DK0465508T3 - Diætsupplement til insulinresistente diabetikere - Google Patents

Diætsupplement til insulinresistente diabetikere

Info

Publication number: DK0465508T3
Authority: DK; Denmark
Prior art keywords: dietary supplement; insulin resistant; development; diabetics; resistant diabetics
Prior art date: 1989-03-08

Application number

DK90905048T

Other languages

English (en)

Inventor

Joseph Larner

Allison Kennington

Original Assignee

Univ Virginia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-08

Filing date

1990-03-08

Publication date

2000-08-07

1990-03-08 Application filed by Univ Virginia filed Critical Univ Virginia

2000-08-07 Application granted granted Critical

2000-08-07 Publication of DK0465508T3 publication Critical patent/DK0465508T3/da

Links

235000015872 dietary supplement Nutrition 0.000 title abstract 4
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 4
102000004877 Insulin Human genes 0.000 title abstract 2
108090001061 Insulin Proteins 0.000 title abstract 2
229940125396 insulin Drugs 0.000 title abstract 2
208000024891 symptom Diseases 0.000 abstract 3
CDAISMWEOUEBRE-LKPKBOIGSA-N 1D-chiro-inositol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O CDAISMWEOUEBRE-LKPKBOIGSA-N 0.000 abstract 1
230000001747 exhibiting effect Effects 0.000 abstract 1
CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
- A23L29/37—Sugar alcohols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Obesity (AREA)
Hematology (AREA)
Food Science & Technology (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Nutrition Science (AREA)
Endocrinology (AREA)
Polymers & Plastics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Medicines Containing Plant Substances (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK90905048T 1989-03-08 1990-03-08 Diætsupplement til insulinresistente diabetikere DK0465508T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US32048289A	1989-03-08	1989-03-08
PCT/US1990/001109 WO1990010439A1 (en)	1989-03-08	1990-03-08	Dietary supplement for insulin-resistant diabetics

Publications (1)

Publication Number	Publication Date
DK0465508T3 true DK0465508T3 (da)	2000-08-07

Family

ID=23246630

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90905048T DK0465508T3 (da)	1989-03-08	1990-03-08	Diætsupplement til insulinresistente diabetikere

Country Status (10)

Country	Link
US (1)	US5124360A (da)
EP (1)	EP0465508B1 (da)
JP (3)	JPH04504847A (da)
AT (1)	ATE193440T1 (da)
AU (1)	AU647735B2 (da)
CA (1)	CA2047686C (da)
DE (1)	DE69033560T2 (da)
DK (1)	DK0465508T3 (da)
ES (1)	ES2146197T3 (da)
WO (1)	WO1990010439A1 (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5428066A (en) *	1989-03-08	1995-06-27	Larner; Joseph	Method of reducing elevated blood sugar in humans
GB9020544D0 (en) *	1990-09-20	1990-10-31	Sandoz Ltd	Improvements in or relating to organic compounds
JPH06504278A (ja) *	1991-01-23	1994-05-19	ユニヴァーシティ　オヴ　ヴァージニア　アラムナイ　パテンツ　ファウンデイション	ヒトの高い血糖値を低下させる方法
JPH0665080A (ja) *	1992-03-10	1994-03-08	Godo Shiyusei Kk	α−グルコシダ−ゼ阻害剤を含有する、過血糖付随疾患の予防・治療剤、および保健食
US5420108A (en) *	1992-09-14	1995-05-30	Shohet; Isaac H.	Method of controlling diabetes mellitus
TW282398B (da) *	1993-12-22	1996-08-01	Bristol Myers Squibb Co
US5652221A (en) *	1994-11-07	1997-07-29	The University Of Virginia Patent Foundation	Method of treating defective glucose metabolism using synthetic insulin substances
US5550166A (en) *	1995-03-17	1996-08-27	Ostlund; Richard E.	Pinitol and derivatives thereof for the treatment of metabolic disorders
RU2121353C1 (ru) *	1995-05-29	1998-11-10	Иван Петрович Чепурной	Способ коррекции углеводного обмена в организме человека (варианты)
US6086882A (en) *	1997-08-06	2000-07-11	National Institute For Pharmaceutical Research	Phytodrug for management of peptic ulcer and methods of preparing and using same
DE19707756A1 (de) *	1997-02-26	1998-08-27	Georgios Dr Pandalis	Präparat auf der Basis von Kichererbsenpflanzen oder -pflanzenteilen
IL132032A0 (en) *	1997-03-24	2001-03-19	Galderma Res & Dev	Retinoid related molecules for the treatment of non-insulin dependent diabetes mellitus
US6492341B1 (en)	1997-05-07	2002-12-10	Cornell Research Foundation, Inc.	Preparation of fagopyritols and uses therefor
CA2236641C (en) *	1997-05-07	2008-07-15	Cornell Research Foundation, Inc.	Preparation of fagopyritols and uses therefor
US20010039297A1 (en) *	1998-05-19	2001-11-08	Insmed Pharmaceuticals, Inc.	Compositions and method for improving insulin sensivity and glucose metabolism in individuals with impaired fasting glucose or impaired glucose tolerance
US6518318B1 (en)	1999-05-20	2003-02-11	Charles E. Weeks	Stimulating transport of glucose into animal tissue by the administration of pinitol
WO2001028356A2 (en) *	1999-10-18	2001-04-26	Muscletech Research And Development Inc.	Food supplement for increasing lean mass and strength
US6784209B1 (en) *	1999-10-18	2004-08-31	Muscletech Research And Development Inc.	Food supplement for increasing lean mass and strength
WO2001062237A2 (en)	2000-02-23	2001-08-30	Orentreich Foundation For The Advancement Of Science, Inc.	Compositions for the treatment of alopecia and other disorders of the pilosebaceous apparatus
KR20010091341A (ko) *	2000-03-14	2001-10-23	신용철	카이로이노시톨 추출물을 유효성분으로 함유하는 의약조성물
US6660891B2 (en) *	2000-05-15	2003-12-09	Insmed Incorporated	Methods for the production of D-chiro-inositol and the use of D-chiro inositol obtained therefrom
US6486127B1 (en) *	2001-05-23	2002-11-26	Insmed, Incorporated	Compositions comprising D-chiro inositol and lipid lowering compounds and methods of treatment thereof
US6492339B1 (en) *	2001-05-23	2002-12-10	Insmed, Incorporated	Compositions comprising D-chiro inositol and sulfonylureas and methods of treatment thereof
JP2006501859A (ja)	2002-05-09	2006-01-19	コーネルリサーチファンデーション，インコーポレーティッド	ファゴピリトールシンターゼ遺伝子およびその使用法
US20060258754A1 (en) *	2004-05-28	2006-11-16	Joseph Larner	Method of treating endothelial dysfunction, oxidative stress and related diseases
US20060004096A1 (en) *	2004-05-28	2006-01-05	Joseph Larner	Method of Treating Endothelial Dysfunction, Oxidative Stress and Related Diseases
JP2007068476A (ja) *	2005-09-08	2007-03-22	Hokko Chem Ind Co Ltd	健康食品およびｄ−キロ−イノシトールを得る方法
US20110218176A1 (en)	2006-11-01	2011-09-08	Barbara Brooke Jennings-Spring	Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
US20080103116A1 (en) *	2006-11-01	2008-05-01	Jennings-Spring Barbara L	Method of treatment and compositions of D-chiro inositol and phosphates thereof
US20090214474A1 (en) *	2006-11-01	2009-08-27	Barbara Brooke Jennings	Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
AR074797A1 (es) *	2008-10-10	2011-02-16	Japan Tobacco Inc	Compuesto de fluoreno , composiciones farmaceuticas , inhibidores de pdhk y pdhk2 , metodos de tratamiento , usos de los mismos y kit comercial
ITMI20110445A1 (it) *	2011-03-22	2012-09-23	Lo Li Pharma Srl	Formulazione farmaceutica comprendente inositolo.
WO2017188393A1 (ja) *	2016-04-27	2017-11-02	小林製薬株式会社	育毛剤
EP3530267B1 (en)	2016-10-06	2021-12-29	DY Natural Co., Ltd	Composition comprising pinitol for use in the prevention or treatment of female menopausal symptoms
US11898184B2 (en)	2017-09-07	2024-02-13	Sweet Sense Inc.	Low glycemic sugar composition
NZ765637A (en)	2017-11-23	2025-11-28	Biosearch S A	Method for increasing embryo implantation rate in a female subject suffering polycystic ovary syndrome

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE465951B (sv) *	1984-10-23	1991-11-25	Perstorp Ab	Isomer av inositoltrifosfat foeretraedesvis i saltform foer anvaendning som terapeutiskt eller profylaktiskt medel samt kompositioner daerav
SE464059C (sv) *	1988-09-15	1997-06-02	Perstorp Ab	Användning av inositoltrifosfat för framställning av läkemedel
JPH03138126A (ja) *	1989-10-24	1991-06-12	Mitsubishi Gas Chem Co Inc	均一薄肉中空成形品の射出成形方法

1990
- 1990-03-08 AU AU52808/90A patent/AU647735B2/en not_active Ceased
- 1990-03-08 JP JP2504805A patent/JPH04504847A/ja active Pending
- 1990-03-08 ES ES90905048T patent/ES2146197T3/es not_active Expired - Lifetime
- 1990-03-08 CA CA002047686A patent/CA2047686C/en not_active Expired - Fee Related
- 1990-03-08 DK DK90905048T patent/DK0465508T3/da active
- 1990-03-08 DE DE69033560T patent/DE69033560T2/de not_active Expired - Fee Related
- 1990-03-08 EP EP90905048A patent/EP0465508B1/en not_active Expired - Lifetime
- 1990-03-08 WO PCT/US1990/001109 patent/WO1990010439A1/en not_active Ceased
- 1990-03-08 AT AT90905048T patent/ATE193440T1/de not_active IP Right Cessation
1991
- 1991-03-21 US US07/672,778 patent/US5124360A/en not_active Expired - Lifetime
1999
- 1999-06-09 JP JP11163145A patent/JP2000219624A/ja active Pending
2002
- 2002-02-06 JP JP2002029603A patent/JP2002249427A/ja active Pending

Also Published As

Publication number	Publication date
AU5280890A (en)	1990-10-09
DE69033560D1 (de)	2000-07-06
JP2002249427A (ja)	2002-09-06
EP0465508B1 (en)	2000-05-31
JP2000219624A (ja)	2000-08-08
US5124360A (en)	1992-06-23
EP0465508A4 (en)	1992-05-13
WO1990010439A1 (en)	1990-09-20
DE69033560T2 (de)	2001-03-01
JPH04504847A (ja)	1992-08-27
ES2146197T3 (es)	2000-08-01
CA2047686C (en)	2000-09-05
ATE193440T1 (de)	2000-06-15
CA2047686A1 (en)	1990-09-09
EP0465508A1 (en)	1992-01-15
AU647735B2 (en)	1994-03-31

Publication	Publication Date	Title
DK0465508T3 (da)	2000-08-07	Diætsupplement til insulinresistente diabetikere
Walshe	1951	OBSERVATIONS ON THE SYMPTOMATOLOGY AND PATHOGENESIS OF HEPATIC COMA1
Sullivan Jr et al.	1981	Acute carbamazepine toxicity resulting from overdose
DK642587D0 (da)	1987-12-08	Insulinpraeparat
ES2060199T3 (es)	1994-11-16	Forma galenica para administrar oralmente glipicida hipoglicemica.
Sullivan et al.	1978	Enkephalin in peripheral neuroendocrine tumours
Goodhart et al.	1938	The role of nutritional deficiencies in the production of cardiovascular disturbances in the alcohol addict
Craig et al.	1966	Infants, toddlers, and aspirin
Melander et al.	1983	Clinical pharmacology of glipizide
Nayyar et al.	1972	Fixed drug eruption to oxyphenbutazone and phenylbutazone
Alderman	1974	Analgesics in the acute phase of myocardial infarction
RU96115219A (ru)	1998-10-27	Способ лечения больных сахарным диабетом
Miller	1966	Hypoghycaemic effect of oxytetracycline
Jones et al.	1939	Alcoholic Beri-beri Heart
Hultgren et al.	1952	Clinical and experimental study of use of khellin in treatment of angina pectoris
Silverstone	1986	Clinical use of appetite suppressants.
Begg	1955	Sulphaemoglobinaemia
JPS56108712A (en)	1981-08-28	Lecithin cholesterol acyl transferase activator
ROBINSON et al.	1924	THE THERAPEUTIC USE OF DIGITALIS: WITH ESPECIAL REFERENCE TO ITS INTRAVENOUS INJECTION
Wilhelmsen	1978	Beta-blockers and plasma triglycerides
Spesivtseva et al.	1987	Use of high-purity insulins in the treatment of patients with diabetes mellitus
Corbus	1964	Enteric coated thyroid as a cause of relapse in Myxedema
STRYKER et al.	1945	Determination of macrocytic anemia as an aid in diagnosis of certain deficiency dermatoses
KAYE et al.	1966	Antipyretics in patients with juvenile diabetes mellitus: comparison of salicylate and a salicylate substitute (experimental preparation PAJ-102)
Maggioni	1948	Salicylate therapy in children