DK0614455T3 - Vitamin D-amidderivater - Google Patents

Vitamin D-amidderivater

Info

Publication number: DK0614455T3
Authority: DK; Denmark
Prior art keywords: vitamin; amide derivatives; alpha; azacholesta; seco
Prior art date: 1991-11-07

Application number

DK92922932.6T

Other languages

Danish (da)

English (en)

Inventor

Robert Henry Hesse

Gaddam Subba Reddy

Sundara Katugam S Setty

Original Assignee

Res Inst Medicine Chem

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-11-07

Filing date

1992-11-06

Publication date

1996-03-18

1991-11-07 Priority claimed from GB919123712A external-priority patent/GB9123712D0/en

1992-05-05 Priority claimed from GB929209658A external-priority patent/GB9209658D0/en

1992-11-06 Application filed by Res Inst Medicine Chem filed Critical Res Inst Medicine Chem

1996-03-18 Application granted granted Critical

1996-03-18 Publication of DK0614455T3 publication Critical patent/DK0614455T3/da

Links

-1 Vitamin D amide Chemical class 0.000 title abstract 2
229930003316 Vitamin D Natural products 0.000 title 1
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title 1
235000019166 vitamin D Nutrition 0.000 title 1
239000011710 vitamin D Substances 0.000 title 1
229940046008 vitamin d Drugs 0.000 title 1
125000004450 alkenylene group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Immunology (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)

DK92922932.6T 1991-11-07 1992-11-06 Vitamin D-amidderivater DK0614455T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB919123712A GB9123712D0 (en)	1991-11-07	1991-11-07	Chemical compounds
GB929209658A GB9209658D0 (en)	1992-05-05	1992-05-05	Chemical compounds

Publications (1)

Publication Number	Publication Date
DK0614455T3 true DK0614455T3 (da)	1996-03-18

Family

ID=26299825

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK92922932.6T DK0614455T3 (da)	1991-11-07	1992-11-06	Vitamin D-amidderivater

Country Status (20)

Country	Link
US (2)	US5494905A (pl)
EP (1)	EP0614455B1 (pl)
JP (1)	JP3282811B2 (pl)
KR (1)	KR100271461B1 (pl)
AT (1)	ATE134366T1 (pl)
AU (1)	AU664213B2 (pl)
CA (1)	CA2121678C (pl)
CZ (1)	CZ288031B6 (pl)
DE (1)	DE69208478T2 (pl)
DK (1)	DK0614455T3 (pl)
ES (1)	ES2083771T3 (pl)
FI (1)	FI106119B (pl)
GR (1)	GR3019601T3 (pl)
HU (1)	HU221008B1 (pl)
NO (1)	NO305315B1 (pl)
NZ (1)	NZ245041A (pl)
PL (1)	PL171580B1 (pl)
RU (1)	RU2139276C1 (pl)
SK (1)	SK281302B6 (pl)
WO (1)	WO1993009093A1 (pl)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0614455B1 (en) *	1991-11-07	1996-02-21	Research Institute For Medicine And Chemistry Inc.	Vitamin d amide derivatives
IL107185A (en) *	1992-10-06	1998-02-22	Schering Ag	Vitamin d, 25-carboxylic acid derivatives and pharmaceutical compositions containing the same
WO2004076688A1 (ja) *	1993-02-12	2004-09-10	Etsuro Ogata	無症候腎障害のモニタリング法
GB9309422D0 (en) *	1993-05-07	1993-06-23	Res Inst Medicine Chem	Chemical compounds
GB9325415D0 (en) *	1993-12-13	1994-02-16	Res Inst Medicine Chem	Chemical compounds
GB9405715D0 (en) *	1994-03-23	1994-05-11	Res Inst Medicine Chem	Chemical compounds
US5661141A (en) *	1995-03-27	1997-08-26	Petrow; Vladimir	19-oxygenated steroids as therapeutic agents
US5678570A (en) *	1995-04-14	1997-10-21	The University Of North Carolina At Chapel Hill	Method of treating cardiac arrest
US5696103A (en) *	1995-11-17	1997-12-09	Syntex (U.S.A.) Inc.	Method for treating osteoporosis
DE19619036A1 (de) *	1996-04-30	1997-11-13	Schering Ag	Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US6043385A (en) *	1997-12-16	2000-03-28	Hoffman-La Roche Inc.	Vitamin D derivatives
GB9804861D0 (en)	1998-03-06	1998-04-29	Res Inst Medicine Chem	Chemical compounds
EP1123921A4 (en) *	1998-10-23	2003-08-20	Teijin Ltd	VITAMIN D 3 DERIVATIVES? AND MEDICINES FOR INFLAMMATORY RESPIRATORY DISEASES CONTAINING THEM
DE19935771A1 (de) *	1999-07-23	2001-02-01	Schering Ag	Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
ES2240159T3 (es)	1999-09-29	2005-10-16	Colotech A/S	Prevencion del cancer colorrectal.
US6703380B2 (en)	1999-09-29	2004-03-09	Colotech A/S	Prevention of cancer
WO2001030751A2 (en) *	1999-10-25	2001-05-03	Strakan Limited	USES OF 1,25-DIHYDROXY-5,6-trans VITAMIN D COMPOUNDS AND DERIVATIVES THEREOF
US7985744B2 (en) *	2000-06-15	2011-07-26	Chugai Seiyaku Kabushiki Kaisha	Vitamin D derivatives
US20080293647A1 (en)	2004-11-12	2008-11-27	Luciano Adorini	Combined Use Of Vitamin D Derivatives And Anti-Proliferative Agents For Treating Bladder Cancer
WO2007131364A1 (en) *	2006-05-16	2007-11-22	Mcgill University	Hybrid molecules having mixed vitamin d receptor agonism and histone deacetylase inhibitory properties
WO2009117831A1 (en) *	2008-03-27	2009-10-01	The Royal Institution For The Advancement Of Learning/Mcgill University	Hybrid molecules having mixed vitamin d receptor agonism and histone deacetylase inhibitory properties
US8987235B2 (en)	2011-05-17	2015-03-24	Wisconsin Alumni Research Foundation	N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-vitamin D analogs and their uses
WO2022059684A1 (ja) *	2020-09-15	2022-03-24	帝人ファーマ株式会社	側鎖に環状アミンを有するビタミンｄ誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4217288A (en) *	1977-03-24	1980-08-12	Wisconsin Alumni Research Foundation	Anti-vitamin D compounds
FR2426044A2 (fr) *	1978-05-19	1979-12-14	Wisconsin Research Foundation	Derives de la vitamine d3 ayant une activite anti-vitamine d
ATE74269T1 (de) *	1987-07-29	1992-04-15	Takeda Chemical Industries Ltd	Zellproliferationsinhibitor.
US5206230A (en) *	1991-06-05	1993-04-27	Daikin Industries, Ltd.	Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
EP0614455B1 (en) *	1991-11-07	1996-02-21	Research Institute For Medicine And Chemistry Inc.	Vitamin d amide derivatives

1992
- 1992-11-06 EP EP92922932A patent/EP0614455B1/en not_active Expired - Lifetime
- 1992-11-06 ES ES92922932T patent/ES2083771T3/es not_active Expired - Lifetime
- 1992-11-06 PL PL92303505A patent/PL171580B1/pl not_active IP Right Cessation
- 1992-11-06 SK SK522-94A patent/SK281302B6/sk unknown
- 1992-11-06 RU RU94044435A patent/RU2139276C1/ru not_active IP Right Cessation
- 1992-11-06 DK DK92922932.6T patent/DK0614455T3/da active
- 1992-11-06 AT AT92922932T patent/ATE134366T1/de not_active IP Right Cessation
- 1992-11-06 AU AU29014/92A patent/AU664213B2/en not_active Ceased
- 1992-11-06 CZ CZ19941112A patent/CZ288031B6/cs not_active IP Right Cessation
- 1992-11-06 KR KR1019940701503A patent/KR100271461B1/ko not_active Expired - Fee Related
- 1992-11-06 CA CA002121678A patent/CA2121678C/en not_active Expired - Fee Related
- 1992-11-06 WO PCT/EP1992/002577 patent/WO1993009093A1/en not_active Ceased
- 1992-11-06 JP JP50817993A patent/JP3282811B2/ja not_active Expired - Fee Related
- 1992-11-06 NZ NZ245041A patent/NZ245041A/en not_active IP Right Cessation
- 1992-11-06 DE DE69208478T patent/DE69208478T2/de not_active Expired - Fee Related
- 1992-11-06 US US08/211,722 patent/US5494905A/en not_active Expired - Fee Related
- 1992-11-06 HU HU9401372A patent/HU221008B1/hu not_active IP Right Cessation
1994
- 1994-05-06 NO NO941683A patent/NO305315B1/no unknown
- 1994-05-06 FI FI942114A patent/FI106119B/fi not_active IP Right Cessation
1995
- 1995-12-07 US US08/568,755 patent/US5686435A/en not_active Expired - Fee Related
1996
- 1996-04-09 GR GR960400996T patent/GR3019601T3/el unknown

Also Published As

Publication number	Publication date
CA2121678A1 (en)	1993-05-13
DE69208478T2 (de)	1996-09-05
CA2121678C (en)	2005-03-15
HUT67140A (en)	1995-02-28
WO1993009093A1 (en)	1993-05-13
FI942114L (fi)	1994-05-06
AU664213B2 (en)	1995-11-09
HU221008B1 (hu)	2002-07-29
PL171580B1 (pl)	1997-05-30
CZ288031B6 (cs)	2001-04-11
JPH07502499A (ja)	1995-03-16
AU2901492A (en)	1993-06-07
ATE134366T1 (de)	1996-03-15
KR100271461B1 (ko)	2000-11-15
SK52294A3 (en)	1994-11-09
CZ111294A3 (en)	1995-03-15
FI106119B (fi)	2000-11-30
US5494905A (en)	1996-02-27
ES2083771T3 (es)	1996-04-16
EP0614455B1 (en)	1996-02-21
SK281302B6 (sk)	2001-02-12
DE69208478D1 (de)	1996-03-28
RU2139276C1 (ru)	1999-10-10
FI942114A0 (fi)	1994-05-06
NO941683D0 (no)	1994-05-06
JP3282811B2 (ja)	2002-05-20
NZ245041A (en)	1995-03-28
US5686435A (en)	1997-11-11
GR3019601T3 (en)	1996-07-31
NO941683L (pl)	1994-06-27
HU9401372D0 (en)	1994-08-29
EP0614455A1 (en)	1994-09-14
NO305315B1 (no)	1999-05-10

Publication	Publication Date	Title
DK0614455T3 (da)	1996-03-18	Vitamin D-amidderivater
DK148484A (da)	1984-09-05	Guanidin-derivater
ES2176204T3 (es)	2002-12-01	Antidepresivos que contienen un derivado de xantina.
DK0696275T3 (da)	1998-11-09	Vitamin D-amid-derivater
FI894867A0 (fi)	1989-10-13	Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
NO932607L (no)	1994-01-21	Piperidinderivater og anvendelse av disse
ATE77083T1 (de)	1992-06-15	Benzamide protease-inhibitoren.
ES2126636T3 (es)	1999-04-01	Derivados del bencimidazol con actividad antidiabetica y antiagregante plaquetaria.
ES2057959T3 (es)	1994-10-16	Derivados de tienopiridina y composiciones farmaceuticas que los contienen.
ES2093091T3 (es)	1996-12-16	Derivado de glutation.
ES2021142B3 (es)	1991-10-16	Agentes antiarritmicos.
DE68906965D1 (de)	1993-07-15	Analgetische phenothiazinderivate.
ATE198890T1 (de)	2001-02-15	Antidepressiva
ES2021330B3 (es)	1991-11-01	Ciclohexilaminas fungicidas.
ES2068407T3 (es)	1995-04-16	Tratamiento de apneas durante el sueño con derivados de azapirona.
DE69014196D1 (de)	1994-12-22	3,6-diamino-2,5-pyrazindicarbonitril und ihre herstellung.
ATE120188T1 (de)	1995-04-15	15-deoxyprostaglandinderivat.
ATE15201T1 (de)	1985-09-15	Organophosphat-derivate.
AP9300580A0 (en)	1995-04-14	Oxa- and thiadiazole derivatives.
ES8506297A1 (es)	1985-07-01	Procedimiento para la obtencion de 1, 3, 5-tiadiazin-2-tioxo-4-onas 3, 6-disustituidas
ATE112781T1 (de)	1994-10-15	Polyglukosiden aus hydroxyalkylsorbit.