DK0479871T3 - Nye D-vitaminanaloger - Google Patents

Nye D-vitaminanaloger

Info

Publication number: DK0479871T3
Authority: DK; Denmark
Prior art keywords: formula; compounds; hydroxyl group; carbons; diseases
Prior art date: 1989-06-29

Application number

DK90910609.8T

Other languages

English (en)

Inventor

Ernst Torndal Binderup

Martin John Calverley

Original Assignee

Leo Pharm Prod Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-29

Filing date

1990-06-19

Publication date

1993-06-14

1990-06-19 Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd

1993-06-14 Application granted granted Critical

1993-06-14 Publication of DK0479871T3 publication Critical patent/DK0479871T3/da

Links

229930003316 Vitamin D Natural products 0.000 title 1
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title 1
235000019166 vitamin D Nutrition 0.000 title 1
239000011710 vitamin D Substances 0.000 title 1
150000003710 vitamin D derivatives Chemical class 0.000 title 1
229940046008 vitamin d Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
208000002874 Acne Vulgaris Diseases 0.000 abstract 1
201000004384 Alopecia Diseases 0.000 abstract 1
208000023275 Autoimmune disease Diseases 0.000 abstract 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
206010020772 Hypertension Diseases 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
229910019142 PO4 Inorganic materials 0.000 abstract 1
201000004681 Psoriasis Diseases 0.000 abstract 1
230000002159 abnormal effect Effects 0.000 abstract 1
206010000496 acne Diseases 0.000 abstract 1
230000032683 aging Effects 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
231100000360 alopecia Toxicity 0.000 abstract 1
208000006673 asthma Diseases 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
125000002837 carbocyclic group Chemical group 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
230000024245 cell differentiation Effects 0.000 abstract 1
230000004663 cell proliferation Effects 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
229910052731 fluorine Inorganic materials 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
208000027866 inflammatory disease Diseases 0.000 abstract 1
239000010452 phosphate Substances 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)

DK90910609.8T 1989-06-29 1990-06-19 Nye D-vitaminanaloger DK0479871T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898914963A GB8914963D0 (en)	1989-06-29	1989-06-29	Chemical compounds

Publications (1)

Publication Number	Publication Date
DK0479871T3 true DK0479871T3 (da)	1993-06-14

Family

ID=10659278

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90910609.8T DK0479871T3 (da)	1989-06-29	1990-06-19	Nye D-vitaminanaloger

Country Status (15)

Country	Link
EP (1)	EP0479871B1 (da)
JP (1)	JP2807086B2 (da)
KR (1)	KR100195573B1 (da)
AT (1)	ATE88465T1 (da)
AU (1)	AU629666B2 (da)
CA (1)	CA2051418C (da)
DE (1)	DE69001437T2 (da)
DK (1)	DK0479871T3 (da)
ES (1)	ES2055438T3 (da)
FI (1)	FI93723C (da)
GB (1)	GB8914963D0 (da)
IE (1)	IE63665B1 (da)
NZ (1)	NZ234216A (da)
WO (1)	WO1991000271A1 (da)
ZA (1)	ZA905043B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8915770D0 (en) *	1989-07-10	1989-08-31	Leo Pharm Prod Ltd	Chemical compounds
US5030772A (en) *	1990-02-14	1991-07-09	Deluca Hector F	Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) *	1990-02-14	1993-11-09	Wisconsin Alumni Research Foundation	Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
GB9017890D0 (en) *	1990-08-15	1990-09-26	Leo Pharm Prod Ltd	Chemical compounds i
CA2062520C (en) *	1991-03-11	1998-08-11	Hector F. Deluca	Synthesis of 1-alpha-hydroxy-secosterol compounds
US5486509A (en) *	1991-06-28	1996-01-23	University Of Miami	Method of preventing and treating chemotherapy-induced alopecia
DK0566030T3 (da) *	1992-04-14	2000-04-25	Kuraray Co	Fremgangsmåde til fremstilling af en optisk aktiv olefin
AU666563B2 (en) *	1992-08-07	1996-02-15	Wisconsin Alumni Research Foundation	Preparation of 19-nor-vitamin D compounds
IL107185A (en) *	1992-10-06	1998-02-22	Schering Ag	Vitamin d, 25-carboxylic acid derivatives and pharmaceutical compositions containing the same
US5552392A (en) *	1993-11-03	1996-09-03	Wisconsin Alumni Research Foundation	Method of treating hypoparathyroidism with (20S) vitamin D compounds
GB9524812D0 (en) *	1995-12-05	1996-02-07	Leo Pharm Prod Ltd	Chemical compounds
US5939408A (en) *	1996-05-23	1999-08-17	Hoffman-La Roche Inc.	Vitamin D3 analogs
SG70009A1 (en) *	1996-05-23	2000-01-25	Hoffmann La Roche	Vitamin d3 analogs
GB9622590D0 (en) *	1996-10-30	1997-01-08	Leo Pharm Prod Ltd	Chemical compounds
US20030018017A1 (en) *	2001-01-25	2003-01-23	Deluca Hector F.	Method of treatment of type I diabetes
US8377913B2 (en) *	2007-11-20	2013-02-19	Abbvie Inc.	Vitamin D receptor activators and methods of making
CA2744591A1 (en) *	2008-11-26	2010-06-03	Cytochroma Inc.	Method for synthesizing vitamin d analogs
ES2674336B1 (es) *	2016-12-28	2019-04-11	Laboratorios Vinas S A	Procedimiento para reducir derivados carbonilicos de vitamina d y uso correspondiente

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL193245C (nl) *	1983-05-09	1999-04-02	Wisconsin Alumni Res Found	Aan 1Ó,25-dihydroxyvitamine D2 verwante verbinding en farmaceutisch preparaat met een het calciummetabolisme regulerende werking dat een dergelijke verbinding bevat.
JPH0699454B2 (ja) *	1988-04-29	1994-12-07	ウィスコンシン・アルムナイ・リサーチ・ファウンデイション	１α―ヒドロキシビタミンＤ同族体
US4851401A (en) *	1988-07-14	1989-07-25	Wisconsin Alumni Research Foundation	Novel cyclopentano-vitamin D analogs

1989
- 1989-06-29 GB GB898914963A patent/GB8914963D0/en active Pending
1990
- 1990-06-06 IE IE202790A patent/IE63665B1/en not_active IP Right Cessation
- 1990-06-19 AT AT90910609T patent/ATE88465T1/de not_active IP Right Cessation
- 1990-06-19 DK DK90910609.8T patent/DK0479871T3/da active
- 1990-06-19 ES ES90910609T patent/ES2055438T3/es not_active Expired - Lifetime
- 1990-06-19 CA CA002051418A patent/CA2051418C/en not_active Expired - Fee Related
- 1990-06-19 JP JP2509936A patent/JP2807086B2/ja not_active Expired - Fee Related
- 1990-06-19 DE DE9090910609T patent/DE69001437T2/de not_active Expired - Fee Related
- 1990-06-19 EP EP90910609A patent/EP0479871B1/en not_active Expired - Lifetime
- 1990-06-19 AU AU59637/90A patent/AU629666B2/en not_active Ceased
- 1990-06-19 WO PCT/DK1990/000156 patent/WO1991000271A1/en not_active Ceased
- 1990-06-25 NZ NZ234216A patent/NZ234216A/xx unknown
- 1990-06-28 ZA ZA905043A patent/ZA905043B/xx unknown
1991
- 1991-11-07 KR KR1019910701542A patent/KR100195573B1/ko not_active Expired - Fee Related
- 1991-12-27 FI FI916150A patent/FI93723C/fi active

Also Published As

Publication number	Publication date
EP0479871A1 (en)	1992-04-15
KR920701147A (ko)	1992-08-11
JP2807086B2 (ja)	1998-09-30
FI916150A0 (fi)	1991-12-27
FI93723C (fi)	1995-05-26
CA2051418A1 (en)	1990-12-30
AU5963790A (en)	1991-01-17
IE902027L (en)	1990-12-29
ZA905043B (en)	1991-05-29
AU629666B2 (en)	1992-10-08
KR100195573B1 (en)	1999-06-15
EP0479871B1 (en)	1993-04-21
GB8914963D0 (en)	1989-08-23
CA2051418C (en)	2002-02-05
NZ234216A (en)	1993-03-26
FI93723B (fi)	1995-02-15
IE902027A1 (en)	1991-06-19
IE63665B1 (en)	1995-05-31
WO1991000271A1 (en)	1991-01-10
DE69001437T2 (de)	1993-08-19
JPH04506351A (ja)	1992-11-05
ES2055438T3 (es)	1994-08-16
ATE88465T1 (de)	1993-05-15
DE69001437D1 (de)	1993-05-27

Publication	Publication Date	Title
DK0482100T3 (da)	1994-11-07	Nye D-vitamin analoger
ES2055438T3 (es)	1994-08-16	Nuevos analogos de vitamina d.
DK0460032T3 (da)	1994-06-06	Nye D-vitaminanaloger
CA2078555A1 (en)	1992-02-16	Novel vitamin d analogues
KR920703527A (ko)	1992-12-18	신규한 비타민 d 동족체
ES2000823A6 (es)	1988-03-16	Metodo para la produccion de compuestos analogos a la vitamina d
DK0460034T3 (da)	1994-05-30	Nye D-vitaminanaloger
DK0506794T3 (da)	1994-09-26	Nye D-vitaminanaloger
PT906276E (pt)	2002-12-31	Novos analogos da vitamina d
MX9601163A (es)	1997-02-28	Nuevos compuestos derivados de cromeno.
AR006315A1 (es)	1999-08-25	Derivados de 1,25 dihidroxi-16,22,23-trisdehidro-colecalciferol, compuestos intermediarios para su exclusivo uso en el procedimiento de obtencion de dichoscompuestos, composicion farmaceutica que los contiene, procedimiento de preparación de dichos derivados y empleo de dichos derivados para preparar
ES536139A0 (es)	1985-06-01	Procedimiento para la preparacion de quinolinonas-4
ES2109019T3 (es)	1998-01-01	Derivados de dibenzo(b,e)oxepina, procedimiento para su preparacion y medicamentos que los contienen.
JPS56169656A (en)	1981-12-26	Bis(substituted phenoxyacetic acid)-n- alkyldialkanolamine, its manufacture and brain trouble treating agent containing it as major component