ATE140694T1 - Verfahren zur herstellung einer l-(-)carnitin aus einem abfallprodukt mit der gegengesetzter konfiguration - Google Patents
Verfahren zur herstellung einer l-(-)carnitin aus einem abfallprodukt mit der gegengesetzter konfigurationInfo
- Publication number
- ATE140694T1 ATE140694T1 AT93830506T AT93830506T ATE140694T1 AT E140694 T1 ATE140694 T1 AT E140694T1 AT 93830506 T AT93830506 T AT 93830506T AT 93830506 T AT93830506 T AT 93830506T AT E140694 T1 ATE140694 T1 AT E140694T1
- Authority
- AT
- Austria
- Prior art keywords
- carnitine
- producing
- waste product
- opposite configuration
- lactone
- Prior art date
Links
- PHIQHXFUZVPYII-UHFFFAOYSA-N carnitine Chemical compound C[N+](C)(C)CC(O)CC([O-])=O PHIQHXFUZVPYII-UHFFFAOYSA-N 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000002699 waste material Substances 0.000 title 1
- PHIQHXFUZVPYII-LURJTMIESA-N (S)-carnitine Chemical compound C[N+](C)(C)C[C@@H](O)CC([O-])=O PHIQHXFUZVPYII-LURJTMIESA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 150000002596 lactones Chemical class 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
- C07D305/12—Beta-lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Epoxy Compounds (AREA)
- Processing Of Solid Wastes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM920915A IT1256705B (it) | 1992-12-21 | 1992-12-21 | Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE140694T1 true ATE140694T1 (de) | 1996-08-15 |
Family
ID=11401346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93830506T ATE140694T1 (de) | 1992-12-21 | 1993-12-15 | Verfahren zur herstellung einer l-(-)carnitin aus einem abfallprodukt mit der gegengesetzter konfiguration |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5412113A (de) |
| EP (1) | EP0609643B1 (de) |
| JP (1) | JP3502649B2 (de) |
| KR (1) | KR100294780B1 (de) |
| AT (1) | ATE140694T1 (de) |
| CA (1) | CA2111898C (de) |
| DE (1) | DE69303807T2 (de) |
| DK (1) | DK0609643T3 (de) |
| ES (1) | ES2090945T3 (de) |
| GR (1) | GR3020617T3 (de) |
| IT (1) | IT1256705B (de) |
| ZA (1) | ZA939444B (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1240760B (it) * | 1990-02-12 | 1993-12-17 | Sigma Tau Ind Farmaceuti | Esteri di acil-l-carnitine con l'acido gamma-idrossibutirrico e composizioni farmaceutiche che li contengono per l'inibizione della degenerazione neuronale e nel trattamento del coma. |
| IT1261230B (it) * | 1993-04-08 | 1996-05-09 | Sigma Tau Ind Farmaceuti | Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da suoi precursori aventi opposta configurazione. |
| IT1261828B (it) | 1993-07-14 | 1996-06-03 | Sigma Tau Ind Farmaceuti | Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico. |
| IT1276207B1 (it) * | 1995-09-29 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione del (s)-b-idrossi-gamma- butirrolattone |
| IT1277953B1 (it) * | 1995-12-21 | 1997-11-12 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per |
| IT1297120B1 (it) * | 1997-12-16 | 1999-08-03 | Sigma Tau Ind Farmaceuti | Procedimento per la produzione di (r)-3-idrossi-4-butirrolattone utile nella preparazione della (r)-carnitina |
| IT1299182B1 (it) | 1998-05-29 | 2000-02-29 | Sigma Tau Ind Farmaceuti | Procedimento chimico per la sintesi stereoselettiva della r-(-)- carnitina. |
| IT1301977B1 (it) * | 1998-07-31 | 2000-07-20 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione di r-(-)-carnitina |
| IT1307303B1 (it) | 1999-12-23 | 2001-10-30 | Sigma Tau Ind Farmaceuti | Idrolisi stereospecifica di esteri otticamente attivi. |
| IT1306184B1 (it) * | 1999-08-05 | 2001-05-30 | Sigma Tau Ind Farmaceuti | Nitrilossi derivati della (r) e (s)-carnitina. |
| CA2383814C (en) * | 1999-09-03 | 2010-08-17 | Sigma-Tau Healthscience S.P.A. | Ultrafine l-carnitine, methods of preparing the same, compositions containing the same, and methods of using the same |
| DE10027393B4 (de) * | 2000-06-02 | 2007-05-16 | Wella Ag | Poly- und Oligoester kationischer Hydroxysäuren, Verfahren zu ihrer Herstellung und ihre Verwendung |
| EP2595973B1 (de) * | 2010-07-21 | 2017-07-12 | Lonza Ltd. | Verfahren zur herstellung von carnitin aus beta-lactonen |
| DK3164125T3 (da) | 2014-07-03 | 2023-12-18 | Silti Ag | Fremgangsmåder og sammensætninger til behandling af overvægt, forhindring af vægtforøgelse, fremme vægttab, fremme slankning eller behandling eller forebyggelse af udvikling af diabetes |
| CN115057789B (zh) * | 2022-06-30 | 2024-04-02 | 中科萱嘉医养(珠海)健康科技有限公司 | 一种左旋肉碱离子液体及其制备方法与应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3830931A (en) | 1972-11-06 | 1974-08-20 | Felice S De | Carnitine and its use in the treatment of arrhythmia and impaired cardiac function |
| IT1156852B (it) * | 1978-07-10 | 1987-02-04 | Sigma Tau Ind Farmaceuti | Procedimento industriale per la preparazione del d'canforato della l carnitinammide e del d canforato della d carnitinammide e sue applicazioni |
| IT1136945B (it) * | 1981-03-18 | 1986-09-03 | Anic Spa | Processo per la preparazione di l-carnitina |
| US5200526A (en) * | 1987-04-27 | 1993-04-06 | The Governors Of The University Of Alberta | Syntheses of optically pure α-amino acids from 3-amino-2-oxetanone salts |
-
1992
- 1992-12-21 IT ITRM920915A patent/IT1256705B/it active IP Right Grant
-
1993
- 1993-03-28 ZA ZA939444A patent/ZA939444B/xx unknown
- 1993-12-15 AT AT93830506T patent/ATE140694T1/de not_active IP Right Cessation
- 1993-12-15 ES ES93830506T patent/ES2090945T3/es not_active Expired - Lifetime
- 1993-12-15 EP EP93830506A patent/EP0609643B1/de not_active Expired - Lifetime
- 1993-12-15 DK DK93830506.7T patent/DK0609643T3/da active
- 1993-12-15 DE DE69303807T patent/DE69303807T2/de not_active Expired - Lifetime
- 1993-12-20 JP JP31979293A patent/JP3502649B2/ja not_active Expired - Fee Related
- 1993-12-20 CA CA002111898A patent/CA2111898C/en not_active Expired - Fee Related
- 1993-12-20 KR KR1019930028618A patent/KR100294780B1/ko not_active Expired - Fee Related
- 1993-12-21 US US08/170,764 patent/US5412113A/en not_active Expired - Lifetime
-
1995
- 1995-01-03 US US08/367,863 patent/US5599978A/en not_active Expired - Lifetime
-
1996
- 1996-07-25 GR GR960401768T patent/GR3020617T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5412113A (en) | 1995-05-02 |
| CA2111898C (en) | 2004-04-27 |
| EP0609643A1 (de) | 1994-08-10 |
| IT1256705B (it) | 1995-12-12 |
| GR3020617T3 (en) | 1996-10-31 |
| DK0609643T3 (da) | 1996-11-11 |
| ES2090945T3 (es) | 1996-10-16 |
| JP3502649B2 (ja) | 2004-03-02 |
| JPH06199751A (ja) | 1994-07-19 |
| CA2111898A1 (en) | 1994-06-22 |
| KR940014303A (ko) | 1994-07-18 |
| ITRM920915A0 (it) | 1992-12-21 |
| ITRM920915A1 (it) | 1994-06-21 |
| HK1005861A1 (en) | 1999-01-29 |
| DE69303807T2 (de) | 1996-11-28 |
| EP0609643B1 (de) | 1996-07-24 |
| KR100294780B1 (ko) | 2001-09-17 |
| DE69303807D1 (de) | 1996-08-29 |
| ZA939444B (en) | 1994-08-09 |
| US5599978A (en) | 1997-02-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |