DK0473435T3 - Mono-N,N-dimethyl-4-aminopyridinium-sn-glycerol-3-phosphat, fremstilling og anvendelse deraf til fremstilling af phosphatidsyrer - Google Patents
Mono-N,N-dimethyl-4-aminopyridinium-sn-glycerol-3-phosphat, fremstilling og anvendelse deraf til fremstilling af phosphatidsyrerInfo
- Publication number
- DK0473435T3 DK0473435T3 DK91307922.4T DK91307922T DK0473435T3 DK 0473435 T3 DK0473435 T3 DK 0473435T3 DK 91307922 T DK91307922 T DK 91307922T DK 0473435 T3 DK0473435 T3 DK 0473435T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- glycerol
- phosphate
- aminopyridinium
- mono
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- AWUCVROLDVIAJX-GSVOUGTGSA-N sn-glycerol 3-phosphate Chemical compound OC[C@@H](O)COP(O)(O)=O AWUCVROLDVIAJX-GSVOUGTGSA-N 0.000 title abstract 3
- 150000008103 phosphatidic acids Chemical class 0.000 title 1
- 239000012266 salt solution Substances 0.000 abstract 2
- PORPENFLTBBHSG-MGBGTMOVSA-N 1,2-dihexadecanoyl-sn-glycerol-3-phosphate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=O)OC(=O)CCCCCCCCCCCCCCC PORPENFLTBBHSG-MGBGTMOVSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229960004979 fampridine Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/577,351 US5166351A (en) | 1989-08-18 | 1990-08-31 | Mono-N,N-dimethyl-4-aminopyridinium sn-glycerol-3-phosphate derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0473435T3 true DK0473435T3 (da) | 1995-09-11 |
Family
ID=24308339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91307922.4T DK0473435T3 (da) | 1990-08-31 | 1991-08-29 | Mono-N,N-dimethyl-4-aminopyridinium-sn-glycerol-3-phosphat, fremstilling og anvendelse deraf til fremstilling af phosphatidsyrer |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5166351A (da) |
| EP (1) | EP0473435B1 (da) |
| JP (1) | JPH04270295A (da) |
| AT (1) | ATE125258T1 (da) |
| DE (1) | DE69111340T2 (da) |
| DK (1) | DK0473435T3 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7299805B2 (en) * | 2002-06-07 | 2007-11-27 | Marctec, Llc | Scaffold and method for implanting cells |
| JP2012140330A (ja) * | 2010-12-28 | 2012-07-26 | Tosoh Corp | 水溶性リン酸エステルの精製方法 |
-
1990
- 1990-08-31 US US07/577,351 patent/US5166351A/en not_active Expired - Fee Related
-
1991
- 1991-08-29 DE DE69111340T patent/DE69111340T2/de not_active Expired - Fee Related
- 1991-08-29 EP EP91307922A patent/EP0473435B1/en not_active Expired - Lifetime
- 1991-08-29 DK DK91307922.4T patent/DK0473435T3/da active
- 1991-08-29 AT AT91307922T patent/ATE125258T1/de not_active IP Right Cessation
- 1991-08-30 JP JP3220303A patent/JPH04270295A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0473435A1 (en) | 1992-03-04 |
| US5166351A (en) | 1992-11-24 |
| EP0473435B1 (en) | 1995-07-19 |
| DE69111340T2 (de) | 1996-01-18 |
| DE69111340D1 (de) | 1995-08-24 |
| ATE125258T1 (de) | 1995-08-15 |
| JPH04270295A (ja) | 1992-09-25 |
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