DK0470192T3 - Forbedret immunoassay, der indbefatter lyofiliseret reaktantblanding - Google Patents
Forbedret immunoassay, der indbefatter lyofiliseret reaktantblandingInfo
- Publication number
- DK0470192T3 DK0470192T3 DK90908003.8T DK90908003T DK0470192T3 DK 0470192 T3 DK0470192 T3 DK 0470192T3 DK 90908003 T DK90908003 T DK 90908003T DK 0470192 T3 DK0470192 T3 DK 0470192T3
- Authority
- DK
- Denmark
- Prior art keywords
- polyethylene glycol
- mixture
- isooctylphenyl ether
- reactant mixture
- sugar
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000003018 immunoassay Methods 0.000 title abstract 2
- 239000000376 reactant Substances 0.000 title abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 6
- 229920001223 polyethylene glycol Polymers 0.000 abstract 6
- ORLFVWPPBMVPNZ-UHFFFAOYSA-N 1-(6-methylheptyl)-4-[4-(6-methylheptyl)phenoxy]benzene Chemical compound C1=CC(CCCCCC(C)C)=CC=C1OC1=CC=C(CCCCCC(C)C)C=C1 ORLFVWPPBMVPNZ-UHFFFAOYSA-N 0.000 abstract 3
- 239000003599 detergent Substances 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 abstract 1
- 229920001353 Dextrin Polymers 0.000 abstract 1
- 239000004375 Dextrin Substances 0.000 abstract 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 abstract 1
- 238000005054 agglomeration Methods 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 abstract 1
- 235000019425 dextrin Nutrition 0.000 abstract 1
- 239000010931 gold Substances 0.000 abstract 1
- 229910052737 gold Inorganic materials 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 239000004816 latex Substances 0.000 abstract 1
- 229920000126 latex Polymers 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/963—Methods of stopping an enzyme reaction or stabilizing the test materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/344,575 US5102788A (en) | 1988-11-21 | 1989-04-28 | Immunoassay including lyophilized reactant mixture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0470192T3 true DK0470192T3 (da) | 1997-10-27 |
Family
ID=23351108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90908003.8T DK0470192T3 (da) | 1989-04-28 | 1990-04-16 | Forbedret immunoassay, der indbefatter lyofiliseret reaktantblanding |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5102788A (da) |
| EP (1) | EP0470192B1 (da) |
| JP (1) | JP2823353B2 (da) |
| AT (1) | ATE159047T1 (da) |
| CA (1) | CA2053885A1 (da) |
| DE (1) | DE69031561T2 (da) |
| DK (1) | DK0470192T3 (da) |
| ES (1) | ES2110415T3 (da) |
| WO (1) | WO1990013637A1 (da) |
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| GB8826429D0 (en) * | 1988-11-11 | 1988-12-14 | Univ Leeds Ind Service Ltd | Enzyme stabilisation systems |
| US5376556A (en) * | 1989-10-27 | 1994-12-27 | Abbott Laboratories | Surface-enhanced Raman spectroscopy immunoassay |
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| DE4034509A1 (de) * | 1990-10-30 | 1992-05-07 | Boehringer Mannheim Gmbh | Immunologisches praezipitationsverfahren zur bestimmung eines bindefaehigen analyten sowie reagenz zur durchfuehrung dieses verfahrens |
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| CA2119125A1 (en) * | 1991-10-11 | 1993-04-15 | Sharon M. Devereaux | Unit-of-use reagent compositions for specific binding assays |
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| JP4142095B2 (ja) * | 1994-06-02 | 2008-08-27 | クアドラント・ドラツグ・デリバリー・リミテツド | 各種物質の再水和または融解時の凝集を防止する方法及び該方法により得られる組成物 |
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| US7141436B2 (en) * | 1999-11-03 | 2006-11-28 | Science And Technology Corp. | Immunoassay and reagents and kits for performing the same |
| US6699722B2 (en) | 2000-04-14 | 2004-03-02 | A-Fem Medical Corporation | Positive detection lateral-flow apparatus and method for small and large analytes |
| AT5044U1 (de) * | 2001-05-10 | 2002-02-25 | Medsystems Diagnostics Gmbh | Quantitativer einschritt immuntest in lyophilisierter form |
| US20030017620A1 (en) * | 2001-06-21 | 2003-01-23 | Carron Keith T. | Lyophilization of colloidal metals for surface enhanced Raman scattering |
| US7776610B2 (en) * | 2003-05-07 | 2010-08-17 | University Of Wyoming | Cyanide and related species detection with metal surfaces |
| DE10323901A1 (de) * | 2003-05-26 | 2005-01-05 | Institut Virion/Serion Gmbh | Verfahren und Testmittel zur Untersuchung und/oder zum Nachweis von Biomolekülen und/oder Wirkstoffen in Flüssigkeitsproben |
| US20040241879A1 (en) * | 2003-06-02 | 2004-12-02 | Robinson Joseph R. | Assay device and method |
| US7993933B2 (en) * | 2004-05-06 | 2011-08-09 | University Of Wyoming | Cyanide and related species detection with metal surfaces |
| CA2587945A1 (en) * | 2004-11-17 | 2007-04-12 | Bioveris | Electrochemiluminescent assay |
| US20060275841A1 (en) * | 2004-12-20 | 2006-12-07 | Martin Blankfard | Assay method and apparatus with reduced sample matrix effects |
| US7763418B2 (en) * | 2005-07-05 | 2010-07-27 | Cytoskeleton, Inc. | Detection of Rho proteins |
| GB0701253D0 (en) | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
| US7738094B2 (en) | 2007-01-26 | 2010-06-15 | Becton, Dickinson And Company | Method, system, and compositions for cell counting and analysis |
| US7816135B2 (en) | 2007-07-05 | 2010-10-19 | Becton, Dickinson And Company | Method of analyzing lymphocytes |
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| US8377643B2 (en) * | 2009-03-16 | 2013-02-19 | Abaxis, Inc. | Split flow device for analyses of specific-binding partners |
| US8039272B2 (en) * | 2009-04-01 | 2011-10-18 | Nova Biomedical | Rapid quantification assay involving concentrated and ligand-coated gold colloid |
| CN102004146B (zh) * | 2009-09-03 | 2014-09-10 | 艾博生物医药(杭州)有限公司 | 一种混合标记物质和标记方法及其应用 |
| EP2513650A4 (en) | 2009-12-17 | 2013-12-18 | Abay Sa | NEW ANALYTE DETECTION ASSAYS IN SAMPLES AND KITS AND COMPOSITIONS RELATING THERETO |
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| US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
| EP3411499B1 (en) | 2016-02-05 | 2023-11-08 | Gen-Probe Incorporated | Dried amplification compositions |
| JP6801381B2 (ja) * | 2016-11-07 | 2020-12-16 | 東ソー株式会社 | 凍結乾燥状態の検体前処理試薬 |
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| US4459359A (en) * | 1981-11-19 | 1984-07-10 | New York Blood Center, Inc. | Sensitive immunoassays of antigens or antibodies sequestered within immune complexes |
| US4458014A (en) * | 1982-01-11 | 1984-07-03 | Forsyth Dental Infirmary For Children | Serological method for the identification of microorganisms |
| US4681782A (en) * | 1982-03-31 | 1987-07-21 | Biostar Medical Products, Inc. | Article for determining the presence of immune complexes |
| US4503143A (en) * | 1982-08-20 | 1985-03-05 | Btc Diagnostics Limited Partnership | Enzyme immunoassay with two-part solution of tetramethylbenzidine as chromogen |
| US4457916A (en) * | 1982-08-31 | 1984-07-03 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for stabilizing Tumor Necrosis Factor and a stable aqueous solution or powder containing the same |
| US4459358A (en) * | 1982-12-29 | 1984-07-10 | Polaroid Corporation | Multilayer element for analysis |
| JPS6035263A (ja) * | 1983-08-05 | 1985-02-23 | Wako Pure Chem Ind Ltd | 不溶性担体に固定化された免疫活性物質の安定化法及び該物質を構成単位として含む生理活性物質測定用試薬 |
| US4545452A (en) * | 1983-09-26 | 1985-10-08 | Caterpillar Tractor Co. | Axle housing mounting bracket |
| GB8328918D0 (en) * | 1983-10-28 | 1983-11-30 | Unilever Plc | Alkaline phosphatase |
| US4615972A (en) * | 1983-11-04 | 1986-10-07 | Immuno Concepts, Inc. | Stabilization of indicators for detecting enzyme activity |
| US4931385A (en) * | 1985-06-24 | 1990-06-05 | Hygeia Sciences, Incorporated | Enzyme immunoassays and immunologic reagents |
| DE3682047D1 (de) * | 1985-07-09 | 1991-11-21 | Quadrant Bioresources Ltd | Beschuetzung von proteinen und aehnlichem. |
| US4853335A (en) * | 1987-09-28 | 1989-08-01 | Olsen Duane A | Colloidal gold particle concentration immunoassay |
| US4859612A (en) * | 1987-10-07 | 1989-08-22 | Hygeia Sciences, Inc. | Metal sol capture immunoassay procedure, kit for use therewith and captured metal containing composite |
| DE68920693T2 (de) * | 1988-03-30 | 1995-05-24 | Toray Industries | Gefriergetrocknete Zusammensetzung, die ein mit Meerrettichperoxydase markiertes Fab'-Fragment eines gegen menschliches Beta-Interferon gerichteten Antikörpers und Trehalose enthält; EIA Kit, der diese Zusammensetzung enthält. |
-
1989
- 1989-04-28 US US07/344,575 patent/US5102788A/en not_active Expired - Fee Related
-
1990
- 1990-04-16 WO PCT/US1990/002064 patent/WO1990013637A1/en not_active Ceased
- 1990-04-16 DK DK90908003.8T patent/DK0470192T3/da active
- 1990-04-16 AT AT90908003T patent/ATE159047T1/de not_active IP Right Cessation
- 1990-04-16 JP JP2506814A patent/JP2823353B2/ja not_active Expired - Lifetime
- 1990-04-16 ES ES90908003T patent/ES2110415T3/es not_active Expired - Lifetime
- 1990-04-16 DE DE69031561T patent/DE69031561T2/de not_active Expired - Fee Related
- 1990-04-16 EP EP90908003A patent/EP0470192B1/en not_active Expired - Lifetime
- 1990-04-16 CA CA002053885A patent/CA2053885A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2053885A1 (en) | 1990-10-29 |
| DE69031561D1 (de) | 1997-11-13 |
| JPH05500854A (ja) | 1993-02-18 |
| ATE159047T1 (de) | 1997-10-15 |
| EP0470192A1 (en) | 1992-02-12 |
| ES2110415T3 (es) | 1998-02-16 |
| DE69031561T2 (de) | 1998-02-19 |
| WO1990013637A1 (en) | 1990-11-15 |
| JP2823353B2 (ja) | 1998-11-11 |
| EP0470192B1 (en) | 1997-10-08 |
| EP0470192A4 (en) | 1992-03-11 |
| US5102788A (en) | 1992-04-07 |
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