DK0480455T3 - Optisk aktive thienotriazolodiazepinforbindelser - Google Patents

Optisk aktive thienotriazolodiazepinforbindelser

Info

Publication number
DK0480455T3
DK0480455T3 DK91117375.5T DK91117375T DK0480455T3 DK 0480455 T3 DK0480455 T3 DK 0480455T3 DK 91117375 T DK91117375 T DK 91117375T DK 0480455 T3 DK0480455 T3 DK 0480455T3
Authority
DK
Denmark
Prior art keywords
carbon atoms
alkyl
optically active
hydrogen
active thienotriazolodiazepine
Prior art date
Application number
DK91117375.5T
Other languages
English (en)
Inventor
Minoru Moriwaki
Syuji Yuasa
Hiroyuki Kitani
Michio Terasawa
Original Assignee
Yoshitomi Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yoshitomi Pharmaceutical filed Critical Yoshitomi Pharmaceutical
Application granted granted Critical
Publication of DK0480455T3 publication Critical patent/DK0480455T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK91117375.5T 1990-10-12 1991-10-11 Optisk aktive thienotriazolodiazepinforbindelser DK0480455T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP27445190 1990-10-12
JP21451291 1991-07-31

Publications (1)

Publication Number Publication Date
DK0480455T3 true DK0480455T3 (da) 1997-02-10

Family

ID=26520357

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91117375.5T DK0480455T3 (da) 1990-10-12 1991-10-11 Optisk aktive thienotriazolodiazepinforbindelser

Country Status (9)

Country Link
US (1) US5286858A (da)
EP (1) EP0480455B1 (da)
JP (1) JP2959598B2 (da)
KR (1) KR940006633B1 (da)
AT (1) ATE148122T1 (da)
CA (1) CA2053123A1 (da)
DE (1) DE69124330T2 (da)
DK (1) DK0480455T3 (da)
ES (1) ES2099114T3 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0638560A4 (en) * 1991-10-11 1995-03-29 Yoshitomi Pharmaceutical MEDICINE FOR OSTEOPOROSIS AND DIAZEPINE COMPOUND *.
CA2573481A1 (en) * 2004-07-13 2006-01-19 Taiho Pharmaceutical Co., Ltd. Method of evaluating evenness of suplatast tosilate crystal, even crystal, and process for producing the same
AR084070A1 (es) 2010-12-02 2013-04-17 Constellation Pharmaceuticals Inc Inhibidores del bromodominio y usos de los mismos
US9249161B2 (en) 2010-12-02 2016-02-02 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
WO2012151512A2 (en) 2011-05-04 2012-11-08 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
EP2721031B1 (en) 2011-06-17 2016-01-20 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
TWI602820B (zh) 2012-06-06 2017-10-21 星宿藥物公司 溴域抑制劑及其用途
EP2864336B1 (en) 2012-06-06 2016-11-23 Constellation Pharmaceuticals, Inc. Benzo[b]isoxazoloazepine bromodomain inhibitors and uses thereof
CA2952830C (en) 2014-06-20 2022-11-01 Constellation Pharmaceuticals, Inc. Crystalline forms of 2-((4s)-6-(4-chlorophenyl)-1-methyl-4h-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide
WO2023117914A1 (en) 2021-12-22 2023-06-29 Boehringer Ingelheim International Gmbh Cyclopentathiophene carboxamide derivatives as platelet activating factor receptor antagonists

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3777541D1 (de) * 1986-11-17 1992-04-23 Yoshitomi Pharmaceutical Paf-antagonistische thienotriazoldiazepin-verbindungen und deren pharmazeutische anwendung.
WO1988009333A1 (fr) * 1987-05-28 1988-12-01 Yoshitomi Pharmaceutical Industries, Ltd. Compose a base de thieno(triazolo)diazepine et applications medicales de ce compose
MC1999A1 (fr) * 1987-12-18 1990-01-26 Hoffmann La Roche Composes tricycliques
CA1324863C (en) * 1988-01-30 1993-11-30 Welfide Corporation Thienotriazolodiazepine compounds and pharmaceutical uses thereof
DE4010528A1 (de) * 1990-04-02 1991-10-17 Boehringer Ingelheim Kg Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine

Also Published As

Publication number Publication date
JP2959598B2 (ja) 1999-10-06
KR940006633B1 (ko) 1994-07-23
EP0480455B1 (en) 1997-01-22
DE69124330T2 (de) 1997-07-03
JPH0586067A (ja) 1993-04-06
CA2053123A1 (en) 1992-04-13
DE69124330D1 (de) 1997-03-06
ATE148122T1 (de) 1997-02-15
ES2099114T3 (es) 1997-05-16
EP0480455A1 (en) 1992-04-15
KR920008048A (ko) 1992-05-27
US5286858A (en) 1994-02-15

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