DK0606921T3 - Fremgangsmåde til isolering af Haemophilus influenzae protein E - Google Patents
Fremgangsmåde til isolering af Haemophilus influenzae protein EInfo
- Publication number
- DK0606921T3 DK0606921T3 DK94100492T DK94100492T DK0606921T3 DK 0606921 T3 DK0606921 T3 DK 0606921T3 DK 94100492 T DK94100492 T DK 94100492T DK 94100492 T DK94100492 T DK 94100492T DK 0606921 T3 DK0606921 T3 DK 0606921T3
- Authority
- DK
- Denmark
- Prior art keywords
- isolating
- extracting
- haemophilus influenzae
- protein
- influenzae protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Gram-negative bacteria
- C07K16/1242—Gram-negative bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32097189A | 1989-03-09 | 1989-03-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0606921T3 true DK0606921T3 (da) | 2000-09-04 |
Family
ID=23248627
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90905112.0T DK0462210T3 (da) | 1989-03-09 | 1990-03-09 | Vacciner mod ikke-typebestemmelige Haemophilus influenzae |
| DK94100492T DK0606921T3 (da) | 1989-03-09 | 1990-03-09 | Fremgangsmåde til isolering af Haemophilus influenzae protein E |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90905112.0T DK0462210T3 (da) | 1989-03-09 | 1990-03-09 | Vacciner mod ikke-typebestemmelige Haemophilus influenzae |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US5601831A (da) |
| EP (2) | EP0462210B1 (da) |
| JP (1) | JP2955014B2 (da) |
| KR (1) | KR100188323B1 (da) |
| AT (2) | ATE195076T1 (da) |
| AU (1) | AU648251B2 (da) |
| CA (1) | CA2047681C (da) |
| DE (2) | DE69033600T2 (da) |
| DK (2) | DK0462210T3 (da) |
| ES (2) | ES2063965T3 (da) |
| FI (1) | FI914241A0 (da) |
| NO (1) | NO913518L (da) |
| WO (1) | WO1990010458A1 (da) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1340888C (en) * | 1988-09-01 | 2000-02-01 | Algis Anilionis | Vaccines and diagnostic assays for haemophilus influenzae |
| WO1993008290A1 (en) * | 1991-10-16 | 1993-04-29 | University Of Saskatchewan | Enhanced immunogenicity using leukotoxin chimeras |
| US6797272B1 (en) | 1991-10-16 | 2004-09-28 | University Of Saskatchewan | Enhanced immunogenicity using leukotoxin chimeras |
| US5422110A (en) * | 1991-10-16 | 1995-06-06 | University Of Saskatchewan | Enhanced immunogenicity using leukotoxin chimeras |
| DK0624376T3 (da) * | 1993-05-13 | 2000-07-24 | American Cyanamid Co | Fremstilling og anvendelse af LOS-udtømte ydre membranproteiner af gram-negative cocci |
| US5681570A (en) * | 1995-01-12 | 1997-10-28 | Connaught Laboratories Limited | Immunogenic conjugate molecules |
| US20020032316A1 (en) * | 1995-03-31 | 2002-03-14 | Cantab Pharmaceuticals Research Limited | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same |
| WO1996032963A1 (en) * | 1995-04-17 | 1996-10-24 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Induction and enhancement of the immune response to polysaccharides with bacterial lipoproteins |
| AR003125A1 (es) * | 1995-06-01 | 1998-07-08 | Astra Ab | Antigenos bacterianos para el diagnostico de infecciones con helicobacter pylori, una molecula de adn que lo codifica, un vector, una celula huesped,procedimiento para producir el polipeptido, composiciones para vacunas adecuadas para uso terapeutico y profilactico, el uso del polipeptido en la |
| GB9513074D0 (en) * | 1995-06-27 | 1995-08-30 | Cortecs Ltd | Novel anigen |
| US6207157B1 (en) * | 1996-04-23 | 2001-03-27 | The United States Of America As Represented By The Department Of Health And Human Services | Conjugate vaccine for nontypeable Haemophilus influenzae |
| US20040126381A1 (en) * | 1996-04-23 | 2004-07-01 | Xin-Xing Gu | Intranasal immunization with detoxified lipooligosaccharide from nontypeable haemophilus influenzae or moraxella |
| KR100440836B1 (ko) * | 1997-11-12 | 2004-07-19 | 에프. 호프만-라 로슈 아게 | 레티노이드 길항제를 이용한 제2형 t-보조세포 중재 면역질환의 치료 |
| US6255050B1 (en) * | 1998-05-22 | 2001-07-03 | Lorne Park Research, Inc. | Dynamic hybridization system |
| ATE412007T1 (de) | 1999-06-25 | 2008-11-15 | Wyeth Corp | Extraktion von integralen membranproteinen |
| US7101989B1 (en) | 1999-07-09 | 2006-09-05 | University Of North Carolina At Chapel Hill | DsrA protein and polynucleotides encoding the same |
| US6391313B1 (en) * | 1999-07-15 | 2002-05-21 | Aventis Pasteur Limited | Multi-component vaccine to protect against disease caused by Haemophilus influenzae and Moraxella catarrhalis |
| JP2003507433A (ja) * | 1999-08-20 | 2003-02-25 | ザ ゼネラル ホスピタル コーポレーション | 敗血症治療において治療に用いる対象としての外膜タンパク質a、ペプチドグリカン関連リポタンパク質およびムレインリポタンパク質 |
| US7384640B1 (en) * | 1999-09-30 | 2008-06-10 | Wyeth Holdings Corporation | Mutant cholera holotoxin as an adjuvant |
| CA2418036A1 (en) * | 2000-07-31 | 2002-02-07 | Yale University | Innate immune system-directed vaccines |
| US20030232055A1 (en) * | 2000-07-31 | 2003-12-18 | Ruslan Medzhitov | Innate immune system-directed vaccines |
| GB0025486D0 (en) * | 2000-10-17 | 2000-11-29 | Smithkline Beecham Biolog | Novel compounds |
| US20030175287A1 (en) * | 2001-01-03 | 2003-09-18 | Yale University | Innate immune system-directed vaccines |
| AT410798B (de) * | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| US6834384B2 (en) * | 2001-03-14 | 2004-12-21 | General Instrument Corporation | Methods and apparatus for upgrading firmware in an embedded system |
| CA2446355A1 (en) * | 2001-05-03 | 2002-11-14 | The Government Of The United States Of America | Intranasal immunization with detoxified lipooligosaccharide from nontypeable haemophilus influenzae or moraxella catarrhalis |
| CA2449670A1 (en) * | 2001-06-07 | 2002-12-12 | Wyeth Holdings Corporation | Mutant forms of cholera holotoxin as an adjuvant |
| KR100898648B1 (ko) | 2001-06-07 | 2009-05-22 | 와이어쓰 홀딩스 코포레이션 | 보조제로서 콜레라 홀로톡신의 돌연변이체 형태 |
| WO2002100891A2 (en) * | 2001-06-12 | 2002-12-19 | Glaxosmithkline Biologicals S.A. | Proteins derived from non-typable haemophilus influenzae (nthi) strain |
| GB0117762D0 (en) * | 2001-07-20 | 2001-09-12 | Glaxosmithkline Biolog Sa | Novel compounds |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| NZ535754A (en) | 2002-03-15 | 2007-01-26 | Wyeth Corp | Mutants of the P4 protein of nontypable haemophilus influenzae with reduced enzymatic activity |
| CA2604363C (en) | 2005-04-08 | 2015-06-16 | Wyeth | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| US7709001B2 (en) | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| KR20070047455A (ko) * | 2005-11-02 | 2007-05-07 | 삼성에스디아이 주식회사 | 전자 방출 표시 디바이스 |
| US20070224205A1 (en) | 2006-03-07 | 2007-09-27 | Powell Thomas J | Compositions that include hemagglutinin, methods of making and methods of use thereof |
| EP1915913B1 (en) * | 2006-10-23 | 2015-11-18 | Nestec S.A. | Taste and flavour modulation by biotransformation in milk products |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| US20110294143A1 (en) * | 2009-01-07 | 2011-12-01 | Otsuka Pharmaceutical Co., Ltd. | Method for detecting all haemophilus influenzae |
| KR101594228B1 (ko) | 2010-08-23 | 2016-02-15 | 와이어쓰 엘엘씨 | 네이세리아 메닌기티디스 rLP2086 항원의 안정한 제제 |
| NZ607224A (en) | 2010-09-10 | 2014-11-28 | Wyeth Llc | Non-lipidated variants of neisseria meningitidis orf2086 antigens |
| TW201302779A (zh) | 2011-04-13 | 2013-01-16 | Glaxosmithkline Biolog Sa | 融合蛋白質及組合疫苗 |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| MX359256B (es) | 2012-03-09 | 2018-09-19 | Pfizer | Composiciones de neisseria meningitidis y metodos de las mismas. |
| US9802987B2 (en) | 2013-03-08 | 2017-10-31 | Pfizer Inc. | Immunogenic fusion polypeptides |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| AU2016221318B2 (en) | 2015-02-19 | 2020-06-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| AU2018215585B2 (en) | 2017-01-31 | 2022-03-17 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| EP4034157A1 (en) | 2019-09-27 | 2022-08-03 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4220717A (en) * | 1977-12-22 | 1980-09-02 | American Cyanamid Company | Isolation and purification of polyribosyl ribitol phosphate from Haemophilus influenzae type b. |
| US4220722A (en) | 1978-02-10 | 1980-09-02 | Syva Company | Method for conjugating to polyamino compounds employing haloacyl groups and compositions prepared thereby |
| US4356170A (en) * | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
| US4496538A (en) * | 1982-07-06 | 1985-01-29 | Connaught Laboratories, Inc. | Haemophilus influenzae b polysaccharide-diphtheria toxoid conjugate vaccine |
| US4661347A (en) * | 1982-11-12 | 1987-04-28 | Scripps Clinic | Cytotoxic compositions |
| US4762713A (en) * | 1983-07-05 | 1988-08-09 | The University Of Rochester | Boosting of immunogenic conjugate vaccinations by unconjugated bacterial capsular polymers |
| NZ214503A (en) * | 1984-12-20 | 1990-02-26 | Merck & Co Inc | Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins, and methods of preparing such polysaccharides and conjugates |
| US4873090A (en) * | 1985-03-27 | 1989-10-10 | Broncostat Pty. Limited | Non-adjuvenated vaccine |
| US4707543A (en) * | 1985-09-17 | 1987-11-17 | The United States Of America As Represented By The Secretary Of The Army | Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines |
| JP2534529B2 (ja) * | 1986-07-24 | 1996-09-18 | ブリティシュ・テレコミュニケ−ションズ・パブリック・リミテッド・カンパニ | 放射発生器 |
| US5173294A (en) * | 1986-11-18 | 1992-12-22 | Research Foundation Of State University Of New York | Dna probe for the identification of haemophilus influenzae |
| AU623353B2 (en) * | 1987-12-10 | 1992-05-14 | Board Of Regents, The University Of Texas System | Methods and compositions for the production of haemophilus influenzae type b major outer membrane protein antigens |
-
1990
- 1990-03-09 DE DE69033600T patent/DE69033600T2/de not_active Expired - Lifetime
- 1990-03-09 DK DK90905112.0T patent/DK0462210T3/da active
- 1990-03-09 US US07/491,466 patent/US5601831A/en not_active Expired - Lifetime
- 1990-03-09 AU AU53326/90A patent/AU648251B2/en not_active Expired
- 1990-03-09 WO PCT/US1990/001317 patent/WO1990010458A1/en not_active Ceased
- 1990-03-09 KR KR1019910701102A patent/KR100188323B1/ko not_active Expired - Lifetime
- 1990-03-09 DE DE69012318T patent/DE69012318T2/de not_active Expired - Lifetime
- 1990-03-09 JP JP2505084A patent/JP2955014B2/ja not_active Expired - Lifetime
- 1990-03-09 FI FI914241A patent/FI914241A0/fi not_active Application Discontinuation
- 1990-03-09 AT AT94100492T patent/ATE195076T1/de not_active IP Right Cessation
- 1990-03-09 ES ES90905112T patent/ES2063965T3/es not_active Expired - Lifetime
- 1990-03-09 EP EP90905112A patent/EP0462210B1/en not_active Expired - Lifetime
- 1990-03-09 DK DK94100492T patent/DK0606921T3/da active
- 1990-03-09 AT AT90905112T patent/ATE110965T1/de not_active IP Right Cessation
- 1990-03-09 CA CA002047681A patent/CA2047681C/en not_active Expired - Lifetime
- 1990-03-09 ES ES94100492T patent/ES2150450T3/es not_active Expired - Lifetime
- 1990-03-09 EP EP94100492A patent/EP0606921B1/en not_active Expired - Lifetime
-
1991
- 1991-09-06 NO NO91913518A patent/NO913518L/no unknown
-
1995
- 1995-05-23 US US08/448,097 patent/US6420134B1/en not_active Expired - Fee Related
- 1995-05-23 US US08/449,406 patent/US5955580A/en not_active Expired - Lifetime
- 1995-05-23 US US08/447,653 patent/US5780601A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FI914241A7 (fi) | 1991-09-09 |
| JP2955014B2 (ja) | 1999-10-04 |
| DE69012318T2 (de) | 1995-03-09 |
| EP0606921A1 (en) | 1994-07-20 |
| KR100188323B1 (ko) | 1999-06-01 |
| NO913518D0 (no) | 1991-09-06 |
| CA2047681C (en) | 2000-02-01 |
| US6420134B1 (en) | 2002-07-16 |
| ES2150450T3 (es) | 2000-12-01 |
| JPH07508972A (ja) | 1995-10-05 |
| ATE110965T1 (de) | 1994-09-15 |
| NO913518L (no) | 1991-10-29 |
| EP0462210A1 (en) | 1991-12-27 |
| EP0462210B1 (en) | 1994-09-07 |
| DE69012318D1 (de) | 1994-10-13 |
| ES2063965T3 (es) | 1995-01-16 |
| WO1990010458A1 (en) | 1990-09-20 |
| US5955580A (en) | 1999-09-21 |
| CA2047681A1 (en) | 1990-09-10 |
| DE69033600D1 (de) | 2000-09-07 |
| DE69033600T2 (de) | 2001-04-05 |
| DK0462210T3 (da) | 1994-10-10 |
| US5601831A (en) | 1997-02-11 |
| US5780601A (en) | 1998-07-14 |
| AU648251B2 (en) | 1994-04-21 |
| ATE195076T1 (de) | 2000-08-15 |
| AU5332690A (en) | 1990-10-09 |
| EP0606921B1 (en) | 2000-08-02 |
| FI914241A0 (fi) | 1991-09-09 |
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