
- 1991-04-29 AU AU76078/91A patent/AU639094B2/en not_active Ceased
- 1991-04-30 NZ NZ237992A patent/NZ237992A/en unknown
- 1991-05-02 PT PT97540A patent/PT97540B/pt not_active IP Right Cessation
- 1991-05-02 PL PL91290119A patent/PL165665B1/pl unknown
- 1991-05-02 JP JP3130413A patent/JPH05320153A/ja active Pending
- 1991-05-02 CA CA002041712A patent/CA2041712A1/fr not_active Abandoned
- 1991-05-03 NO NO911751A patent/NO177822C/no not_active IP Right Cessation
- 1991-05-03 IE IE150991A patent/IE911509A1/en unknown
- 1991-05-03 ZA ZA913366A patent/ZA913366B/xx unknown
- 1991-05-03 CZ CS911285A patent/CZ283420B6/cs not_active IP Right Cessation
- 1991-05-03 FI FI912142A patent/FI94862C/fi active
- 1991-05-03 KR KR1019910007217A patent/KR0181178B1/ko not_active Expired - Fee Related
- 1991-05-03 HU HU911495A patent/HU210596B/hu not_active IP Right Cessation
- 1991-05-04 CN CN91102965A patent/CN1037348C/zh not_active Expired - Fee Related
1995
- 1995-06-27 HU HU95P/P00457P patent/HU211607A9/hu unknown

Also Published As

Publication number	Publication date
AU639094B2 (en)	1993-07-15
US5061727A (en)	1991-10-29
PL165665B1 (pl)	1995-01-31
PL290119A1 (en)	1992-07-27
HU911495D0 (en)	1991-11-28
PT97540A (pt)	1992-01-31
EP0455006A3 (en)	1992-04-01
EP0455006A2 (fr)	1991-11-06
JPH05320153A (ja)	1993-12-03
SG47917A1 (en)	1998-04-17
FI94862B (fi)	1995-07-31
HUT59918A (en)	1992-07-28
ZA913366B (en)	1992-03-25
FI912142L (fi)	1991-11-05
CA2041712A1 (fr)	1991-11-05
HU210596B (en)	1995-05-29
NZ237992A (en)	1993-05-26
PT97540B (pt)	1998-08-31
NO177822B (no)	1995-08-21
AU7607891A (en)	1991-11-07
FI94862C (fi)	1995-11-10
FI912142A0 (fi)	1991-05-03
CS9101285A2 (en)	1991-12-17
NO177822C (no)	1995-11-29
CZ283420B6 (cs)	1998-04-15
CN1056495A (zh)	1991-11-27
NO911751D0 (no)	1991-05-03
IL97900A (en)	1997-04-15
IE911509A1 (en)	1991-11-06
ATE181914T1 (de)	1999-07-15
IL97900A0 (en)	1992-06-21
NO911751L (no)	1991-11-05
KR0181178B1 (ko)	1999-03-20
ES2133273T3 (es)	1999-09-16
HU211607A9 (en)	1995-12-28
KR910019999A (ko)	1991-12-19
EP0455006B1 (fr)	1999-07-07
CN1037348C (zh)	1998-02-11
DE69131412D1 (de)	1999-08-12

Publication	Publication Date	Title
DK0455006T3 (da)	1999-11-22	Substituerede 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoler
BR9107141A (pt)	1993-11-16	N-((1,3,5-triazin-2-il)aminocarbonil)benzenossulfonamidas herbicidas
BR9107049A (pt)	1993-09-28	Aril-haloquirazois substituidos herbicidas
FI916165A0 (fi)	1991-12-30	1,3-oxatiolannukleosidanaloger.
OA09479A (fr)	1992-11-15	"Triazolopyridines herbicides".
FI914173A7 (fi)	1992-03-06	Samextruderad cellplastkomposit.
FI952682A0 (fi)	1995-06-01	Insektisidisiä 5-substituoituja 2,4-diamiinipyrimidiinijohdannaisia
IT1252605B (it)	1995-06-19	Copoliesteri aventi una migliorata combinazione di proprieta'.
DE69102464D1 (de)	1994-07-21	Insektizide Zusammensetzung auf Basis von Bacillus Thuringiensis.
DE59104765D1 (de)	1995-04-06	Substituierte 5-Alkoxy-1,2,4-triazol-3-(thi)one.
FI904586L (fi)	1992-03-19	En metod att framstaella en vinylpolymer-polyolefinkomposit.
NO905468D0 (no)	1990-12-19	Pesticidblandinger.
DK0517660T3 (da)	1997-10-27	Benzo-1,2,3-thiadiazol-derivater.
FI915801L (fi)	1992-06-12	Komposition och foerfarande foer att foerhindra fluoros.
DE69014231D1 (de)	1995-01-05	Lichthärtendes elektrostatisches Element mit verbesserten ökologischen Eigenschaften.
FI914041A0 (fi)	1991-08-27	Vattenbaserade herbicida kompositioner av 2-(2-imidazolin-2-yl) pyridiner och -kinoliner.
DE69022560D1 (de)	1995-10-26	N,N'-hydrocarbylen-bis-(N-hals)-substituierte Amidhydrazide.
DE68900131D1 (de)	1991-08-08	Biozide 4,5-dichlor-1,2-dithiol-3-on-zusammensetzung.
TR26505A (tr)	1995-03-15	Fenil ikameli 4,5- dihidropirazoller
PL285480A1 (en)	1991-04-22	Herbicide
DE69108266D1 (de)	1995-04-27	Polyamidzusammensetzungen.
DE69120311D1 (de)	1996-07-25	Verbesserte Nylon 6.6.-Filamente
IT9034606U1 (it)	1992-03-18	Perfect 90.
FI901015A0 (fi)	1990-02-28	Karm foer skyddsrumsdoerrar eller -luckor.
IT9004006U1 (it)	1992-05-15	R g m 90.