ZA916060B - Lowering of blood uric acid levels - Google Patents

Lowering of blood uric acid levels

Info

Publication number: ZA916060B
Authority: ZA; South Africa
Prior art keywords: uric acid; acid levels; blood uric; lowering; hydroxy
Prior art date: 1990-08-02

Application number

ZA916060A

Other languages

English (en)

Inventor

Paden C Going

C Going Paden

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-02

Filing date

1991-08-01

Publication date

1993-03-31

1991-08-01 Application filed by Pfizer filed Critical Pfizer

1993-03-31 Publication of ZA916060B publication Critical patent/ZA916060B/xx

Links

LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 title abstract 2
TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 title abstract 2
239000008280 blood Substances 0.000 title abstract 2
210000004369 blood Anatomy 0.000 title abstract 2
229940116269 uric acid Drugs 0.000 title abstract 2
201000005569 Gout Diseases 0.000 abstract 2
241000124008 Mammalia Species 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
206010018634 Gouty Arthritis Diseases 0.000 abstract 1
235000011054 acetic acid Nutrition 0.000 abstract 1
150000001242 acetic acid derivatives Chemical class 0.000 abstract 1
150000001243 acetic acids Chemical class 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
239000000651 prodrug Chemical group 0.000 abstract 1
229940002612 prodrug Drugs 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

ZA916060A 1990-08-02 1991-08-01 Lowering of blood uric acid levels ZA916060B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/562,096 US5064830A (en)	1990-08-02	1990-08-02	Lowering of blood uric acid levels

Publications (1)

Publication Number	Publication Date
ZA916060B true ZA916060B (en)	1993-03-31

Family

ID=24244779

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA916060A ZA916060B (en)	1990-08-02	1991-08-01	Lowering of blood uric acid levels

Country Status (16)

Country	Link
US (1)	US5064830A (da)
EP (1)	EP0469837B1 (da)
JP (1)	JPH04234321A (da)
KR (1)	KR940002665B1 (da)
AT (1)	ATE113840T1 (da)
AU (1)	AU622590B2 (da)
CA (1)	CA2048235C (da)
DE (1)	DE69105069T2 (da)
DK (1)	DK0469837T3 (da)
HU (1)	HUT61665A (da)
IE (1)	IE64046B1 (da)
IL (1)	IL98979A (da)
MX (1)	MX9100450A (da)
NZ (1)	NZ239215A (da)
PT (1)	PT98509B (da)
ZA (1)	ZA916060B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5391551A (en) *	1993-05-10	1995-02-21	Pfizer Inc.	Method of lowering blood lipid levels
IL120264A0 (en) *	1996-02-29	1997-06-10	Pfizer	Method of reducing tissue damage associated with non-cardiac ischemia
IL124236A (en) *	1997-05-05	2003-01-12	Pfizer	Pharmaceutical composition for treating or reversing diabetic cardiomyopathy comprising aldose reductase inhibitor
WO2011046800A1 (en) *	2009-10-13	2011-04-21	Wellstat Therapeutics Corporation	3-substituted compounds for reducing uric acid
WO2017176777A1 (en) *	2016-04-04	2017-10-12	Aviragen Therapeutics, Inc.	Bta-c585 for the treatment and/or prevention of conditions related to or associated with hyperuricemia or hyperuricosuria and other conditions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL80475A (en) *	1985-11-07	1993-01-31	Pfizer	Heterocyclic-substituted 4-oxo (or thio)-3h- phthalazinyl-acetic acid derivatives and pharmaceutical compositions containing them
US4939140A (en) *	1985-11-07	1990-07-03	Pfizer Inc.	Heterocyclic oxophthalazinyl acetic acids
GB8704569D0 (en) *	1987-02-26	1987-04-01	Ici America Inc	Therapeutic agent
JPH0676391B2 (ja) *	1987-06-09	1994-09-28	フアイザー・インコーポレイテツド	ベンゾチアゾール等の複素環側鎖を有するオキソフタラジニル酢酸類の製造方法
EP0322153A3 (en) *	1987-12-21	1990-08-16	Pfizer Inc.	Heterocyclic oxophtalazinyl acetic acids

1990
- 1990-08-02 US US07/562,096 patent/US5064830A/en not_active Expired - Lifetime
1991
- 1991-07-27 IL IL9897991A patent/IL98979A/en not_active IP Right Cessation
- 1991-07-29 DE DE69105069T patent/DE69105069T2/de not_active Expired - Fee Related
- 1991-07-29 DK DK91306944.9T patent/DK0469837T3/da active
- 1991-07-29 EP EP91306944A patent/EP0469837B1/en not_active Expired - Lifetime
- 1991-07-29 AT AT91306944T patent/ATE113840T1/de not_active IP Right Cessation
- 1991-07-31 CA CA002048235A patent/CA2048235C/en not_active Expired - Fee Related
- 1991-07-31 MX MX9100450A patent/MX9100450A/es unknown
- 1991-07-31 PT PT98509A patent/PT98509B/pt active IP Right Grant
- 1991-08-01 HU HU912567A patent/HUT61665A/hu unknown
- 1991-08-01 KR KR1019910013330A patent/KR940002665B1/ko not_active Expired - Fee Related
- 1991-08-01 JP JP3193231A patent/JPH04234321A/ja active Pending
- 1991-08-01 ZA ZA916060A patent/ZA916060B/xx unknown
- 1991-08-01 IE IE272191A patent/IE64046B1/en not_active IP Right Cessation
- 1991-08-01 AU AU81560/91A patent/AU622590B2/en not_active Ceased
- 1991-08-01 NZ NZ239215A patent/NZ239215A/en unknown

Also Published As

Publication number	Publication date
AU622590B2 (en)	1992-04-09
EP0469837A2 (en)	1992-02-05
PT98509B (pt)	1999-01-29
KR940002665B1 (ko)	1994-03-28
US5064830A (en)	1991-11-12
AU8156091A (en)	1992-02-06
IL98979A0 (en)	1992-07-15
DE69105069T2 (de)	1995-03-09
EP0469837B1 (en)	1994-11-09
NZ239215A (en)	1997-07-27
IE912721A1 (en)	1992-02-12
DE69105069D1 (de)	1994-12-15
CA2048235C (en)	1995-05-30
KR920003970A (ko)	1992-03-27
IE64046B1 (en)	1995-06-28
MX9100450A (es)	1992-04-01
HUT61665A (en)	1993-03-01
ATE113840T1 (de)	1994-11-15
JPH04234321A (ja)	1992-08-24
EP0469837A3 (en)	1992-04-08
IL98979A (en)	1996-11-14
DK0469837T3 (da)	1994-12-27
HU912567D0 (en)	1992-01-28
PT98509A (pt)	1992-06-30

Publication	Publication Date	Title
TW268942B (da)	1996-01-21
DE68920654D1 (de)	1995-03-02	4-Oxochinolin-3-carbonsäure-Derivate, ihre Herstellung und ihre Verwendung.
FI873631A0 (fi)	1987-08-21	--alkyl-4-amino-3-kinolinmetanoler och 1-(4-aralkylamino-3-kinolinyl)alkanoler, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
NO934792L (no)	1994-06-27	Xantinderivater
DK0632036T3 (da)	2000-06-05	Amidderivater med antipypercholesteræmisk aktivitet, deres fremstilling og deres terapeutiske anvendelser
DE69305344D1 (de)	1996-11-14	Antianginale purinone
NZ332136A (en)	1999-08-30	Phenylalkylcarboxylic acid derivatives useful for treating hyperglycemia
AU1302388A (en)	1988-09-15	Method of treating anxiety with tetrahydrobenz(c,d)indole-6- carboxamides
AU622590B2 (en)	1992-04-09	Lowering of blood uric acid levels
AU605493B2 (en)	1991-01-17	Novel 8-(lower alkyl) bicyclo{4.2.0}-octane derivatives with valuable therapeutic properties
EP0393534A3 (de)	1992-02-26	Pharmazeutisch wirksame Pteridinderivate
ES2042727T3 (es)	1993-12-16	Acidos 1,3,4,9-tetrahidropirano(3,4-b)indol-1-acetico.
DE3777724D1 (de)	1992-04-30	2-amino-3-aroyl-gamma-oxobenzolbuttersaeure und ihre ester.
AU8488391A (en)	1992-04-09	Piperazine derivatives