DK0473961T3 - Immunoassay-reagenser og fremgangsmåde til bestemmelse af cyklosporin - Google Patents

Immunoassay-reagenser og fremgangsmåde til bestemmelse af cyklosporin

Info

Publication number
DK0473961T3
DK0473961T3 DK91113328.8T DK91113328T DK0473961T3 DK 0473961 T3 DK0473961 T3 DK 0473961T3 DK 91113328 T DK91113328 T DK 91113328T DK 0473961 T3 DK0473961 T3 DK 0473961T3
Authority
DK
Denmark
Prior art keywords
cyclosporine
determination
cyclosporin
amino acid
disclosed
Prior art date
Application number
DK91113328.8T
Other languages
Danish (da)
English (en)
Inventor
Elizabeth A Simpson
Marjorie A Morrison
Victoria P Meucci
Steven E Lunetta
Mariola B Zajac
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK0473961T3 publication Critical patent/DK0473961T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK91113328.8T 1990-08-15 1991-08-08 Immunoassay-reagenser og fremgangsmåde til bestemmelse af cyklosporin DK0473961T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56784290A 1990-08-15 1990-08-15

Publications (1)

Publication Number Publication Date
DK0473961T3 true DK0473961T3 (da) 1996-07-01

Family

ID=24268868

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91113328.8T DK0473961T3 (da) 1990-08-15 1991-08-08 Immunoassay-reagenser og fremgangsmåde til bestemmelse af cyklosporin

Country Status (10)

Country Link
US (2) US5489668A (de)
EP (1) EP0473961B1 (de)
JP (1) JP3171460B2 (de)
AT (1) ATE132504T1 (de)
AU (1) AU642035B2 (de)
CA (1) CA2049089C (de)
DE (1) DE69116034T2 (de)
DK (1) DK0473961T3 (de)
ES (1) ES2084069T3 (de)
GR (1) GR3019512T3 (de)

Families Citing this family (34)

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US5352803A (en) * 1992-03-30 1994-10-04 Abbott Laboratories 5(6)-methyl substituted fluorescein derivatives
WO1993020442A1 (en) * 1992-03-30 1993-10-14 Abbott Laboratories Reagents and methods for the detection and quantification of thyroxine in fluid samples
USRE40596E1 (en) * 1993-04-08 2008-12-02 Novartis Ag Rapamycin assay
GB9307491D0 (en) * 1993-04-08 1993-06-02 Sandoz Ltd Organic compounds
US7279561B1 (en) 1993-04-23 2007-10-09 Wyeth Anti-rapamycin monoclonal antibodies
ES2295093T3 (es) 1993-04-23 2008-04-16 Wyeth Conjugados y anticuerpos de rapamicina.
US5504091A (en) * 1993-04-23 1996-04-02 American Home Products Corporation Biotin esters of rapamycin
US5393891A (en) * 1993-06-08 1995-02-28 The Du Pont Merck Pharmaceutical Company Immunoassay reagents and methods for detecting brequinar and analogs
US5650288A (en) * 1995-07-14 1997-07-22 Macfarlane; Gordon D. Immunophilin-bound immunosuppressant assay
AU750245B2 (en) 1997-10-08 2002-07-11 Aurinia Phamaceuticals Inc. Deuterated cyclosporine analogs and their use as immunomodulating agents
US20030220234A1 (en) 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
US5990274A (en) 1997-11-25 1999-11-23 Dade Behring Inc. Cyclosporine derivatives and uses thereof
US6972339B2 (en) * 2001-09-07 2005-12-06 Epoch Biosciences, Inc. Compounds and methods for fluorescent labeling
US8569516B2 (en) 2001-09-07 2013-10-29 Elitech Holding B.V. Compounds and methods for fluorescent labeling
WO2003033526A2 (en) 2001-10-19 2003-04-24 Isotechnika Inc. Synthesis of cyclosporin analogs
KR100444698B1 (ko) * 2001-11-08 2004-08-21 한국과학기술연구원 면역복합체 단일검출시약, 그의 제조방법 및 그를 이용한농약의 검출방법
JP2006524232A (ja) 2003-03-17 2006-10-26 アルバニー モレキュラー リサーチ インコーポレーティッド 新規サイクロスポリン
EP1804823A4 (de) 2004-09-29 2010-06-09 Amr Technology Inc Neue cyclosporin-analoga und ihre pharmazeutischen anwendungen
JP2008514701A (ja) 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキン類似体およびそれらの薬学的使用
US7361636B2 (en) 2004-10-06 2008-04-22 Amr Technology, Inc. Cyclosporin alkynes and their utility as pharmaceutical agents
US8022188B2 (en) * 2006-04-24 2011-09-20 Abbott Laboratories Immunosuppressant binding antibodies and methods of obtaining and using same
US7883855B2 (en) * 2006-07-21 2011-02-08 Abbott Laboratories Immunosuppressant drug extraction reagent for immunoassays
US7576057B2 (en) 2006-11-20 2009-08-18 Scynexis, Inc. Cyclic peptides
WO2008082984A2 (en) 2006-12-29 2008-07-10 Abbott Laboratories Non-denaturing lysis reagent for use with capture-in-solution immunoassay
ES2405364T3 (es) * 2006-12-29 2013-05-30 Abbott Laboratories Ensayo diagnóstico para la detección de una molécula o fármaco en sangre entera
US7914999B2 (en) * 2006-12-29 2011-03-29 Abbott Laboratories Non-denaturing lysis reagent
JP4968611B2 (ja) 2006-12-29 2012-07-04 アボット・ラボラトリーズ 免疫抑制剤の改善された測定法
JP5174898B2 (ja) 2007-05-24 2013-04-03 アボット・ラボラトリーズ 疎水性薬物検体代謝産物との交差反応性が低下している免疫アッセイ
CN101946179B (zh) * 2007-12-19 2014-08-13 雅培制药有限公司 用于免疫分析的免疫抑制剂药物提取试剂
US20090170218A1 (en) * 2008-01-02 2009-07-02 Dade Behring Inc. Methods for detection of cyclosporin a
CN110320364B (zh) * 2018-03-30 2023-03-31 洛阳普泰生物技术有限公司 一种双抗夹心胶体金检测试剂盒、及其制备方法与应用
KR20230009394A (ko) 2020-04-17 2023-01-17 아이덱스 래보러토리즈, 인코포레이티드 형광 소광 면역검정
JP7755932B2 (ja) * 2021-01-08 2025-10-17 Ｔｉａｎｍａ Ｊａｐａｎ株式会社 蛍光偏光免疫分析用支持体、蛍光偏光免疫分析用キットおよび蛍光偏光免疫分析法

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CA1023287A (en) * 1972-12-08 1977-12-27 Boehringer Mannheim G.M.B.H. Process for the preparation of carrier-bound proteins
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
DE2819094A1 (de) * 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
CY1915A (en) * 1984-10-04 1985-09-27 Sandoz Ag Cyclosporins
US5169773A (en) * 1984-10-04 1992-12-08 Sandoz Ltd. Monoclonal antibodies to cyclosporins
US4727035A (en) * 1984-11-14 1988-02-23 Mahoney Walter C Immunoassay for cyclosporin
US5124457A (en) * 1986-05-21 1992-06-23 Abbott Laboratories Phencyclidine and phencyclidine metabolites assay, tracers, immunogens and antibodies
US4939264A (en) * 1986-07-14 1990-07-03 Abbott Laboratories Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies
EP0283801A3 (de) * 1987-03-27 1990-05-30 Abbott Laboratories Fluoreszenz-Polarisations-Test für Cyclosporin A und Metaboliten und verwandte Immunogene und Antikörper
US5427960A (en) * 1987-03-27 1995-06-27 Abbott Laboratories Fluorescence polarization assay for cyclosporin A and metabolites and related immunogens and antibodies
US5239057A (en) * 1987-03-27 1993-08-24 Abbott Laboratories Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
EP0329184A3 (de) * 1988-02-19 1990-05-23 Neorx Corporation Antimere und antimere Konjugation

Also Published As

Publication number Publication date
ATE132504T1 (de) 1996-01-15
US5489668A (en) 1996-02-06
CA2049089A1 (en) 1992-02-16
EP0473961A3 (en) 1993-04-14
DE69116034T2 (de) 1996-06-20
DE69116034D1 (de) 1996-02-15
EP0473961A2 (de) 1992-03-11
CA2049089C (en) 2002-09-03
AU642035B2 (en) 1993-10-07
US5750413A (en) 1998-05-12
JP3171460B2 (ja) 2001-05-28
ES2084069T3 (es) 1996-05-01
EP0473961B1 (de) 1996-01-03
GR3019512T3 (en) 1996-07-31
JPH04253999A (ja) 1992-09-09
AU8247191A (en) 1992-02-20

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