DK0514452T4 - Anvendelse af insulin-sensibiliserende midler til behandling af hypertension - Google Patents

Anvendelse af insulin-sensibiliserende midler til behandling af hypertension

Info

Publication number: DK0514452T4
Authority: DK; Denmark
Prior art keywords: insulin; treat hypertension; sensitizing agents; hypertension; sensitizing
Prior art date: 1990-02-09

Application number

DK91904163T

Other languages

Danish (da)

English (en)

Other versions

DK0514452T3 (da

Inventor

Jerry R Colca

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-09

Filing date

1991-01-23

Publication date

2000-09-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23898474&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0514452(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1991-01-23 Application filed by Upjohn Co filed Critical Upjohn Co

1993-11-29 Application granted granted Critical

1993-11-29 Publication of DK0514452T3 publication Critical patent/DK0514452T3/da

2000-09-18 Publication of DK0514452T4 publication Critical patent/DK0514452T4/da

Links

206010020772 Hypertension Diseases 0.000 title abstract 2
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 4
102000004877 Insulin Human genes 0.000 abstract 2
108090001061 Insulin Proteins 0.000 abstract 2
229940125396 insulin Drugs 0.000 abstract 2
HYAFETHFCAUJAY-UHFFFAOYSA-N pioglitazone Chemical compound N1=CC(CC)=CC=C1CCOC(C=C1)=CC=C1CC1C(=O)NC(=O)S1 HYAFETHFCAUJAY-UHFFFAOYSA-N 0.000 abstract 2
239000003795 chemical substances by application Substances 0.000 abstract 1
YZFWTZACSRHJQD-UHFFFAOYSA-N ciglitazone Chemical compound C=1C=C(CC2C(NC(=O)S2)=O)C=CC=1OCC1(C)CCCCC1 YZFWTZACSRHJQD-UHFFFAOYSA-N 0.000 abstract 1
229950009226 ciglitazone Drugs 0.000 abstract 1
229960005095 pioglitazone Drugs 0.000 abstract 1
230000001235 sensitizing effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK91904163T 1990-02-09 1991-01-23 Anvendelse af insulin-sensibiliserende midler til behandling af hypertension DK0514452T4 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US47809090A	1990-02-09	1990-02-09
PCT/US1991/000348 WO1991012003A1 (fr)	1990-02-09	1991-01-23	Utilisation d'agents de sensibilisation a l'insuline afin de traiter l'hypertension

Publications (2)

Publication Number	Publication Date
DK0514452T3 DK0514452T3 (da)	1993-11-29
DK0514452T4 true DK0514452T4 (da)	2000-09-18

Family

ID=23898474

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91904163T DK0514452T4 (da)	1990-02-09	1991-01-23	Anvendelse af insulin-sensibiliserende midler til behandling af hypertension

Country Status (12)

Country	Link
EP (1)	EP0514452B2 (fr)
JP (1)	JP3544659B2 (fr)
KR (1)	KR0170416B1 (fr)
AT (1)	ATE93138T1 (fr)
AU (1)	AU651571B2 (fr)
CA (1)	CA2071629C (fr)
DE (1)	DE69100282T3 (fr)
DK (1)	DK0514452T4 (fr)
ES (1)	ES2059121T5 (fr)
GR (1)	GR3034508T3 (fr)
HK (1)	HK153996A (fr)
WO (1)	WO1991012003A1 (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5175179A (en) *	1991-09-25	1992-12-29	Pfizer Inc.	Method for treating hypertension
US5874454A (en) *	1993-09-15	1999-02-23	Warner-Lambert Company	Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
US6046222A (en) *	1993-09-15	2000-04-04	Warner-Lambert Company	Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
US5478852C1 (en) *	1993-09-15	2001-03-13	Sankyo Co	Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus
US5594015A (en) *	1994-06-22	1997-01-14	Regents Of The University Of California	Thiazolidine derivatives for the treatment of psoriasis
US5925656A (en) *	1995-04-10	1999-07-20	Dr. Reddy's Research Foundation	Compounds having antidiabetic, hypolipidemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US6107323A (en) *	1996-04-05	2000-08-22	Takeda Chemical Industries, Ltd.	Pharmaceutical composition
JP2000511883A (ja) *	1996-04-19	2000-09-12	ノボノルディスクアクティーゼルスカブ	ホスホチロシン認識ユニットを有する分子のモジュレーター
US5958957A (en) *	1996-04-19	1999-09-28	Novo Nordisk A/S	Modulators of molecules with phosphotyrosine recognition units
US5919782A (en) *	1996-05-06	1999-07-06	Dr. Reddy's Research Foundation	Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
ZA973848B (en) *	1996-05-06	1997-12-02	Reddy Research Foundation	Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US5889025A (en) *	1996-05-06	1999-03-30	Reddy's Research Foundation	Antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5801173A (en) *	1996-05-06	1998-09-01	Dr. Reddy's Research Foundation	Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
CA2257284C (fr) *	1996-05-31	2005-10-04	Sankyo Company Limited	Remede pour maladies auto-immunes
HUP9903292A3 (en) *	1996-05-31	2000-08-28	Sankyo Co	Use of substances improving insulin resistance for production of remedies for autoimmune diseases
US6372750B2 (en)	1996-07-01	2002-04-16	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) *	1996-07-01	2006-09-05	Dr. Reddy's Laboratories, Limited	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US5885997A (en) *	1996-07-01	1999-03-23	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6114526A (en) *	1996-07-01	2000-09-05	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
BR9711098B1 (pt)	1996-07-01	2011-10-04		compostos heterocìclicos, processo para sua preparação e composições farmacêuticas contendo os mesmos e seu uso no tratamento de diabetes e doenças relacionadas.
US6011036A (en) *	1997-04-15	2000-01-04	Dr. Reddy's Research Foundation	Heterocyclic compounds having antidiabetic hypolipidemic antihypertensive properties process for their preparation and pharmaceutical compositions containing them
US6011031A (en) *	1997-05-30	2000-01-04	Dr. Reddy's Research Foundation	Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them
AU9762798A (en) *	1997-11-12	1999-05-31	Kyoto Pharmaceutical Industries, Ltd.	Novel thiazolidine compounds and medicinal utilization thereof
CZ20011655A3 (cs) *	1998-11-11	2002-06-12	Smithkline Beecham Plc	Léčivo pro léčení diabetes mellitus a stavů s ním spojených a farmaceutický prostředek obsahující beta -agonistu a daląí antidiabetické činidlo
PE20010580A1 (es) *	1999-09-03	2001-05-25	Takeda Chemical Industries Ltd	Composicion farmaceutica para tratar la diabetes
EP2638898A1 (fr)	2012-03-16	2013-09-18	Sanovel Ilac Sanayi ve Ticaret A.S.	Formulation de pioglitazone et metformine avec différents profils de libération
MA39929A (fr)	2014-11-27	2016-06-01	Arven Ilac Sanayi Ve Ticaret As	Comprimé multicouche comprenant de la metformine et du pioglitazone
TR201620309A2 (tr)	2016-12-30	2018-07-23	Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi	Metformi̇n hi̇droklori̇t ve pi̇ogli̇tazon hi̇droklori̇ti̇n farmasöti̇k bi̇leşi̇mleri̇

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3542927A (en) *	1965-08-10	1970-11-24	Pfizer	Reduction of blood sugar levels with aminomethylindoles
DE2965655D1 (en) *	1978-06-28	1983-07-21	Beecham Group Plc	Secondary amines, their preparation, pharmaceutical compositions containing them and their use
JPS5522636A (en) †	1978-08-04	1980-02-18	Takeda Chem Ind Ltd	Thiazoliding derivative
EP0052963B1 (fr) *	1980-11-20	1985-02-20	Beecham Group Plc	Amines secondaires
JPS6051189A (ja) *	1983-08-30	1985-03-22	Sankyo Co Ltd	チアゾリジン誘導体およびその製造法
DE3466387D1 (en) †	1983-11-04	1987-10-29	Beecham Group Plc	Tertiary amines
US4602044A (en) †	1983-12-19	1986-07-22	Eli Lilly And Company	β-phenethanolamine antiobesity agents
DE3419935A1 (de) *	1984-05-28	1985-11-28	Merck Patent Gmbh, 6100 Darmstadt	Verwendung von hydroxyindolderivaten bei der senkung des blutdrucks
AR240698A1 (es) *	1985-01-19	1990-09-28	Takeda Chemical Industries Ltd	Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales
GB8607312D0 (en) †	1986-03-25	1986-04-30	Ici Plc	Therapeutic agents
FR2611500B1 (fr) *	1987-03-06	1990-05-04	Lipha	Emploi de derives du biguanide dans la preparation de medicaments
IE940525L (en) *	1988-05-25	1989-11-25	Warner Lambert Co	Known and selected novel arylmethylenyl derivatives of¹thiazolidinones, imidazolidinones and oxazolidinones useful¹as antiallergy agents and antiinflammatory agents
GB8820389D0 (en) *	1988-08-26	1988-09-28	Beecham Group Plc	Novel compounds
US5143930A (en) *	1990-02-07	1992-09-01	Sankyo Company, Limited	Thiazolidine derivatives with anti-diabetic activity, their preparation and their use

1991
- 1991-01-23 DK DK91904163T patent/DK0514452T4/da active
- 1991-01-23 AU AU72416/91A patent/AU651571B2/en not_active Ceased
- 1991-01-23 WO PCT/US1991/000348 patent/WO1991012003A1/fr not_active Ceased
- 1991-01-23 ES ES91904163T patent/ES2059121T5/es not_active Expired - Lifetime
- 1991-01-23 JP JP50440791A patent/JP3544659B2/ja not_active Expired - Fee Related
- 1991-01-23 KR KR1019920701906A patent/KR0170416B1/ko not_active Expired - Fee Related
- 1991-01-23 AT AT91904163T patent/ATE93138T1/de not_active IP Right Cessation
- 1991-01-23 EP EP91904163A patent/EP0514452B2/fr not_active Expired - Lifetime
- 1991-01-23 DE DE69100282T patent/DE69100282T3/de not_active Expired - Fee Related
- 1991-01-23 CA CA002071629A patent/CA2071629C/fr not_active Expired - Fee Related
1996
- 1996-08-08 HK HK153996A patent/HK153996A/en not_active IP Right Cessation
2000
- 2000-09-28 GR GR20000402198T patent/GR3034508T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2059121T3 (es)	1994-11-01
HK153996A (en)	1996-08-16
DE69100282D1 (de)	1993-09-23
WO1991012003A1 (fr)	1991-08-22
DE69100282T2 (de)	1994-01-05
AU7241691A (en)	1991-09-03
KR0170416B1 (ko)	1999-02-18
CA2071629A1 (fr)	1991-08-10
GR3034508T3 (en)	2000-12-29
JP3544659B2 (ja)	2004-07-21
CA2071629C (fr)	1997-12-30
ATE93138T1 (de)	1993-09-15
DE69100282T3 (de)	2001-01-11
EP0514452B2 (fr)	2000-07-19
JPH05506430A (ja)	1993-09-22
DK0514452T3 (da)	1993-11-29
AU651571B2 (en)	1994-07-28
EP0514452A1 (fr)	1992-11-25
EP0514452B1 (fr)	1993-08-18
ES2059121T5 (es)	2000-12-01

Publication	Publication Date	Title
DK0514452T3 (da)	1993-11-29	Anvendelse af insulin-sensibiliserende midler til behandling af hypertension
EA200100572A1 (ru)	2002-02-28	Способ применения ингибитора циклооксигеназы-2 и одного или нескольких противоопухолевых лекарственных средств в качестве комбинированного способа лечебного воздействия при лечении неоплазии
LU91928I2 (fr)	2012-03-09	Ipilimumab et ses dérivés pharmaceutiquement acceptables (YERVOY®)
PT1333887E (pt)	2006-10-31	Metodo de tratamento de desordens musculares
SE9404196D0 (sv)	1994-12-02	New antithrombotic formulation
NO964527L (no)	1996-12-17	Blandinger omfattende DNA-ödeleggende midler og P53
NO970519L (no)	1997-04-07	Behandling av type II diabetes mellitus med amylinagonister
DE60215787D1 (de)	2006-12-14	Behandlung von typ ii diabetes mit dipeptidyl-peptidase-iv-hemmern
BR0116370A (pt)	2003-12-09	Composto, composição farmacêutica, uso de um composto, e, método de tratamento de uma doença ou condição mediada por hppar em um paciente.
DK0723444T3 (da)	1997-12-29	Levobupivacain, som er egnet til behandling af kronisk smerte
DK261490D0 (da)	1990-10-31	New pharmaceutical compound
EP0908186A3 (fr)	1999-04-21	Méthode de traitement de la douleur
DE60105025D1 (de)	2004-09-23	Pharmazeutische verbindungen zur behandlung von chronisch-obstruktiver bronchopneumonie
DK0934065T3 (da)	2006-10-09	Hidtil ukendte cruptophycinderivater som antieoplastiske midler
ATE174221T1 (de)	1998-12-15	Behandlung von pankreaskrankheit mit 15-keto- prostaglandin e-derivaten
DK1237562T3 (da)	2005-03-14	Fremgangsmåde til fremstilling af mikania-ekstrakter, som indeholder mikanolid og dihydromikanolid, og anvendelse i behandlingen af prolifererende sygdomme
EP0908180A3 (fr)	1999-04-21	Utilisation de dérivés phénylthiazolés ou phényloxazolés pour traiter la douleur
DK0468258T3 (da)	1996-02-26	Substituerede pyridooxaziner
TR199801801T2 (xx)	1998-12-21	Madde k�t�ye kullan�m�n�n tedavisi.
SE9500897D0 (sv)	1995-03-14	The pharmacological use of certain cystine derivatives
DE69635282D1 (de)	2006-02-23	Behandlung der exzessiven aggressivität mit olanzapine
SE9101341D0 (sv)	1991-05-03	New medicinal use
NO172120C (no)	1993-06-09	Analogifremgangsmaate for fremstilling av terapeutisk aktive isoxazoler
DK1304107T3 (da)	2005-08-22	Anvendelse af oxozolidinonderivater til behandling af psoriasis
TR200000957T2 (tr)	2000-08-21	Hiperglisemi tedavisinde tiazolidinedion kullanımı