DK0595868T3 - Fremgangsmåde til fremstilling af (S)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)-1-hydroxypropyl]-brombenzen - Google Patents

Fremgangsmåde til fremstilling af (S)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)-1-hydroxypropyl]-brombenzen

Info

Publication number
DK0595868T3
DK0595868T3 DK92915192T DK92915192T DK0595868T3 DK 0595868 T3 DK0595868 T3 DK 0595868T3 DK 92915192 T DK92915192 T DK 92915192T DK 92915192 T DK92915192 T DK 92915192T DK 0595868 T3 DK0595868 T3 DK 0595868T3
Authority
DK
Denmark
Prior art keywords
preparation
bromobenzene
oxazolyl
hydroxypropyl
phenyl
Prior art date
Application number
DK92915192T
Other languages
English (en)
Inventor
George J Quallich
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0595868T3 publication Critical patent/DK0595868T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK92915192T 1991-07-22 1992-07-01 Fremgangsmåde til fremstilling af (S)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)-1-hydroxypropyl]-brombenzen DK0595868T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73356491A 1991-07-22 1991-07-22
PCT/US1992/005433 WO1993002060A1 (en) 1991-07-22 1992-07-01 Process for the preparation of intermediates in the synthesis of chiral thiazolidine-2,4-dione derivatives

Publications (1)

Publication Number Publication Date
DK0595868T3 true DK0595868T3 (da) 1999-08-09

Family

ID=24948157

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92915192T DK0595868T3 (da) 1991-07-22 1992-07-01 Fremgangsmåde til fremstilling af (S)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)-1-hydroxypropyl]-brombenzen

Country Status (21)

Country Link
US (1) US5512689A (da)
EP (1) EP0595868B1 (da)
JP (1) JP2671962B2 (da)
AT (1) ATE173728T1 (da)
AU (1) AU660701B2 (da)
CA (1) CA2111445C (da)
DE (1) DE69227689T2 (da)
DK (1) DK0595868T3 (da)
ES (1) ES2123562T3 (da)
FI (1) FI940306A7 (da)
HU (1) HUT70412A (da)
IE (1) IE922359A1 (da)
IL (1) IL102574A (da)
MX (1) MX9204278A (da)
MY (1) MY131277A (da)
NO (1) NO940227L (da)
NZ (1) NZ243651A (da)
PT (1) PT100710B (da)
TW (1) TW199891B (da)
WO (1) WO1993002060A1 (da)
ZA (1) ZA925469B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU660187B2 (en) * 1991-07-22 1995-06-15 Pfizer Inc. Chiral intermediates for the preparation of antidiabetics thiazoles
FR2699172B1 (fr) * 1992-12-11 1995-01-20 Adir Nouveaux dérivés de 4-méthyl-1,3-oxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
TW416958B (en) * 1993-05-14 2001-01-01 Pfizer Enantioselective oxazaborolidine catalysts
JP2003508391A (ja) 1999-08-31 2003-03-04 マキシア・ファーマシューティカルズ・インコーポレイテッド ベンジリデン−チアゾリジンジオン類およびアナログ類ならびに糖尿病の治療におけるその使用
AU2002252227A1 (en) 2001-03-07 2002-09-24 Maxia Pharmaceuticals, Inc. Heterocyclic derivatives for the treatment of cancer and other proliferative diseases
JP2004523571A (ja) * 2001-03-08 2004-08-05 マキシア・ファーマシューティカルズ・インコーポレイテッド Ｒｘｒ活性化分子
CA2340824A1 (en) * 2001-03-14 2002-09-14 Ibm Canada Limited-Ibm Canada Limitee Method and system for application behavior analysis
WO2003016267A1 (en) * 2001-08-17 2003-02-27 Incyte San Diego Incorporated Oxime derivatives for the treatment of dyslipidemia and hypercholesteremia
JP2005513026A (ja) * 2001-11-15 2005-05-12 インサイト サン ディエゴ インコーポレイテッド 高コレステロール血症、異脂肪血症および他の代謝障害；癌、および他の疾患を治療するｎ−置換複素環
US7196108B2 (en) * 2002-03-08 2007-03-27 Incyte San Diego Inc. Bicyclic heterocycles for the treatment of diabetes and other diseases
US7102000B2 (en) * 2002-03-08 2006-09-05 Incyte San Diego Inc. Heterocyclic amide derivatives for the treatment of diabetes and other diseases
US20050014767A1 (en) * 2003-01-29 2005-01-20 Magnus Pfahl Benzoxazole, benzothiazole, and benzimidazole derivatives for the treatment of cancer and other diseases
US20050038098A1 (en) * 2003-04-18 2005-02-17 Catherine Tachdjian Substituted dihydronaphthalene and isochroman compounds for the treatment of metabolic disorders, cancer and other diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4943635A (en) * 1987-08-27 1990-07-24 President & Fellows Of Harvard College Enantioselective reduction of ketones
US5036079A (en) * 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
TW222626B (da) * 1991-07-22 1994-04-21 Pfizer

Also Published As

Publication number Publication date
AU2306292A (en) 1993-02-23
IL102574A (en) 1996-07-23
CA2111445C (en) 1997-02-18
EP0595868B1 (en) 1998-11-25
DE69227689D1 (de) 1999-01-07
NZ243651A (en) 1994-01-26
NO940227D0 (no) 1994-01-21
MX9204278A (es) 1994-03-31
NO940227L (no) 1994-01-21
ZA925469B (en) 1994-01-21
CA2111445A1 (en) 1993-02-04
MY131277A (en) 2007-07-31
ATE173728T1 (de) 1998-12-15
FI940306L (fi) 1994-01-21
EP0595868A1 (en) 1994-05-11
FI940306A0 (fi) 1994-01-21
TW199891B (da) 1993-02-11
IL102574A0 (en) 1993-01-14
DE69227689T2 (de) 1999-04-22
FI940306A7 (fi) 1994-01-21
HU9400188D0 (en) 1994-05-30
JPH07502017A (ja) 1995-03-02
US5512689A (en) 1996-04-30
JP2671962B2 (ja) 1997-11-05
ES2123562T3 (es) 1999-01-16
PT100710B (pt) 1999-07-30
HUT70412A (en) 1995-10-30
IE922359A1 (en) 1993-01-27
AU660701B2 (en) 1995-07-06
PT100710A (pt) 1993-09-30
WO1993002060A1 (en) 1993-02-04

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