DK0614887T3 - Indolsulfonamider som antitumormidler - Google Patents

Indolsulfonamider som antitumormidler

Info

Publication number
DK0614887T3
DK0614887T3 DK94301671.7T DK94301671T DK0614887T3 DK 0614887 T3 DK0614887 T3 DK 0614887T3 DK 94301671 T DK94301671 T DK 94301671T DK 0614887 T3 DK0614887 T3 DK 0614887T3
Authority
DK
Denmark
Prior art keywords
antitumor agents
indolinesulfonamide
indolesulfonamide
chem
derivatives
Prior art date
Application number
DK94301671.7T
Other languages
Danish (da)
English (en)
Inventor
Gerald Burr Grindey
James Edward Ray
John Eldon Toth
Cora Sue Grossman
James Jeffry Howbert
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0614887T3 publication Critical patent/DK0614887T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK94301671.7T 1993-03-10 1994-03-09 Indolsulfonamider som antitumormidler DK0614887T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2909593A 1993-03-10 1993-03-10

Publications (1)

Publication Number Publication Date
DK0614887T3 true DK0614887T3 (da) 1997-10-20

Family

ID=21847185

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94301671.7T DK0614887T3 (da) 1993-03-10 1994-03-09 Indolsulfonamider som antitumormidler

Country Status (20)

Country Link
EP (1) EP0614887B1 (cs)
JP (1) JPH08507532A (cs)
KR (1) KR960700710A (cs)
AT (1) ATE154345T1 (cs)
AU (1) AU687042B2 (cs)
BR (1) BR9405997A (cs)
CA (1) CA2157801A1 (cs)
CZ (1) CZ232695A3 (cs)
DE (1) DE69403695T2 (cs)
DK (1) DK0614887T3 (cs)
ES (1) ES2102774T3 (cs)
FI (1) FI954213L (cs)
GR (1) GR3023827T3 (cs)
HU (1) HU218660B (cs)
NO (1) NO953557L (cs)
NZ (1) NZ263080A (cs)
PL (1) PL310558A1 (cs)
RU (1) RU2127259C1 (cs)
WO (1) WO1994020101A1 (cs)
ZA (1) ZA941500B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU709107B2 (en) * 1996-08-22 1999-08-19 Dong Wha Pharmaceutical Industrial Co., Ltd. Arylsulfonylimidazolone derivatives as an antitumor agent
JP2000247949A (ja) * 1999-02-26 2000-09-12 Eisai Co Ltd スルホンアミド含有インドール化合物
DE19919793A1 (de) 1999-04-30 2000-11-02 Bayer Ag Neue Sulfonamide
DE60316984T2 (de) * 2002-11-22 2008-07-17 Eli Lilly And Co., Indianapolis Benzoylsulfonamide als antitumor-mittel
TWI315304B (en) * 2006-08-31 2009-10-01 Univ Taipei Medical Indoline-sulfonamides compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1240866B (de) * 1961-06-29 1967-05-24 Heyden Chem Fab Verfahren zur Herstellung von Indolin-6-sulfonylharnstoffen
IL80032A (en) * 1985-09-23 1992-07-15 Lilly Co Eli Anti-tumor phenyl-aminocarbonylsulfonamides,their preparation and pharmaceutical compositions containing them
US5116874A (en) * 1985-09-23 1992-05-26 Eli Lilly And Company Anti-tumor method and compounds
CA1331464C (en) * 1987-05-12 1994-08-16 Eli Lilly And Company Anti-tumor method and compounds
NZ238911A (en) * 1990-07-17 1993-10-26 Lilly Co Eli Furyl, pyrrolyl and thienyl sulphonyl urea derivatives, pharmaceutical compositions and intermediates therefor
US5169860A (en) * 1992-03-13 1992-12-08 Eli Lilly And Company Antitumor compositions and methods of treatment

Also Published As

Publication number Publication date
EP0614887A1 (en) 1994-09-14
BR9405997A (pt) 1995-12-19
AU6363894A (en) 1994-09-26
EP0614887B1 (en) 1997-06-11
FI954213A0 (fi) 1995-09-08
GR3023827T3 (en) 1997-09-30
HU218660B (hu) 2000-10-28
CZ232695A3 (en) 1996-01-17
ATE154345T1 (de) 1997-06-15
WO1994020101A1 (en) 1994-09-15
HUT72897A (en) 1996-06-28
HU9502627D0 (en) 1995-11-28
AU687042B2 (en) 1998-02-19
ZA941500B (en) 1995-09-04
RU2127259C1 (ru) 1999-03-10
FI954213A7 (fi) 1995-10-11
NZ263080A (en) 1996-12-20
CA2157801A1 (en) 1994-09-15
KR960700710A (ko) 1996-02-24
NO953557L (no) 1995-11-02
PL310558A1 (en) 1995-12-27
DE69403695D1 (de) 1997-07-17
JPH08507532A (ja) 1996-08-13
FI954213L (fi) 1995-10-11
DE69403695T2 (de) 1997-10-30
NO953557D0 (no) 1995-09-08
ES2102774T3 (es) 1997-08-01

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