DK0609643T3 - Fremgangsmåde til fremstilling af L-(-)carnitin ud fra et spildprodukt med modsat konfiguration - Google Patents

Fremgangsmåde til fremstilling af L-(-)carnitin ud fra et spildprodukt med modsat konfiguration

Info

Publication number
DK0609643T3
DK0609643T3 DK93830506.7T DK93830506T DK0609643T3 DK 0609643 T3 DK0609643 T3 DK 0609643T3 DK 93830506 T DK93830506 T DK 93830506T DK 0609643 T3 DK0609643 T3 DK 0609643T3
Authority
DK
Denmark
Prior art keywords
carnitine
preparing
waste product
opposite configuration
lactone
Prior art date
Application number
DK93830506.7T
Other languages
English (en)
Inventor
Fabio Giannessi
Maria Ornella Tinti
Maria Laura Bolognesi
Francesco De Angelis
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK0609643T3 publication Critical patent/DK0609643T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
    • C07D305/12—Beta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Processing Of Solid Wastes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK93830506.7T 1992-12-21 1993-12-15 Fremgangsmåde til fremstilling af L-(-)carnitin ud fra et spildprodukt med modsat konfiguration DK0609643T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM920915A IT1256705B (it) 1992-12-21 1992-12-21 Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione.

Publications (1)

Publication Number Publication Date
DK0609643T3 true DK0609643T3 (da) 1996-11-11

Family

ID=11401346

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93830506.7T DK0609643T3 (da) 1992-12-21 1993-12-15 Fremgangsmåde til fremstilling af L-(-)carnitin ud fra et spildprodukt med modsat konfiguration

Country Status (12)

Country Link
US (2) US5412113A (da)
EP (1) EP0609643B1 (da)
JP (1) JP3502649B2 (da)
KR (1) KR100294780B1 (da)
AT (1) ATE140694T1 (da)
CA (1) CA2111898C (da)
DE (1) DE69303807T2 (da)
DK (1) DK0609643T3 (da)
ES (1) ES2090945T3 (da)
GR (1) GR3020617T3 (da)
IT (1) IT1256705B (da)
ZA (1) ZA939444B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1240760B (it) * 1990-02-12 1993-12-17 Sigma Tau Ind Farmaceuti Esteri di acil-l-carnitine con l'acido gamma-idrossibutirrico e composizioni farmaceutiche che li contengono per l'inibizione della degenerazione neuronale e nel trattamento del coma.
IT1261230B (it) * 1993-04-08 1996-05-09 Sigma Tau Ind Farmaceuti Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da suoi precursori aventi opposta configurazione.
IT1261828B (it) 1993-07-14 1996-06-03 Sigma Tau Ind Farmaceuti Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico.
IT1276207B1 (it) * 1995-09-29 1997-10-27 Sigma Tau Ind Farmaceuti Procedimento per la preparazione del (s)-b-idrossi-gamma- butirrolattone
IT1277953B1 (it) * 1995-12-21 1997-11-12 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per
IT1297120B1 (it) * 1997-12-16 1999-08-03 Sigma Tau Ind Farmaceuti Procedimento per la produzione di (r)-3-idrossi-4-butirrolattone utile nella preparazione della (r)-carnitina
IT1299182B1 (it) 1998-05-29 2000-02-29 Sigma Tau Ind Farmaceuti Procedimento chimico per la sintesi stereoselettiva della r-(-)- carnitina.
IT1301977B1 (it) * 1998-07-31 2000-07-20 Sigma Tau Ind Farmaceuti Procedimento per la preparazione di r-(-)-carnitina
IT1307303B1 (it) 1999-12-23 2001-10-30 Sigma Tau Ind Farmaceuti Idrolisi stereospecifica di esteri otticamente attivi.
IT1306184B1 (it) * 1999-08-05 2001-05-30 Sigma Tau Ind Farmaceuti Nitrilossi derivati della (r) e (s)-carnitina.
CA2383814C (en) * 1999-09-03 2010-08-17 Sigma-Tau Healthscience S.P.A. Ultrafine l-carnitine, methods of preparing the same, compositions containing the same, and methods of using the same
DE10027393B4 (de) * 2000-06-02 2007-05-16 Wella Ag Poly- und Oligoester kationischer Hydroxysäuren, Verfahren zu ihrer Herstellung und ihre Verwendung
EP2595973B1 (en) * 2010-07-21 2017-07-12 Lonza Ltd. A process for the production of carnitine from beta-lactones
DK3164125T3 (da) 2014-07-03 2023-12-18 Silti Ag Fremgangsmåder og sammensætninger til behandling af overvægt, forhindring af vægtforøgelse, fremme vægttab, fremme slankning eller behandling eller forebyggelse af udvikling af diabetes
CN115057789B (zh) * 2022-06-30 2024-04-02 中科萱嘉医养(珠海)健康科技有限公司 一种左旋肉碱离子液体及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3830931A (en) 1972-11-06 1974-08-20 Felice S De Carnitine and its use in the treatment of arrhythmia and impaired cardiac function
IT1156852B (it) * 1978-07-10 1987-02-04 Sigma Tau Ind Farmaceuti Procedimento industriale per la preparazione del d'canforato della l carnitinammide e del d canforato della d carnitinammide e sue applicazioni
IT1136945B (it) * 1981-03-18 1986-09-03 Anic Spa Processo per la preparazione di l-carnitina
US5200526A (en) * 1987-04-27 1993-04-06 The Governors Of The University Of Alberta Syntheses of optically pure α-amino acids from 3-amino-2-oxetanone salts

Also Published As

Publication number Publication date
US5412113A (en) 1995-05-02
ATE140694T1 (de) 1996-08-15
CA2111898C (en) 2004-04-27
EP0609643A1 (en) 1994-08-10
IT1256705B (it) 1995-12-12
GR3020617T3 (en) 1996-10-31
ES2090945T3 (es) 1996-10-16
JP3502649B2 (ja) 2004-03-02
JPH06199751A (ja) 1994-07-19
CA2111898A1 (en) 1994-06-22
KR940014303A (ko) 1994-07-18
ITRM920915A0 (it) 1992-12-21
ITRM920915A1 (it) 1994-06-21
HK1005861A1 (en) 1999-01-29
DE69303807T2 (de) 1996-11-28
EP0609643B1 (en) 1996-07-24
KR100294780B1 (ko) 2001-09-17
DE69303807D1 (de) 1996-08-29
ZA939444B (en) 1994-08-09
US5599978A (en) 1997-02-04

Similar Documents

Publication Publication Date Title
DK0609643T3 (da) Fremgangsmåde til fremstilling af L-(-)carnitin ud fra et spildprodukt med modsat konfiguration
BR9306101A (pt) Processo para a produção de ésteres cíclicos a partir de hidróxi ácidos e derivados dos mesmos
GB2014134B (en) 1,4-dihydropyridine 3,5-dicarboxylic acid ester derivatives and process of producing them
PL304894A1 (en) Derivatives of vinylene azanidole and method of obtaining them
LV10269A (lv) Dialkoksipiridinilbenzimidazola atvasinajumi farmaceitiskas kompozicijas inhibesanas panemiens izmantosana
KR960704082A (ko) 저 잔자성 재료로 이루어진 하나이상의 부재의 처리방법(Method to process at least one member of low-retentivity)
ATE150769T1 (de) Zelluloseesterzusammensetzungen und verfahren zu deren herstellung
BR8902562A (pt) Processo de produzir um dispositivo sensivel a radiacao
FI981585A7 (fi) Interleukiini-4:n käyttöjä - ja menetelmä sen puhdistamiseksi
EP0402322A3 (en) Process for the production of r(+)-aminocarnitine and s(-)-amino-carnitine
BR8801834A (pt) Processo para produzir uma lactona
FI102083B (fi) Menetelmä L-karnitiinin valmistamiseksi epäjatkuvasti mikrobiologista tietä
TW377341B (en) Process for manufacturing L-(-)-carnitine from a waste product having opposite configuration
IT1261231B (it) Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione.
ES2017900A4 (es) Derivados de acido tiazolidina-4-carboxilico, su preparacion y composiciones farmaceuticas conteniendolo
ATE131155T1 (de) Verfahren zur herstellung von zwischenprodukten und zur synthese von n-(2-hydroxyethyl)-2- hydroxymethyl-3,4,5-trihydroxypiperidine.
FI905930A7 (fi) Menetelmä uusien, farmakologisesti käyttökelpoisten bispilokarpiinihapon esterijohdannaisten valmistamiseksi
FR2631727B1 (fr) Procede et dispositif de production de modeles de pieces industrielles par action de la lumiere
BR9106926A (pt) Processo e método de alteraçao de uma planta
PT90844A (pt) Processo de preparacao de derivados de lactol
RU1803410C (ru) Производные декстранов в качестве адсорбента желчных кислот и способ их получени
IS1743B (is) Hliðstæð aðferð við að framleiða nýjar (1-fenýl-1-heterósýklýl)metanól- og (1-fenýl-1-heterósýklýl)metýlamínafleiður
FR2641784B1 (fr) Procede de preparation de derives du chromanne et intermediaires de synthese
BR9611540A (pt) Processo de fazer derivados de ácido 3-fenil-1-metilenodioxifenil-indano-2-carboxílico
DK0383316T3 (da) Fremgangsmåde til enantiomer-opspaltning af et benzopyranderivat