DK0522092T3 - Iontophoretisk medikamentindgiftssystem med to-trins-indgiftsprofil - Google Patents

Iontophoretisk medikamentindgiftssystem med to-trins-indgiftsprofil

Info

Publication number
DK0522092T3
DK0522092T3 DK91911198.9T DK91911198T DK0522092T3 DK 0522092 T3 DK0522092 T3 DK 0522092T3 DK 91911198 T DK91911198 T DK 91911198T DK 0522092 T3 DK0522092 T3 DK 0522092T3
Authority
DK
Denmark
Prior art keywords
level
iontophoretic
current
stage
agent
Prior art date
Application number
DK91911198.9T
Other languages
English (en)
Inventor
Gary A Lattin
Larry A Mcnichols
Paul D Sorenson
John D Bradzinski
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27054046&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0522092(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DK0522092T3 publication Critical patent/DK0522092T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DK91911198.9T 1990-03-30 1991-03-22 Iontophoretisk medikamentindgiftssystem med to-trins-indgiftsprofil DK0522092T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50217690A 1990-03-30 1990-03-30
US07/671,306 US5207752A (en) 1990-03-30 1991-03-21 Iontophoretic drug delivery system with two-stage delivery profile

Publications (1)

Publication Number Publication Date
DK0522092T3 true DK0522092T3 (da) 1995-03-13

Family

ID=27054046

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91911198.9T DK0522092T3 (da) 1990-03-30 1991-03-22 Iontophoretisk medikamentindgiftssystem med to-trins-indgiftsprofil

Country Status (14)

Country Link
US (1) US5207752A (da)
EP (1) EP0522092B1 (da)
JP (1) JP3181289B2 (da)
KR (1) KR0169084B1 (da)
AT (1) ATE114118T1 (da)
AU (1) AU638581B2 (da)
CA (1) CA2079316C (da)
DE (1) DE69105202T2 (da)
DK (1) DK0522092T3 (da)
ES (1) ES2067939T3 (da)
FI (1) FI110066B (da)
GR (1) GR3015116T3 (da)
NO (1) NO308025B1 (da)
WO (1) WO1991015258A1 (da)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5207752A (en) 1990-03-30 1993-05-04 Alza Corporation Iontophoretic drug delivery system with two-stage delivery profile
MX9206990A (es) 1991-12-03 1993-06-01 Alza Corp Dispositivo iontoforetico de surtido y suministro de energia para el mismo.
US5505715A (en) * 1994-02-25 1996-04-09 Bristol-Myers Squibb Company Iontophoretic transdermal delivery of deoxyspergualin compounds
US7027859B1 (en) 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
US5697896A (en) * 1994-12-08 1997-12-16 Alza Corporation Electrotransport delivery device
US5700481A (en) * 1995-03-17 1997-12-23 Takeda Chemical Industries, Ltd. Transdermal drug delivery process
US6032073A (en) * 1995-04-07 2000-02-29 Novartis Ag Iontophoretic transdermal system for the administration of at least two substances
IE960312A1 (en) * 1995-06-02 1996-12-11 Alza Corp An electrotransport delivery device with voltage boosting¹circuit
US5983130A (en) * 1995-06-07 1999-11-09 Alza Corporation Electrotransport agent delivery method and apparatus
AU710793B2 (en) * 1995-06-07 1999-09-30 Alza Corporation Electrotransport agent delivery method and apparatus
WO1997014473A1 (en) * 1995-10-18 1997-04-24 Novartis Ag Thermopile powered transdermal drug delivery device
US6718201B1 (en) * 1996-06-07 2004-04-06 Alza Corporation Electrotransport agent delivery method and apparatus
AU3404197A (en) * 1996-06-19 1998-01-07 Becton Dickinson & Company Iontophoretic delivery of cell adhesion inhibitors
US5857994A (en) * 1996-10-01 1999-01-12 Becton, Dickinson And Company Awakenable iontophoretic/delivery device for reducing electrical sensation upon application thereof
FR2766093B1 (fr) * 1997-07-15 1999-09-03 Lhd Lab Hygiene Dietetique Procede de commande d'un dispositif d'administration transdermique de medicament sous champ electrique
WO1999030773A1 (en) 1997-12-16 1999-06-24 Alza Corporation Regulator with artificial load to maintain regulated delivery
JP4362012B2 (ja) 1997-12-17 2009-11-11 アルザ・コーポレーション 電流がプログラム調整されたイオン導入法
ATE197408T1 (de) 1998-01-30 2000-11-11 Novo Nordisk As Eine injektionsspritze
BR0008123A (pt) 1999-02-10 2001-11-13 Gmp Drug Delivery Inc Dispositivo baseado em emplastro para aumentar aliberação local de um agente de tratamento paradentro de tecidos alvo, e, processo de liberaçãode um agente de tratamento para dentro detecidos alvo de uma vesìcula corporal
US6471675B1 (en) 1999-04-30 2002-10-29 Medtronic, Inc. Passive flow control devices for implantable pumps
TW453884B (en) 1999-09-16 2001-09-11 Novo Nordisk As Dose setting limiter
US6663602B2 (en) 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
IL155730A0 (en) * 2000-11-03 2003-11-23 Biomedicines Inc Method for short-term and long-term drug dosimetry
CA2466228A1 (en) * 2001-11-09 2003-08-07 Biomedicines, Inc. Method for treating diseases with omega interferon
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
GB0304822D0 (en) * 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
US9205197B2 (en) * 2003-03-03 2015-12-08 Sanofi-Aventis Deutschland Gmbh Drug delivery device dose setting mechanism
GB0308267D0 (en) * 2003-04-10 2003-05-14 Dca Design Int Ltd Improvements in and relating to a pen-type injector
US7220778B2 (en) * 2003-04-15 2007-05-22 The General Hospital Corporation Methods and devices for epithelial protection during photodynamic therapy
US7596407B2 (en) * 2004-03-26 2009-09-29 Solvay Pharmaceuticals, B.V. Transdermal iontophoretic delivery of piperazinyl-2(3H)-benzoxazolone compounds
EP1595542A1 (en) * 2004-03-26 2005-11-16 Solvay Pharmaceuticals B.V. Transdermal iontophoretic delivery of piperazinyl-2(3H)-benzoxazolone compounds
EP1804865B1 (en) 2004-10-21 2009-09-30 Novo Nordisk A/S Dial-down mechanism for wind-up pen
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
EP1855744A1 (en) * 2005-02-28 2007-11-21 Novo Nordisk A/S A dose setting mechanism for an injection device
US7856263B2 (en) 2005-04-22 2010-12-21 Travanti Pharma Inc. Transdermal systems for the delivery of therapeutic agents including granisetron using iontophoresis
US20090043264A1 (en) * 2005-04-24 2009-02-12 Novo Nordisk A/S Injection Device
BRPI0616487A2 (pt) * 2005-09-30 2011-06-21 Tti Ellebeau Inc aparato e método de iontoforese para liberação sistêmica de agentes ativos
WO2007046103A2 (en) * 2005-10-19 2007-04-26 Perf-Action Technologies Ltd. System for iontophoretic transdermal delivery of polymeric agents and methods of use thereof
US8361036B2 (en) 2006-03-10 2013-01-29 Novo Nordisk A/S Injection device having a gearing arrangement
WO2007104636A1 (en) 2006-03-10 2007-09-20 Novo Nordisk A/S An injection device and a method of changing a cartridge in the device
EA023147B1 (ru) * 2006-04-13 2016-04-29 Тева Фармасьютикалс Интернешнл Гмбх Трансдермальный пластырь для лечения мигрени
AU2012261753B2 (en) * 2006-04-13 2015-03-05 Teva Pharmaceuticals International Gmbh Transdermal methods and systems for the delivery of anti-migraine compounds
ATE458517T1 (de) 2006-05-16 2010-03-15 Novo Nordisk As Getriebemechanismus für ein injektionsgerät
WO2007132526A1 (ja) * 2006-05-16 2007-11-22 Rorze Corporation シャトル型搬送装置、マイクロプレート供給回収装置、マイクロプレート用ピックアップ装置、マイクロプレート用カセット、及びマイクロプレート用収納棚
BRPI0712028A2 (pt) 2006-05-18 2011-12-20 Novo Nordisk As dispositivo de injenção com um meio de travamento de modo
KR101106510B1 (ko) 2006-05-30 2012-01-20 인타르시아 세라퓨틱스 인코포레이티드 투피스, 내부채널 삼투압 전달 시스템 유동 조절기
EP2359808B1 (en) 2006-08-09 2013-05-22 Intarcia Therapeutics, Inc Osmotic delivery systems and piston assemblies
US8728059B2 (en) * 2006-09-29 2014-05-20 Covidien Lp System and method for assuring validity of monitoring parameter in combination with a therapeutic device
WO2008095762A1 (en) 2007-02-05 2008-08-14 Novo Nordisk A/S Injection button
RU2468829C2 (ru) 2007-03-23 2012-12-10 Ново Нордиск А/С Инъекционное устройство, содержащее стопорную гайку
WO2008133908A2 (en) 2007-04-23 2008-11-06 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
ES2454974T3 (es) * 2007-06-27 2014-04-14 The General Hospital Corporation Aparato para la inhibición óptica de la terapia fotodinámica
US20090043244A1 (en) * 2007-08-08 2009-02-12 Inan Omer T Electrotransport Drug Delivery Device Adaptable to Skin Resistance Change
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
US20090259176A1 (en) * 2008-04-09 2009-10-15 Los Gatos Research, Inc. Transdermal patch system
US20090312689A1 (en) * 2008-06-05 2009-12-17 Alza Corporation Adjustable Current Electrotransport Fentanyl Delivery Device
US8366600B2 (en) * 2008-06-19 2013-02-05 Nupathe Inc. Polyamine enhanced formulations for triptan compound iontophoresis
US8155737B2 (en) * 2008-06-19 2012-04-10 Nupathe, Inc. Pharmacokinetics of iontophoretic sumatriptan administration
WO2010078313A1 (en) * 2008-12-30 2010-07-08 Nupathe, Inc. Electronic control of drug delivery system
US9008765B2 (en) 2009-02-12 2015-04-14 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents for the control of addictive cravings
US8961492B2 (en) 2009-02-12 2015-02-24 Incube Labs, Llc System and method for controlling the iontophoretic delivery of therapeutic agents based on user inhalation
US8190252B2 (en) 2009-02-12 2012-05-29 Incube Labs, Llc Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes
US8903485B2 (en) 2009-08-06 2014-12-02 Incube Labs, Llc Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes
CN105796533A (zh) * 2009-08-10 2016-07-27 泰华制药国际有限公司 用离子电渗疗法治疗恶心和偏头痛的方法
RU2547990C2 (ru) 2009-09-28 2015-04-10 Интарсия Терапьютикс, Инк. Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства
US20110087153A1 (en) * 2009-10-13 2011-04-14 Angelov Angel S Transdermal Methods And Systems For The Delivery Of Rizatriptan
US8685038B2 (en) 2009-12-07 2014-04-01 Incube Labs, Llc Iontophoretic apparatus and method for marking of the skin
WO2011100376A2 (en) 2010-02-10 2011-08-18 Incube Labs, Llc Methods and architecture for power optimization of iontophoretic transdermal drug delivery
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
EP3626304A1 (en) 2011-03-24 2020-03-25 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents
US8428708B1 (en) * 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
CA2861706A1 (en) 2011-12-29 2013-07-04 Novo Nordisk A/S Dial-up/dial-down mechanism for wind-up pen
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
RU2730996C2 (ru) 2015-06-03 2020-08-26 Интарсия Терапьютикс, Инк. Системы установки и извлечения имплантата
KR102574993B1 (ko) 2016-05-16 2023-09-06 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
JP7286542B2 (ja) 2017-01-03 2023-06-05 インターシア セラピューティクス，インコーポレイティド Ｇｌｐ－１受容体アゴニストの持続的投与及び薬物の同時投与を含む方法
KR102665710B1 (ko) 2017-08-24 2024-05-14 노보 노르디스크 에이/에스 Glp-1 조성물 및 그 용도
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
JP7761567B2 (ja) 2020-02-18 2025-10-28 ノヴォ ノルディスク アー／エス 医薬製剤

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3163166A (en) * 1961-04-28 1964-12-29 Colgate Palmolive Co Iontophoresis apparatus
US3618601A (en) * 1969-10-16 1971-11-09 Thatcher W Richardson Iontophoresis unit
US3677268A (en) * 1969-11-28 1972-07-18 Sherwood Medical Ind Inc Iontophoresis electrode
US3794910A (en) * 1971-07-26 1974-02-26 Sherwood Medical Ind Inc Iontophoresis and conductivity analysis circuit
DE2339648C3 (de) * 1973-08-04 1979-09-13 Trebbin, Peter, 8833 Eichstaett Anästhesiegerät zur Behandlung der Zähne
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4211222A (en) * 1976-08-25 1980-07-08 Robert Tapper Iontophoretic burn-protection method
JPS5347192A (en) * 1976-10-13 1978-04-27 Matsushita Electric Industrial Co Ltd Device for introducing fluorine ion to tooth
US4325367A (en) * 1977-06-13 1982-04-20 Robert Tapper Iontophoretic treatment apparatus
US4177817A (en) * 1978-02-01 1979-12-11 C. R. Bard, Inc. Dual terminal transcutaneous electrode
US4215696A (en) * 1978-03-20 1980-08-05 Graphic Controls Corporation Biomedical electrode with pressurized skin contact
US4209020A (en) * 1978-09-19 1980-06-24 Nielsen R Frederick Electrode assembly
US4340047A (en) * 1978-10-18 1982-07-20 Robert Tapper Iontophoretic treatment apparatus
US4301794A (en) * 1978-10-18 1981-11-24 Robert Tapper Method for iontophoretic treatment
US4292968A (en) * 1979-11-26 1981-10-06 Sybron Corporation Electric supply for ion therapy
AU546785B2 (en) * 1980-07-23 1985-09-19 Commonwealth Of Australia, The Open-loop controlled infusion of diabetics
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
US4450844A (en) * 1981-11-23 1984-05-29 Hill Top Research, Inc. Patch system for use on the skin
EP0140980A4 (en) * 1983-04-15 1987-09-15 Jack Kenneth Ibbott APPARATUS USING A FLAT BATTERY.
US4622031A (en) * 1983-08-18 1986-11-11 Drug Delivery Systems Inc. Indicator for electrophoretic transcutaneous drug delivery device
US4731926A (en) * 1985-02-19 1988-03-22 Drug Delivery Systems Inc. Method of manufacturing disposable and/or replenishable transdermal drug applicators
US4557723A (en) * 1983-08-18 1985-12-10 Drug Delivery Systems Inc. Applicator for the non-invasive transcutaneous delivery of medicament
US4640689A (en) * 1983-08-18 1987-02-03 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
US4708716A (en) * 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
US4808152A (en) * 1983-08-18 1989-02-28 Drug Delivery Systems Inc. System and method for controlling rate of electrokinetic delivery of a drug
US4883457A (en) * 1983-08-18 1989-11-28 Drug Delivery Systems Inc. Disposable and/or replenishable transdermal drug applicators and methods of manufacturing same
US4851229A (en) * 1983-12-01 1989-07-25 Alza Corporation Composition comprising a therapeutic agent and a modulating agent
ATE50915T1 (de) * 1985-06-10 1990-03-15 Drug Delivery Systems Inc Anlage und verfahren zur steuerung der elektrokinetischen lieferungsgeschwindigkeit einer arznei.
US4698062A (en) * 1985-10-30 1987-10-06 Alza Corporation Medical device for pulsatile transdermal delivery of biologically active agents
US4725263A (en) * 1986-07-31 1988-02-16 Medtronic, Inc. Programmable constant current source transdermal drug delivery system
US4822334A (en) * 1986-12-04 1989-04-18 Robert Tapper Electrical dosimetry control system
US4731049A (en) * 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery
EP0313638A4 (en) * 1987-05-15 1989-06-14 Martin H Newman IONTOPHORESIS INOPHORESIS DRUG ADMINISTRATION SYSTEM.
US4865582A (en) * 1987-06-05 1989-09-12 Drug Delivery Systems Inc. Disposable transdermal drug applicators
US5207752A (en) 1990-03-30 1993-05-04 Alza Corporation Iontophoretic drug delivery system with two-stage delivery profile

Also Published As

Publication number Publication date
DE69105202T2 (de) 1995-03-23
NO923769L (no) 1992-11-30
ES2067939T3 (es) 1995-04-01
GR3015116T3 (en) 1995-05-31
JPH05505964A (ja) 1993-09-02
EP0522092A1 (en) 1993-01-13
JP3181289B2 (ja) 2001-07-03
NO308025B1 (no) 2000-07-10
DE69105202D1 (de) 1994-12-22
KR930700181A (ko) 1993-03-13
KR0169084B1 (ko) 1999-01-15
AU638581B2 (en) 1993-07-01
NO923769D0 (no) 1992-09-28
FI924352L (fi) 1992-09-28
FI110066B (fi) 2002-11-29
WO1991015258A1 (en) 1991-10-17
AU7991591A (en) 1991-10-30
EP0522092B1 (en) 1994-11-17
FI924352A0 (fi) 1992-09-28
CA2079316C (en) 2002-01-01
ATE114118T1 (de) 1994-12-15
CA2079316A1 (en) 1991-10-01
US5207752A (en) 1993-05-04

Similar Documents

Publication Publication Date Title
DK0522092T3 (da) Iontophoretisk medikamentindgiftssystem med to-trins-indgiftsprofil
NO306377B1 (no) Doseform for avgivelse av et medikament
IT1261849B (it) Dispositivo medico per la somministrazione di principi attivi o farmaci a bassissimo dosaggio, in particolare di farmaci omeopatici.
PL287844A1 (en) Method of obtaining an oraly administered composite medicine for treating interstinal inflamatory diseases
ATE234602T1 (de) Verabreichungsform zur abgabe von steigenden wirkstoffdosen
ATE515265T1 (de) Vitamin d und dessen analoge zur behandlung vom tumoren und anderen hyperproliferativen erkrankungen
GEP20002146B (en) Therapeutic Peptide Derivatives
SE9703191D0 (sv) Medicament for improvement of duration of muscle function or treatment of muscle disorders or diseases
CO4290346A1 (es) Formas de dosificacion de liberacion controlada de azitromicina
DE69735848D1 (de) Dosisform mit ansteigender dosisfreisetzung
DK0617623T3 (da) Acetylsalicylsyreholdigt transdermalt indgivelsessystem til antithrombotisk behandling
AR025449A1 (es) Soluciones farmaceuticas de levosimendan
PT904067E (pt) Dextrometorfan como agente antitussico administrado transdermicamente
KR870700373A (ko) 동전학적 의약투여 속도를 제어하는 시스텝 및 방법
ES2043744T3 (es) Sistema de suministro transdermico de procaterol.
DK0559145T3 (da) Lægemiddel til truende abort
TWI263502B (en) Pharmaceutical preparation for treating ischemic disease of heart or limbs
SE9000207D0 (sv) Laekemedel samt anvaendningen av detsamma
ES2103811T3 (es) Terapia antiviral.
Fu et al. A clinical comparative study on effects of intracavernous injection of sodium nitroprusside and papaverine/phentolamine in erectile dysfunction patients
SE9101341D0 (sv) New medicinal use
SE9904424D0 (sv) Use of interleukin-6 in combination with leptin in treatment of obesity
RU2000110676A (ru) Способ консервативного лечения стриктур уретры
DK0538335T3 (da) Doseringsform til administration af et lægemiddel til at bevirke circadisk terapi
RU96104613A (ru) Способ лечения больных эндокринной офтальмопатией