DK0471236T3 - Imidazopyridinderivater og deres anvendelse - Google Patents
Imidazopyridinderivater og deres anvendelseInfo
- Publication number
- DK0471236T3 DK0471236T3 DK91112798.3T DK91112798T DK0471236T3 DK 0471236 T3 DK0471236 T3 DK 0471236T3 DK 91112798 T DK91112798 T DK 91112798T DK 0471236 T3 DK0471236 T3 DK 0471236T3
- Authority
- DK
- Denmark
- Prior art keywords
- imidazopyridine derivatives
- chem
- compound
- formula
- composition containing
- Prior art date
Links
- 125000004857 imidazopyridinyl group Chemical class N1C(=NC2=C1C=CC=N2)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 102000000584 Calmodulin Human genes 0.000 abstract 1
- 108010041952 Calmodulin Proteins 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20296390 | 1990-07-30 | ||
| JP20296490 | 1990-07-30 | ||
| JP12127791 | 1991-05-27 | ||
| JP14018691 | 1991-06-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0471236T3 true DK0471236T3 (da) | 1995-07-24 |
Family
ID=27470767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91112798.3T DK0471236T3 (da) | 1990-07-30 | 1991-07-30 | Imidazopyridinderivater og deres anvendelse |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US5244908A (da) |
| EP (1) | EP0471236B1 (da) |
| AT (1) | ATE119774T1 (da) |
| CA (1) | CA2048110C (da) |
| DE (1) | DE69108138T2 (da) |
| DK (1) | DK0471236T3 (da) |
| ES (1) | ES2069137T3 (da) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5350758A (en) * | 1992-07-08 | 1994-09-27 | Merrell Dow Pharmaceuticals Inc. | Piperidyl sulfonamides and sulfoxamides as inhibitors of cholesterol biosynthesis |
| JP3545461B2 (ja) * | 1993-09-10 | 2004-07-21 | エーザイ株式会社 | 二環式ヘテロ環含有スルホンアミド誘導体 |
| US5698518A (en) * | 1994-03-30 | 1997-12-16 | Oklahoma Medical Research Foundation | Method for regulating inflammation and tumor growth with calmodulin, calmodulin analogues or calmodulin antagonists |
| CA2191979A1 (en) * | 1994-06-20 | 1995-12-28 | Muneo Takatani | Condensed imidazole compounds, their production and use |
| DE69733815T2 (de) | 1996-02-15 | 2006-06-08 | Biosense Webster, Inc., Diamond Bar | Sonde zur exkavation |
| US6235731B1 (en) | 1996-04-24 | 2001-05-22 | Takeda Chemical Industries, Ltd. | Fused imidazopyridine derivatives as antihyperlipidemic agents |
| DE19624704A1 (de) * | 1996-06-20 | 1998-01-08 | Klinge Co Chem Pharm Fab | Neue Pyridylalkansäureamide |
| DE19624659A1 (de) | 1996-06-20 | 1998-01-08 | Klinge Co Chem Pharm Fab | Neue Pyridylalken- und Pyridylalkinsäureamide |
| US6451816B1 (en) | 1997-06-20 | 2002-09-17 | Klinge Pharma Gmbh | Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression |
| US6443974B1 (en) * | 1996-07-28 | 2002-09-03 | Biosense, Inc. | Electromagnetic cardiac biostimulation |
| BR9712792A (pt) * | 1996-08-28 | 1999-12-14 | Procter & Gamble | Inibidores de metaloprotease bidentada. |
| DE19756212A1 (de) | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue, mit einem cyclischen Imid substituierte Pyridylalkan-, alken- und -alkincarbonsäureamide |
| US6903118B1 (en) | 1997-12-17 | 2005-06-07 | Klinge Pharma Gmbh | Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides |
| DE19756261A1 (de) * | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue arylsubstituierte Pyridylalkan-, alken- und alkincarbonsäureamide |
| DE19756235A1 (de) | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue piperidinylsubstituierte Pyridylalkan- alken- und -alkincarbonsäureamide |
| US20030113303A1 (en) * | 1998-02-05 | 2003-06-19 | Yitzhack Schwartz | Homing of embryonic stem cells to a target zone in tissue using active therapeutics or substances |
| US20030129750A1 (en) * | 1998-02-05 | 2003-07-10 | Yitzhack Schwartz | Homing of donor cells to a target zone in tissue using active therapeutics or substances |
| ES2255155T3 (es) | 1998-02-05 | 2006-06-16 | Biosense Webster, Inc. | Dispositivo para la administracion intracardiaca de farmacos. |
| EP1031564A1 (en) | 1999-02-26 | 2000-08-30 | Klinge Pharma GmbH | Inhibitors of cellular nicotinamide mononucleotide formation and their use in cancer therapy |
| EP1076091A1 (en) * | 1999-08-09 | 2001-02-14 | Universite Catholique De Louvain | Medicament for the prevention and/or the treatment of ischemic heart and peripheral vascular diseases, tumour and wounds |
| AU2001241512A1 (en) | 2000-03-13 | 2001-09-24 | Eli Lilly And Company | Sulfonamide derivatives |
| DE10117184A1 (de) * | 2001-04-05 | 2002-10-17 | Gruenenthal Gmbh | Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen |
| EP1758895A1 (en) | 2004-06-17 | 2007-03-07 | Wyeth a Corporation of the State of Delaware | Gonadotropin releasing hormone receptor antagonists |
| BRPI0512239A (pt) | 2004-06-17 | 2008-02-19 | Wyeth Corp | processos para preparação de antagonistas de receptores de hormÈnios liberadores de gonatropina |
| US7534796B2 (en) | 2005-02-18 | 2009-05-19 | Wyeth | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor |
| US7538113B2 (en) | 2005-02-18 | 2009-05-26 | Wyeth | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
| US7582634B2 (en) | 2005-02-18 | 2009-09-01 | Wyeth | 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
| US7531542B2 (en) | 2005-05-18 | 2009-05-12 | Wyeth | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor |
| US7582636B2 (en) | 2005-05-26 | 2009-09-01 | Wyeth | Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor |
| RU2764243C2 (ru) | 2017-09-22 | 2022-01-14 | ДЖУБИЛАНТ ЭПИПЭД ЭлЭлСи | Гетероциклические соединения в качестве ингибиторов PAD |
| CN111225915B (zh) | 2017-10-18 | 2023-03-07 | 朱比兰特埃皮帕德有限公司 | 作为pad抑制剂的咪唑并吡啶化合物 |
| US11629135B2 (en) | 2017-11-06 | 2023-04-18 | Jubilant Prodell Llc | Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation |
| RS65576B1 (sr) | 2017-11-24 | 2024-06-28 | Jubilant Episcribe Llc | Heterociklična jedinjenja kao inhibitori prmt5 |
| CN112105610B (zh) | 2018-03-13 | 2024-01-26 | 朱比连特普罗德尔有限责任公司 | 作为pd1/pd-l1相互作用/活化的抑制剂的双环化合物 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3509167A (en) * | 1967-09-18 | 1970-04-28 | Pfizer & Co C | Certain 3-nitroimidazo-(1,2-a)pyridines |
| US4177274A (en) * | 1975-12-09 | 1979-12-04 | Merck & Co., Inc. | Substituted imidazo [1,2-a] pyridines |
| US4096264A (en) * | 1975-12-09 | 1978-06-20 | Merck & Co., Inc. | Certain substituted imidazo [1,2-a] pyridines |
| US4166851A (en) * | 1977-05-16 | 1979-09-04 | Merck & Co., Inc. | Certain imidazo(1,2a)pyridine derivatives |
| US4210653A (en) * | 1978-06-27 | 1980-07-01 | Merck & Co., Inc. | Pyridyloxypropanolamines |
| US4409226A (en) * | 1981-10-05 | 1983-10-11 | Schering Corporation | Imidazo[1,5-a]pyridines |
| DE3446778A1 (de) * | 1984-12-21 | 1986-07-03 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
| ATE103923T1 (de) * | 1985-12-13 | 1994-04-15 | Takeda Chemical Industries Ltd | Antibakterielle verbindungen, ihre herstellung und verwendung. |
| JPS6310792A (ja) * | 1986-03-10 | 1988-01-18 | Takeda Chem Ind Ltd | 新規セフエム化合物 |
| JP2519054B2 (ja) * | 1986-06-09 | 1996-07-31 | 武田薬品工業株式会社 | 新規セフェム化合物 |
| US4833149A (en) * | 1986-09-22 | 1989-05-23 | Ortho Pharmaceutical Corporation | 2- or 3-aryl substituted imidazo[1,2-a]pyridines |
| US4831041A (en) * | 1986-11-26 | 1989-05-16 | Fujisawa Pharmaceutical Co., Ltd. | Imidazopyridine compounds and processes for preparation thereof |
| GB8722488D0 (en) * | 1987-09-24 | 1987-10-28 | Fujisawa Pharmaceutical Co | Imidazopyridine compound |
-
1991
- 1991-07-30 CA CA002048110A patent/CA2048110C/en not_active Expired - Fee Related
- 1991-07-30 US US07/736,957 patent/US5244908A/en not_active Expired - Fee Related
- 1991-07-30 DK DK91112798.3T patent/DK0471236T3/da active
- 1991-07-30 ES ES91112798T patent/ES2069137T3/es not_active Expired - Lifetime
- 1991-07-30 DE DE69108138T patent/DE69108138T2/de not_active Expired - Fee Related
- 1991-07-30 EP EP91112798A patent/EP0471236B1/en not_active Expired - Lifetime
- 1991-07-30 AT AT91112798T patent/ATE119774T1/de active
-
1993
- 1993-06-09 US US08/074,292 patent/US5395839A/en not_active Expired - Fee Related
-
1995
- 1995-02-10 US US08/387,010 patent/US5587383A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2048110C (en) | 2002-06-25 |
| US5395839A (en) | 1995-03-07 |
| DE69108138T2 (de) | 1995-07-06 |
| US5587383A (en) | 1996-12-24 |
| EP0471236B1 (en) | 1995-03-15 |
| US5244908A (en) | 1993-09-14 |
| EP0471236A1 (en) | 1992-02-19 |
| ES2069137T3 (es) | 1995-05-01 |
| DE69108138D1 (de) | 1995-04-20 |
| CA2048110A1 (en) | 1992-01-31 |
| ATE119774T1 (de) | 1995-04-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69108138D1 (de) | Imidazopyridinderivate und ihre Verwendung. | |
| DK0563345T3 (da) | Nye 4-arylpiperaziner og 4-arylpiperidiner | |
| DE69325944D1 (de) | s-Triazinderivate als Lichtschutzmittel | |
| ATE269290T1 (de) | Benzoylderivate | |
| ES2088537T3 (es) | Derivados de piranil cianoguanidina. | |
| DK0444659T3 (da) | Farmaceutisk opløsning indeholdende derivater af FK 506 | |
| FI920023A0 (fi) | Heteroarylpiperazinfoereningar som antipsykotiska aemnen. | |
| DK0429627T3 (da) | Derivater af quinolin-3-carboxanilider | |
| DE69511424D1 (de) | Antifungale sordaridinderivate | |
| DK328188A (da) | Pyridinderivater, deres fremstilling og laegemidler indeholdende forbindelserne | |
| SE9100920D0 (sv) | New active compounds | |
| DE68903226D1 (de) | Dideoxydidehydrocarbocyclische nukleoside. | |
| NZ229861A (en) | 2,5,6-trisubstituted pyridine-3-carboxylic acids and acid derivatives | |
| DK21287A (da) | Penemderivater | |
| FI901277A0 (fi) | 2,5,6,7-tetranor-4,8-inter-m-fenylen pg1z-derivativ. | |
| DK23089D0 (da) | Thioformamidderivater og deres anvendelse | |
| FI930092A0 (fi) | Indanopyrrolidinkarbamater | |
| NO893039L (no) | Bruk av imidazopyrazol-derivater som analgesiske og antiinflammatoriske midler. | |
| EP0574271A3 (da) | ||
| DK656889A (da) | Azabicykliske derivater | |
| DK0538517T3 (da) | Nye organo-tinforbindelser med antitumoraktivitet og antitumormidler | |
| AU2639388A (en) | 2-cyano-2-aryl-1-(azole-1-yl)- ethane derivatives |