DK0595546T3 - Benzylidenderivater - Google Patents
BenzylidenderivaterInfo
- Publication number
- DK0595546T3 DK0595546T3 DK93308369.3T DK93308369T DK0595546T3 DK 0595546 T3 DK0595546 T3 DK 0595546T3 DK 93308369 T DK93308369 T DK 93308369T DK 0595546 T3 DK0595546 T3 DK 0595546T3
- Authority
- DK
- Denmark
- Prior art keywords
- hydrogen
- substituted
- lower alkyl
- lower alkoxy
- formula
- Prior art date
Links
- 125000000649 benzylidene group Chemical group [H]C(=[*])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000002102 aryl alkyloxo group Chemical group 0.000 abstract 1
- 125000005129 aryl carbonyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000005114 heteroarylalkoxy group Chemical group 0.000 abstract 1
- ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical group O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
- C07D291/02—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms not condensed with other rings
- C07D291/06—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
- C07D333/48—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Liquid Crystal Substances (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28997292 | 1992-10-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0595546T3 true DK0595546T3 (da) | 1996-04-15 |
Family
ID=17750115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93308369.3T DK0595546T3 (da) | 1992-10-28 | 1993-10-20 | Benzylidenderivater |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5418230A (da) |
| EP (1) | EP0595546B1 (da) |
| KR (1) | KR100281490B1 (da) |
| CN (1) | CN1035614C (da) |
| AT (1) | ATE135697T1 (da) |
| AU (1) | AU675078B2 (da) |
| CA (1) | CA2109498A1 (da) |
| DE (1) | DE69301894T2 (da) |
| DK (1) | DK0595546T3 (da) |
| ES (1) | ES2089736T3 (da) |
| GR (1) | GR3019395T3 (da) |
| HU (1) | HU215924B (da) |
| NO (1) | NO303828B1 (da) |
| TW (1) | TW378207B (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3507124B2 (ja) * | 1993-05-26 | 2004-03-15 | 塩野義製薬株式会社 | ベンジリデン誘導体の製造法 |
| DE19700061A1 (de) * | 1997-01-03 | 1998-07-09 | Hoechst Schering Agrevo Gmbh | Verfahren zur Herstellung von cyclischen N-Aminosulfonamiden |
| KR20010031319A (ko) | 1997-10-24 | 2001-04-16 | 요시히코 시오노 | 항류마티스제 |
| US6649645B1 (en) | 1998-12-23 | 2003-11-18 | Pharmacia Corporation | Combination therapy of radiation and a COX-2 inhibitor for treatment of neoplasia |
| US6632452B1 (en) | 1999-01-21 | 2003-10-14 | Shionogi & Co., Ltd. | Medicinal compositions retarded in the discoloration of phenolic hydroxyl compounds |
| WO2002007721A2 (en) | 2000-07-20 | 2002-01-31 | Lauras As | Use of cox-2 inhibitors for preventing immunodeficiency |
| WO2002080974A1 (en) * | 2001-04-04 | 2002-10-17 | Sankyo Company, Limited | Novel medicinal use of cytokine production inhibitor |
| AR038957A1 (es) | 2001-08-15 | 2005-02-02 | Pharmacia Corp | Terapia de combinacion para el tratamiento del cancer |
| ES2341240T3 (es) | 2002-12-13 | 2010-06-17 | Warner-Lambert Company Llc | Ligando alfa-2-delta para tratar los sintomas del tracto urinario inferior. |
| EP1708718A1 (en) | 2004-01-22 | 2006-10-11 | Pfizer Limited | Triazole derivatives which inhibit vasopressin antagonistic activity |
| BRPI0708804B8 (pt) | 2006-03-17 | 2021-05-25 | Cardioxyl Pharmaceuticals Inc | compostos derivados de n-hidroxilsulfonamida como doadores de nitroxil, composição farmacêutica e kit |
| UA94979C2 (uk) | 2006-12-22 | 2011-06-25 | Рекордати Айеленд Лимитед | КОМБІНОВАНА ТЕРАПІЯ ПОРУШЕНЬ НИЖНІХ СЕЧОВИВІДНИХ ШЛЯХІВ ЛІГАНДАМИ α2δ І НПЗП |
| GB0903493D0 (en) | 2009-02-27 | 2009-04-08 | Vantia Ltd | New compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH066571B2 (ja) * | 1985-05-09 | 1994-01-26 | エーザイ株式会社 | ２−ピロリドン誘導体 |
| PT83152B (pt) * | 1985-08-09 | 1989-03-30 | Lilly Co Eli | Processo para a preparacao de compostos di-t-butilfenoicos |
| DE68907095T2 (de) * | 1988-03-21 | 1994-01-05 | Boehringer Ingelheim Pharma | Verbindungen zur Verhinderung der Biosynthese von der Lipoxygenase abgeleiteten Metaboliten der Arachidonsäure. |
| NZ231534A (en) * | 1988-11-29 | 1992-02-25 | Warner Lambert Co | 3,5-di-t-butyl-4-hydroxyphenyl-triazoles, oxadiazoles and thiadiazoles; anti-inflammatory compositions |
| US4895862A (en) * | 1989-04-21 | 1990-01-23 | American Home Products Corp. | Novel benzyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents |
| IL96654A (en) * | 1989-12-21 | 1995-06-29 | Lilly Co Eli | Hydroxybenzyl substituted sulfur containing heterocyclic derivatives their preparation and pharmaceutical compositions containing them |
| EP0525197B1 (en) * | 1991-01-21 | 1997-08-27 | Shionogi Seiyaku Kabushiki Kaisha | 3-benzylidene-1-carbamoyl-2-pyrrolidone analogs |
-
1993
- 1993-10-20 AT AT93308369T patent/ATE135697T1/de not_active IP Right Cessation
- 1993-10-20 DK DK93308369.3T patent/DK0595546T3/da active
- 1993-10-20 AU AU49107/93A patent/AU675078B2/en not_active Ceased
- 1993-10-20 EP EP93308369A patent/EP0595546B1/en not_active Expired - Lifetime
- 1993-10-20 ES ES93308369T patent/ES2089736T3/es not_active Expired - Lifetime
- 1993-10-20 DE DE69301894T patent/DE69301894T2/de not_active Expired - Fee Related
- 1993-10-22 TW TW082108811A patent/TW378207B/zh not_active IP Right Cessation
- 1993-10-27 NO NO933870A patent/NO303828B1/no not_active IP Right Cessation
- 1993-10-27 HU HU9303053A patent/HU215924B/hu not_active IP Right Cessation
- 1993-10-27 KR KR1019930022532A patent/KR100281490B1/ko not_active Expired - Fee Related
- 1993-10-28 CA CA002109498A patent/CA2109498A1/en not_active Abandoned
- 1993-10-28 CN CN93120706A patent/CN1035614C/zh not_active Expired - Fee Related
- 1993-10-28 US US08/142,146 patent/US5418230A/en not_active Expired - Fee Related
-
1996
- 1996-03-21 GR GR960400642T patent/GR3019395T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2089736T3 (es) | 1996-10-01 |
| NO933870L (no) | 1994-04-29 |
| CN1092414A (zh) | 1994-09-21 |
| GR3019395T3 (en) | 1996-06-30 |
| DE69301894T2 (de) | 1996-11-07 |
| KR100281490B1 (ko) | 2001-02-15 |
| HU215924B (hu) | 1999-03-29 |
| US5418230A (en) | 1995-05-23 |
| EP0595546A1 (en) | 1994-05-04 |
| NO303828B1 (no) | 1998-09-07 |
| CN1035614C (zh) | 1997-08-13 |
| AU675078B2 (en) | 1997-01-23 |
| EP0595546B1 (en) | 1996-03-20 |
| TW378207B (en) | 2000-01-01 |
| HU9303053D0 (en) | 1994-01-28 |
| DE69301894D1 (de) | 1996-04-25 |
| KR940009163A (ko) | 1994-05-20 |
| AU4910793A (en) | 1994-05-12 |
| HUT70530A (en) | 1995-10-30 |
| NO933870D0 (no) | 1993-10-27 |
| ATE135697T1 (de) | 1996-04-15 |
| CA2109498A1 (en) | 1994-04-29 |
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