DK0613465T3 - 1,3-Sustituerede cycloalkener og cycloalkaner med virkning på centralnervesystemet - Google Patents

1,3-Sustituerede cycloalkener og cycloalkaner med virkning på centralnervesystemet

Info

Publication number: DK0613465T3
Authority: DK; Denmark
Prior art keywords: nervous system; central nervous; cycloalkanes; effect; substituted cycloalkenes
Prior art date: 1991-11-20

Application number

DK92925105T

Other languages

Danish (da)

English (en)

Inventor

Lawrence David Wise

Bradley William Caprathe

Dennis Michael Downing

Juan Carlos Jaen

Stephen Joseph Johnson

William John Smith Iii

Jonathan Wright

David Juergen Wustrow

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-11-20

Filing date

1992-11-05

Publication date

2002-02-04

1992-11-05 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

2002-02-04 Application granted granted Critical

2002-02-04 Publication of DK0613465T3 publication Critical patent/DK0613465T3/da

Links

150000001924 cycloalkanes Chemical class 0.000 title abstract 2
150000001925 cycloalkenes Chemical class 0.000 title abstract 2
210000003169 central nervous system Anatomy 0.000 title 1
230000000561 anti-psychotic effect Effects 0.000 abstract 1
229940030600 antihypertensive agent Drugs 0.000 abstract 1
239000002220 antihypertensive agent Substances 0.000 abstract 1
239000000164 antipsychotic agent Substances 0.000 abstract 1
239000003576 central nervous system agent Substances 0.000 abstract 1
229940125693 central nervous system agent Drugs 0.000 abstract 1
208000015114 central nervous system disease Diseases 0.000 abstract 1
239000003136 dopamine receptor stimulating agent Substances 0.000 abstract 1
230000003291 dopaminomimetic effect Effects 0.000 abstract 1
208000031424 hyperprolactinemia Diseases 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/08—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing alicyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychology (AREA)
Heart & Thoracic Surgery (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)
Luminescent Compositions (AREA)
Manufacture Of Tobacco Products (AREA)
Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DK92925105T 1991-11-20 1992-11-05 1,3-Sustituerede cycloalkener og cycloalkaner med virkning på centralnervesystemet DK0613465T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US79520791A	1991-11-20	1991-11-20
US07/957,277 US5314896A (en)	1991-11-20	1992-10-15	1,3-substituted cycloalkenes and cycloalkanes as central nervous system agents
PCT/US1992/009583 WO1993010092A1 (en)	1991-11-20	1992-11-05	1,3-substituted cycloalkenes and cycloalkanes as central nervous system agents

Publications (1)

Publication Number	Publication Date
DK0613465T3 true DK0613465T3 (da)	2002-02-04

Family

ID=27121601

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK92925105T DK0613465T3 (da)	1991-11-20	1992-11-05	1,3-Sustituerede cycloalkener og cycloalkaner med virkning på centralnervesystemet

Country Status (20)

Country	Link
US (2)	US5314896A (de)
EP (2)	EP0545095A1 (de)
JP (1)	JP3193718B2 (de)
KR (1)	KR100234600B1 (de)
AT (1)	ATE206398T1 (de)
AU (1)	AU664872B2 (de)
CA (1)	CA2122911C (de)
CZ (1)	CZ284181B6 (de)
DE (1)	DE69232099T2 (de)
DK (1)	DK0613465T3 (de)
ES (1)	ES2165360T3 (de)
FI (2)	FI106259B (de)
HU (1)	HU218935B (de)
NO (1)	NO180632C (de)
NZ (1)	NZ245174A (de)
PT (1)	PT613465E (de)
RU (1)	RU2116297C1 (de)
SG (1)	SG46641A1 (de)
SK (1)	SK280812B6 (de)
WO (1)	WO1993010092A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5401692A (en) *	1993-06-15	1995-03-28	Texas Instruments Incorporated	Method for minimizing particle generation on a wafer surface during high pressure oxidation of silicon
US5468768A (en) *	1994-01-06	1995-11-21	Bristol-Myers Squibb Company	Antimigraine derivatives of indolylcycloalkanylamines
US5468767A (en) *	1994-01-06	1995-11-21	Bristol-Myers Squibb Company	Antidepressant 3-(aminocycloalkenyl)-indole-5-nitrile derivatives
US5710277A (en) *	1994-09-12	1998-01-20	Warner-Lambert Company	Process for R (+) 1,2,3,6-tetrahydro-4-phenyl-1- (3-phenyl-3-cyclohexen-1-yl)methyl!pyridine, a central nervous system agent
US5773616A (en) *	1995-02-15	1998-06-30	Neurogen Corporation	Certain bridged 4-phenyl-2-aminomethylimidazoles; new dopamine receptor subtype specific ligands
WO1996025411A1 (en) *	1995-02-15	1996-08-22	Neurogen Corporation	Certain bridged 4-phenyl-2-aminomethylimidazoles; new dopamine receptor subtype specific ligands
KR19980703192A (ko) *	1995-03-22	1998-10-15	우에하라아끼라	티아졸 유도체
US5656632A (en) *	1995-06-05	1997-08-12	Neurogen Corporation	1-(N'-(arylalkylaminoalkyl)) aminoisoindoles; dopamine receptor subtype specific ligands
US6245768B1 (en)	1995-06-05	2001-06-12	Neurogen Corporation	1-(N′-(arylalkylaminoalkyl)) aminoisoindoles; a new class of dopamine receptor subtype specific ligands
US5602168A (en) *	1995-07-10	1997-02-11	Neurogen Corporation	1-(N'-(arylalkylaminoalkyl)) aminoisoindoles; dopamine receptor subtype specific ligands
US5633724A (en) *	1995-08-29	1997-05-27	Hewlett-Packard Company	Evanescent scanning of biochemical array
GB9523462D0 (en) *	1995-11-16	1996-01-17	Merck Sharp & Dohme	Therapeutic agents
CN1160332C (zh) *	1998-04-08	2004-08-04	惠氏公司	用于治疗抑郁症的n-芳氧基乙基胺衍生物
US6200994B1 (en)	1999-01-07	2001-03-13	American Home Products Corp	1,4-Disubstituted cyclohexane derivatives for the treatment of depression
ATE223406T1 (de) *	1999-01-07	2002-09-15	Wyeth Corp	1,4-disubstitutierte cyclohexanderivate zur behandlung von depression
US6313126B1 (en)	1999-01-07	2001-11-06	American Home Products Corp	Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression
US6245780B1 (en) *	1999-04-22	2001-06-12	American Home Products Corp	Tetrahydroisoquinolinyl-indole derivatives for the treatment of depression
IL148218A0 (en)	1999-08-23	2002-09-12	Solvay Pharm Bv	New phenylpiperazines
US6780305B2 (en) *	2001-02-20	2004-08-24	Fuji Photo Film Co., Ltd.	Method for producing support for planographic printing plate, support for planographic printing plate, and planographic printing plate precursor
AR032712A1 (es) *	2001-02-21	2003-11-19	Solvay Pharm Bv	Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen
US20040197284A1 (en)	2003-04-04	2004-10-07	Frederic Auguste	Cosmetic composition comprising a volatile fatty phase
UY28538A1 (es) *	2003-09-26	2005-04-29	Vertex Pharma	Derivados de fenil-piperazina como moduladores de receptores muscarínicos
CA2672727A1 (en) *	2006-12-21	2008-07-03	Abbott Laboratories	Sphingosine-1-phosphate receptor agonist and antagonist compounds
EP2102145A4 (de)	2006-12-21	2014-06-18	Abbott Lab	Verfahren zur herstellung und isolierung der einzelnen stereoisomere von 1-amino-3-substituierten phenylcyclopentancarboxylaten
US8217027B2 (en)	2006-12-21	2012-07-10	Abbott Laboratories	Sphingosine-1-phosphate receptor agonist and antagonist compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4597921A (en) *	1984-07-26	1986-07-01	Northern Telecom Limited	Provision of plastic insulation upon an electrical conductor
US4954502A (en) *	1988-06-10	1990-09-04	Bristol-Myers Squibb Company	1-indolyalkyl-4-(substituted-pyridinyl)piperazines
US4975445A (en) *	1989-12-06	1990-12-04	Warner-Lambert Company	Substituted cyclohexenes as central nervous system agents
US4957921A (en) *	1989-12-06	1990-09-18	Warner-Lambert Company	Substituted cyclohexanols as central nervous system agents
US5124332A (en) *	1991-01-28	1992-06-23	Warner-Lambert Company	Substituted indoles as central nervous system agents

1992
- 1992-10-15 US US07/957,277 patent/US5314896A/en not_active Expired - Fee Related
- 1992-11-05 CZ CZ941161A patent/CZ284181B6/cs not_active IP Right Cessation
- 1992-11-05 DK DK92925105T patent/DK0613465T3/da active
- 1992-11-05 JP JP50933393A patent/JP3193718B2/ja not_active Expired - Fee Related
- 1992-11-05 AT AT92925105T patent/ATE206398T1/de not_active IP Right Cessation
- 1992-11-05 SK SK569-94A patent/SK280812B6/sk unknown
- 1992-11-05 SG SG1996006952A patent/SG46641A1/en unknown
- 1992-11-05 RU RU94028888/04A patent/RU2116297C1/ru not_active IP Right Cessation
- 1992-11-05 AU AU31291/93A patent/AU664872B2/en not_active Ceased
- 1992-11-05 KR KR1019940701684A patent/KR100234600B1/ko not_active Expired - Fee Related
- 1992-11-05 EP EP92118998A patent/EP0545095A1/de active Pending
- 1992-11-05 ES ES92925105T patent/ES2165360T3/es not_active Expired - Lifetime
- 1992-11-05 HU HU9401468A patent/HU218935B/hu not_active IP Right Cessation
- 1992-11-05 DE DE69232099T patent/DE69232099T2/de not_active Expired - Fee Related
- 1992-11-05 PT PT92925105T patent/PT613465E/pt unknown
- 1992-11-05 WO PCT/US1992/009583 patent/WO1993010092A1/en not_active Ceased
- 1992-11-05 CA CA002122911A patent/CA2122911C/en not_active Expired - Fee Related
- 1992-11-05 EP EP92925105A patent/EP0613465B1/de not_active Expired - Lifetime
- 1992-11-18 NZ NZ245174A patent/NZ245174A/en unknown
1994
- 1994-02-04 US US08/192,238 patent/US5409931A/en not_active Expired - Fee Related
- 1994-05-18 FI FI942310A patent/FI106259B/fi not_active IP Right Cessation
- 1994-05-19 NO NO941884A patent/NO180632C/no not_active IP Right Cessation
1998
- 1998-03-02 FI FI980471A patent/FI107383B/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
JP3193718B2 (ja)	2001-07-30
AU664872B2 (en)	1995-12-07
EP0545095A1 (de)	1993-06-09
EP0613465B1 (de)	2001-10-04
SK280812B6 (sk)	2000-08-14
NZ245174A (en)	1995-09-26
NO180632C (no)	1997-05-21
CZ116194A3 (en)	1994-11-16
US5409931A (en)	1995-04-25
NO941884D0 (no)	1994-05-19
RU94028888A (ru)	1997-02-20
JPH07501075A (ja)	1995-02-02
SG46641A1 (en)	1998-02-20
FI942310L (fi)	1994-07-15
US5314896A (en)	1994-05-24
ES2165360T3 (es)	2002-03-16
DE69232099D1 (de)	2001-11-08
FI942310A0 (fi)	1994-05-18
FI107383B (fi)	2001-07-31
SK56994A3 (en)	1995-02-08
ATE206398T1 (de)	2001-10-15
DE69232099T2 (de)	2002-06-06
CZ284181B6 (cs)	1998-09-16
RU2116297C1 (ru)	1998-07-27
FI980471A0 (fi)	1998-03-02
FI106259B (fi)	2000-12-29
KR100234600B1 (ko)	1999-12-15
CA2122911C (en)	2003-10-14
AU3129193A (en)	1993-06-15
PT613465E (pt)	2002-03-28
WO1993010092A1 (en)	1993-05-27
FI980471L (fi)	1998-03-02
NO941884L (no)	1994-05-19
CA2122911A1 (en)	1993-05-27
HUT70520A (en)	1995-10-30
EP0613465A1 (de)	1994-09-07
HU9401468D0 (en)	1994-08-29
NO180632B (no)	1997-02-10
HU218935B (hu)	2001-01-29

Publication	Publication Date	Title
FI942310A0 (fi)	1994-05-18	1,3-substituoidut sykloalkeenit ja sykloalkaanit keskushermostoon vaikuttavina aineina
DK0431580T3 (da)	1995-07-24	Substituerede cyclohexanoler med virkning på centralnervesystemet
FI915920A0 (fi)	1991-12-16	Serotoninantagonister.
CA2094702A1 (en)	1992-05-06	Substituted tetrahydropyridines and hydroxypiperidines as central nervous system agents
GR3019490T3 (en)	1996-07-31	Substituted piperazines as central nervous system agents
DK0431579T3 (da)	1994-10-31	Substituerede cyclohexener som midler med virkning på centralnervesystemet
PT889044E (pt)	2005-01-31	Derivados do 5-(heteroaril)alquil-3-oxo-pirido-(1,2-a)benzimidazole-4-carboxamida (pbi) uteis no tratamento de perturbacoes do sistema nervoso central
MX9206635A (es)	1994-07-29	Cicloalquenos y cicloalcanos 1,3-substituidos como agentes del sistema nervioso central.
MX9302225A (es)	1994-04-29	Cicloalquenos y cicloalcanos 1,3-substituidos como agentes del sistema nervioso central.